Alzforum @alzforum
A news and information resource website helping scientists advance AD research since 1996. Alzforum doesn’t endorse any specific product or scientific approach. alzforum.org Boston, MA Joined August 2009-
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Without γ-secretase, APP C-terminal fragments accumulate in lysosomes, blocking influx of calcium from the endoplasmic reticulum. @KU_Leuven ow.ly/i4Za50RpWa9
In amyloidosis mice, some TREM2-positive microglia become senescent and harm the brain. #alzheimersdisease @WeizmannScience ow.ly/uQNS50RpJW9
In neurons, lysosomes transport certain mRNAs into axons, maintaining ribosomal and mitochondrial function in these synaptic hot spots. @NIH ow.ly/pYHW50RpocO
The GLP-1 analogue lixisenatide helped Parkinson’s patients in a small Phase 2 trial maintain their motor abilities over one year. #parkinsonsdisease @Univ_Toulouse ow.ly/aCPk50Rocae
A new p-Tau212 assay shows promise as a plasma biomarker of #alzheimersdisease, rivaling the performance of p-Tau217. @goteborgsuni ow.ly/kWKk50RktPT
Peptides possess the power to spark propagation of tau fibrils, or to dismantle fibrils entirely. Two studies point to therapeutic strategies for tauopathies. @ucsantabarbara @UCLA ow.ly/fGY750RkjcX
At #ADPD, scientists showcased preclinical efforts to target microglia in AD, by activating TREM2, blocking CD33, and stopping ASC specks. @adpdnet ow.ly/EnVX50Rk9t3
At #ADPD, scientists parsed microglial and astrocytic contributions to AD pathophysiology. Microglia change their tune as disease worsens. @adpdnet ow.ly/3rh850RftJN
Sumoylation influences tau phosphorylation and aggregation, with SUMO1 promoting, and SUMO2 preventing, these processes. #alzheimersdisease @adpdnet @Columbia @MarioNegriIRCCS @UofT ow.ly/87NR50Rfh1v
Microglia expressing the inhibitory receptor LILRB4 laze around plaques in #Alzheimersdisease and amyloidosis mice. An antibody against LILRB4 stirred microglia to engulf Aβ fibrils and lower plaque load. @WUSTL ow.ly/7zvU50RexJh
A p-tau217 antibody reduced tangles and neurodegeneration and improved memory and coordination in mice. It, and another antibody targeting N-terminal tau, restored brain proteostasis to wild-type levels. @xmuchina @UQ_News ow.ly/1CGt50Remw7
Researchers at AD/PD 2024 discussed progress in developing disease-modifying therapies for synucleinopathies. #parkinsonsdisease @adpdnet ow.ly/sPMC50RcMUi
At #ADPD, scientists focused less on how tau travels between cells, and more on what happens after it arrives. Mechanisms include seed triage by an ATPase and vesicular packaging. @adpdnet ow.ly/NWxh50R7Y6s
Punch biopsies measuring the amount of phosphorylated α-synuclein in the skin diagnosed four synucleinopathies with 93 to 100 percent accuracy. @harvardmed ow.ly/rZCt50R6JVH
Researchers at AD/PD 2024 presented new mouse models of CAA and ARIA, and proposed potential biomarkers of the former and treatments for the latter. #alzheimersdisease @Radboud_Uni @UABBarcelona @adpdnet ow.ly/2XZi50R4Cyl
Scientists linked genetic variants to age-related changes in expression of 10,000 genes in different brain cell types and subtypes. One variant increased expression of APOE only in microglia and correlated with worse CAA. #Alzheimersdisease. @Columbia ow.ly/p8xf50R3v0M
MRI shows CSF flowing into the brain by hugging cerebral arteries. It rides their pulses, spreading into cortical tissue along the way. The data supports the existence of a human glymphatic system. @Oslounivsykehus ow.ly/oaJm50R2wN0
ADPD 2024 highlights O-GlcNAcase inhibitors’ push toward Phase 2 trials in tauopathies. Preclinical studies broaden tau immunotherapy strategies. @adpdnet ow.ly/vefn50R0qee
