Paul L @PaulLMMA
Variant Finder - Citizen Scientist - Nursing Student Niagara, Ontario, Canada Joined October 2011-
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Important re indoor risk: "aerosolized virus and CO2 have the same origin, and their mutual interaction increases the overall risk ... increased [CO2(g)] itself may increase the likelihood of successful transmission by increasing viral viability." nature.com/articles/s4146…
BREAKING🔔 A new study from G2P-Japan🇯🇵 is out at bioRxiv @biorxivpreprint. We elucidated the virological characteristics of SARS-CoV-2 KP.2 - a progeny of JN.1. Please RT🔥 1/ biorxiv.org/cgi/content/sh…
The FLiRT variant KP.2 begins its takeover for Covid cases in the US, now accounting for 1 in 4 cases covid.cdc.gov/covid-data-tra…
I work with some incredible bioinformaticians that are dedicated to building and maintaining open-source bioinformatics workflows for the public health community. Check out the latest version of these workflows here!
I work with some incredible bioinformaticians that are dedicated to building and maintaining open-source bioinformatics workflows for the public health community. Check out the latest version of these workflows here!
.@WHO TAG-CO-VAC advises the use of a monovalent JN.1 lineage as the antigen in future formulations of #COVID19 #Vaccines Good Choice Better Choice - JN.1 + #FLiRT who.int/news/item/26-0…
Arbitrary limitations imposed on some researchers by nameless GISAID authorities remains a problem. I have strict limits on my account. I have no idea why. I'm going to have to spend >30 hours mindlessly clicking buttons & checking boxes in order to do large-scale analysis. 1/9
Arbitrary limitations imposed on some researchers by nameless GISAID authorities remains a problem. I have strict limits on my account. I have no idea why. I'm going to have to spend >30 hours mindlessly clicking buttons & checking boxes in order to do large-scale analysis. 1/9
Update 4/25: Ontario's covid wastewater signal is rising (preliminary data in grey). This appears to be mainly driven by the Greater Toronto Area (GTA). Source: @PublicHealthON - see GTA in reply
Fantastic study from the Grubaugh Lab on dengue virus dynamics! They demonstrate how local introductions can lead to large outbreaks, highlighting the need for traveler-based surveillance.
Fantastic study from the Grubaugh Lab on dengue virus dynamics! They demonstrate how local introductions can lead to large outbreaks, highlighting the need for traveler-based surveillance.
The next PM of Canada. Book it.
#Ottawa SARS-CoV-2 wastewater trends as of: April 21. Pandemic highlighting past year (A), blue line is weekly average; Past year highlighting last 2 months (B); Past 2 months (C), inferred case incidence (D), and Reff (E) determined with github.com/phac-nml-phrsd…
New study. We compared the immune response of XBB and JN.1 in human infections to evaluate the necessity for #SARSCOV2 vaccine updates Results: JN.1 exposure induces higher neutralization against emerging mutants, including FLiRT (JN.1+346T+456L) and KP.3 biorxiv.org/content/10.110…
@Nucleocapsoid @StuartTurville I'm also curious if the cleaved/uncleaved ACE2 story is related to JN.1's incr use of heparan sulfate as a co-receptor, which @yunlong_cao & @GuptaR_lab demonstrated. The RBM has become increasingly positively charged, & JN.1 is the pinnacle of this trend x.com/longdeserttrai…
@Nucleocapsoid @StuartTurville I'm also curious if the cleaved/uncleaved ACE2 story is related to JN.1's incr use of heparan sulfate as a co-receptor, which @yunlong_cao & @GuptaR_lab demonstrated. The RBM has become increasingly positively charged, & JN.1 is the pinnacle of this trend x.com/longdeserttrai…
Neutralisation antibody trajectory throughout the pandemic. A 🧵 1- In 2020 one of there were two therapeutics that were rapidly developed and tested. The first was convalescent plasma from those who recovered from infection and then there was a concentrated version called IVIG.
It's been getting on for a year since I wrote this thread - heres a bit of an update of where we are with the evidence for mammal-to-mammal transmission of H5N1s. x.com/peacockflu/sta…
It's been getting on for a year since I wrote this thread - heres a bit of an update of where we are with the evidence for mammal-to-mammal transmission of H5N1s. x.com/peacockflu/sta…
An immunocompromised man, who was chronically infected with BA.1.17 for more then 1,5 years, until unfortunately he died because of his underlying disease, was tested repeatly. 50 nucleotides mutated Big thanks to this patiënt and to Magda Vergouwe, @Viroloog , @Flahless1 et al.
