Joseph Therriault @JosephTherr
Molecular Imaging, Neurodegeneration, Behavioural Neurology. Songs @gulfergulfer 👨🍳 🎸 🚲 Joined July 2020-
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Editor pick from April issue @JosephTherr @NicholasAshton @pedrorosaneto @andrealessa & coll Compared the performance of two commercially available plasma p-tau217 assays in 294 individuals with #Alzheimer's disease. Read bit.ly/4aLAGWN
preprint 👇 Temporal lobe #epilepsy gradually perturbs cortex-wide excitation-inhibition balance ⚡️⚖️ @KeXie20 🧙♂️combined connectomics, biophysical models, and EEG/cognitive phenotyping to identify mechanisms & consequences of E/I imbalance in TLE 👉bit.ly/EI-Epilepsy
Congratulations to @pedrorosaneto for winning the Alzheimer's Association "Excellence in Neuroscience Mentoring" Award! Anyone would be lucky to have you as a mentor and I am so grateful to be one of the lucky ones 🥹🎉 @alzassociation
***Hot off the @JAMANeuro e-press*** While seeking to investigate clinicopathologic heterogeneity and glial activation patterns of #Alzheimers...we created a corticolimbic index (CLix) to better capture the individuality of tangle distribution. jamanetwork.com/journals/jaman…
In @alzdemjournals, we describe a new method for tau aggregates: - specific to soluble/solubilized tau aggregates vs. monomers; - applies to Alzheimer brain-derived homogenates🧠; and - increases with Braak staging. Next step: human CSF & blood 🩸 alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…
After a long break we are finally back with a new @rbiq_qbin podcast episode with the great @KcD_PhD !!! We discussed the topic of racial disparities, access barriers, test validity, and inclusivity initiatives please check it out and share share share!! blog.rbiq-qbin.qc.ca/2024/03/21/emb…
It seems that we can get accurate information about the individual-level disease stage of AD by just analyzing one single CSF sample for 5 key AD biomarkers. Hopefully this staging paradigm can be transferred to blood very soon, using even fewer biomarkers!
It seems that we can get accurate information about the individual-level disease stage of AD by just analyzing one single CSF sample for 5 key AD biomarkers. Hopefully this staging paradigm can be transferred to blood very soon, using even fewer biomarkers!
In our paper @NatureComms, we evaluated whether AD 🩸 biomarkers could aid in selecting memory clinic patients who’d more likely prognostically benefit from undergoing tau-PET, with p-tau217 performing best @OskarHansson9 @pedrorosaneto @biofinder_study nature.com/articles/s4146…
Happy to share that my first original study as a PhD student is now published in @braincomms. It talks about the use of tau-PET to predict impairment in activities of daily living in Alzheimer's disease. Big thanks to my team for all the support🧠 academic.oup.com/braincomms/art…
New online! Biomarker-based staging of Alzheimer disease: rationale and clinical applications go.nature.com/3TjXoPq
Data driven "Jack curves": We used an amyloid PET clock to determine the timing of biomarker change in sporadic Alzheimer disease in terms of years until symptom onset. #ENDALZ @WashUNeurology onlinelibrary.wiley.com/doi/10.1002/an…
Can a blood test replace CSF tests and amyloid-PET in the diagnostic work-up of AD in specialist care? The present study shows that this is the case in most patients with cognitive impairment, where plasma %ptau217 performs equivalent or better to FDA-approved CSF tests.
Can a blood test replace CSF tests and amyloid-PET in the diagnostic work-up of AD in specialist care? The present study shows that this is the case in most patients with cognitive impairment, where plasma %ptau217 performs equivalent or better to FDA-approved CSF tests.
