Saez-Rodriguez Group @saezlab
Account of the Saez-Rodriguez lab at Heidelberg University Lab members tweet about our news, activities & publications Also at: https://t.co/YFqkPcH6dY saezlab.org Heidelberg, Germany Joined March 2012-
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Our alumna Sophia Müller-Dott was honored with the MTZ Award for Systems Medicine for her PhD work. Congratulations, @sophia_mullerd ! 🎉 A special thanks to Monika and Thomas Zimmermann from the @MTZfoundation for their enduring support of Systems Medicine. 🙌
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Led by José Linares Blanco, supervision from @JulioSaezRod and @roramirezf94, contributions from @psl_schaefer, Leoni Zimmermann, Ricardo Melo Ferreira, Daniel Toro Dominguez, @pcarmonasaez, @tanevski, Marta E. Alarcon Riquelme and Michael T. Eadon.
Together, this links systemic immune programs measured in blood to local tissue pathology in lupus nephritis. We see our patient map as a reference where SLE or other autoimmune cohorts can be analyzed. GitHub: github.com/saezlab/metalu…
1/🧵New preprint! We built a patient-level map of systemic lupus erythematosus using single-cell blood transcriptomics, linking multicellular immune coordination to patient heterogeneity, future disease activity, and potential tissue pathology. ➡️ doi.org/10.64898/2026.…
This month we welcome Ajita Shree as a postdoctoral researcher, who will be working on computational methods for cell–cell communication🎉. Ajita has a background in developing deep generative models for single-cell & spatial transcriptomics.
Great to see how Tunca Doğan's team, our collaborators at Hacettepe University, used OmniPath software for building CROssBARv2 and grateful for their contributions to OmniPath development. See details below 👇
🚀 Exciting news! Our project, CROssBARv2, is now live as an online tool and its article (preprint)! We've built a unified AI-powered platform that brings together the fragmented world of biomedical data — and lets you talk to it in plain English. Here's the story 👇 The
This work was led by Robin Fallegger and Sergio A. Gomez-Ochoa, supervised by @JulioSaezRod with Matthias Kretzler and Michael T Eadon. Thanks to all involved, including Charlotte Boys, @roramirezf94, @tanevski, and many more. We thank all funders and patient participants!
A step toward molecularly grounded, precision assessment of kidney injury and the possibility of non-invasive tracking of tissue damage using blood and urine biomarkers.
What does single-cell transcriptomics reveal about individual patients with acute (AKI) and chronic (CKD) kidney 🫘 disease? Can we use it to find new biomarkers? In our new preprint, we asked this using biopsies from 150+ participants from the Kidney Precision Medicine Project.
This study was led by @l_kuechenhoff, with supervision by @JulioSaezRod and @roramirezf94 & contributions from Gahyun Kim, @JanLanzer, and Matthias Kretzler. We greatfully acknowledge funding from the German Federal Ministry of Research, Technology, and Space (@bmftr_bund)
We further combine single-cell data with spatial transcriptomics to identify spatially constrained fibrotic cell signalling events shared across organs. All results are published as an open resource to support further discovery: organfibrosis.saezlab.org
🧵 See 👇 our new preprint on shared and organ-specific gene expression programs of fibrotic diseases 🧬 📄 Paper: doi.org/10.64898/2026.… 📊 Explore the data: organfibrosis.saezlab.org
Fabian Theis @fabian_theis
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Ming "Tommy" Tang @tangming2005
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Ci Chu @inCiChu
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Harish Narasimhan @hnarasim23
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Itai Yanai @ItaiYanai
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Prof. Nikolai Slavov @slavov_n
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Lior Pachter @lpachter
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Manolis Kellis @manoliskellis
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Arjun Raj @arjunrajlab
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Mo Lotfollahi @mo_lotfollahi
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Costa Lab - @costalab... @vanvanka123
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Matthias Mann Lab @labs_mann
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Anshul Kundaje @anshulkundaje
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Pedro Beltrao @pedrobeltrao
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EMBL @embl
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Uri Alon @UriAlonWeizmann
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Kerstin Göpfrich @KGoepfrich
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Eytan Ruppin, MD, PhD @EytanRuppin
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Daniela Robles @danie... @daniela_oaks
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Nadine Tüchler @NadineTuechler
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Ahmet Rifaioğlu @ahmet_rifaioglu
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Daniel Guerrero-Romer... @DannGuerreroR
374 Followers 509 Following Postdoctoral fellow EMBL-EBI & AstraZeneca UK | Interested in studying mathematical & ML approaches in cancer evolution and drug response.
