D.Polychronopoulos @dpolychr2
Director, In Silico Biology @OchreBio; Ex @AstraZeneca @GenomicsEngland @imperialcollege @NCSR_Demokritos; Views my own; RT != endorsement dpolychr.github.io Oxford, United Kingdom Joined May 2016-
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What I’m reading this week in single cell omics, generative AI in genomics and medicine, microbial genomics, bioinformatics software, … 🧬🖥️🧵
How to link single-cell diversity and the emergence and maintenance of robust multicellular processes in developed tissues? 🤔 What can we learn about multicellular coordination in tissues from single-cell omics data? Read about our view: arxiv.org/abs/2403.06753
Opportunities and tradeoffs in single-cell transcriptomic technologies buff.ly/47NcBgv
With six approved drugs, siRNA is now an established therapeutic modality poised for expansion go.nature.com/49tcrf8 rdcu.be/dAsb2
**Is single-cell data integration a solved problem? ** Lots of great methods, but still not quite yet! Specifically, Check Dataset Imbalance! 🎉 Excited to announce that our study on dataset imbalances in single-cell analysis just hit Nature Biotechnology (@NatureBiotech)! 🎉…
Are you looking to apply Large Language Models to biomedical questions? You may want to take a look at our new framework (biochatter.org) and the updated preprint (arxiv.org/abs/2305.06488). 🧵👇
Major Cell2Sentence update 🎉🔬! We’ve been thrilled to see the attention Cell2Sentence has received from the single-cell community. Now, we’re excited to release our first update of Cell2Sentence (C2S) - a framework to leverage LLMs to train foundational single-cell models,…
Our 🪐SATURN method is now out in @naturemethods! SATURN paves the way for universal cell embeddings, enabling integration of datasets across different species 🐒🐁🧍🐟🐸 Using protein language models, we encode biological meaning of genes in scRNA-seq datasets.
Our 🪐SATURN method is now out in @naturemethods! SATURN paves the way for universal cell embeddings, enabling integration of datasets across different species 🐒🐁🧍🐟🐸 Using protein language models, we encode biological meaning of genes in scRNA-seq datasets.
Using Human Protein Atlas to Find Tissue Specific Genes in R using bioconductor buff.ly/3OK6DpH #rstats
In October ‘23, @stateofaireport reached its 5th anniversary. With 934 slides over 6 editions serving as a historical document, we’re opening 2024 with a retrospective of the main storylines, what we predicted, and what we didn't. Welcome to the State of the State of AI. 🧵
🔬Is the future of liver therapies better #AI or better #data? In a conversation with @PharmaTimes, our CSO & co-founder @QuinWills talked about the urgent challenge of #LiverDisease and our world-first ‘liver ICU’. Read now (page 32) ⬇️ magazine.pharmatimes.com/#/reader/50929…
"The average R&D efficiency of big pharma was $6.16 billion total R&D expenditures per new drug." 😱 And remember, that's the average, meaning ~half are higher than that! @ideapharma $XBI sciencedirect.com/science/articl…
Gene panel selection for targeted spatial transcriptomics | Genome Biology | Full Text genomebiology.biomedcentral.com/articles/10.11…
🎉 Thrilled to announce the very first 2024 preprint from our lab: U-Mamba 🐍, a novel backbone for universal bio-medical image segmentation! Background: Transformers have not transformed bio-medical images. While Transformers excel in general vision and language tasks, they…
Introducing PDGrapher - Combinatorial prediction of therapeutically useful chemical and genetic perturbations using causally-inspired neural networks Many methods learn responses to perturbations, but PDGrapher is addressing the inverse problem, which is to infer the perturbagen…
Excited to share iStar, which was just published in @NatureBiotech By leveraging high-resolution histology image information, iStar can increase the spatial resolution of sequencing-based ST platform such as Visium @10xGenomics to near single-cell level. x.com/naturebiotech/…
Excited to share iStar, which was just published in @NatureBiotech By leveraging high-resolution histology image information, iStar can increase the spatial resolution of sequencing-based ST platform such as Visium @10xGenomics to near single-cell level. x.com/naturebiotech/…
Any #rstats-ers have learning python in their 2024 resolutions? Learning a new language, it's hard to abandon the workflow you know and love. In my last post of 2023, I recommend some of the latest python pkgs/versions with similar ergonomics 🧵1/n emilyriederer.com/post/py-rgo/
The Exploding Generative AI Market bain.com/insights/explo…
Algorithm for optimized mRNA design improves stability and immunogenicity buff.ly/44AvQZV
This was a much needed answer to an important question emerging from Hi-C-type studies, seeing promoters coming together in 3D space. Well done, @Eileen_Furlong team!
