Nick Corriveau-Lecavalier, PhD @CorriveauNick
Neuropsychologist studying the degenerating mind at @MayoClinic @NaipMayo | Assistant Prof @MayoClinicNeuro & @MayoPsych researchgate.net/profile/Nick_C… Rochester, MN Joined July 2018-
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Yes, and we have shown that they produce AD-like tau-PET patterns neurology.org/doi/abs/10.121…
Yes, and we have shown that they produce AD-like tau-PET patterns neurology.org/doi/abs/10.121…
Only 100 pages in @yudapearl's "Book of Why" and it is already eye-opening. Always wanted to shy away from associations and move toward mechanisms, models, theory, and causality, but never really knew how. A must-read!
Matlab is the worst programming language. Sue me.
Me: Ever had thoughts that life is not worth living anymore and that you'd want to end it? Patient: I worked too hard to be alive to have such thoughts. Working with patients with cancer sure puts things in perspective
The lights are moving. If you move your fingers over the arrows, you'll still perceive movement.
The lights are moving. If you move your fingers over the arrows, you'll still perceive movement.
@AndrewK_PhD @VincentPlanche @MadhavThambiset @smead2 @SuzanneESchind1 @DrTFromKC @seb_walsh @pash22 @EWidera @ajlees @ProfRobHoward @MemoryDoc @dr_shibley @LonSchneiderMD @_michael_scholl @StefanoSensi14 @AlbertoEspay @nvillain_alz @KasperKepp @PhilAlz @Gill_Livingston @jfballenger @jasonkarlawish @JamesRuFletcher @AdamMBrickman @ManlyEpic @SFAckley @FortuneMagazine @TIME @ErinMPrater @TIMEMagazineRS @FT @hannahkuchler @CTADconference @NIH @alzassociation @howard_gleckman @AmerGeriatrics @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @US_FDA @NICEComms @RaymondKoopmans @MaastrichtU @Kariem_Ezzat @DrBenUnderwood1 @NHSEngland @ObserverUK This plot captures normal aging and the full spectrum of neurodegenerative conditions. The A+ orange dots are amyloid-PET positive and they occur everywhere across this spectrum.
Clinicopathologic Heterogeneity and Glial Activation Patterns in Alzheimer Disease #neuropath jamanetwork.com/journals/jaman…
Great meta-analysis showing biomarker odds ratio conversion rates from cognitively normal to MCI or dementia. A-,T+ OR ≠ sig A+,T- OR 2.04 A+,T+ OR 13.46 Older age A+ decreases odds ratio of conversion. alzres.biomedcentral.com/articles/10.11…
‼️ Postdoc ad // Please RT/circulate ‼️ Are you interested in * Big euroimaging and multi-omic data? * Neurodegenerativ disease? The @biofinder_study is looking for a talented postdoc to sink their teeth into some rare and exciting data! Apply here: lu.varbi.com/en/what:job/jo…
In relation to this study, my paper in Brain (1999) predates the JAMA reference of 2021, and which proposed for the first time the critical rôle of the ventromedial prefrontal cortex in decision-making abnormalities in bvFTD, ref: academic.oup.com/brain/article/…. @CorriveauNick @pash22
In relation to this study, my paper in Brain (1999) predates the JAMA reference of 2021, and which proposed for the first time the critical rôle of the ventromedial prefrontal cortex in decision-making abnormalities in bvFTD, ref: academic.oup.com/brain/article/…. @CorriveauNick @pash22
Group-wise comparisons of FDG-PET hypometabolism: Pair-wise comparisons between each patient group and cognitively unimpaired controls matched for sample size, age and sex. Great work by @CorriveauNick
Group-wise comparisons of FDG-PET hypometabolism: Pair-wise comparisons between each patient group and cognitively unimpaired controls matched for sample size, age and sex. Great work by @CorriveauNick https://t.co/4dGv6QMlzE
@PhilAlz @MadhavThambiset @EWidera @smead2 @ajlees @ProfRobHoward @MemoryDoc @dr_shibley @LonSchneiderMD @seb_walsh @_michael_scholl @VincentPlanche @StefanoSensi14 @AlbertoEspay @nvillain_alz @KasperKepp @Gill_Livingston @DrTFromKC @jfballenger @jasonkarlawish @JamesRuFletcher @AdamMBrickman @ManlyEpic @SFAckley @FortuneMagazine @TIME @ErinMPrater @TIMEMagazineRS @FT @hannahkuchler @CTADconference @NIH @alzassociation @howard_gleckman @AmerGeriatrics @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @US_FDA @NICEComms @RaymondKoopmans @MaastrichtU @Kariem_Ezzat @DrBenUnderwood1 @NHSEngland @ObserverUK @FeiiXiong @kzotcheva Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases academic.oup.com/brain/article/… via @CorriveauNick et al
It's me!