Despite another Phase 3 flop, TauRx leveraged subgroup analyses to claim glimmers of efficacy for the methylene blue derivative, HMTM. @TauRx @adpdnet ow.ly/6ueN50R0eZw
Knocking out TREM1 preserved memory in old wild-type mice and in models of amyloidosis. Myeloid cell and neuron metabolism improved, while microglia remained ramified. @Stanford ow.ly/thnh50QZ5zG
Prof. Melissa E. Murr.. @DrNeuroChic
5K Followers 1K Following Translational neuropathologist | Biomarker enthusiast | Hopeful scientist | Scientific Program Committee @HAIconference #AAIC24 | Advisory board #ADPD2025John Lukens @LukensJohnR
11K Followers 3K Following Neuroimmunologist studying MS, autism, Alzheimer's disease, and brain injury at the University of Virginia. Father of two. Fan of Philly sports and US soccer.Celeste Karch @karchlab
4K Followers 364 Following Professor. Washington University School of Medicine. Genomics, stem cell models, molecular mechanisms of AD and other tauopathies. She/her.Rachel Buckley 🐨�.. @bucklr01
5K Followers 2K Following Assistant Professor @ MGH/Harvard Med: sex differences in risk for preclinical AD. K99/R00 and DP2 awardee. Co-PI of @healthybrain_au. Aussie. Twin mumProf Selina Wray @SelinaWray
12K Followers 3K Following Professor of Molecular Neuroscience at UCL Queen Square Institute of Neurology. Barnsley lass. she/her @wraylabUCL @UCLIoNShane Liddelow 🍊 @LiddelowSA
12K Followers 732 Following Neuroscientist and glia aficionado @nyulangone, @nyugrossman, @NYULH_Neuro Tweets in my individual/personal capacity. he/himDr. Malu Tansey @MaluTansey
7K Followers 5K Following Stanford, UTSW, Latina, mother, daughter. Immunity inflammation lysosomes neuroimmuno neurodegen, EIC NPJPARKD, Prof, Parkinson’s GRC Chair 2023. Tweets my own.Prof Tara Spires-Jone.. @TSpiresJones
8K Followers 4K Following Neuroscientist. Prof @EdinburghUni Group Leader @UKDRI founding editor @BrainComms President @BritishNeuro (you can call me madame president). she/her 🧠 🔬 📚ShorterLab @ShorterLab
11K Followers 6K Following Countering deleterious phase transitions in ALS/FTD, PD, AD, and related disorders @Penn @PennMedicine @bb_upenn @BMBGGUPENN @PGGUPenn @PennNGG @CAMBUpennUK Dementia Research .. @UKDRI
13K Followers 1K Following New scientific discoveries, new hope to stop dementia. Founding funders: @The_MRC @alzheimerssoc @AlzResearchUKNat Rev Neurology @NatRevNeurol
45K Followers 196 Following Nature Reviews Neurology is a clinical review journal from Springer Nature. Follow us for the latest updates in neurology from the journal and beyond.RikOssenkoppele @RikOssenkoppele
4K Followers 198 Following Neuroscientist | Alzheimer's disease | PET, MRI, fluid biomarkers | Cognition | Associate Professor @AlzheimerAms & @lunduniversityShannon Macauley @macauleylab
4K Followers 2K Following Associate Prof, PhD, wife, mom. Alzheimer’s disease | diabetes | brain metabolism | sleep | I ❤️ lactate | lysosomal storage diseases | she/herYakeel T. Quiroz, PhD.. @ytquiroz
9K Followers 2K Following Associate Prof @HarvardMed @MassGeneralNews MGH Research Scholar | Director, Familial Dementia Neuro Lab @MGHmapp @MGHmarc #COLBOS #BLASTbio Views=Own | Feb’18Molecular Neurodegene.. @MolNeuro
3K Followers 758 Following The top ranked open-access neuroscience peer-reviewed journal with a 2022 Impact Factor of 15.1. Official journal of @_BrightFocusNick Corriveau-Lecava.. @CorriveauNick
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2K Followers 807 Following Neuroscientist in Dementia / University of Gothenburg 🇸🇪 / King's College London 🇬🇧 / Centre for Age-Related Medicine 🇳🇴CTAD @CTADconference
