Aging Science News @AgingBiology
Latest news in the biology and genetics of aging, covering longevity science, rejuvenation technologies and life-extension research. Tweets by @jpsenescence senescence.info Joined November 2013-
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Immunological aspects of central neurodegeneration nature.com/articles/s4142…
Normal or improved cardiovascular risk factors in IGF-I-deficient adults with growth hormone receptor deficiency cell.com/med/abstract/S…
Neuronal cell cycle reentry events in the aging brain are more prevalent in neurodegeneration and lead to cellular senescence journals.plos.org/plosbiology/ar…
SuperAgers and centenarians, dynamics of healthy ageing with cognitive resilience sciencedirect.com/science/articl…
Multimodal cell atlas of the ageing human skeletal muscle nature.com/articles/s4158…
A disease similarity approach identifies short-lived Niemann-Pick type C disease mice with accelerated brain aging as a novel mouse model for Alzheimer's disease and aging research biorxiv.org/content/10.110…
The senescence-associated secretory phenotype and its physiological and pathological implications nature.com/articles/s4158…
DNA methylation-based telomere length is associated with HIV infection, physical frailty, cancer, and all-cause mortality onlinelibrary.wiley.com/doi/full/10.11…
NMR metabolomic modeling of age and lifespan: A multicohort analysis onlinelibrary.wiley.com/doi/full/10.11…
A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence elifesciences.org/articles/87811
Gene Therapy for Skin Aging eurekaselect.com/article/139359
Epigenetic age oscillates during the day onlinelibrary.wiley.com/doi/10.1111/ac…
Dietary restriction extends lifespan across different temperatures in the fly besjournals.onlinelibrary.wiley.com/doi/full/10.11…
Life history trade-offs in Drosophila: flies select a diet to maximize reproduction at the expense of lifespan academic.oup.com/biomedgerontol…
Evolution of T cells in the cancer-resistant naked mole-rat nature.com/articles/s4146…
pyaging: a Python-based compendium of GPU-optimized aging clocks academic.oup.com/bioinformatics…
Partial Cell Reprogramming as a Way to Revitalize Living Systems link.springer.com/article/10.113…
Genetic Correlates of Biological Aging and the Influence on Prediction of Mortality academic.oup.com/biomedgerontol…
Aging as a loss of morphostatic information: a developmental bioelectricity perspective sciencedirect.com/science/articl…
Fasting mimicking diet extends lifespan and improves intestinal and cognitive health pubs.rsc.org/en/content/art…
David Sinclair @davidasinclair
442K Followers 1K Following Professor, Scientist. Mission: Extend healthy life for all. Views & analyses are my own.
Agingdoc⭐David Barz.. @agingdoc1
31K Followers 100 Following Health & longevity coaching at:👉https://t.co/XWGLGiSPyZ Longevity, health, aging, diet, exercise, evidence, healthspan, lifespan, rapamycin, geroscience🚫advice⚕️
João Pedro de Magalh.. @jpsenescence
15K Followers 2K Following Scientist planning to live forever (so far so good!), professor decoding the genome @unibirmingham, geek, entrepreneur, speaker, writer, keen footballer.
