Efthymios Kalafatis @lifeanalytics
Data Scientist, Patent owner of Artificial Intelligence-assisted methodology for Medical Discovery. Tweets are mine/not medical advice or endorsements. Joined May 2009-
Tweets2K
-
Followers5K
-
Following3K
-
Likes3K
In 2015, the first AI-generated hypothesis on #MECFS and several other syndromes was shared with some researchers. Are we currently looking at the bigger picture? Are there other syndromes -apart from #MECFS and #LongCOVID having Post-exertional malaise as a symptom?
So encouraging to see our recent paper has "more views than 80% of all Frontiers articles." It simply highlights the need to delve deeper into ME/CFS, EDS/hEDS/HSD, MCAS, POTS, Lyme, Dysautonomia, and Long COVID to help a diverse group of patients with comorbidities.#MECFS
@fereshtehjahan1 @JanetDafoe @DafoeWhitney @OpenMedF @azuravesta @hroest @SnyderShot 2/ Proposed Framework for Personalized Severity Assessment in ME/CFS to Capture Variation in ME/CFS Severity and Life Impairment across Patients and Time. from: frontiersin.org/journals/immun… #MEcfs #CFS #PwME #SevereME #SevereMECFS #SevereCFS #VerySevereME
Triple anticoagulant therapy, day 50. For a week, I've seen marked improvement in ortostatic intolerance but none in exertion intolerance. I don't crash anymore but I get dead tired. If you are on triple, I wonder if you experience the same. #LongCovid #MECFS
We cannot afford to miss this kind of information. I had no idea about it. Hepatitis B vaccination appears to be reported by 57% of respondents as having triggered #MECFS :
We cannot afford to miss this kind of information. I had no idea about it. Hepatitis B vaccination appears to be reported by 57% of respondents as having triggered #MECFS :
From the paper: "It is possible the EDS patients as a group may display higher variant allele frequencies which result in alteration of hepatic metabolism of other LA (e.g., mepivacaine metabolized by CYP1A2/3A4 and bupivacaine metabolized by CYP3A4)" however this was not tested.
From the paper: "It is possible the EDS patients as a group may display higher variant allele frequencies which result in alteration of hepatic metabolism of other LA (e.g., mepivacaine metabolized by CYP1A2/3A4 and bupivacaine metabolized by CYP3A4)" however this was not tested.
Time for a poll : In which of the areas listed below should #MECFS research be directed?
Hannah Davis @ahandvanish
60K Followers 4K Following Research, algorithmic music, machine learning/AI, anti-bias in AI data. #LongCovid research & advocacy @patientled. they/them. DMs rarely checkedIt'sME(Jaime) @exceedhergrasp1
20K Followers 5K Following Director of Sci & Med Outreach, #MEAction Stanford Med #ME, #EDS, #POTS, #LongCOVID Views my own [email protected]Anil van der Zee © @AnilvanderZee
9K Followers 824 Following Former professional ballet dancer | Bed/sofa-bound M.E. patient | Using Twitter to raise awareness for #MyalgicE | #art2cureME #pwme #millionsmissingME/CFS News @MECFSNews
15K Followers 712 Following News, interesting information and commentary on ME/CFS. My bluesky account is @mecfsnews.bsky.social Looking for paid ME/CFS related work.Dr Asad Khan FRCP FRA.. @doctorasadkhan
28K Followers 3K Following Lung Dr on pause since Nov 20 #LongCovid #POTS #MCAS #HSD #pwME #Aotearoa Views my own; Retweets≠endorsements #freepalestine #TeamClots ZIONISTS WILL BE BLOCKEDMartin Hippe @pausedME
7K Followers 474 Following East Westphalia by Nature ⎮Lawyer by Profession | #Musikrecht | #MECFS | @Mirame_Arts | No medical advice!Billy Hanlon @bhanlon15