Shyam Prabhakar Lab @shyam_lab
2K Followers 514 Following Associate Director Spatial and Single Cell Systems @astar_gis. Genomics: algorithms, disease markers & mechanisms, genetic diversity [email protected]
Carl Anderson @anderson_carl
3K Followers 902 Following Head of Human Genetics and Senior Group Leader (Genomics of Inflammation and Immunity) at Wellcome Sanger Institute. #firstgen
Sara Aghamiri @SaraAghamiri_
189 Followers 407 Following Entrepreneur | Human Digital Twin developer | Biomedical Engineer | @UnivParisSaclay @Inserm @EU_Commission @UNLincoln @SIIM_Tweets🎾🎹🎮🎨♟️
Nadav Yayon @YayonNadav
426 Followers 419 Following Postdoctoral fellow at the labs of Sarah Teichmann (Sanger), John Marioni and Virginie Uhlmann (EMBL-EBI). PhD in molecular and computational neuroscience.
European Society for ... @SpatialBio
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EMBL-EBI @emblebi
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The BATLLE Lab @BatlleLab
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Gary Siuzdak @kadzuis
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404 Followers 646 Following Professor of Pediatrics & Medicine @UWEndocrinology and @seattlechildren. Raisbeck Endowed Chair of Diabetes Research. Director @UWMDI_UWMed.
Roser Torra @torra_roser
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Chiadi Ndumele @ChiadiNdumele
555 Followers 89 Following Associate Professor, Cardiology @hopkinsheart @HopkinsMedicine | Director of Obesity and Cardiometabolic Research @CiccaroneCenter | Husband, father and son
Morgan Grams @meg21212
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Valentina Boeva @val_boeva
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775 Followers 358 Following Associate Professor, Renal Pathologist and #kidneyomics Researcher. Tweets are my opinions not medical advice. #renalpath
Titus J. Brinker, MD @TitusBrinker
886 Followers 312 Following Head of AI Division at the German Cancer Research Center: https://t.co/kFlcJzItuA
Emmanuel Saliba @AE_Saliba
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Verónica Lloréns-Ri... @VeroLlorens
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Nicola Segata @nsegata
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Victor Paton @vicpaton
69 Followers 91 Following PhD candidate at @EMBL @EMBLBarcelona, previously @UniHeidelberg @saezlab. Also in Bluesky https://t.co/2JDEEyNskj
Dr. Tijana Milenkovic @ProfMilenkovic
702 Followers 238 Following Professor of #ComputerScience. Researcher in #NetworkScience & #ComputationalBiology. Huge #CocaColaFan. Even bigger #DogPerson. We need more #WomenInComputing!
Matthias Lutolf @TheLutolfLab
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Alicia Oshlack @AliciaOshlack
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5K Followers 578 Following Functional human genomics @ KTH, SciLifeLab, NY Genome Center. Pro science here, more fun stuff fun at @tuuliel. Mastodon [email protected]
Muzlifah Haniffa @Muzz_Haniffa
2K Followers 365 Following Clinician #scientist passionate about #immunobiology & #genomics. Mother, mentor, food enthusiast & film buff!
Barbara Engelhardt @BeEngelhardt
10K Followers 995 Following Machine learning, statistical genomics, ML4 health, senior investigator at Gladstone Institutes, professor at Stanford, single mom to four kids. she/her
Nicole Soranzo @nicolesoranzo
4K Followers 3K Following Human geneticist. Senior group leader at @sangerinstitute and @cambridge_uni, Head of Genomics @humantechnopole
Health + Life Science... @ResearchLifesci
992 Followers 190 Following Health + Life Science Alliance #Heidelberg #Mannheim - Center of Excellence in the #Life Sciences
Opitz lab @LabOpitz
429 Followers 290 Following
Rafael Irizarry @rafalab
29K Followers 490 Following Applied statistician. I tweet data-driven observations, data science educational materials, academic research updates, and the occasional joke.
Pierre-Louis THARAUX @PLTharaux
941 Followers 2K Following M.D., PhD. INSERM Prof #nephrology #vasculitis #LaSciencePourLaSanté #therapies for #rare diseases #kidneydiseases Les tweets ne sont pas des conseils médicaux
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645 Followers 128 Following Analyzing and modeling single cells in biomedical data
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410 Followers 218 Following Endocrinology and nutrition group at Hospital Universitario La Princesa (Spain). Research and clinics. Group leaders: Mónica Marazuela and Rebeca Martínez
Shaun Mahony @mahonylab
2K Followers 1K Following Studying gene regulation and transcription factor binding specificity with machine learning. Assoc Prof @ Penn State. 🇮🇪
HI-STEM - Cancer and ... @hi_stem_lab
2K Followers 1K Following The Stem Cell Research Institute @DKFZ HI-STEM (Heidelberg Institute for Stem Cell Technology and Experimental Medicine) gGmbH Head: Andreas Trumpp
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823 Followers 591 Following Multidisciplinary division at DKFZ and NCT Heidelberg focused on translational cancer research and precision oncology trials.
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584 Followers 267 Following Our group's aim is to identify pathogenetic mechanisms in acute leukemias and other cancers to ultimately develop and test novel therapy approaches
Xiao Wang @WangXiaoLab
6K Followers 508 Following Associate Professor at MIT Chemistry and Core Member at Broad Institute of MIT and Harvard
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scverse
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@dominic_grun
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Holger Heyn
@hoheyn
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