Corriveau-Lecavalier et al. show that dementia syndromes targeting executive functions have different signatures of brain degeneration to those affecting personality and behaviour, with implications for diagnosis and symptom management. tinyurl.com/5n8prmbx
Probably too late to ask but what do we mean by "emergeant property" from a neurscience perspective?
Took a decently long break from Twitter but the truth is that, even if this platform is nowhere near what it used to be, I missed the connections and learning opportunities. Screw Elon nonetheless
***Hot off the @JAMANeuro e-press*** While seeking to investigate clinicopathologic heterogeneity and glial activation patterns of #Alzheimers...we created a corticolimbic index (CLix) to better capture the individuality of tangle distribution. jamanetwork.com/journals/jaman…
🚨Paper Alert🚨 Excited to share our new piece with @MichalonRobin from @EHESS_fr @CAK_UMR While debates rage on following @alzassociation new #Alzheimer’s criteria we propose (Open Access) a historical perspective on what Alzheimer’s is. A thread👇🏻 1/21 onlinelibrary.wiley.com/doi/10.1111/en…
Prof. Melissa E. Murr.. @DrNeuroChic
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@CorriveauNick Thank you for sharing. It's a different perspective than one I usually hear (some neuroscientists I speak with say MATLAB too simplistic, albeit often not being aware of the full language). All perspectives matter & I appreciate to know yours!
@CorriveauNick I use MATLAB for the same reason that I’ve never signed up for the TSA PreCheck line I’m lazy, I never know what’s going on, and plenty of people seem to be getting along fine without switching over But man am I jealous watching those who did keep their shoes on…
A 41 year old man comes in for help with headache He’s had 5-6 severe headaches/month for years, but over the last 6 months has had daily, bifrontal, throbbing headaches Each month he takes: Acetaminophen ~10 days Ibuprofen ~9 days Sumatriptan 6-7 days What do you tell him?
@SimonJodoin Mais s’il fait ce que vous dites, il n’a plus de carrière
The struggle for moral superiority in the field of mental health is striking. It's embedded in a culture of moral Darwinism, driven by economic & social incentives. The moral show off may seem effective, yet it often falls short, as people require solutions beyond mere posturing
Wondering if this is upregulated Glutamate receptor stage is a compensatory excitatory state before more rapid neuro degeneration occurs… @CorriveauNick 🤔
This study explores glutamate signaling in patients with Parkinson disease with REM sleep behavior disorder. Read the article: bit.ly/4aMzqTa
Worst change ever!
A white cloud enjoying the wind as the storms start to form
@CorriveauNick @smead2 @MadhavThambiset @dcweisman @pash22 @AANmember Absolutely. The “time savings” arguments are not robustly supported by the trial data and are false promises that patients and families understandably latch onto. We have to be so careful if we want patients to make informed risk:benefit decisions about treatment.
@CorriveauNick @smead2 @dcweisman @ProfRobHoward @pash22 @AANmember The can-drive-longer is identical to the claim that treated patients avoid nursing home placement for six months longer than those on placebo. These outcomes were not tested in the trials & to suggest that these benefits result from Rx is misguided at best, misleading at worst
@smead2 @ProfRobHoward @pash22 Is there an item on the CDR SOB that assesses your ability to drive a car?
@neuroblues7 La próxima vez, pregúntale a la persona si puedes usar su imagen y no se lo digas después de robarla. Palabra que usaste tú mismo. Podrías haber editado tu publicación para agregar mi nombre más tarde también, te habría tomado 5 segundos. Pero no quieres compartir me gusta y…
@neuroblues7 Please give me credit for my image.
@DrKentris @MattiaRosso3 Eternal sunshine of the spotless mind is one of my favorites.
Happy to share our paper on atrophy heterogeneity in memory clinic settings – now online @Brain1878! This was a big one (started working on this on the first day of my PhD 👀), so let me walk you through it 🧵 [1/n] tinyurl.com/subtypesNstages @DZNE_en @biofinder_study @david_berron
Words are not enough to describe what @pedrorosaneto did and does for his/her mentees! Congratulations, @pedrorosaneto!
Congratulations to @pedrorosaneto for winning the Alzheimer's Association "Excellence in Neuroscience Mentoring" Award! Anyone would be lucky to have you as a mentor and I am so grateful to be one of the lucky ones 🥹🎉 @alzassociation