12K Followers 11K Following Director of Advocacy & Outreach, Minnesota ME/CFS Alliance | Long COVID AllyNaomi Harvey PhD #Wea.. @Naomi_D_Harvey
15K Followers 4K Following Zoologist. She/her. 22yrs with ME/CFS. Pro-vax but vaccine injured. Life on pause (views my own - unemployed) ♿️ https://t.co/YeMrEWwEg5Tess Falor, Ph.D. | @.. @tessfalor
9K Followers 5K Following 🚀Space physicist➡️#MECFS researcher🧪 Founder - Renegade Research @renegaderes - RemissionBiome @remissionbiome ✨Serendipity Meets Preparation✨Dan Wyke 🦠➡️�.. @Dan_Wyke
13K Followers 6K Following M.E. patient, advocate, person-centred counsellor (see link), recovering poetBea is Chronically Pe.. @Be_Kinderr
11K Followers 3K Following Chronic Illness Researcher. Science of #MECFS #LongCovid #POTS #EDS #MCAS CCI SFN Lyme etc & How They Connect🕵🏻♀️Scientist/Advocate [email protected]Herbert Renz-Polster @RenzPolster
8K Followers 504 Following physician-researcher, paediatrician, ME/CFS since 2016. This account is about science, esp. CFS (may also visit: @kinderverstehen: on child development (German)Sibylle Dahrendorf �.. @sibylle_berlin
6K Followers 3K Following Once a filmmaker now stuck in horizontal hell | #SmallFiber #BigPain #POTS #MCAS #CCI #Lyme #FQToxicity #ME I Stop denial of #ComplexChronicIllnesses IAdam @ABrokenBattery
6K Followers 1K Following Severe ME patient currently on a 10% battery, the gas goes out more than I do. I also compile ME/CFS Awareness videos.Amy Proal, PhD @microbeminded2
29K Followers 5K Following Microbiologist at PolyBio Research Foundation: helping research teams collaborate on infection-associated chronic disease #me #longcovid #lyme #eds @polybioRFCort Johnson @CortJohnson
10K Followers 1K Following Founder of Health Rising /Phoenix Rising - Chronic Fatigue Syndrome (ME/CFS)/Fibromyalgia/Long COVID journalist/blogger - ME/CFS/FM patient for 40 plus yearsMichael Stingl @neurostingl
16K Followers 1K Following Facharzt für Neurologie ME/CFS ▪ Long Covid ▪ Nervenultraschall ▪ ENG/EMG ▪ Hirngesundheit ▪ TelemedizinWinston Blick @winstoncb
3K Followers 901 Following #MECFS post-viral #longhauler | ally of #LongCOVID | quoter of @mecfsquotes | previously, 🚵🏼♂️ 🏂 🏃🏻🏕️ 📖Vijay Iyer PhD @vijayiyer312
3K Followers 2K Following Patient advocating science for #mecfs & #dysautonomia (incl via #longcovid & #postvac).👷🏾♂️Support #neuroscience users & use cases of @MATLAB. Tweets my own.PwME 4 bioMEdical res.. @ValeBodi
4K Followers 2K Following Surviving #MyalgicE #AAG to tell the story, patient&advocate w/ a JD, into: MEdicine, Social justice & the Arts, Human neutrino/MEdical apolide/gnarled PacerLongLonghauler @sketchingwitht
118 Followers 199 FollowingSafa Diab @SafaDiab1297930
71 Followers 5K FollowingGabriela Kozan @KozaGabrie
70 Followers 5K Followingvasilis k @i_Vasilis
226 Followers 3K FollowingVC @vctw97
7 Followers 92 FollowingMichal Tal, PhD @ImmunoFever
13K Followers 10K Following Immunoengineer @MITdeptofBE captivated by #inflammation, #SexDifferences #Lyme, #COVID, and planetary health. prev/ @Yale, @Stanford. @immunofever.bsky.socialRichie Rich @RichieRich0815
52 Followers 296 Following Inquisitive mind, loves nature and doing sports. Life on pause due to #LongCovid with #PEMGabriela Freemon @FreemoGabrie
13 Followers 3K FollowingThe Real GhostPepper @GraggLadon
29 Followers 286 Following Servant of the Lord Jesus Christ. Looking for that blessed hope and the return of our great God and our Savior Jesus Christ (Titus 2:13) - Maranatha!Emilina @Emilina1639841
14 Followers 162 FollowingMolly Myers @mollistan
3K Followers 5K Following Woman=adult human female. Anti-woke but not indifferent to injustice. likes ev psych, free speech & debate, atheist, momx2, anti-zionist. politically homelessOlive Turnbaugh @o_turnbaug