An immunocompromised man, who was chronically infected with BA.1.17 for more then 1,5 years, until unfortunately he died because of his underlying disease, was tested repeatly. 50 nucleotides mutated Big thanks to this patiënt and to Magda Vergouwe, @Viroloog , @Flahless1 et al. https://t.co/8GBlvKc3YC
Excited to release our research on rational identification of broadly neutralizing Abs against fast-evolving pathogens. Besides Richard's high-level introduction, I'd like to introduce some details in this thread for experts who are interested.
Excited to release our research on rational identification of broadly neutralizing Abs against fast-evolving pathogens. Besides Richard's high-level introduction, I'd like to introduce some details in this thread for experts who are interested.
𝗟𝗼𝗻𝗴𝗶𝘁𝘂𝗱𝗶𝗻𝗮𝗹 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗼𝗳 𝗴𝗲𝗻𝗼𝗺𝗶𝗰 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗦𝗔𝗥𝗦-𝗖𝗼𝗩-2 𝗶𝘀𝗼𝗹𝗮𝘁𝗲𝘀 𝗳𝗿𝗼𝗺 𝗽𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝘁 𝗖𝗢𝗩𝗜𝗗-19 𝗽𝗮𝘁𝗶𝗲𝗻𝘁 𝘯𝘦𝘸 𝘴𝘵𝘶𝘥𝘺 𝘧𝘳𝘰𝘮 𝘰𝘶𝘳 𝘧𝘳𝘪𝘦𝘯𝘥 @SystemsVirology cell.com/iscience/fullt…
T. Ryan Gregory @TRyanGregory
83K Followers 1K Following Professor of evolutionary biology. I would like there to be less death, pestilence, war, and famine. Assume sarcasm. No one could have foreseen this. He/him.Ryan Hisner @LongDesertTrain
22K Followers 838 Following Teacher "Be ruthless with systems and be kind to people." Michael Brooks, 1983-2020Bloom Lab @jbloom_lab
48K Followers 1K Following Lab studying molecular evolution of proteins and viruses. Affiliated with @fredhutch @HHMINEWS @uwgenome. @jbloomlab@bskyFederico Gueli 🏳�.. @siamosolocani
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13K Followers 517 Following Never be afraid to raise your voice for honesty and truth and compassion against injustice and lying and greed. William Faulknergianluca c 🏴☠.. @gianlucac1
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11K Followers 648 Following Writer/Editor at MMA Uncensored, formerly of Bloody Elbow. Find me on Substack. Face-punch history buff & host of the MMA Vivisection. I also like movies.smoogy @smoogymma
5K Followers 818 Following Graphic Designer; Semi-Pro MMA Scout; Co-Creator of the World MMA Scouting Report. Buy my rashguard! https://t.co/Dk43tE3Wrg…Shawn Bitter @mmawizzard
5K Followers 4K Following 28 | Prospect wiz | Cageside Press | Paypal- [email protected] | Email- [email protected] | My Patreon- https://t.co/8o6baisnspChris Rini @RiniMMA
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541 Followers 3K Following love is a living thing 💥💚 I take it as world super power example this conflicts between countries it's because of the lack of love 💫 let's love one anotherArthur Seat @zeeofgee
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2 Followers 66 FollowingPureology @Welnesschick
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69 Followers 448 Following We offer academic writing services on essays, assignments, online classes. LITERATURE, PHILOSOPHY, PSYCHOLOGY, NURSING, JOURNALISM, BUSINESS MANAGEMENT etc.Kirsten Gillespie @KirstenGilles13
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39 Followers 5K FollowingRed-Haired @Jeighez294640
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694K Followers 589 Following physician-scientist, author, editor. Ground Truths: https://t.co/YhatcBT0hAFederico Gueli 🏳�.. @siamosolocani
5K Followers 3K Following Quanto era bella la pace Brotherdog = a will of peace while seeking variants RT =not endorsment! If i must die, you must live to tell my story (Refat Alareer)Tom Peacock @PeacockFlu
51K Followers 1K Following Virologist. Viruses, Influenza, Coronaviruses and SARS-CoV-2. Typos are intenitonal. Fellow at @Pirbright_Inst and @ImperialInfectcaposa @Grabaka_Hitman