❗️Publication❗️ Head-to-head comparison between a highly accurate plasma biomarker and FDA-approved and clinically used CSF biomarkers 🩸#ptau217 is clinically comparable or superior to CSF biomarkers to detect #Alzheimer's pathologies @NatureMedicine nature.com/articles/s4159…
Thanks to Maria Carrillo and Simin Mahinrad for a wonderful commentary on our recent paper examining the relationships of CSF and imaging biomarkers with cognitive measures in Black and White individuals. rdcu.be/dxEy0 @DrMariaALZ @SMahinrad #ENDALZ @NatRevNeurol
The era of commercial #blood tests for #Alzheimer disease is near. We evaluate the @AlZpath #pTau217 blood test in 3 independent cohorts🇺🇸🇨🇦🇪🇸 ➡️ Consistent high acc. for amyloid & tau (>0.95) ➡️ Reproducible cut-offs ➡️ ~80% reduction in adv. testing jamanetwork.com/journals/jaman…
Prof. Melissa E. Murr.. @DrNeuroChic
5K Followers 1K Following Translational neuropathologist | Biomarker enthusiast | Hopeful scientist | Scientific Program Committee @HAIconference #AAIC24 | Advisory board #ADPD2025Nick Corriveau-Lecava.. @CorriveauNick
5K Followers 3K Following Neuropsychologist studying the degenerating mind at @MayoClinic @NaipMayo | Assistant Prof @MayoClinicNeuro & @MayoPsychPascoal Lab @LabPascoal
2K Followers 925 Following Lab based at University of Pittsburgh interested in diagnostic and therapeutic approaches in neurodegeneration | PI: @TharickAPascoalGemma Salvadó @gesalbla
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755 Followers 659 Following Postdoc at @BerkeleyLab/@UCBerkeley |PhD neuroscience at @mcgillu, visited @PittTweet |Fluid biomarkers & PET |🇦🇷🇫🇷🇧🇷🇨🇦🇺🇸📍| she/herNicholas Ashton @NicholasAshton
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4K Followers 3K Following PI @ufrgsnoticias @zimmerneurolab | Adjunct professor @mcgillu | Research associate @cerebro_rs | Interested in glia and neurodegeneration.Rosa Neto, Pedro - @pedrorosaneto
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153 Followers 237 Following Professor & PI at UFGRS (@ufrgsnoticias), affiliate member at McGill (@mcgillu) | 🧠🐭👩🏻🔬💊🌶Johannes Lohmeier @lohmeier_
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275 Followers 665 Following @alzassociation Research Fellow @Bruneluni #dementia #neuropsychology #mri diverse older adults (my own views) 🧠🏳️🌈🇪🇺 He/Him3rd Edition Global Lo.. @Longevity25252
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5K Followers 3K Following Neuropsychologist studying the degenerating mind at @MayoClinic @NaipMayo | Assistant Prof @MayoClinicNeuro & @MayoPsychPascoal Lab @LabPascoal
2K Followers 925 Following Lab based at University of Pittsburgh interested in diagnostic and therapeutic approaches in neurodegeneration | PI: @TharickAPascoalRikOssenkoppele @RikOssenkoppele
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4K Followers 3K Following PI @ufrgsnoticias @zimmerneurolab | Adjunct professor @mcgillu | Research associate @cerebro_rs | Interested in glia and neurodegeneration.Rosa Neto, Pedro - @pedrorosaneto
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2K Followers 921 Following MD Ph.D., Behavioral Neurologist at @UPMC, Associate Professor at @PittPsychiatry and @PittNeurology | @LabPascoalMarianne Chapleau @M_Chapleau
2K Followers 1K Following Neuropsychologist turned Medical Science Liaison. Passionate about patient care & improving the diagnosis of neurodegenerative diseases. Views are my own.Yakeel T. Quiroz, PhD.. @ytquiroz
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170 Followers 155 FollowingManuel Friese @ManuelFriese
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28K Followers 5K Following Epidemiologist + Statistician | @HRBIreland @CRF_Cork @UCCPublicHealth @UCC | #ClinicalTrials #EpiTwitter #StatsTwitter Views mineASA @AmstatNews
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330 Followers 495 Following Postdoctoral researcher at @fz_juelich, interested in amyloid aggregation processes and the study of their structures by cryo-EMBenjamin Ryskeldi-Fal.. @bwfalcon
2K Followers 852 Following Group leader at @MRC_LMB working to understand the molecular mechanisms of neurodegenerative disease (formerly Benjamin Falcon)The most on-brand take of all time.