14 Followers 3K FollowingDeonna Seymor @seymo_deonn
46 Followers 5K FollowingAdam🇺🇦 @WolfieTheAnt
137 Followers 1K Following Hockey (Leafs), InfoSec, Food, Travel, Health and Politics. opinions my own, retweets don’t equal an endorsement.MonzaMayhem @MayhemMonza
663 Followers 2K Following Mother of child with ME/CFS. Trying to create moments of joy in a challenging life.Jenny Anne Salsman @jennyAnneWren
150 Followers 1K Following Grad of Bloomsburg University's MSIT program. Dabbling in ID, development, and life.KarenG @tenacious_mumma
1K Followers 832 Following Mum/carer constantly fighting 4 health care 4 my beautiful daughter @spooniesophia bedbound with #lymedisease #severeME #POTS #chronicpain #allodynia #vertigoDr. Jennifer Curtin @jencurtinmd
3K Followers 2K Following Physician. Entrepreneur. Nerd. 🍊YCW22. RTHM co-founder. Recovered ME/CFS. Treated infection assoc illness b4 Covid. Tweets/DMs are my own & not medical advice.Chronically Illumise .. @ChronIllumise
22 Followers 239 Following Lily. #pwME, pwPOTS, Pokémon fan (she/her).P @coupdecoeur
141 Followers 482 FollowingThreeDShadow @moveablecube
174 Followers 708 Following Art, animals, nature, and learning. Never take your health for granted.Stefan K @ratio_verrueckt
191 Followers 206 FollowingZetixo @Zetixo
20 Followers 90 Followingsideshowbob zwoelf @sideshowbob12
16 Followers 133 Following laut verwandten und bekannten irgendwas mit computern - great and unmatched wisdom🦋Jacqueline Kohn W.. @jacqueline_kohn
471 Followers 5K Following All my life I have believed in "live and let live in peace." I no longer have the luxury of being passive. #TheResistance #MECFS #CeliacDisease Reiki MasterJasmina Daber @DaberJasm
50 Followers 5K FollowingJustin @justinmfnclark
6 Followers 61 FollowingHimmat @himmatb15
954 Followers 664 Following Writer and editor on pause due to Long Covid/vaccine injury since 2021. Severe and fully bedbound since 2023. ME/CFS | POTS | hEDS. he/him♡。.✰ 𝑺𝒕�.. @compassion_ate_
485 Followers 872 Following Sick 19yrs ✨Respect the Nuance✨#MECFS #Fibromyalgia #CKD #TBI #AFIB #Neurodivergent #Homelessness ⚽️🏄🏻♂️ 🎬🗣️✍🏼🇬🇷🇺🇸✡️ ✌🏼&💚🚫RACISM🚫zedsrigil @sunsweptforest
428 Followers 851 Following forest.haven they/them autistic me/cfs and more nature music outer spaceFranck Germain @CryptoChickO6
46 Followers 621 Following #VOLT MAXI (The Peoples Crypto) Get VOLTED or get left behind ⚡️⚡️⚡️ Let's shock the world together! https://t.co/7kFbTxBr3vGiannis Maragakis @Johannes_Mrgk
73 Followers 341 FollowingTa Lema @lema_ta38413
131 Followers 5K FollowingGottfried Weibler @goddyw567
1K Followers 4K Following Formerly CIO / Group IT Director, now on sabattical leave / retirement due to #MECFSC.H. Romatowski @CHRomatowski
505 Followers 792 Following Account used sporadically to engage with research. Tweets delete.Rebecca Ryan @DrRebeccaRyan
1K Followers 1K Following Gastroenterologist & Hepatologist. Disorders of the Gut Brain Axis. Treating Long Covid, POTS, MCAS and hEDS.#NotJustFatigue @njfatigue
579 Followers 653 Following We are a 501(c)(3) sounding the alarm on ME/CFS through digestible, creative content. This is #NotJustFatigueElizabeth Ansell @elizansell
682 Followers 2K Following Founder @njfatigue. Previously at Showtime and ABC News, among other places. Quit career due to #MECFS. This is #NotJustFatigue.Konstantinos Lontos @KonLontos
723 Followers 1K Following Hematologist @NovantHealth. Alumni @uoaofficial (MD), @PittTweet (PhD, IM/HemOnc) , @MDAndersonNews (BMT & CT). Fierce patient and environment advocateBen Frymer @bfrymer