This was a much needed answer to an important question emerging from Hi-C-type studies, seeing promoters coming together in 3D space. Well done, @Eileen_Furlong team!
Manolis Kellis @manoliskellis
25K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute
Veera Rajagopal @doctorveera
17K Followers 4K Following MBBS, MD, PhD | GWAS storyteller | Scientist at Regeneron | Human genetics & drug discovery in Neuroscience & Psychiatry | He/Him
Akis Papantonis @AkisPapantonis
3K Followers 1K Following Professor for Translational Epigenetics, University Medical Centre Goettingen, University of Goettingen, DE …oftentimes aspiring fiction writer.
Evangelia Petsalaki @e_petsalaki
2K Followers 577 Following Group Leader at EMBL-EBI, interested in context specific regulation of human cell signalling. Mastodon: @[email protected]
Antoine Hocher @antoine_hocher
465 Followers 648 Following Systems biology and evolution of chromatin Post-doc in the Molecular Systems Laboratory, MRC-LMS Incoming group leader, Genetics Dept, University of Cambridge
Helena Cocheme @CochemeLab
890 Followers 1K Following Group Head @MRC_LMS @ImperialCollege Lab studying #redox signalling, metabolism, diets and #ageing in #Drosophila
Florian Markowetz @markowetzlab
4K Followers 2K Following Computational Oncology at Cambridge | chromosomal instability | genomes and images | selfish about reproducibility | all fox, no hedgehog
Christoforos Nikolaou @guilderstern
1K Followers 671 Following Computational Biologist, Researcher at @BSRC_Fleming, author and amateur sports journalist. "What difference can you make, a single man in all this madness?"
Alejandro Montenegro @aemonten
9K Followers 7K Following Molecular Biologist, PhD丨Chief Editor CSH Protocols & Head of Integrity in Publishing — @CSHL丨Scientific Chair @molbiosystems丨Central Dogma Police丨Chilean 🇨🇱
เกษิดา @7EKn6L64vMU55M
51 Followers 1K Following คุณต้องการนัดเดทกับสาวไหมคะ เพิ่ม https://t.co/qM8w4JQWXT
Lilianna Tok @LiliannaT99397
58 Followers 5K Following
Katherine Popwell @PopweKatherin
70 Followers 5K Following
Phoebe Kounthapanya @PhoebeK25832
88 Followers 5K Following
Francine Moreno @MorenoFran30832
64 Followers 5K Following
us_Kayla_ @UsKayla19084
0 Followers 125 Following 🎭 Theatre lover & drama enthusiast | Wine connoisseur & foodie | Savoring the flavors of life, both on stage and on plate 🍷🎭
Addison @Addison6222830
0 Followers 114 Following 📖 Bookworm & literary lover | Tea addict & cozy enthusiast | Escaping reality one page at a time 📚☕️
Dawn Loots @DLoots39524
33 Followers 5K Following
Darko Medin @MedinDarko
598 Followers 649 Following Senior Biostatistics Constultant. Data Scientist/Biology AI expert, Researcher. R and Python programmer. Contractor / Collaborating with CROs/Academia
Zoya Billow @billow_zo
32 Followers 5K Following
Isabel @isabel_queal_
144 Followers 3K Following
Lukas B Krone @LBKrone
451 Followers 344 Following Sleep(ing) neuroscientist and somnologist 💤🪰🐭😴👨⚕️ dreaming to become an astronaut 👨🚀 🚀🌍🌖 @OxNeuro @unibern @OxSCNi @Oxfordcircuits @wellcometrust
Elizabeth Barnett @ElizabethB15398
78 Followers 3K Following
Ankur Parikh @ank_parikh
3K Followers 3K Following Staff Research Scientist at Google DeepMind. Former adjunct assistant prof at @NYU_Courant. PhD at @mldcmu. ML for Bio/Chem (Prev. NLP). All opinions my own.