Björn Schumacher @schumacherbj
17K Followers 2K Following I'm a scientist 👨⚕️, author 📕and chair for genome stability in aging and disease at the University of Cologne
Morgan Levine @DrMorganLevine
18K Followers 444 Following Founding PI at Altos Labs | Former Professor at Yale | Thoughts and opinions are my own
Nathan S. Cheng think.. @realNathanCheng
12K Followers 649 Following Mission: Moonshot to end aging. Director, Longevity Biotech Fellowship / https://t.co/XIKhk2FDDd, https://t.co/ZGc47xuFt9, GP @healthspancap
Brunet Lab @BrunetLab
10K Followers 5K Following Aging lab @Stanford - Epigenomics and metabolism in #aging; Brain aging and rejuvenation; Neural stem cells; C. elegans; African #killifish
Longevity Technology @LongevityTech
11K Followers 2K Following Daily news and insights on research, investments and technologies that extend life and improve the quality of that extended life. #Longevity
Buck Institute @BuckInstitute
16K Followers 1K Following Our mission is to end the threat of age-related disease for this and future generations
Andrew Steele @statto
11K Followers 3K Following Scientist (physicist-turned-biologist) / Writer (https://t.co/b7cDbmWGKN) / Presenter (https://t.co/ChpWwP9GqY) / Campaigner / Mastodon, Bluesky, etc: https://t.co/3sPVSia1eE
FrezzaLab @FrezzaLab
25K Followers 3K Following We are a group of metabolism-lovers, focused on mitochondrial metabolism. Tweets are from Christian. https://t.co/EbWsJo6DnZ
Nir Barzilai @NirBarzilaiMD
9K Followers 125 Following Prof. of Medicine & Genetics @EinsteinMed | Scientific Director @AFARorg | Director @EinsteinAging | Leading the TAME trial | Opinions mostly on aging science
Bérénice A. Benayou.. @BBParis1984
3K Followers 2K Following Associate professor @USC Gero. French scientist. Aging, omics, immunity, sex-dimorphism. Views my own. She/her.
Yuri Deigin @ydeigin
26K Followers 1K Following Drug developer of Alzheimer’s/CNS gene therapies https://t.co/HPgKP0qGJv | Vitalist & longevity maximalist | DRASTIC cofounder https://t.co/jpRBlDRMg1 |🇺🇦🇨🇦
Martin Borch Jensen @MartinBJensen
6K Followers 474 Following Aging, Systems Biology, Gene Therapy. CSO @GordianBio, doing pooled therapeutic screens in vivo. Also @impetusgrants, https://t.co/KWEUni9245. Prev K99 Fellow @BuckInstitute
Matt Yousefzadeh @MattYousefzadeh
4K Followers 4K Following Scientist studying aging at Columbia University. @CCTI_NYC
Cell Metabolism @Cell_Metabolism
47K Followers 477 Following Cell Press journal publishing cutting-edge research in metabolism biology, from molecular/cellular biology to translational and clinical studies.
Shahaf Peleg 🌅 @DocLarus
2K Followers 2K Following Tenured PI at FBN. Co-founder of Luminova Biotech. Working on Light and energy replacement. Into anti-aging. Amateur ♟ LoL = L of Light
Pankaj kapahi @kapahi_pankaj
2K Followers 1K Following Professor at Buck Institute & UCSF | senior editor E-life | antagonistic pleiotropy, dietary restriction, TOR, glycation, aging, senescence
BrainBodyBalance @bbb_journey
0 Followers 39 Following Research-backed tips on mindset, fitness, nutrition, productivity & wellbeing. Join the #BBB journey!
Ufoloji Türkiye @Ufolojiturkiye
2 Followers 46 Following 🌌 Bilimsel yaklaşımlarla uzay ve UFO fenomenlerini araştıran resmi hesap. Evrenin sonsuzluğunda sizi bilgiyle buluşturuyoruz! 🛸🔭
ramón lavandera @GuamutasRamon
434 Followers 3K Following
Drsergiocolagrande @drcolagrande
208 Followers 781 Following Nutrologia, Medicina Integrativa, Esportiva e do Estilo de Vida. Longevidade saudável, Ortomolecular. Prevenção e tratamento de doenças crônicas e autoimune.
Lion7575 @Lion75751
61 Followers 308 Following
Dr Tim Pearce @drtimpearce
200 Followers 165 Following I help medical aesthetic practitioners overcome the obstacles to become safe, effective and successful.