986 Followers 5K Following Teach Liberal Studies/Sociology; education, film, philosophyNick Punt 🏕️ @nickpunt
2K Followers 2K Following Product creator / designer building your next book app. Interested in humane technologies. Background in psych, edtech, news, social, etc 🖤Annie 😍 @Annie7802
3 Followers 239 Following Advеnturous sрirit seeking а рartner fоr steаmy еnсоuntеrsBhupesh K Prusty @BhupeshPrusty
15K Followers 68 Following A passionate molecular virologist who believe in patient oriented scientific research. Using viruses to understand human existence. Science is for society.Hannah Davis @ahandvanish
60K Followers 4K Following Research, algorithmic music, machine learning/AI, anti-bias in AI data. #LongCovid research & advocacy @patientled. they/them. DMs rarely checkedChristoph Ströck @cstroeckw
7K Followers 455 Following Soon, people will look back in disbelief at what has happened to patients with #MECFS and #PAIS | @weandmecfs co-founderJonas R. Kunst (@kuns.. @KunstJonas
17K Followers 724 Following Professor of Psychology @UniOslo. Past @Yale @Harvard @UiB. Founder @Advances1n. Father. Views are my own. @kunstjonas.bsky.social @[email protected]LongCovidPharmD @organichemusic
37K Followers 1K Following Doctor of Pharmacy. Long Covid, EBV & ME/CFS research. Here to share & learn. Tweets not medical advice. https://t.co/jqc4g8cFLa https://t.co/lKQezPwtQsJanet Dafoe @JanetDafoe
15K Followers 220 Following Caregiver for very severe ME/CFS son, advocate and fundraiser for End ME/CFS PROJECT at OMF and CFSRC at Stanford. The rest of my life is on hold...Dr Claire Taylor @drclairetaylor
66K Followers 2K Following Doctor|Special interest in Long Covid,POTS,ME/CFS&MCAS| neuroscientist🧠Long Covid kids champion|WHN expert advisor|long Covid clinic🏴Views my ownIt'sME(Jaime) @exceedhergrasp1
20K Followers 5K Following Director of Sci & Med Outreach, #MEAction Stanford Med #ME, #EDS, #POTS, #LongCOVID Views my own [email protected]Prof. Akiko Iwasaki @VirusesImmunity
220K Followers 2K Following We study antiviral immunity and viral disease pathogenesis. #COVID19 #longCOVID #vaccines @HHMINEWS @YaleIBIO @YaleMed @YaleCII President of @ImmunologyAAIResia Pretorius @resiapretorius
27K Followers 218 Following Distinguished Prof: Physiological Sciences, Stellenbosch Univ, South Africa; Honorary prof: Univ of Liverpool Research: coagulation, inflammationAnil van der Zee © @AnilvanderZee
9K Followers 824 Following Former professional ballet dancer | Bed/sofa-bound M.E. patient | Using Twitter to raise awareness for #MyalgicE | #art2cureME #pwme #millionsmissingPutrino Lab @PutrinoLab
34K Followers 382 Following We make people (and technology) better at Mount Sinai. Opinions are my own.ME/CFS News @MECFSNews
15K Followers 712 Following News, interesting information and commentary on ME/CFS. My bluesky account is @mecfsnews.bsky.social Looking for paid ME/CFS related work.Dr Asad Khan FRCP FRA.. @doctorasadkhan
28K Followers 3K Following Lung Dr on pause since Nov 20 #LongCovid #POTS #MCAS #HSD #pwME #Aotearoa Views my own; Retweets≠endorsements #freepalestine #TeamClots ZIONISTS WILL BE BLOCKEDMartin Hippe @pausedME
7K Followers 474 Following East Westphalia by Nature ⎮Lawyer by Profession | #Musikrecht | #MECFS | @Mirame_Arts | No medical advice!Tom Kindlon @TomKindlon
14K Followers 578 Following With ME 35 years (29 yrs severe). 95% of posts on #MEcfs/#LongCovid/#chronicillness. 26 publications in peer-reviewed journals. @IrishMECFSAssoc trustee 27 yrsBilly Hanlon @bhanlon15
12K Followers 11K Following Director of Advocacy & Outreach, Minnesota ME/CFS Alliance | Long COVID AllyNaomi Harvey PhD #Wea.. @Naomi_D_Harvey