3K Followers 368 Following The Clinical Trials on Alzheimer's Disease conference (CTAD) is a meeting focused entirely on Alzheimer’s Disease Therapeutic TrialsMaria Teresa Ferretti @MaTeFerretti
3K Followers 4K Following Neuroscientist, brain health advocate, editor, cancer survivor, TED-x speaker, author. Anything related to the brain interests me–but #Alzheimer is my passionGan Lab @LiGanLab
4K Followers 577 Following Group of enthusiastic scientists studying how maladaptive immune responses and mishandling of proteins contribute to Alzheimer's disease. Managed by lab membersSemanti Chakraborty @SemantiCh29
106 Followers 340 Following Biotechnology MS Junior Research fellow Molecular Neurobiology @presidencyuniversity Podcast https://t.co/ZHP9dfS4HwMd Mohsin Ali @mohsinbg12027
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14 Followers 104 FollowingJonathan Barra @jonathanbarrac
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1K Followers 3K Following 徐会文, Health Services Researcher, Assist Prof @UTMB_SPPH | Pepper Scholar @UTMB_SCOA. PhD @UofR. Funded by @NIHAging. @CHPAMS #Aging #LTC #ADRD #AI Twitter=MinesShreya @aspirantH3
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33 Followers 438 Following I am an academic clinical lecturer and specialist registrar doctor in neurology. My research focuses on helping people with epilepsy.Dapi Chiang @Dapi_Chiang
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4 Followers 146 FollowingLeighton Nasir @LeightonNa54512
31 Followers 621 FollowingChris Street🇬🇧M.. @ChrisGStreet
773 Followers 2K Following Retired maths & science tutor, MSc MedChem (Alzheimer's secretase drugs)Butch Whitton @butchwhitton
71 Followers 95 FollowingDev Patel @smoothbrain22
110 Followers 1K FollowingSaikat Ghosh @SaikatSls
532 Followers 915 Following Interested in intracellular trafficking, lysosome, iPSC, Neuronal Cell Biology and Microscopy. @ Bonifacino Lab, NICHD, NIH #Alumni @IISER MohaliAli Shojaie @AliShojaie_KCL
76 Followers 132 Following Ali Shojaie MD,MSc,PhD Maurice Wohl Clinical Neurosciene Institute King's College LondonStefano Cacciatore, M.. @stecacMD
922 Followers 3K Following Your friendly neighborhood geriatrician | MD @unicatt | #Sarcopenia, #Nutrition, #Frailty | SoME @GeriSocIta | Class of 2024 @scuolapoliticheKevin H @tweetkevinhuang
11 Followers 279 FollowingWegrzynowicz Lab @Wgrznwcz_lab
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224 Followers 3K Following offer vitamins and supplements https://t.co/6lX91v1au9 https://t.co/zo3V69PMED https://t.co/sQmtttMy3w https://t.co/4AsuEubyqN https://t.co/wNZJnwTH4t https://t.co/QTd4LCNYKe https://t.co/tlG6l5uHd5 https://t.co/P7PbTJ3ntJ 🌱Dr. Madhu Benekareddy @madhurimabr
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56 Followers 485 FollowingSirago Spanou @SiragoSpan32284
1 Followers 24 Following PhD candidate, Neural Stem Cells biologist in Neurodegenerative diseases, Microglia, Neuroinflammation @IMBB_FORTHJim Pittman @PittMarcom
241 Followers 3K Following Opinions expressed on this platform are ALWAYS strictly my own.Junping Pan @JunpingPan
6 Followers 92 FollowingKim Farinsky @kimbafar
68 Followers 604 FollowingMarie_Janes @Marie_Janes_
65 Followers 134 Following #dementiaresearch | @trentuni | @NIHRCRNEastMids | Hardcore @PanthersIHC fan | Polyglot | Lazy Twitter user - Views are my ownNIDUS Delirium Networ.. @NIDUS_Delirium
4K Followers 3K Following Network for Investigation of Delirium: Unifying Scientists (R33AG071744). Collaborative network developing resources to enhance #delirium research worldwide.Andrew Shaw @AndrewShaw85505