Constantine Tzouanas @constantine_sci
375 Followers 696 Following Making every day in lab as unique as every single cell | @shaleklab | Harvard-MIT @mit_hst | @HertzFoundation Fellow | @NSFGRFP Fellow
Imogen @soughm60527
332 Followers 5K Following See the world on the road, and get to know yourself on the way!
Hao Yin @HaoYin20
9K Followers 10K Following Cardiovascular biologist, Pickering lab, Robarts Research Institute @WesternU; PhD @UCalgary; BSc @PKU1898 Views are my own Just call me Hao :)
Whitney @Smeetea196871
378 Followers 5K Following See the world on the road, and get to know yourself on the way!
Eli Church @church55919
112 Followers 3K Following
thesify @thesify_ai
2K Followers 3K Following Your AI writing coach for essays, reports, and theses.
Dwayne @satodasef94986
393 Followers 5K Following See the world on the road, and get to know yourself on the way!
Kasia Kędzierska �.. @kzkedzierska
686 Followers 544 Following currently on the job market | computational biology & ML | PhD student @UniofOxford | prev: intern @MSFTResearch New England, @novonordisk | she/her
Laura Jiménez Gracia @ljimenezgracia
730 Followers 841 Following PhD Fellow at Single-cell Genomics Team - @hoheyn Lab, @cnag_eu | Teaching | Bioinformatics & Biomedicine | Food lover, always learning & enjoying outdoors!
Sharon @baugussharon42
183 Followers 3K Following
Olin @seeteele71403
390 Followers 5K Following See the world on the road, and get to know yourself on the way!
Flora @Gasasyt142786
321 Followers 5K Following See the world on the road, and get to know yourself on the way!
Meghan Retka @retka84401
138 Followers 3K Following
Helen @frias57helen
228 Followers 3K Following
Rebellious @Testea372640
394 Followers 5K Following See the world on the road, and get to know yourself on the way!
TransCure bioServices @_TransCure
301 Followers 2K Following The only #CRO specialized in #HumanizedMice #MouseModels for #Oncology #ImmunoOncology #AML #InflammatoryDiseases #IBD #InfectiousDiseases #HIV studies
Russell Zhang Kunes @russell_kunes
500 Followers 2K Following Computational biologist at Memorial Sloan Kettering Cancer Center, PhD in Statistics at Columbia
Thomas Walle @science_wallet
786 Followers 976 Following trying to help patients by understanding their individual immune status 🇪🇺🇺🇸 https://t.co/fvbzNRmYGZ…
Elizabeth @elizabe83426510
369 Followers 3K Following
Van Dijk Lab @david_van_dijk
4K Followers 3K Following Assistant Professor @Yale @YaleMed @YaleCompsci | ML/AI comp bio
Austin Argentieri @austinargen
106 Followers 153 Following Using big data to study aging and chronic disease risk @broadinstitute and @MGHMedicine. Previous postdoctoral researcher @bdi_oxford.
Hamza Farrell @farrell_ha61647
114 Followers 3K Following
Ke Yuan @keyuan1
353 Followers 925 Following Senior Lecturer @GlasgowCS @UofGlasgow | Machine Learning & Computational Biology
MAIDEN @MAIDEN_MAFLD
10K Followers 8K Following Metabolic Dysfunction-Associated Fatty Liver Disease Consortium (MAIDEN) official account.
Ana Viñuela @anavinuela
2K Followers 1K Following Computational Biologist, quantitative geneticist, T2D, ageing. Member of @ComunidadCeru English/Spanish. She/her/ella Mastodon: @[email protected]
EPSRC CMAC @EPSRC_CMAC
1K Followers 644 Following World Leading Centre for Medicines Manufacturing Research, Skills, Facilities and Translation.