15K Followers 4K Following Zoologist. She/her. 22yrs with ME/CFS. Pro-vax but vaccine injured. Life on pause (views my own - unemployed) ♿️ https://t.co/YeMrEWwEg5Michael VanElzakker @MBVanElzakker
10K Followers 290 Following Neuroscience researcher @MGHMartinos / @HarvardMed and @PolyBioRF, researching #MEcfs, #LongCOVID, & #PTSD. (all opinions are my own)Tess Falor, Ph.D. | @.. @tessfalor
9K Followers 5K Following 🚀Space physicist➡️#MECFS researcher🧪 Founder - Renegade Research @renegaderes - RemissionBiome @remissionbiome ✨Serendipity Meets Preparation✨LongLonghauler @sketchingwitht
118 Followers 199 FollowingApril Dalaman⁷ @AprilDalaman
18K Followers 20K Following Always an angel, never a god. 💜 #FlowerPathPoet. @clapped3407
5 Followers 61 FollowingMiriam @miriamfrankmac
544 Followers 643 Following Comms. London. Coming back to life following Long Covid. Chasing peak health…UniteToFight2024 @U2Fight_World
3K Followers 121 Following 100% crowdfunded LC & ME/CFS conference project. community-driven. independent. global.Natasha 🐱🦠 @doyouseem_e_now
2K Followers 673 Following 29 & sick with Severe #LongCovid for 13 months 🛌 Part of the biggest mass disabling event in modern world history. #MillionsmissingJenny Anne Salsman @jennyAnneWren
150 Followers 1K Following Grad of Bloomsburg University's MSIT program. Dabbling in ID, development, and life.Molly Myers @mollistan
3K Followers 5K Following Woman=adult human female. Anti-woke but not indifferent to injustice. likes ev psych, free speech & debate, atheist, momx2, anti-zionist. politically homelessKONSTANTINOS GRIVAS @KONSTAN53401794
15K Followers 6K Following Καθηγητής Γεωπολιτικής και σύγχρονων στρατιωτικών τεχνολογιών, Στρατιωτική Σχολή Ευελπίδων.MonzaMayhem @MayhemMonza
663 Followers 2K Following Mother of child with ME/CFS. Trying to create moments of joy in a challenging life.KarenG @tenacious_mumma
1K Followers 832 Following Mum/carer constantly fighting 4 health care 4 my beautiful daughter @spooniesophia bedbound with #lymedisease #severeME #POTS #chronicpain #allodynia #vertigoDr. Jennifer Curtin @jencurtinmd
3K Followers 2K Following Physician. Entrepreneur. Nerd. 🍊YCW22. RTHM co-founder. Recovered ME/CFS. Treated infection assoc illness b4 Covid. Tweets/DMs are my own & not medical advice.MMitchell @mmitchell_ai
80K Followers 1K Following Interdisciplinary researcher focused on shaping AI towards long-term positive goals. ML & Ethics. Same content in the Sky, Threads, & the Prehistoric Elephantzedsrigil @sunsweptforest
428 Followers 851 Following forest.haven they/them autistic me/cfs and more nature music outer space♡。.✰ 𝑺𝒕�.. @compassion_ate_
485 Followers 872 Following Sick 19yrs ✨Respect the Nuance✨#MECFS #Fibromyalgia #CKD #TBI #AFIB #Neurodivergent #Homelessness ⚽️🏄🏻♂️ 🎬🗣️✍🏼🇬🇷🇺🇸✡️ ✌🏼&💚🚫RACISM🚫Himmat @himmatb15
954 Followers 664 Following Writer and editor on pause due to Long Covid/vaccine injury since 2021. Severe and fully bedbound since 2023. ME/CFS | POTS | hEDS. he/himFranck Germain @CryptoChickO6
46 Followers 621 Following #VOLT MAXI (The Peoples Crypto) Get VOLTED or get left behind ⚡️⚡️⚡️ Let's shock the world together! https://t.co/7kFbTxBr3vGiannis Maragakis @Johannes_Mrgk
73 Followers 341 FollowingBryan Jasker PT, DPT @oval_MetFlex
501 Followers 3K Following CCO at OVAL | NUPTHMS | Metabolic Fitness | Metabolic Flexibility | Lactate | Mitochondria | Health AdditiveGottfried Weibler @goddyw567
1K Followers 4K Following Formerly CIO / Group IT Director, now on sabattical leave / retirement due to #MECFSC.H. Romatowski @CHRomatowski