63 Followers 758 Following Assistant Professor of Toxicology at Heriot-Watt University. Interested in NO-redox biology, immunometabolism, & neurobehavioral disorders. Views are my own.Vindhya Vishwanath @Vindhya_217
18 Followers 208 Following ψ | Research Fellow @CBR_IISc | MS Clinical Psychology'23 @MAHE_ManipalFrancis @francishe99
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0 Followers 10 Following Senior laboratory technologist in the American university in cairo- Institute of Global health and human ecologyDavid Almog @davidalmog25
2K Followers 2K Following Managerial Economics and Strategy Ph.D. student @KelloggSchool • Behavioral and Experimental Economics • AI-Human interactions • LV Raiders • BackpackingAnnalsofHumanBiology @AnnalsHumanBio
307 Followers 270 Following Official Twitter for Annals of Human Biology Journal Affiliated with @SocStudyHumBiol Editorial Board: https://t.co/fTy7Ahq85QChaitali Anand @Chaitali_Anand
57 Followers 187 Following Translational Neuroscience PhD. Cognitive aging, functional magnetic resonance spectroscopy, Alzheimer's disease. 🧠🐕🏃🏻♀️📷🎨🖌️Rich @RichZitani
215 Followers 2K FollowingMarina Q - @MarinaQ24908672
6K Followers 715 Following Feminista da área jurídica. Sempre pela esquerda. Amante de viagens que não sabe cozinhar. Apaixonada por praia 🏝️ 🍀🏝️❤️❤️❤️❤️ام ميس @a_sumaih1445
4 Followers 60 FollowingTomás León @squallchileno
583 Followers 1K Following Geek. Chilean Psychiatrist 🇨🇱 GBHI Fellow. Unidad de memoria Hospital del Salvador.Celeste Karch @karchlab
4K Followers 364 Following Professor. Washington University School of Medicine. Genomics, stem cell models, molecular mechanisms of AD and other tauopathies. She/her.Rachel Buckley 🐨�.. @bucklr01
5K Followers 2K Following Assistant Professor @ MGH/Harvard Med: sex differences in risk for preclinical AD. K99/R00 and DP2 awardee. Co-PI of @healthybrain_au. Aussie. Twin mumProf Selina Wray @SelinaWray
12K Followers 3K Following Professor of Molecular Neuroscience at UCL Queen Square Institute of Neurology. Barnsley lass. she/her @wraylabUCL @UCLIoNShane Liddelow 🍊 @LiddelowSA
12K Followers 732 Following Neuroscientist and glia aficionado @nyulangone, @nyugrossman, @NYULH_Neuro Tweets in my individual/personal capacity. he/himProf Tara Spires-Jone.. @TSpiresJones
8K Followers 4K Following Neuroscientist. Prof @EdinburghUni Group Leader @UKDRI founding editor @BrainComms President @BritishNeuro (you can call me madame president). she/her 🧠 🔬 📚UK Dementia Research .. @UKDRI
13K Followers 1K Following New scientific discoveries, new hope to stop dementia. Founding funders: @The_MRC @alzheimerssoc @AlzResearchUKNat Rev Neurology @NatRevNeurol
45K Followers 196 Following Nature Reviews Neurology is a clinical review journal from Springer Nature. Follow us for the latest updates in neurology from the journal and beyond.RikOssenkoppele @RikOssenkoppele
4K Followers 198 Following Neuroscientist | Alzheimer's disease | PET, MRI, fluid biomarkers | Cognition | Associate Professor @AlzheimerAms & @lunduniversityYakeel T. Quiroz, PhD.. @ytquiroz
9K Followers 2K Following Associate Prof @HarvardMed @MassGeneralNews MGH Research Scholar | Director, Familial Dementia Neuro Lab @MGHmapp @MGHmarc #COLBOS #BLASTbio Views=Own | Feb’18CTAD @CTADconference
3K Followers 368 Following The Clinical Trials on Alzheimer's Disease conference (CTAD) is a meeting focused entirely on Alzheimer’s Disease Therapeutic Trialsbeth stevens @stevens1lab
15K Followers 2K Following Neuroscientist studying Glia, Synapses, and Neural - immune interactions; Alzheimer’s disease ; Open Science;UCSF MAC @UCSFmac