Hussain Abbas @HussainAbbas_HK
79 Followers 155 Following General Surgery Registrar | HPB and Liver Transplant | Normothermic machine perfusion research | Academic Clinical Lecturer, University of Oxford | Views my own
Will Quince MP 🇬�.. @willquince
24K Followers 4K Following Member of Parliament for Colchester. Former Health, Education and DWP Minister. Promoted by Will Quince MP of 4 Wyncolls Road, Colchester, CO4 9HU
Jamie Cartland @jamieconduit
260 Followers 842 Following Co-founder @ Conduit. Imagining a future where we can deploy global computational expertise to our toughest biopharma challenges. Also try music (Clouded on SC)
Mikaela Koutrouli @MKoutrouli
348 Followers 287 Following PhD Scholar @cphbiosciphd @UCPH_CPR in the group of @larsjuhljensen | Interested in single-cells, deep learning, networks | Community manager @scverse_team
Anshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundaje
Lior Pachter @lpachter
44K Followers 2K Following Bren Professor of Computational Biology @caltech. Blog at https://t.co/FFQzhEsmhi. Tweets represent my views, not my employer's. #methodsmatter
Manolis Kellis @manoliskellis
25K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute
Fabian Theis @fabian_theis
29K Followers 446 Following Computational biologist @HelmholtzMunich, prof @TU_Muenchen & associate PI @sangerinstitute. Dad of 4 and mountain lover. Department news, see @CompHealthMuc
Michael Love @mikelove
18K Followers 5K Following I'm not on twitter anymore, find my on Bluesky or Mastodon
Ming "Tommy" Tang @tangming2005
30K Followers 2K Following Director of computational biology. On my way to helping 1 million people learn bioinformatics. Educator, Biotech, single cell. Also talks about leadership.
Iannis Aifantis @iannisaifantis1
9K Followers 863 Following Cancer Research & Immunology. Professor and Chair @NYUGSOM_Path @nyugrossman. My Instagram (iannis.aifantis) is more fun. Opinions my own.
Veera Rajagopal @doctorveera
17K Followers 4K Following MBBS, MD, PhD | GWAS storyteller | Scientist at Regeneron | Human genetics & drug discovery in Neuroscience & Psychiatry | He/Him
Ewan Birney @ewanbirney
50K Followers 2K Following Deputy Director General of EMBL, Director of EMBL-EBI. I have an insatiable love of biology. @[email protected]. I also work with ONT, Dovetail + GeL.
Akis Papantonis @AkisPapantonis
3K Followers 1K Following Professor for Translational Epigenetics, University Medical Centre Goettingen, University of Goettingen, DE …oftentimes aspiring fiction writer.
Evangelia Petsalaki @e_petsalaki
2K Followers 577 Following Group Leader at EMBL-EBI, interested in context specific regulation of human cell signalling. Mastodon: @[email protected]
Antoine Hocher @antoine_hocher
465 Followers 648 Following Systems biology and evolution of chromatin Post-doc in the Molecular Systems Laboratory, MRC-LMS Incoming group leader, Genetics Dept, University of Cambridge
Florian Markowetz @markowetzlab
4K Followers 2K Following Computational Oncology at Cambridge | chromosomal instability | genomes and images | selfish about reproducibility | all fox, no hedgehog
dana_peer @dana_peer
13K Followers 164 Following
Eytan Ruppin, MD, PhD @NCIEytanRuppin
5K Followers 2K Following Chief, Cancer Data Science Laboratory, CCR/NCI | Computational biology, precision oncology, immunotherapy | Lab-run account Privacy: https://t.co/vMCvc3AIHE
Christoforos Nikolaou @guilderstern
1K Followers 671 Following Computational Biologist, Researcher at @BSRC_Fleming, author and amateur sports journalist. "What difference can you make, a single man in all this madness?"
Prof. Nikolai Slavov @slavov_n
14K Followers 264 Following Mentor, scientist & engineer. Director of @ParallelSqTech. Having fun in @SlavovLab with single-cell proteomics & ribosomes. Organizer of @SCP_meeting
Vince Buffalo @vsbuffalo
15K Followers 2K Following Evolutionary genetics postdoc @UCBerkeley ♥s biology, running, probability+statistics, 🦀, fly fishing, backpacking. Author of book Bioinformatics Data Skills
Alex Colville @AlexJColville
3K Followers 432 Following General Partner at @age1vc extending healthy lifespan. PhD alum of @Thomas_Rando @stanfordmed
Altos Labs @altos_labs
20K Followers 29 Following Altos Labs is a biotechnology company dedicated to unraveling the deep biology of cell rejuvenation to reverse disease.
Maria Brbic @mariabrbic
1K Followers 185 Following Assistant Professor of #computerscience at @EPFL @ICepfl @epflSV Previously @Stanford #machinelearning #compbio
Peterhouse Cambridge @Peterhouse_Cam
5K Followers 337 Following Tweeting the latest news from Peterhouse as well as Petrean news and events.