505 Followers 792 Following Account used sporadically to engage with research. Tweets delete.Elizabeth Ansell @elizansell
682 Followers 2K Following Founder @njfatigue. Previously at Showtime and ABC News, among other places. Quit career due to #MECFS. This is #NotJustFatigue.#NotJustFatigue @njfatigue
579 Followers 653 Following We are a 501(c)(3) sounding the alarm on ME/CFS through digestible, creative content. This is #NotJustFatigueRebecca Ryan @DrRebeccaRyan
1K Followers 1K Following Gastroenterologist & Hepatologist. Disorders of the Gut Brain Axis. Treating Long Covid, POTS, MCAS and hEDS.Konstantinos Lontos @KonLontos
723 Followers 1K Following Hematologist @NovantHealth. Alumni @uoaofficial (MD), @PittTweet (PhD, IM/HemOnc) , @MDAndersonNews (BMT & CT). Fierce patient and environment advocateBen Frymer @bfrymer
986 Followers 5K Following Teach Liberal Studies/Sociology; education, film, philosophyNick Punt 🏕️ @nickpunt
2K Followers 2K Following Product creator / designer building your next book app. Interested in humane technologies. Background in psych, edtech, news, social, etc 🖤Jenny K 🌿🌳🌍 @Knitty19
586 Followers 1K Following Parent. Nature lover. Standing up for trees. Not flying anywhere. Car free. Knitter. Degrowth. Green Party member. Dysautonomia.Amanda Crist @ZebraLoveCo
214 Followers 442 Following Writing about #hEDS 🦓, #muscle, health☕️, genetics, and how I’m trying to walk again🌱 #bedbound #homebound #calfproblems #zoologyFigure @Figure_robot
72K Followers 1 Following Figure is an AI Robotics company building the world's first commercially viable autonomous humanoid robot.Brett Adcock @adcock_brett
172K Followers 14 Following Founder @Figure_robot (AI Robotics) & Archer Aviation (NYSE: ACHR)Ralser Lab @RalserLab
3K Followers 824 FollowingEleni @eleni_nyc_
163 Followers 718 Following Here for the latest science, medical updates & support 🧪 🧬 😷 💊 🦠 LC deniers, minimisers & trolls=blocked & flagged (flogged would be more appropriate)Debbie Filippaki, BSW.. @filippakid
814 Followers 2K Following Teacher & social worker: environmental & health humanities, community development, linguistics, queer & disability pride. Workplace violence survivor.Pat Casola @p_casola
47 Followers 564 FollowingMichael Gleeson @Carnageincoming
50 Followers 169 FollowingNatalia @NataliaHodgins
7K Followers 1K Following Disabled writer with words in @Refinery29AU, @ABCNews, @PublicHerald | Activist | Feminist | MECFS | Follow on IG - same handleChryss Terry @ChryssTerry
111 Followers 541 FollowingSeren Morgan Jones @SerenMJones
619 Followers 1K Following Artist✨instagram: serenmorganjones ✨[email protected]✨ for prints check insta or DM. Diolch thanksDee @po_move
2K Followers 2K Following Mental health, inequality & disability. Long covid research & treatment. #LongCovid #MCAS #POTS #MECFS #vaccineinjuries #FBLCDasIstME @BobundDaisy
1K Followers 2K Following Psychologin, bis 2016 spez. in Therapien bei #ASS, seither arbeitsunfähig aufgrund ME, seit Covid schwer erkrankt #MECFS #LongCovidGurki Gurkmeister �.. @Ausversehen999
383 Followers 2K FollowingAmy @alexandrite113
6K Followers 844 Following Long Covid to very severe ME/CFS to mod/severe ME/CFS. Tweeting into the void. DX'd autistic ✨Ted Donnelly @fequalsma6280
688 Followers 3K Followinglongcovidactivism @laubelgium
206 Followers 428 FollowingJoseph Marquis @josephpmarquis
2K Followers 2K Following Itinerant teacher supporting students with diverse learning needs. Tweets are my own.Jody Weymouth 🇺�.. @JodyWeymouth
476 Followers 732 Following Photographer, avid reader, army wife, mom to 2 rescue dogs@ValeBodi @lifeanalytics - Have you seen this paper?
