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Marianne Chapleau @M_Chapleau

Neuropsychologist turned Medical Science Liaison. Passionate about patient care & improving the dx and tx of neurodegenerative diseases. Views are my own. San Francisco, CA Joined January 2020
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Marianne Chapleau @M_Chapleau

7 months ago

@financedon2024 @vivekramaswami The implication that a man of color following a woman is suspicious or predatory… 🙃

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Marianne Chapleau @M_Chapleau

11 months ago

@grinberg_t @UCSFmac @MayoClinic @gowoon_son @MayoPathology Congrats Lea! Enjoy the sunny Florida weather! ☀️

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Marianne Chapleau @M_Chapleau

a year ago

Big day for Life Molecular Imaging! 👏 investor.lantheus.com/news-releases/…

Marianne Chapleau retweeted
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RikOssenkoppele @RikOssenkoppele

a year ago

🚨NEW PREPRINT: An atypical phenotype is a risk factor for higher mortality in Alzheimer’s disease @ilse_bader shows that an atypical (non-amnestic-predominant) clinical presentation is an important risk factor for mortality beyond age, sex, education, APOEε4-carriership and disease severity. Link @medrxivpreprint: medrxiv.org/content/10.110… @Colin__Groot @AlzheimerAms

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Marianne Chapleau @M_Chapleau

2 years ago

Happy to share this great review on florbetaben, led by Aleksandar Jovalekic, highlighting its pivotal role in imaging Alzheimer’s pathology since its approval 10 years ago. Grateful to have collaborated on this work! mdpi.com/1424-8247/17/1…

Marianne Chapleau retweeted
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Anna Marseglia @anna_marseglia_

2 years ago

📣 Postdoc Hiring📣 Join our project on how social health impacts cognition & resilience with a focus on women’s health 
✅ Longitudinal data expertise 
✅ Passion for aging research
✅ Team-oriented mindset 📍Karolinska Institutet 🇸🇪 
💼 Apply now: ki.varbi.com/en/what:job/jo…

Marianne Chapleau retweeted
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Nico Franzmeier @nfranzme

2 years ago

Massive paper alert: We performed extensive profiling of PI-2620 for 4R tauopathies. PI-2620 tau PET signals in PSP stem from neuronal and oligodendroglial tau, not astrocytes. Signals correlate with fibrillary tau, autoradiography, and autopsy data in PSP doi.org/10.1007/s00401…

Marianne Chapleau retweeted
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JAMA Neurology @JAMANeuro

2 years ago

ARIA-E in Alzheimer disease is more likely in those with APOE ε4, microhemorrhages, low CSF Aβ42, and high Fazekas scores, but it does not generally worsen long-term cognition or function. ja.ma/4fOVui3

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Marianne Chapleau @M_Chapleau

2 years ago

Exciting news for Alzheimer’s treatment in Europe! National decisions on access, pricing, and reimbursement are next, but this is a big step forward! 🎉

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EU Medicines Agency @EMA_News

2 years ago

📢The CHMP recommends authorising a new treatment for early #AlzheimersDisease in the EU. Leqembi is intended for treatment of mild dementia and cognitive impairment in a restricted patient population with a specific genetic make-up. 👉 ema.europa.eu/en/news/leqemb…

Marianne Chapleau retweeted
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CurePSP @CurePSP

2 years ago

#CurePSP is now accepting applications for the Student Fellowship Program. This program supports students engaged in research on PSP and CBD, providing resources to drive meaningful advances in the field. Deadline: January 31, 2025, by 5pm ET psp.org/iwanttolearn/s… #Research

Marianne Chapleau retweeted
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JAMA Neurology @JAMANeuro

2 years ago

Study found frailty accelerates up to 9 years before dementia onset and is a key early marker. Frailty was linked to higher dementia risk even when measured years before dementia onset and may represent a target for prevention efforts. ja.ma/4hLFake

Marianne Chapleau retweeted
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Sara Nolin, PhD 🧠 @SaraNolin_neuro

2 years ago

📢 Looking for a postdoc opportunity in neuroimaging research! 🎓 My focus: Alzheimer’s disease, cognitive aging, & functional networks. Skilled in multiple MRI modalities and neuropsych. Excited to connect with labs! #Postdoc #AlzheimersResearch #Neuroimaging

Marianne Chapleau retweeted
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Maria C Carrillo PhD @DrMariaALZ

2 years ago

Join us at #AAICAdvancements Exploring Equity in Diagnosis, Nov. 18-19 in Chicago and online! Be a part of the conversation around addressing disparities in an era of modernizing diagnosis for Alzheimer’s and other dementias. #ExploringEquity24 alz.org/exploringequity

Marianne Chapleau retweeted
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Jake Vogel @_JakeVogel_

2 years ago

Whelp. Maybe a good time to mention that I am about to open a new PhD position in Sweden that just happens to be exactly four years in length. Any aspiring PhD candidates in neurodegenerative imaging or multiomics who want to "take a break" from the US, please get in touch!

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Marianne Chapleau @M_Chapleau

2 years ago

@elvisha9 Yep… 😞 This feels unreal.

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Marianne Chapleau @M_Chapleau

2 years ago

Well said! And this framework does not diminish the importance of syndromic diagnosis or the quantification of clinical impairment.

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Suzanne E Schindler @SuzanneESchind1

2 years ago

Having started my career in basic neuroscience research, I have always understood Alzheimer disease to mean the pathophysiology associated with amyloid plaques and tau tangles. As a clinician, I appreciate that the relationship between Alzheimer disease and cognitive impairment

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Marianne Chapleau @M_Chapleau

2 years ago

@MilanNigam2 Pour attirer plus de psychologues dans le public, ça prend une meilleure rémunération… Les médecins sont biens au Québec 🙂

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Marianne Chapleau @M_Chapleau

2 years ago

@MilanNigam2 Quand j’ai obtenu mon diplôme en 2020, on nous obligeait, en tant que psys/neuropsys, à accepter un poste dans notre dernier milieu de stage si l’opportunité se présentait. La plupart trouvaient une excuse pour y échapper, car le salaire de base dans le public était de 66 000$.

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Marianne Chapleau @M_Chapleau

2 years ago

@jme_walker 🤣

Marianne Chapleau retweeted
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RikOssenkoppele @RikOssenkoppele

2 years ago

Lewy body pathology exacerbates brain hypo-metabolism and cognitive decline in Alzheimer’s disease Great work led by @LECollij. Using ADNI data, she showed that the presence of LB pathology (CSF SAA) exacerbates global cognitive decline in symptomatic AD and is associated with more pronounced hypo-metabolism (FDG PET), particularly in posterior cortical regions. Link @NatureComms (open access): nature.com/articles/s4146… @biofinder_study @SEMastenbroek @NiklasMattsson4 @SebastianPalmqv @OskarHansson9

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