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17K Followers 701 Following Assistant Dean of Research and Associate Professor, NYITCOM at Arkansas State University | My Tweets are my ownJosette Schoenmakers @JosetteSchoenma
7K Followers 402 FollowingJWeiland @JPWeiland
27K Followers 189 Following Scientist. Infectious disease modeler. Tweets and spelling mistakes are my own Models and analysis seen on @Newsweek @Fortunemagazine @FaceTheNation @NYMagYunlong Richard Cao @yunlong_cao
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16K Followers 35 Following Data Visualisation and Data Integration specialist - Melbourne, Australia 🦣 https://t.co/hTTQENGW1m 🟦 mikehoney 🪡 mike_honey__ https://t.co/2glkTu9f2uThe Sato Lab (Kei Sat.. @SystemsVirology
20K Followers 2K Following 東京大学医科学研究所システムウイルス学分野教授 The Genotype to Phenotype Japan (G2P-Japan) Consortium主宰 一般社団法人G2P-Japan代表理事 週プレNEWSでコラム連載中→https://t.co/zLvSNcurTqMarcel Dorff 🇳🇱.. @BigMarcel24
93K Followers 5K Following Freelance Journalist @Eurosport_NL @UFCopEurosport Dutch Events adm. @Tapology. @MMAOddsBreaker pod with @MMAdamMartin. 100% AFC Ajax. #Indisch #MMADNA❤Emmanuel @ejustin46
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74K Followers 2K Following Assistant Professor of Dermatology @McGillMed. MD/residency @med_umontreal. Fellowship @HarvardDerm. Focus: complex medical dermatology and medical education.gianluca c 🏴☠.. @gianlucac1
20K Followers 6K Following Banca Centrale Rettiliana -Hayek Brigade - HIC SUNT LEONES - Za naszą i waszą wolność - RT=Reverse Trascriptase https://t.co/9SAVCyPqL2Tom Wenseleers @TWenseleers
23K Followers 1K Following Professor @KU_Leuven - evolutionary biology, theoretical biology & biostatistics. Working with #insects, #microorganisms (incl. Covid) & #humans.Marc Johnson @SolidEvidence
31K Followers 131 Following Molecular virologist, Professor, sewage sage and wastewater wizard.Aris Katzourakis @ArisKatzourakis
37K Followers 2K Following Paleovirology, cross-species transmissions, evolution, genomics, viruses, selfish genes. UCU NEC, Branch Hon Sec, Oxford Biol. Tweets mine, retweets not.Theo Sanderson @theosanderson
14K Followers 1K Following Scientific researcher in pathogen genetics. Previously: @GoogleAI, @sangerinstitute 🧪 🤖 🖥️ @[email protected] / @theo.io on blueskyHopeStarMasacre @MscreStarHope
2K Followers 3K Following its alright… im just dying is all…// writer and performer of the theatric kind // disabled as fuck with #LC #ME #POTS #MCAS & more // antizionist ✡️ 🇲🇽🏳️⚧️Amy DeBellis @lapis_lazuli11
2K Followers 665 Following ALL OUR TOMORROWS @CLASHBooks 2025 🖤 Words in @fracturedlit @ghostparachute @flashfroglitmag @monkeybicycle @pinchjournal One of #millionsmissing ♿️𝓝𝓸𝓼𝓯𝓮�.. @FourWinns298
20K Followers 559 Following That burning is pleasurable, that which enlightens the darkened path of others Forsan et haec olim meminisse iuvabitNukit @NukitToBeSure
7K Followers 299 Following Nukit at https://t.co/62nBfO0NBA Distributing The Future More Evenly.Canada Healthwatch �.. @CanHealthwatch
6K Followers 1K Following Canada's hub for health news. Newsletter: https://t.co/TFNBBIjTTnGinny @ginflo2
183 Followers 2K Following stocks, caregiving, parenting, advocate for clean air #CorsiRosenthalBox until the ventilation revolution finally arrives #cuetheengineers 😷💨📦 💉Huachuan Shi @Aurora031027
54 Followers 228 FollowingMike Cousineau @MikeCousineau5
1K Followers 2K Following Most people aren't really afraid of the dark. They are afraid of what may appear if the lights suddenly go on.War Mapper @War_Mapper
375K Followers 240 Following Map updates for the war in Ukraine with occasional updates for other conflicts. https://t.co/JS7686HyV9Future @UseBy2022
4K Followers 1K Following Pretending its gone doesn't actually make it go away. It's like closing your eyes so the monster won't see you. Me, honestly I'm just some dick with a phone.executive of dysfunct.. @TheTiniestMeep