Lukas B Krone @LBKrone
451 Followers 344 Following Sleep(ing) neuroscientist and somnologist 💤🪰🐭😴👨⚕️ dreaming to become an astronaut 👨🚀 🚀🌍🌖 @OxNeuro @unibern @OxSCNi @Oxfordcircuits @wellcometrust
Matt Coelho @MatthewACoelho
282 Followers 272 Following Cancer Research UK Career Development Fellow at the Wellcome Sanger Institute functional genomics - gene editing - drug resistance - cancer
Ankur Parikh @ank_parikh
3K Followers 3K Following Staff Research Scientist at Google DeepMind. Former adjunct assistant prof at @NYU_Courant. PhD at @mldcmu. ML for Bio/Chem (Prev. NLP). All opinions my own.
Patrick Schwab @schwabpa
5K Followers 2K Following Senior Director Machine Learning & AI @GSK. Prev: ML @Roche, PhD @ETH. ML for Drug Discovery and Health.
Bo Wang @BoWang87
8K Followers 2K Following Assistant Prof. CS,LMP @UofT; CIFAR AI Chair @VectorInst; Chief AI Scientist, @UHN; former PHD, CS @Stanford; opinions my own. #AI #healthcare #combio
Brad Loncar @bradloncar
69K Followers 365 Following #Biotech, Founder of @BiotechTVHQ, KC native, @univmiami hurricane.🧬🙌
Shalek Lab @shaleklab
3K Followers 122 Following Alex K. Shalek Lab @MIT/@ragoninstitute/@broadinstitute/@harvardmed/@MGH_RI. Genomics, immunology, systems biology.
Constantine Tzouanas @constantine_sci
375 Followers 696 Following Making every day in lab as unique as every single cell | @shaleklab | Harvard-MIT @mit_hst | @HertzFoundation Fellow | @NSFGRFP Fellow
nik t. hatziefstathio.. @nikthehat
40K Followers 4K Following ⌗ Innovator-in-Chief ⇢ ❍ne World ✍︎ Investigative Journalist & Director of Open Records Strategy ⇢ AtNight Media ⌇ The New Way ® | One World 🌍
Hao Yin @HaoYin20
9K Followers 10K Following Cardiovascular biologist, Pickering lab, Robarts Research Institute @WesternU; PhD @UCalgary; BSc @PKU1898 Views are my own Just call me Hao :)
Emily Riederer @EmilyRiederer
8K Followers 5K Following Three R's in my last name, but it's not enough #rstats for me! Sr Analytics Manager at Capital One Math/Stats at UNC CH https://t.co/4stm3KVbBX
Richard Sever @cshperspectives
21K Followers 1K Following Assistant Director of Cold Spring Harbor Laboratory Press, bioRxiv & medRxiv Co-Founder
Paul Harrison @pfh@ma.. @paulfharrison
714 Followers 238 Following Bioinformatician with the Monash Bioinformatics Platform. I aim to control my false statement rate.
Eric Lubeck @eric_lubeck
264 Followers 976 Following
🔥 Matt Dancho (Bus.. @mdancho84
54K Followers 464 Following On a mission to grow your business data science skills and accelerate your career | Get my free 5-day business for data scientists course 👇
Generate:Biomedicines @generate_biomed
4K Followers 51 Following As pioneers in generative biology, we're revolutionizing the way biotherapeutics are discovered and developed.
Kevin K. Yang 楊凱�.. @KevinKaichuang
16K Followers 5K Following Senior Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
I Am Biotech @IAmBiotech
106K Followers 6K Following I Am Biotech is where biotech professionals and enthusiasts can come together and discuss the promise of biotech innovation. #Biotech
Biotech Hangout @BiotechCH
12K Followers 451 Following Weekly discussion of biotech news w/ @daphnezohar @bradloncar @timopler @LifeSciVC, @cngarabedian, top analysts & a community of biotech insiders
PureTech @PureTechH
4K Followers 1K Following We're a biotherapeutics company dedicated to giving life to new classes of medicine to change the lives of patients with devastating diseases #Nasdaq #FTSE250
Robert Nelsen @rtnarch
24K Followers 420 Following Company founder and venture capitalist focused on disruptive innovation, esp. biotechnology. Active angel in tech. Fierce Optimist.