6K Followers 1K Following The UCSF Memory and Aging Center cares for people with, researches the causes/cures for, and educates people about degenerative brain diseases. #NIAfundedADRCNico Franzmeier @nfranzme
2K Followers 1K Following Neuroimaging Researcher | LMU Munich | Institute for Stroke and Dementia Research | studying tau spreading & resilience in Alzheimer's disease @ISDneuroimagingAdam Smith @BetterResearch
12K Followers 4K Following #Dementia Research at @UCL - creator of Dementia Researcher supporting ECR CareersDavid Gate @DGateLab
3K Followers 2K Following Assistant Professor, Northwestern Neurology. The Gate lab studies the role of the immune system in neurodegenerative diseases.Carlos Cruchaga @ccrugom
1K Followers 341 Following NeuroGenomics and Informatics Center Director. Washington University School of MedicineAD/PD - Advances in S.. @adpdnet
4K Followers 1K Following AD/PD™ 2024: Striving for a better future for all those affected by neurodegenerative diseases. March 5-9, 2024 | Lisbon, Portugal | #ADPD2024Lance Johnson @LJohnsonLab
2K Followers 532 Following Studying brain metabolism, Alzheimer's Disease, glia & all things APOE. opinions are my own (but I feel like they are quite good)VIB-KU Leuven Center .. @CBD_VIB
3K Followers 361 Following Neuroscience center in Belgium 🔬🧠 Part of @VIBLifeSciences × @KU_Leuven ✨ Discover our research community ➡️ https://t.co/oDhNWj4ixQSalk Institute @salkinstitute
39K Followers 4K Following The Salk Institute for Biological Studies is one of the world's preeminent basic research institutions. Click link below to sign up for our monthly newsletter.C Van Broeckhoven @cvbroeck
2 Followers 17 FollowingAlzheimer's Afternoon.. @AlzAfternoons
859 Followers 2 Following Alzheimer's Afternoons seminar series. Every Tuesday and Thursday 3pm EDT. On Friday we have our Happy hour with two talks from trainees.HenneHolstege @HolstegeHenne
640 Followers 204 Following cognitively healthy centenarians escaped dementia: it’s in their genome! #100plusStudy @AlzheimerAms @amsterdamumc @GeneticAms @AmsNeuroscience https://t.co/o04nvzjb6cThe Rainwater Charita.. @RCFNeuro
888 Followers 422 Following Supporting scientific progress to understand primary tauopathies in neurodegenerative disease research. Visit our website to discover all our funding programs.C. Roy Lin, MD MPH @RoyCLinMD
2K Followers 980 Following @BCMHouston neurologist | Director, @CurePSP Center of Care @PDCMDC | #Cerebellum ↔️ Behavioral neurology investigator 🧠🇺🇸🇹🇼🏳️🌈Lisa S. Robison, PhD @LisaRobison86
690 Followers 1K Following @NSUFlorida educator & neuroscientist. Lifestyle factors and repurposed meds in dementia. She/her.Emily Berkowitz @emberko
356 Followers 2K Following #PR & #Communications at @TheADDF | Previously @nyphospital & @joslindiabetes | Feminist | Chocolate connoisseur | Doodle enthusiast | Tweets are my own.Dr. Jennifer Manly @ManlyEpic
6K Followers 2K Following #neuropsychologist #healthequity #SDOH #brainhealth #AD @Columbia. Posts represent my personal views and not those of CUIMCWray Lab @WrayLabUCL
2K Followers 506 Following Research group in the Department of Neurodegenerative Disease @UCLIoN working on Alzheimer's Disease and Frontotemporal Dementia.Maria Carrillo @DrMariaALZ
4K Followers 340 FollowingBernadette Keefe MD @nxtstop1
23K Followers 10K Following MD; Curator:Medical/Health/Tech; Focus: Aging, Mobility, AgingTech, AgeTech, HealthyAging, AssistiveDevices, AssistiveTechJason Resendez @jason_r_DC
5K Followers 4K Following President & CEO of @NA4Caregiving. Felix’s dad. Former @UsAgainstAlz @WeAreUnidosUS @LULAC. @Georgetown Hoya. South Texan in DC. Opinions mine.Prof Clive Ballard @Clive_Ballard
