Outbreak Updates @outbreakupdates
Infectious diseases and Pathogens. Latest reports. DM me about interesting stories. Toronto, Ontario Joined November 2022-
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#H5N1 #LessonLearned - Domestic and Farm cats! Common theme among H5N1 clade 2.3.4.4b infected Cats: - Present multiple symptoms almost immediately - Neurologic, Respiratory, rapid decline leading to death (or compassionate euthanasia) - Pick PB2 mammalian adaptations 1/n
"The findings highlight the variant-specific replication differences in human colonoids, providing insights into the enteric tropism of Omicron and its relevance to long COVID symptoms." 📌mdpi.com/1999-4915/16/4…
Well
Wow An amyloidogenic fragment of the SARS CoV-2 envelope protein promotes serum amyloid A misfolding and fibrillization biorxiv.org/content/10.110…
KP.2 is one of the most immune-evading variants to date
More than 150 people in West Virginia exposed to measles abcnews.go.com/Health/150-peo…
Another interesting point to note, the sequence from the human specimen (from Texas) contains the adaptation signature mutation PB2 E627K but lacks that PB2 M631L prevalent in all the cattle sequences!
Another interesting point to note, the sequence from the human specimen (from Texas) contains the adaptation signature mutation PB2 E627K but lacks that PB2 M631L prevalent in all the cattle sequences!
Blood transcriptomic analyses reveal persistent SARS-CoV-2 RNA and candidate biomarkers in post-COVID-19 condition thelancet.com/journals/lanmi…
Legend
Use a 2-meter-long straw?
We are still far, far from a direct threat to humans. But, the idea of a virus like H5N1 moving back and forth between the reservoir in birds, and the global human food supply chain, is not a welcome development.
We are still far, far from a direct threat to humans. But, the idea of a virus like H5N1 moving back and forth between the reservoir in birds, and the global human food supply chain, is not a welcome development.
I am so proud of our transplant team at @UNMHSC , @UNMHospital @UNM of which I am the least smart member. One of my goals when I became chief of the Neph Group in 2017 was achieved yesterday. And we achieved through kickass team work during a pandemic. cmcnetworkmanagementtool.uhc.com/clarity-fhcp/s…
The H5N1 milkshakes are safe. But wash your hands. -CDC
Finding H5N1 bird flu (though presumibly inactivated via pasteurization) in the grocery store milk supply does not fill me with confidence that we have this situation under control at the moment.
Finding H5N1 bird flu (though presumibly inactivated via pasteurization) in the grocery store milk supply does not fill me with confidence that we have this situation under control at the moment.
2024 Exponential Bingo ✅
I dare you
T. Ryan Gregory @TRyanGregory
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Lmao.
Nemat Shafik - @Columbia Prez only has 1 well-cited publication in her life, in Oxford Econ Papers 1994. This paper is lifted almost entirely from a 1992 report coauthored with consultant not credited in the publication. This is wholesale intellectual theft, not subtle plagiarism
eurekalert.org/news-releases/… ARDD 2024 is set to feature a stellar lineup. Maxwell Biosciences, along with esteemed academic institutions, clinicians, industry leaders, investors, and pharmaceutical companies, will contribute to rich dialogues and present new research in the field of…
I appreciate the recent PCR data concerning pasteurization and H5N1 fragments. Similar to a large pooled sample, finding viable virus (culturable) might not be straightforward...
No reason to doubt #Pasteurization But if you're skeptical, just boil your milk, let it cool, and use as needed (I do it all the time). #Milk boils at around ~212°F.
Kale infection alert ! @ChristosArgyrop
Another interesting point to note, the sequence from the human specimen (from Texas) contains the adaptation signature mutation PB2 E627K but lacks that PB2 M631L prevalent in all the cattle sequences!
One big question has been whether these cattle viruses carry known, mammal-adaptive mutations. None of the cattle sequences have PB2 E627K, but all have M631L, an alternative, putative adaptive mutation. nextstrain.org/avian-flu/h5n1…
We are still far, far from a direct threat to humans. But, the idea of a virus like H5N1 moving back and forth between the reservoir in birds, and the global human food supply chain, is not a welcome development.
OK, I think we're close to decisive evidence that US bovine H5N1 had a single origin from birds, and that when related viruses from birds *have* been found, they are jumps from cattle back into birds. Grackles, blackbirds, chickens all show mammalian adaptation like PB2 M631L.
I am so proud of our transplant team at @UNMHSC , @UNMHospital @UNM of which I am the least smart member. One of my goals when I became chief of the Neph Group in 2017 was achieved yesterday. And we achieved through kickass team work during a pandemic. cmcnetworkmanagementtool.uhc.com/clarity-fhcp/s…
Finding H5N1 bird flu (though presumibly inactivated via pasteurization) in the grocery store milk supply does not fill me with confidence that we have this situation under control at the moment.
This isn't good, folks. I'm not worried about H5N1 transmission to humans (yet) but the @USDA pathetic lack of transparency, how long it took for the genomes to be released, lack of testing asymptomatic cattle...... All detracts from "confidence"
Hey, CDC. Stop testing the milk. Start testing every single farmworker. I dare you.
The lasting economic consequences of colonialism in Europe, 500-1300 years ago: an example of Spain. upo.es/economia/econo…
@RickABright @USDA @USDA_APHIS @GISAID Lack of transparency is the mother of all FAFO. Do better
@theNoozDotXYZ @0bj3ctivity @BarryESharp Who said I’m angry?
Thank you, @PeacockFlu Tick Tock... Several new human cases in China and India, plus the Psittacosis outbreak in Brazil should be considered🙏🏻 @outbreakupdates @ejustin46
It's been getting on for a year since I wrote this thread - heres a bit of an update of where we are with the evidence for mammal-to-mammal transmission of H5N1s. x.com/peacockflu/sta…
Even the smartest people in the world have not yet contemplated the downstream effects of normalizing stupidity.
Tick Tock.... @outbreakupdates Cards ready???
New pandemic 'expected' as human-to-human bird flu of 'great concern' to WHO The World Health Organisation's chief scientist Dr Jeremy Farrar has claimed a new pandemic is 'expected' after a surge in cases of deadly human-to-human bird flu. dailystar.co.uk/news/world-new…