Just published: My op-ed in the Boston Globe @GlobeOpinion w Jeff Flier @jflier | Academic freedom is not a right to coerce (Why universities should shut down occupations). bostonglobe.com/2024/04/29/opi…
I appreciate how hard Beverley is playing. He’s a game changer for the Bucks
I would really like Bev back next season on a minimum. The Bucks need to get younger, that is the truth, no denying it. That being said, he has been contributing. You need a guy like him on your team. I’ve enjoyed his time here
Cognitively healthy centenarians have lower AD polygenic risk scores. The genetic effects for maintaining cognitive health until extreme ages were specifically concentrated on genes associated with the endolysosomal and immune system (i.e., alleles in/near ANKH, GRN, TMEM106B,…
A woman on CNN is saying the anti-Vietnam protests were different from the situation now, which is “very polarizing.” People always do this — make it seem like past activists were somehow uncontroversial. It’s nonsense. Activism by its nature is antagonistic to the status quo.
An interesting work by @JosephTherr @andrealessa as @eBioMedicine editor pick. Kudos to this great team!
Editor pick from April issue @JosephTherr @NicholasAshton @pedrorosaneto @andrealessa & coll Compared the performance of two commercially available plasma p-tau217 assays in 294 individuals with #Alzheimer's disease. Read bit.ly/4aLAGWN
Editor pick from April issue @JosephTherr @NicholasAshton @pedrorosaneto @andrealessa & coll Compared the performance of two commercially available plasma p-tau217 assays in 294 individuals with #Alzheimer's disease. Read bit.ly/4aLAGWN
2 yrs ago, after 3 days on Twitter, I told my husband I'd maxed out w/57 followers by forcing everyone I knew on Twitter to follow me Then I posted my educational content & everything changed. Now, I have >51 k followers. Thanks to all who helped me & all for their support!
Periodic reminder. This dataset is bullshit. - 104 countries had no data so they guesstimated based on surrounding countries - the IQ for Guinea was based on kids in a mental disability home - one of the authors was ruled a white nationalist by the southern poverty law center
Countries ranked by their average IQ: 1. 🇯🇵 Japan: 106.48 2. 🇹🇼 Taiwan: 106.47 3. 🇸🇬 Singapore: 105.9 4. 🇭🇰Hong Kong: 105.34 5. 🇨🇳 China: 104.1 6. 🇰🇷 South Korea: 102.3 7. 🇧🇾 Belarus: 101.6 8. 🇫🇮 Finland: 101.2 9. 🇱🇮 Liechtenstein: 101.1 10. 🇩🇪 Germany: 100.7 . 16. 🇨🇦 Canada:…
preprint 👇 Temporal lobe #epilepsy gradually perturbs cortex-wide excitation-inhibition balance ⚡️⚖️ @KeXie20 🧙♂️combined connectomics, biophysical models, and EEG/cognitive phenotyping to identify mechanisms & consequences of E/I imbalance in TLE 👉bit.ly/EI-Epilepsy
Regardless of the outcome, so happy for Khris to have a performance like that and shut the haters up. He has been disrespected so much by this fanbase, and I'm glad I never was one of those people.
Big endorsement
Honored to be endorsed by legendary Columbia University Professor Jeffrey Sachs! jillstein2024.com/jeffrey_sachs_… Join us for a rally with Dr. Sachs Fri 5/3 to power up our fight to put an anti-genocide, pro-worker, climate action choice on the ballot nationwide! jillstein2024.com/rally
Doutorando da UFRGS é reconhecido um dos pesquisadores mais promissores do mundo em Neurociência. Prêmio "One to Watch' Award" da Alzheimer's Association foi entregue para João Pedro Ferrari Souza em solenidade nesta quinta, 25, na Universidade de Chicago. tinyurl.com/pj2sdmub
@NesrineR95 @pedrorosaneto @alzassociation @andrealessa @firoza_lussier @erzimmer @TharickAPascoal @JosephTherr @CecileTss @macedoarthurc Congratulations @pedrorosaneto! Super well-deserved! Glad I got the experience of having you as a mentor for a little! 🙏🏻
@NesrineR95 @pedrorosaneto @alzassociation @andrealessa @firoza_lussier @erzimmer @TharickAPascoal @JosephTherr @CecileTss @macedoarthurc Congratulations Pedro!
Congratulations to the amazing @M_Malpetti for the 2024 “One to Watch” award! 👏👏👏👏