Wagner S. Brum @wagnersbrum
MD-PhD student working with Alzheimer's disease biomarkers and their clinical interpretation at @goteborgsuni @ufrgsnoticias @zimmerneurolab scholar.google.com/citations?hl=e… Gothenburg, Sweden Joined August 2018-
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Editor pick from April issue @JosephTherr @NicholasAshton @pedrorosaneto @andrealessa & coll Compared the performance of two commercially available plasma p-tau217 assays in 294 individuals with #Alzheimer's disease. Read bit.ly/4aLAGWN
Receiving the 'One to Watch' Award from @alzassociation in the same event that one of the scientists I most admire - @pedrorosaneto - wins the 'Excellence in Neuroscience Mentoring' Award is a unique & incredible feeling! I am so grateful for this moment!
Receiving the 'One to Watch' Award from @alzassociation in the same event that one of the scientists I most admire - @pedrorosaneto - wins the 'Excellence in Neuroscience Mentoring' Award is a unique & incredible feeling! I am so grateful for this moment!
Of 30 patients with severe #SickleCellDisease who were treated with gene-edited autologous hematopoietic stem and progenitor cells, 29 were free from vaso-occlusive crises for at least 12 consecutive months. Read the full CLIMB SCD-121 study results: nej.md/3UvzPDT
Important🩸 biomarker analyses (only plasma Aβ though) from AHEAD 3-45: - In plasma eligible adults, positron emission tomography eligibility rates are similar across race and ethnicity. - Plasma biomarker tests may be similarly effective across racial and ethnic groups
Important🩸 biomarker analyses (only plasma Aβ though) from AHEAD 3-45: - In plasma eligible adults, positron emission tomography eligibility rates are similar across race and ethnicity. - Plasma biomarker tests may be similarly effective across racial and ethnic groups
@seb_walsh @smead2 @pash22 @SuzanneESchind1 @MadhavThambiset @EWidera @ajlees @ProfRobHoward @MemoryDoc @dr_shibley @LonSchneiderMD @_michael_scholl @VincentPlanche @StefanoSensi14 @AlbertoEspay @nvillain_alz @KasperKepp @PhilAlz @Gill_Livingston @jfballenger @jasonkarlawish @JamesRuFletcher @AdamMBrickman @ManlyEpic @SFAckley @FortuneMagazine @TIME @ErinMPrater @TIMEMagazineRS @FT @hannahkuchler @CTADconference @NIH @alzassociation @howard_gleckman @AmerGeriatrics @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @US_FDA @NICEComms @RaymondKoopmans @MaastrichtU @Kariem_Ezzat @DrBenUnderwood1 @NHSEngland @ObserverUK @DavidJonesBrain Agreed. I think recognizing mild behavioral impairment and SCI A+/T+ would need very close monitoring and increasing our awareness of early signs is important. If you tracked p217 increasing each year in such an individual that would be quite concerning: jamanetwork.com/journals/jaman…
Brilliant plenary lecture by Nick Ashton at @alzassociation #Tau2024 on past present and future of blood based biomarkers
‘Parties currently measuring Tau protein in relation to a neurological condition in a research or diagnostic setting on any other platform risk infringement of Quanterix’s intellectual property’ 🙃 businesswire.com/news/home/2024…’s-Disease-Testing-Infrastructure
Study found that a commercially available plasma p-tau217 immunoassay accurately identified biological Alzheimer disease, comparable with results using cerebrospinal fluid biomarkers, with reproducible cut-offs across cohorts. ja.ma/48O2KqD
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings | Nature Communications nature.com/articles/s4146…
And the brilliant @wagnersbrum strikes again 🧠👇👇🩸
And the brilliant @wagnersbrum strikes again 🧠👇👇🩸
Way to go @wagnersbrum ! Very relevant for reducing unnecessary tau-PET and improving patient management and reducing costs.
Way to go @wagnersbrum ! Very relevant for reducing unnecessary tau-PET and improving patient management and reducing costs.
Can we improve the prognostic work-up of patients with cognitive symptoms? In my experience, accurate prognostic information is important for many patients and tau-PET imaging is a powerful, but costly, tool. Here we show that triaging using plasma ptau217 can reduce need of PET.
Can we improve the prognostic work-up of patients with cognitive symptoms? In my experience, accurate prognostic information is important for many patients and tau-PET imaging is a powerful, but costly, tool. Here we show that triaging using plasma ptau217 can reduce need of PET.
“If we believe we can change things, we can. Everyone told me it would be hard to do high-quality research in my home country of Brazil. I saw an opportunity to help people in lower-income countries. My lab now has 37 students.” - @erzimmer, @ISTAART member, #ALZFunded…
Super happy to see this paper out!! Difficult to choose which one is the best, if any, but maybe you’ll pick your favourite? Take a look and let me know! 😊 Thank you for all giant researchers/colleagues/friends supporting us on this one again 💪🏻 @pedrorosaneto @NicholasAshton
Super happy to see this paper out!! Difficult to choose which one is the best, if any, but maybe you’ll pick your favourite? Take a look and let me know! 😊 Thank you for all giant researchers/colleagues/friends supporting us on this one again 💪🏻 @pedrorosaneto @NicholasAshton
Our new head-to-head comparison of the Janssen and Alzpath plasma p-tau217 assays is now published in @EmboMolMed Congratulations to @andrealessa on her first paper as a senior author! sciencedirect.com/science/articl…
Sacubitril/valsartan, compared with valsartan, increased plasma Aβ42 and Aβ40 levels, reducing Aβ42/Aβ40 by ~30%. Other AD plasma biomarkers were unaffected, suggesting patients taking the drug could be misdiagnosed as Aβ-positive by plasma Aβ blood tests. ja.ma/3uxbfIA
Check out the @alzforum commentary on our🩸NTA paper in : alzforum.org/news/research-…
Check out the @alzforum commentary on our🩸NTA paper in : alzforum.org/news/research-…
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247 Followers 268 Following Neurologist, Head of memory clinic, Bordeaux University Hospital. Associate Professor of Neurology, Bordeaux University, FranceAn interesting work by @JosephTherr @andrealessa as @eBioMedicine editor pick. Kudos to this great team!