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16 Followers 188 Following
Suiliang Xia @YanYang80603102
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Anson @Anson41598899
260 Followers 2K Following
Shelley Buffenstein @ShelleyBuffens1
158 Followers 335 Following
Lina Rose @LinaSpringRose
132 Followers 2K Following she/they pronouns, I am heteroromantic asexual demigirl and also a aegosexual yumejoshi
DNAmic BioSystems @DnamicBio
5 Followers 23 Following Creating advanced bioengineering systems to reverse aging and repair tissue damage directly within the body.
Henry @Enrique56862666
264 Followers 870 Following
Hariom Yadav @YadavHariom_Sci
216 Followers 374 Following Director of USF Center for Microbiome Research, Associate Professor of Neurosurgery and Brain Repair, University of South Florida
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0 Followers 15 Following
MANZI Ndamukunze @MNdamukunze
432 Followers 3K Following Renforcement des Capacités - AT en finance inclusive (capacity building-TA in i.f.) Engaged for Persons Living with a Rare Disease (PLWRD) with CENTRE-ALLIANCE
Ty Loomis @tyroneloomis
1K Followers 2K Following 🏆@AVPBeach Volleyball Champ & 18-Year Pro 💙 Blockchain, Consciousness, Intelligence, Health, Humanity, Longevity, Wellness, Truth & Solutions 💙 My ENS Sale👇
Mateusz Starus @Mateusz08370982
112 Followers 831 Following
O.G. Duddy @Derry_Man1
616 Followers 1K Following I am a foodie, an engineer, a culture vulture, a technologist, a political anorak, autistic and a general messer. Opinions expressed are my own.
Christos Mavrommatis @ChristosMaSc
6 Followers 118 Following Postgraduate Research Student @EdinburghUni. BSc Medical Genetics @uniofleicester. Ageing Research Enthusiast / Aspiring Scientist .
Carlos Maciel @C4rlosMaci3l
17 Followers 471 Following
Кекенавт Во.. @SibWojciech
3K Followers 1K Following Тип историк, тип программист, амбассадор TNO шуе: 'Сталинист, нацист, коми, либераха, Гитлер, лахта'. (Все перечисленное осуждаюи формирую негативное отношение)
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7 Followers 24 Following
TomRiddle @TomRiddle137
1 Followers 40 Following
Jonathan @revganger
30 Followers 496 Following
Emy @catsarecats21
0 Followers 8 Following
Rachid Mounir @RachidM38804100
22 Followers 475 Following
LeBron Fans 👑 @LeBronJames
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James Mulcahy @jamesmulcahyiii
137 Followers 274 Following
BTOB💙Wind&Wish&�.. @jjjiiiinnnnnn
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Oluwatoyin abifarin @Oluwatoyin16758
2 Followers 44 Following
Yiyang @YiyangGuo2
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Moutushi Islam (モ�.. @MoutushiIslam1
186 Followers 358 Following PhD student(Kanemaki Lab), National Institute of Genetics,Japan.@NIG_idenken MEXT scholar🎖@mextjapan
KeishoHASE @KeishoHASE
407 Followers 834 Following 🇸🇬/hby/Keio Pha 若返り研究 wellbeing AgriTech Nucleate Japan 基本情報技術者, Wit KBC entrepreneurship, 中小企業診断士（一次合格） 日本を再び世界の価値を創造する世界一の国に~Japan as No.1 Again~
Carlos @carlosrodrigolr
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Laércio Barros #LIFE.. @LaercioBarross
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WL@0 @Wl2021b
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Verena Straub @VerenaStraub
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João Pedro de Magalh.. @jpsenescence
15K Followers 2K Following Scientist planning to live forever (so far so good!), professor decoding the genome @unibirmingham, geek, entrepreneur, speaker, writer, keen footballer.