3K Followers 2K Following Dean @UniofExeter Med School. Researching #dementia incl. prevention, care & treatment, Lewy bodies, Parkinson's. Ageing runner. #ExeterDementia #AlzheimersAnirudh Jaisimha @anirudh_v_jai
168 Followers 476 Following Industry Scientist. Lapsed researcher with a keen interest in cell-biology, neurodegeneration.jeremy freeman @thefreemanlab
5K Followers 3K Following executive director @carbonplanorg. previously: neuroscience and computational biology. open source, open science, collaboration. (he/him)Wellcome @wellcometrust
224K Followers 2K Following Supporting research to transform life, health and wellbeing. We’re taking on three urgent health challenges: mental health, climate change & infectious disease.CZI Science @cziscience
27K Followers 573 Following Supporting the science and technology that will make it possible to cure, prevent, or manage all disease by the end of the century.Gates Foundation @gatesfoundation
2.1M Followers 1K Following Partners of Human Potential | When you get the right partners together, the potential is endless.Bill Gates @BillGates
64.6M Followers 586 Following Sharing things I'm learning through my foundation work and other interests.I have left this plat.. @balbensi
2K Followers 5K FollowingDr. Carrie Esopenko @cesopenko
1K Followers 710 Following 🇨🇦 Import. Associate Professor @SinaiTBI || Studies brain injuries & mental health in #IPV & #athletes || PI @enigmabrains IPV Working Grp || Views are my ownConnie Corley PhD @loveviralnow
277 Followers 762 Following Faculty at Fielding Graduate U &Cal State LA (Emeriti). Proud mother of 2 daughters. Host of Love Goes Viral Apple podcast and https://t.co/DI1RuKZUHimartin rossor @martinrossor
3K Followers 520 Following NIHR National Director for Dementia Research, Professor Emeritus, and Principal Research Associate at the UCL Queen Square Institute of Neurology.Wes Ashford @wes_ashford
105 Followers 222 Following Stanford Professor, Neuroscientist, Neuropsychiatrist. Longtime leader in Alzheimer's Research.Mychael Lourenco @mvlourenco
3K Followers 2K Following Neuroscientist studying molecular mechanisms of Alzheimer’s disease and related disorders. Assistant Professor at @UFRJ.Dr Nik Sharma @DrNikSharma
2K Followers 2K Following CEO & Co-Founder @ BioCorteX and Neurologist #microbiomeDavid Berron @david_berron
2K Followers 1K Following Cognitive neuroscientist | Group Leader @DZNE_de & @biofinder_study | memory | alzheimer | digital health | co-founder @neotiv_app | @davidberron.bsky.socialLon S. Schneider, MD @LonSchneiderMD
2K Followers 472 Following University of Southern California, Alzheimer Disease Research CenterJin-Tai Yu, MD, PhD @JinTaiYuUCSF
526 Followers 2K Following Neurologist; Scientist; Geneticist; Alzheimer's Research; Dementia; PSP; Precision Medicine; Tauopathy; Neuroimaging; Biomarker; GWAS; MRICaroline Cicero @CarolineCicero
2K Followers 4K Following Urban Gerontologist; USC Prof; Advocate for Aging, Health, Design, & Lifespan Cities; USC Age Friendly University Initiative; USC Emeriti CenterPat Kehoe @ProfPatKehoe
514 Followers 214 Following Bench to bedside Translational Dementia Research on mechanisms linking vascular dysfunction & dementia to find new treatments. VIEWS OWN ♻️🇮🇪🇪🇺Dr Audrey Gabelle @DrAudreyGabelle
474 Followers 487 Following #Neurologist, Associate Professor, M.D and PhD. Head of the #Memory Center of #Montpellier #university #hospital #France #Alzheimer #DementiaDiego Forero MD, PhD @daforerog
2K Followers 5K Following Neuropsychiatric genetics. Researcher, Fundación Universitaria del Área Andina. Editor, American Journal of Medical Genetics B, BMC Research Notes and PLOS OneHowell Lab @GHowell_Lab
