Charles Brenner, PhD @CharlesMBrenner
NAD metabolism / quantitative mass spec / Fatty liver, diabesity & cancer / Dept Chair @CityofHope / Truth in science / Tweets are mine alone brennerlab.net Los Angeles Joined May 2018-
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.@davidasinclair "my lab’s ideas & findings are typically ahead of the curve, which is why some peers might feel the research is overstated at the time" no actually, the dog pills didn't outperform the placebo & you are a professional obfuscator wsj.com/health/wellnes…
hoping this is a parody account
example 409 that age tests don’t measure what ppl think they are measuring
It pains me to see facile critiques of GWAS on here from our clinical/biostats friends while the many actually good reasons to be critical of GWAS get little attention. So here's a thread on what GWAS does, what critics get wrong, and where GWAS is genuinely still lacking. 🧵:
Happy 91st birthday Willie Nelson! Big thanks to you and Annie for your support, confidence in science, and inspiration. Keep on rocking and inspiring us all! @UTSWMedCenter @BioAnnie2 @WillieNelson
stretching is great but the study doesn’t show that stretching reduces all cause mortality like most of the sauna studies, this is an association result essentially showing that ppl who do yoga have lower death rates see the problem here?
stretching is great but the study doesn’t show that stretching reduces all cause mortality like most of the sauna studies, this is an association result essentially showing that ppl who do yoga have lower death rates see the problem here?
if you are looking for your newspaper to always confirm your priors, you are doing it wrong
Life Metabolism is 2 years old. Come and follow us @lifemetabolism2 and also consider sending us your interesting papers on anything related to metabolism. While you are considering, remember we have no page charges.
Life Metabolism is 2 years old. Come and follow us @lifemetabolism2 and also consider sending us your interesting papers on anything related to metabolism. While you are considering, remember we have no page charges.
@EricTopol @CharlesMBrenner @NirBarzilaiMD @wysscoray @ahlresearch @DBelardoMD @mkaeberlein @dillinlab Kudos on being among one of the first to call Sinclair out
"Preying on very vulnerable people" "The pushback against how Sinclair portrays his work reflects a conviction that a field once considered fringe is gaining legitimacy." wsj.com/health/wellnes… @NirBarzilaiMD @wysscoray @ahlresearch @DBelardoMD @mkaeberlein @dillinlab
@CharlesMBrenner would have plenty to add on this topic! Longevity has become a scam.
@CharlesMBrenner would have plenty to add on this topic! Longevity has become a scam.
Congratulations to Jianjun Chen, Ph.D., chair of the Department of Systems Biology and deputy director of the Center for RNA Biology and Therapeutics! #AAASFellows
Congratulations to Jianjun Chen, Ph.D., chair of the Department of Systems Biology and deputy director of the Center for RNA Biology and Therapeutics! #AAASFellows
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example 409 that age tests don’t measure what ppl think they are measuring
Unveiling the Rockstars of Aging Research: Who to Follow for a Longer, Healthier You! 🫵 Ever dreamt of living a long and healthy life? 🧵1/16
@aubreydegrey @ProfValterLongo @EricVerdin @statto @vita_dao @NirBarzilaiMD 7. @CharlesMBrenner: A researcher on NAD metabolism and healthy skeptic on aging research. 🧵9/16
"How can this be happening? You do so much yoga." nerdfighteria.info/v/734251282/
stretching is great but the study doesn’t show that stretching reduces all cause mortality like most of the sauna studies, this is an association result essentially showing that ppl who do yoga have lower death rates see the problem here?
Found a curious paper that claims that most epigenetic clocks have a built-in circadian rhythm, showing the lowest biological age at midnight and the highest at noon, with a difference of up to several years within a day for the same person 😬 The study is extremely small, so…
Had so much fun with my family walking around the Met. We were really awestruck by the Cycladian art today, e.g. this guy from 5000 years ago
It pains me to see facile critiques of GWAS on here from our clinical/biostats friends while the many actually good reasons to be critical of GWAS get little attention. So here's a thread on what GWAS does, what critics get wrong, and where GWAS is genuinely still lacking. 🧵:
Happy 91st birthday Willie Nelson! Big thanks to you and Annie for your support, confidence in science, and inspiration. Keep on rocking and inspiring us all! @UTSWMedCenter @BioAnnie2 @WillieNelson
Venki Ramakrishnan on aging-focused companies: “Many of these companies have highly distinguished scientists on their advisory boards - including some Nobel laureates who have no particular expertise in aging, apart from being old.”
An untaught but important rule for thriving in academia is ‘strategic synergy’ (or ‘two birds with one stone’). Need to give a talk on something? Use it as a practice for another presentation. Need to write a grant progress report? Use it as a draft for a review you are writing.
@theproof @Lipoprotein @realDaveFeldman That is a cock-a-mammie theory with ZERO proof. Amazing how folks with zero lipid education just use the internet, not seriously peer-reviewed journals to invent theories. If there was more TG production both VLDL-P, especially VLDL size and serum TG would go up. They would need…
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@EricTopol @CharlesMBrenner @NirBarzilaiMD @wysscoray @ahlresearch @DBelardoMD @mkaeberlein @dillinlab Kudos on being among one of the first to call Sinclair out
@CharlesMBrenner @ScienceMagazine @StevenAustad I'm in total agreement with you! 💪🏻🫀🩺
"Preying on very vulnerable people" "The pushback against how Sinclair portrays his work reflects a conviction that a field once considered fringe is gaining legitimacy." wsj.com/health/wellnes… @NirBarzilaiMD @wysscoray @ahlresearch @DBelardoMD @mkaeberlein @dillinlab
@0xSCSamurai Agree. It's called natural selection.
@CharlesMBrenner would have plenty to add on this topic! Longevity has become a scam.
"Preying on very vulnerable people" "The pushback against how Sinclair portrays his work reflects a conviction that a field once considered fringe is gaining legitimacy." wsj.com/health/wellnes… @NirBarzilaiMD @wysscoray @ahlresearch @DBelardoMD @mkaeberlein @dillinlab
Congratulations to Jianjun Chen, Ph.D., chair of the Department of Systems Biology and deputy director of the Center for RNA Biology and Therapeutics! #AAASFellows
AAAS is thrilled to announce our 2023 #AAASFellows! “This year’s class embodies scientific excellence, fosters trust in science throughout the communities they serve, and leads the next generation of scientists,” said AAAS CEO @sudipsparikh. Read more: brnw.ch/21wIWyv
Inspired by his sister's battle with childhood leukemia, Saro Armenian, D.O., M.P.H. has dedicated his life to treating young people with cancer. Read more on his impactful career in pediatric cancer treatment and research. bit.ly/3Q2UlsQ