735 Followers 1K Following my number one goal in life is to hug a cow. I have yet to achieve this goal. she/her. real ADHD hours who up. ⭕🚀 #covidisairborne #maskupFriesein @Friesein
8K Followers 6K Following Clean air is a human right. SARS2 is a severe pathogen disabling millions. Let's use scientific modeling and engineering to solve both. Listen to patients.Illia Ponomarenko �.. @IAPonomarenko
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19 Followers 30 FollowingweidaCN🇨🇳 @BStubborn98600
41 Followers 105 FollowingChaoran Chen @ChaoranChen_
364 Followers 18 Following PhD student at @ETH_en and developer of @GenSpectrum哔王🇨🇳🇷�.. @404_NotFoundWTF
48 Followers 189 Following Keyboard politician, amateur virus tracker, proposer of FL.2.3, GW.1, FL.21.2, HK.3.2 and JN.3.2 #FuckRussia #FuckIsrael风云梦远 @SuperTY1995
69 Followers 51 Following The climate,the world. NJU/Global climate change/Earth science/Typhoon~Hynn SpylorFearuncle @real_Fearuncle
1K Followers 5K Following 19| A 3x Featured Fortnite map maker| 1.3 Million + plays Use Code: fearuncle #ad |Creator of @CreepyPayday| Younked pfp from @evanticklesNkRMnZr @NkRMnZr
83 Followers 87 FollowingDr. Brian Poe @PoeBrianL
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349 Followers 1K Following laboratory Rat 💉🐁, CBRNe analyst, ☠️ Epidemic Intelligence Officer .🏨Tweets personal viewsNick Tsergas @nicktsergas
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1K Followers 3K Following Microbiologist working in public health. ECDC EUPHEM alum. Interests: Neisseria, enterics, AMR, SARS-CoV-2, mol/genomic epi, WGS, R. Views my own. 🇮🇪🧬🦠🥼Marc Perry @mdperry.b.. @mdperry
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3K Followers 2K Following Canadian from Saskatoon living in rural Bourgogne, France. 🇨🇦 🇫🇷 Scientist. Farmer. Traveler. @usask alumnus. Loves gardening & fancy cakes. He/him/il.Harry Spoelstra @HarrySpoelstra
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18K Followers 5K Following I have Common Variable Immune Deficiency. @IAGovernor called me “you people” on live TV. I make graphs & ask people to wear a respirator. Hubs: @AurielWilletteCanada Strong Masks @canadastrong
16K Followers 1K Following Made in Canada N95 & KN95 respirators with incredible fit, filtration, comfort, & overnight shipping. We donate for every sale. #BringBackMasks #WearARespiratorIan Weissman, DO @DrIanWeissman
41K Followers 37K Following Radiologist @DeptVetAffairs #AdvocatingForPatients #PublicHealth #Activist. Chair, @RadiologyACR #PFCC Cmte & CSC #Leadership. https://t.co/nQcljO5En9🇪🇺 Dr Joe Pajak.. @JoePajak
21K Followers 15K Following 𝙋𝙝𝘿 ⚛️ 𝙖𝙞𝙧 𝙚𝙣𝙩𝙧𝙖𝙞𝙣𝙢𝙚𝙣𝙩. 🏥NHS FT trust governor: 🌬Improve infection prevention and control! Petition: https://t.co/kIztDrpAjF.Christin Carlano 🪱 @CCarlano
328 Followers 2K Following fiber art person, horror enjoyer, ADHD gremlin, she/they, covid-conscious, likes weird shit.Infectious Disease Tr.. @HmpxvT
30K Followers 10K Following Sharing reports on disease outbreaks, from bird flu to Ebola. Follow this account if you want to be the first to know when a dangerous outbreak is brewing.DrJames @YorkU (he/hi.. @jasmith_yorku
9K Followers 6K Following Engineering professor at York University. Not an HVAC, PPE or Air Quality expert. Mastodon: @[email protected] & @[email protected]Chuck Pfarrer | Indic.. @ChuckPfarrer
170K Followers 1K Following Former SEAL Team 6 Squadron Leader, Conflict Correspondent, Mriya Report host, NYT Best Selling author, Hollywood screenwriter, dad husband & epic snowboarder.OSINTdefender @sentdefender
1.1M Followers 793 Following Open Source Intelligence Monitor focused on Europe and Conflicts across the World. RT ≠ Endorsement. Want to Support my Work? https://t.co/PcUbewvWPr👀
Update on the massive multidisciplinary 400 references review article on respirators/masks led by @trishgreenhalgh and @Globalbiosec - we have been correcting the proofs. Publication getting closer!
Same, Elmo. Same.