Editor pick from April issue @JosephTherr @NicholasAshton @pedrorosaneto @andrealessa & coll Compared the performance of two commercially available plasma p-tau217 assays in 294 individuals with #Alzheimer's disease. Read bit.ly/4aLAGWN
Editor pick from April issue @JosephTherr @NicholasAshton @pedrorosaneto @andrealessa & coll Compared the performance of two commercially available plasma p-tau217 assays in 294 individuals with #Alzheimer's disease. Read bit.ly/4aLAGWN
Please provide input for Julie’s plenary talk covering an overview of past years’ neuroimaging papers! 👇(I already did)
I will present the @NeuroimagingPIA year in review talk at ✨AIC 2024✨in Philadelphia this July!🤩 many thanks to @alzassociation #AAIC24 🎖️ Please help me compile the most inspiring papers of the year (including your own research!) via this survey: 📨 forms.gle/jpcTygkvjd1XGi…
Amazing poster encouraging Japanese to emigrate to Brazil. Almost 250k would make the voyage from 1908 to 1984, making it the largest diaspora outside Japan
Rafael Borré nos últimos 5 jogos pelo @SCInternacional: ⚽️ 2 gols 🅰️ 1 assistência 🅿️ 3 participações em gols 💯 Nota Sofascore 6.96 📊 Entre todos os jogadores da Série A no período: 🥇 1º em finalizações (21) 🥇 1º em finalizações no gol (10) 🥇 1º em chances claras de gol…
"in absolute terms the small increment in mortality risk associated with clozapine due to agranulocytosis might be offset by its well known effects on symptom reduction and function" New research Article @JRubioMD thelancet.com/journals/lanps…
**MEMTAB 2025 confirmed!** Methods for Evaluating Models, Tests & Biomarkers Uni of Birmingham, UK, 29th April - 1st May 2025 29th April: pre-conference courses 30th April: conference day 1 & evening event 1st May: conference day 2 Save the date! Abstract call begins July 2024
e eu que mudei totalmente alguns hábitos de relacionamento por causa de um vídeo do tiktok
Exercise, strength training… start it now. Put muscle in the bank so you have a decent reserve when the aging process comes knocking. And when it knocks, fight back like your life depends on it.
In our new preprint, we measured frailty trajectories in the years preceding dementia to better understand the direction of that relationship. We report observational evidence that frailty increases dementia risk independently of reverse causality. researchsquare.com/article/rs-431…
@dudelbem Oi, Luiz, o caráter paroxístico é estereotipado dos eventos pede uma investigação detalhada quanto à possibilidade de crises focais de epilepsia, eventos vasculares (ex. AIT) e, se ela já for mais idosa, uma avaliação cognitiva detalhada. Em BH indico a @Elisa_Resende_
To authors, reviewers, editors, ghost writers and your native speaker cousin who goes over your manuscripts: Pretty please just use actual numbers in abstracts. There is no reason to say “large sample” when you can write “52” or “332” or “1241”. In fact you save 3 words.
Quarta feira eu estarei de novo no Beira Rio. Tomarei minha cerveja no Marinha antes do jogo e apoiarei o time os 90 minutos. Críticas ou vaias, se houver, no final do jogo. Cada um faz sua escolha. Há quem vaie o time com 10 minutos de jogo. É um direito. Mas acho uma pena.
Receiving the 'One to Watch' Award from @alzassociation in the same event that one of the scientists I most admire - @pedrorosaneto - wins the 'Excellence in Neuroscience Mentoring' Award is a unique & incredible feeling! I am so grateful for this moment!
Congratulations to @jpfsouza33 for receiving the #AAICNeuro 'One to Watch' Award, and congratulations to Prof. @pedrorosaneto for winning the @alzassociation 'Excellence in Neuroscience Mentoring' Award! 🏆 You both deserve it! 👏💜
Wondering if this is upregulated Glutamate receptor stage is a compensatory excitatory state before more rapid neuro degeneration occurs… @CorriveauNick 🤔
This study explores glutamate signaling in patients with Parkinson disease with REM sleep behavior disorder. Read the article: bit.ly/4aMzqTa
How the Red Hot Chili Peppers made the song “Snow”
Eriksen after his first week in Turkey.
🚨 Christian Eriksen is attracting interest from Turkey and will be allowed to leave Manchester United this summer. #MUFC [@MarkOgden_]
Getting a notification of a goal before you see it on your dodgy steam
Pensando aqueer…… q sdds de faze um xou………..produtores do rio grande do sul, parana e sao paulo kd vcs 👀👀👀