LomvardasLab @LomvardasLab
2K Followers 2K Following Laboratory of Stavros Lomvardas, PhD Zuckerman Mind Brain Behavior Institute | Jerome Greene Science Ctr https://t.co/OPR19GE561
Hongyu Ren @ren_hongyu
3K Followers 595 Following Research Scientist @openai. CS PhD @stanford. Previously @apple, @googleai and @nvidiaai. I train language models.
Camilo Ruiz @_camiloruiz
851 Followers 1K Following PhD @Stanford with @jure | AI for Biology | Previously @MIT, @Gates_Cambridge, @Cambridge_Uni
Ang Cui, Ph.D. @AngCuiPhD
988 Followers 85 Following Assistant Professor at Harvard University. Immunology & Big Data. Director of Systems Immunology Research Laboratory @dental_harvard @harvardmed @broadinstitute
PostCheetah @PostCheetah
4K Followers 63 Following Combining AI + Google Metrics to Bring Your SEO Into Overdrive.
Michael Galkin @michael_galkin
5K Followers 269 Following AI Research Scientist @Intel AI Lab. Prev: Postdoc @Mila_Quebec & McGill. GraphML, Knowledge Graphs, GNNs, NLP. Grandmaster of 80's music (according to Spotify)
Arjun Krishnan @compbiologist
1K Followers 306 Following ML & data-driven discovery; Complex traits & diseases; Data reuse & open science. Associate Professor | Group leader @KrishnanLab | @compbiologist everywhere
Kasia Kędzierska �.. @kzkedzierska
686 Followers 544 Following currently on the job market | computational biology & ML | PhD student @UniofOxford | prev: intern @MSFTResearch New England, @novonordisk | she/her
Yanay Rosen @YanayRosen
334 Followers 306 Following CS PhD Student at Stanford. Machine Learning + CompBio Website: https://t.co/F7vi7UkTaC
Stephen Quake @StephenQuake
4K Followers 334 Following Head of Science @chanzuckerberg | Professor of #bioengineering and Applied Physics @stanford | Prolific #inventor focused on nexus of #biology, #physics + #tech
Laura Jiménez Gracia @ljimenezgracia
730 Followers 841 Following PhD Fellow at Single-cell Genomics Team - @hoheyn Lab, @cnag_eu | Teaching | Bioinformatics & Biomedicine | Food lover, always learning & enjoying outdoors!
Demis Hassabis @demishassabis
356K Followers 125 Following Co-founder & CEO @GoogleDeepMind - working on AGI. Trying to understand the fundamental nature of reality. Also revolutionising drug discovery @IsomorphicLabs
Phenomic AI @PhenomicAI
473 Followers 65 Following A team of experimental scientists and deep-learning programmers. We combine relevant clinical models with cutting edge AI in order to discover new therapies.
Cameron Park @cam_park
210 Followers 181 Following Link to most recent preprint! https://t.co/2UeWhQKfVW
Felix Teufel @felixgteufel
242 Followers 161 Following PhD Student at @novonordisk and @UCPH_Research prev. Biotechnology @ETH
Kheiron @KheironMedical
2K Followers 771 Following Our mission is to give every woman a better fighting chance against breast cancer. Proud winner of the UK Government’s new AI awards https://t.co/URLsBX3Jyy
Chenxin Li, PhD (@che.. @ChenxinLi2
8K Followers 3K Following Or just Li | Postdoc @ UGA | Decoding how genome, development, and environment shape (specialized) metabolism | Also post data visualization
Dominique Beaini @dom_beaini
3K Followers 492 Following Lead researcher at @valence_ai, Adjunct Prof. at @UMontreal, Associate prof at @Mila_Quebec, interested in drug discovery, GNN, physics, robotics, biology
Lukas Valihrach @LukasValihrach
3K Followers 767 Following Group Leader | 🧬Single-Cell & Spatial Transcriptomics | Epigenomics | 🧠Neurobiology | Glial Cells in Health & Disease | @labgenex @IBT_CAS 🇪🇺 | ❤️ My Twins
Ioannis Vlachos @ioavlachos
1K Followers 304 Following Director of Spatial Technologies & Bioinformatics. BIDMC / HarvardMed / Broad.
David Kelley @drklly
2K Followers 659 Following Using computers to understand the molecular logic of life.