Many Canadian teachers can access CO2 monitors at their local library. If you’re interested in working through some citizen science with your students please reach out if you need help. @CAVI_CO2
It is a great day for ground-breaking research!! Teachers: The higher the CO2 levels in your classroom, - the LONGER Cov!d stays floating in the air - the longer the virus stays infectious - the greater the risk for transmission Do you know the CO2 levels in your classroom?
6) ...as the predominant emerging variant with properties of both high infectivity and immune evasion. Thanks for reading 🙏
5) This increased immune evasion partially explains KP.2's higher Rε. By early April, KP.2 reached 20% variant frequency in the UK. In conclusion, KP.2's spike protein mutations enhance its transmission and immune resistance abilities, making it a rising global threat ...
𝙑𝙞𝙧𝙤𝙡𝙤𝙜𝙞𝙘𝙖𝙡 𝙘𝙝𝙖𝙧𝙖𝙘𝙩𝙚𝙧𝙞𝙨𝙩𝙞𝙘𝙨 𝙤𝙛 𝙩𝙝𝙚 𝙎𝘼𝙍𝙎-𝘾𝙤𝙑-2 𝙆𝙋.2 𝙫𝙖𝙧𝙞𝙖𝙣𝙩 𝘕𝘦𝘸 𝘪𝘯𝘵𝘦𝘳𝘦𝘴𝘵𝘪𝘯𝘨 𝘴𝘵𝘶𝘥𝘺 𝘰𝘧 @SystemsVirology 𝘛𝘩𝘢𝘯𝘬𝘴 𝘵𝘰 𝘒𝘦𝘪 𝘚𝘢𝘵𝘰 🙏 biorxiv.org/content/10.110…
S:A475Vの波も日本は遅れているためXDQ.1のS:A475Vに勢いがある 475VはJN系統とは相性よくなさそうだけど相性の良かったXBBとの組換え体は合いそうね XDK.1 + S:A475Vが気になるところ github.com/sars-cov-2-var…
島国日本という変異の最終処分場 変異株が遅れてやってきて最後まで残る形 BA.5.2系統のBFやCK 少し前のFKやXBC *FK.1.1が最近カナダで1件でてるのが気になるところ
..add early nextstrain builds and insights from @LouiseHMoncla x.com/louisehmoncla/…
In response to the H5N1 infections in cows and now a human in Texas, we've just updated our North America specific H5Nx Nextstrain build with the cow and goat sequences, which are viewable under "Species-grouped: Ruminant": nextstrain.org/groups/moncla-…. A few notes.
Several #VariantHunters: @EmilyAnne_Smith, @PeacockFlu, @shay_fleishon and others shared early insights.. especially highlighted the sequence from the human specimen... x.com/emilyanne_smit…
This tree shows divergence in the HA gene. Note that the HA gene segments for all of the samples from TX dairy cattle are nearly identical. The recent human case from TX falls within a clade that contains those dairy cattle samples, as well as samples from wild birds in TX 2/7
The NDP Pharmacare Plan will be life-changing. Whether you're a student or a senior - a mom, dad, or a grandparent - no matter your income - you'll have access to medication that you need and deserve. Pierre Poilievre wants to block it - but I won't let him.
Everyone should save $79.99 by not paying for UFC 301.
April 26th update: Infection rates still decreasing, down 10% this week. Pirola with FLiRT mutations now at ~40%. 🔸180,000 new infections/day 🔸~2.78 avg total infections per capita across the US 🔸1 in every 185 people currently infected
Twitter has suspended Nelson Mandela's grandson, as he's about to set off on the Freedom Flotilla to take aid to Gaza.
@RajlabN The confirmation: x.com/harryspoelstra…
🔥"These results suggest that KP.2 is one of the most immune-evading variants to date, and this increased immune evasion partly explains the increased Re of KP.2." 🧵👇 ➡️ CAUTION ! Thanks @SystemsVirology for your great work! 👏
Proportion of JN.1 + #FLiRT⬆️👀 2/n
🔥"These results suggest that KP.2 is one of the most immune-evading variants to date, and this increased immune evasion partly explains the increased Re of KP.2." 🧵👇 ➡️ CAUTION ! Thanks @SystemsVirology for your great work! 👏
BREAKING🔔 A new study from G2P-Japan🇯🇵 is out at bioRxiv @biorxivpreprint. We elucidated the virological characteristics of SARS-CoV-2 KP.2 - a progeny of JN.1. Please RT🔥 1/ biorxiv.org/cgi/content/sh…
Statement on the antigen composition of COVID-19 vaccines by @WHO The TAG-CO-VAC advises the use of a monovalent JN.1 lineage as the antigen in future formulations of COVID-19 vaccines who.int/news/item/26-0…