@lifeanalytics Looking forward to see what's working for you!
@lifeanalytics Themos, does it have anything to do with glutamine, glutamate, and gaba?
@U2Fight_World Re Speakers: Maybe you want also ask @Aguirre1Gustavo, he treats his #LongCovid patients? And @lifeanalytics? And @oslersweb? History is important to make right conclusions. They know a lot about #MyalgicE and LC. We need treatments, nothing else.
A bigger picture could be emerging #longcovid #MECFS #gulfwarillness and likely others #Lyme #MCAS #MCS
1/ This is a thread for the study (preprint) by @C_Scheibenbogen et. al named "Role of the complement system in LongCOVID" and the use of certain analytical techniques for interpretation of its results. Tagging @RenzPolster @fereshtehjahan1 @mhornig @cstroeckw
@lifeanalytics The potential role of IgE in ME/CFS has been extensively discussed in our recent publication. frontiersin.org/journals/immun…
@lifeanalytics @C_Scheibenbogen @RenzPolster @mhornig @cstroeckw I look forward to more research in this field.
@lifeanalytics @C_Scheibenbogen @RenzPolster @mhornig @cstroeckw Thank you for sharing this great work. Based on my observation, dysregulation in complement and coagulation is more widespread in LC due to spike protein interferes with the RAAS system. However, in ME/CFS, a subset shows significant abnormalities in the complement cascade.
@lifeanalytics These data suggest that TUDCA may be beneficial in treating neurodegenerative disorders in which increased glutamate levels contribute to the pathogenesis of the disease. jpet.aspetjournals.org/content/311/2/…
@lifeanalytics Taurine reduces glutamate-induced elevation of calcium by inhibiting its influx from various calcium channels including the reverse mode of Na+/Ca2+ exchanger,..., and glutamate NMDA receptors. jbiomedsci.biomedcentral.com/articles/10.11….
Even drug and supplement toxicity can play a role as triggers! That is why I believe running a big cohort longitudinal multi-omics study is a necessity to understand ME/CFS and its major comorbidities such as hEDS/HSD, post-treatment Lyme disease, PANS, etc.
I couldn't agree more! ME/CFS can be caused by a combination of genetic and environmental risk factors of any sort. Sometimes, a profound environmental risk factor could be sufficient, and in some cases, it could be a late-onset manifestation of an inherited condition!
We have to keep in mind that there are other potential triggers of #MECFS apart from viral infections. Organophosphates may be one of them. Glutamate, cholinergic signaling and the role of benzodiazepines (cc @fereshtehjahan1 ) : pubmed.ncbi.nlm.nih.gov/15521192/
@lifeanalytics @jenbrea I think you are providing the leads to crack this problem, and not enough people are paying attention. Some day, Themos, I will be the first to point to you as having called this way back when. 🙏
@arta_semita @KatBoniface @miguelcasali @joshual_tm @lifeanalytics
@doc4care @IsabelRamirezRD @tessfalor @CiaraGlenville @renesugar Seems recently discovered so not heaps of data on it, but this surely should be on the list for trials with ME & LC nature.com/articles/s4159…
Non antibiotic drugs that kill bacteria, thus altering the microbiome - @lifeanalytics sciencealert.com/machine-learni…
@lifeanalytics Sometimes in benzo and SSRI protracted withdrawal.
@lifeanalytics Wait what? Post-accutane syndrome presents like MECFS too? I had years of accutane as a teenager 😭
@lifeanalytics "POST TREATMENT" says it all.
So encouraging to see our recent paper has "more views than 80% of all Frontiers articles." It simply highlights the need to delve deeper into ME/CFS, EDS/hEDS/HSD, MCAS, POTS, Lyme, Dysautonomia, and Long COVID to help a diverse group of patients with comorbidities.#MECFS