Valence Labs @valence_ai
4K Followers 28 Following Harnessing computation to radically improve lives. Powered by @recursionpharma
Regeneron enter the corporate venture game. A good addition. endpts.com/regeneron-ente…
Job alert! We offer two positions (Team leader & Bioinformatics developer) to work on the Biodiversity Cell Atlas database: unified pipelines, data curation, and cross-species integration. With @irenepapatheodo @RodericGuigo @ExpressionAtlas @emblebi 🗓️Apr-10 🔗Details below
How to link single-cell diversity and the emergence and maintenance of robust multicellular processes in developed tissues? 🤔 What can we learn about multicellular coordination in tissues from single-cell omics data? Read about our view: arxiv.org/abs/2403.06753
Google's new scholar PDF reader extension is great. In-text citations are previewable links to references, clickable TOC headings, figure/table references. scholar.googleblog.com/2024/03/superc…
Excited to see the @nytimes article featuring some recent line of work on foundation models like our scGPT in single-cell analysis! In my chat with @carlzimmer, we dived into how foundation models like scGPT are helpful in advancing the development of “virtual cells.” So, what’s…
Opportunities and tradeoffs in single-cell transcriptomic technologies buff.ly/47NcBgv
With six approved drugs, siRNA is now an established therapeutic modality poised for expansion go.nature.com/49tcrf8 rdcu.be/dAsb2
**Is single-cell data integration a solved problem? ** Lots of great methods, but still not quite yet! Specifically, Check Dataset Imbalance! 🎉 Excited to announce that our study on dataset imbalances in single-cell analysis just hit Nature Biotechnology (@NatureBiotech)! 🎉…
Are you looking to apply Large Language Models to biomedical questions? You may want to take a look at our new framework (biochatter.org) and the updated preprint (arxiv.org/abs/2305.06488). 🧵👇
Major Cell2Sentence update 🎉🔬! We’ve been thrilled to see the attention Cell2Sentence has received from the single-cell community. Now, we’re excited to release our first update of Cell2Sentence (C2S) - a framework to leverage LLMs to train foundational single-cell models,…
Our 🪐SATURN method is now out in @naturemethods! SATURN paves the way for universal cell embeddings, enabling integration of datasets across different species 🐒🐁🧍🐟🐸 Using protein language models, we encode biological meaning of genes in scRNA-seq datasets.
SATURN performs cross-species integration and analysis using both single-cell gene expression and protein representations generated by protein language models. @jure @YanayRosen @mariabrbic @yusufroohani nature.com/articles/s4159…
Using Human Protein Atlas to Find Tissue Specific Genes in R using bioconductor buff.ly/3OK6DpH #rstats
Surgeons have successfully attached a gene-edited pig liver to a patient – for 3 days! 📈 Researchers believe the livers could be used to support for #LiverDisease patients awaiting transplants. @statnews: statnews.com/2024/01/18/ege… @WIRED: wired.com/story/gene-edi…
GeneGPT: Augmenting large language models with domain tools for improved access to biomedical information academic.oup.com/bioinformatics… 🧬🖥️ github.com/ncbi/GeneGPT
Interesting spread of IPO dollars by indication area.
IPO Biotech Themes (2019-2023) *I&I theme had an "oncology moment" in 2023 - however Infectious disease theme evaporated ! *CNS came back last year and spilling into this year
{searcher} 0.0.7 is here with the ability to search code in public GitHub repos with grep.app 📦 and enjoy anonymous searching with Qwant 🕵️♂️ right from #rstats. cran.r-project.org/web/packages/s…
In October ‘23, @stateofaireport reached its 5th anniversary. With 934 slides over 6 editions serving as a historical document, we’re opening 2024 with a retrospective of the main storylines, what we predicted, and what we didn't. Welcome to the State of the State of AI. 🧵
🔬Is the future of liver therapies better #AI or better #data? In a conversation with @PharmaTimes, our CSO & co-founder @QuinWills talked about the urgent challenge of #LiverDisease and our world-first ‘liver ICU’. Read now (page 32) ⬇️ magazine.pharmatimes.com/#/reader/50929…
"The average R&D efficiency of big pharma was $6.16 billion total R&D expenditures per new drug." 😱 And remember, that's the average, meaning ~half are higher than that! @ideapharma $XBI sciencedirect.com/science/articl…
Trends for United States
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