We're looking forward to hearing from @jpsenescence from @unibirmingham and his innovative systems approaches to better understand ageing at #BSRA2024 🗓️4th - 6th September 🔗bsra.org.uk/events/bsra-an…
Live footage of Nature editor at work
#PaperSpotlight: New study by researchers Gabriel Arantes dos Santos, Gustavo Daniel Vega Magdaleno & João Pedro de Magalhães (@jpsenescence) from @usponline @unibirmingham & @LivUni: “Evidence of a pan-tissue decline in stemness during human aging” DOI: doi.org/10.18632/aging…
Fantastic to participate in a debate on aging at the historic (founded in 1815) and stunning Cambridge Union Society.
Did dinosaurs impact how today’s mammals age? New research proposes a hypothesis that suggests dinosaurs played an important role in shaping the aging rate of present-day mammals. @jpsenescence #innovation #dinosaurs #aging #longevitybottleneck longevity.technology/news/did-dinos…
New study of miRNA expression in muscle aging and caloric restriction in rats Upregulated miRNAs with age linked to downregulated proteins in muscle development, metabolism, and longevity pathways 1/3 biorxiv.org/content/10.110…
We are excited to announce scientist, futurist and entrepreneur @jpsenescence as our guest for April 12th. Come and join us @inTheWarehouse or online via Zoom. Members £3, non-members £6 / Zoom attendance free for members, £3.15 non-members - book at eventbrite.co.uk/e/878769602537
Excited our paper showing a pan-tissue decline in stemness during human aging is now out! 🚨 Using transcriptome data and a machine learning methodology we show that stemness declines with age in most human tissues. aging-us.com/article/205717…
Wow, fascinating discovery that some RNAs in mice last for >2 years. These RNAs were observed in particular neural cell types and are important for chromatin maintenance and cell plasticity. Could the stability of some RNAs be important in aging? science.org/doi/10.1126/sc…
@SsJankauskas @Nature Agree 💯 and, in fact, we make similar arguments in our recent paper: sciencedirect.com/science/articl…
My problem here is that if a marker of aging changes with pregnancy then my interpretation is not that pregnancy accelerates aging but rather that the marker of aging is not actually measuring aging. If anything this questions the reliability of epigenetic markers of aging.
Pregnancy advances your ‘biological’ age — but giving birth turns it back nature.com/articles/d4158…
Interesting article @Telegraph on how lifestyle habits can impact anti-ageing genes to improve health and potentially allow us to live longer. It covers caloric restriction, exercise, nutrition and longevity drugs, including my thoughts. telegraph.co.uk/health-fitness…
A lovely tribute to Judy Campisi @CellCellPress by @EricVerdin @BuckInstitute "I think the most important part of science is being prepared to be wrong." - Judith Campisi
Judith Campisi (1948–2024) cell.com/cell/fulltext/…
New paper on DNA sequencing, inherited mutations, and the role of somatic mutations in ageing. We argue that, with a few exceptions like cancer, recent studies do not support the idea that somatic mutations drive human ageing phenotypes. 1/2 sciencedirect.com/science/articl…
New preprint from our lab on transcriptome analysis of muscle aging in rats. Massive work by PhD student Gulam Altab showing changes with age in protein folding, immune responses, and developmental genes. Also studied the effects of caloric restriction. biorxiv.org/content/10.110…
Join us this Thursday, March 14, for a seminar from @gwei_sha on @vita_dao and Longevity Biotech investments. The seminar will take place at 1pm in WF38 of the Medical School @unibirmingham Please message/email me if interested in attending.
Interesting clinical trial of senolytics that failed to reduce epigenetic age. Senolytic treatment might even accelerate epigenetic age, and they observed changes in immune cell proportions. It's a small study (n = 19) lasting 6 months, so larger, longer studies are needed.
Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions aging-us.com/article/205581…
On #WorldBookDay I have been reading this book by Bill Bryson. One key takeaway is that many scientists make a major discovery yet are forgotten because they didn’t publish quickly, couldn’t express their ideas clearly or another (more famous) scientist took credit for it.
Gentle reminder that no matter how young, healthy, rich and powerful you are now, you will inevitably age, degenerate and die. Let's solve aging!
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