904 Followers 446 Following We use genetics and genomics to understand neurodegenerative diseases. We also use modern approaches to develop more predictive models for Alzheimer's disease.Vandenbroucke lab @Vdb_lab
750 Followers 291 Following Research field: Gut and brain barriers in inflammatory diseases @UGent @VIBLifeSciences @InflamResCen. Headed by @vdb_RoosDr. Stephen Haggarty @neuro_mgh
1K Followers 3K Following Professor, Neuroscientist | Neuropharmacology, Neuroplasticity, Epigenetics & MoleculesJulien Muffat @tinyglue
1K Followers 2K Following Canada Chair in Synthetic Neuroimmunology at the Hospital for Sick Children and the University of Toronto, Tech Geek, Science Nerd, Frenchy, Happy DadInstitute for Neurode.. @INDUCSF
539 Followers 469 Following We are the Institute for Neurodegenerative Diseases @UCSF—Discovering therapies to treat brain diseases such as #CJD, #Alzheimer, #Parkinson, and #dementiaDr. Emily A. Aery Jon.. @EmilyAeryJones
2K Followers 1K Following Postdoc studying spatial memory 🐭🧠 @Stanford | NINDS #Alzheimers K99 awardee | interneuron enthusiast, sharp-wave ripple lover & code junkie | she/herNidaa Anwar Ababneh �.. @Nidaa_Ababneh
110 Followers 923 Following 🇯🇴🇬🇧 Interested in inherited rare diseases, stem cells and gene editing research @jordanuni_int; @UCL; @IoOECREdinburgh Dementia Pr.. @CenDemPrevent
2K Followers 477 Following A cross-discipline research centre established to understand and tackle risk factors associated with dementia. Directed by Profs Manson, Ritchie and Clarke.Mike Donohue @MikeCDonohue
125 Followers 140 Following Associate Director of Biostatistics at Alzheimer's Therapeutic Research Institute of University of Southern CaliforniaHeather Brown @heatherjyb
18 Followers 74 Following I'm an editor @TheLancetNeuro and I knit whenever I'm able. If I get round to expressing any views here, they will be my own.@alzforum @Alzheimers_NIH @WakeForest Hi @alzforum, NIA has updated its Twitter handle! Please use @NIHAging moving forward so we can see your tweets! 😀
I was asked to contribute to some work summarizing Tau-targeting therapies. I still can not believe how good of a resource @alzforum is. The amount of information is incredible, and all up to date. Can't imagine how many work-hours the collective AD-field owes alzforum.
Always a pleasure to contribute @alzforum 😀 alzforum.org/papers/plasma-…
Preprint describing a coordinated approach by public domain bioinformatics resources curating proteins relevant to Alzheimer Disease content.iospress.com/articles/journ… #Alzheimers @Alzheimers_NIH @aruk @aruknew @UCLgene @imexconsortium @QuickGO_EBI @uniprot @alzforum @complexportal
…and finally, for news and updates on the latest research into dementia, check out: Neurocentral - @Neuro_Central Alzforum - @alzforum Add your suggestions for great accounts in the replies below ⬇️⬇️⬇️
Check out the Alzforum coverage on our recent paper on maintained cognitive health in centenarians. We can learn so much from them! alzforum.org/news/research-…
Amyloid and PET #imaging reveals the pathology driving particular #Alzheimers disease symptoms alzforum.org/news/conferenc… MT @alzforum #neuroscience #dementia @YuHelenYu @RonniLaurie @MairiLicious7 @RodneyClaeys @DrWardBondTV @IrmaRaste @KentSmalley @b_and_s_designs @Neil_ODonnell
The first ever Tau2020 Global Conference was a big success. Thanks to @alzforum for a nice summary.
A new international tau meeting kicked off in Washington, D.C. It aims to cover all tau-related diseases. Researchers reported new genetic variants for progression of progressive supranuclear palsy and Parkinson’s disease. #Tau2020 ow.ly/8sVd50yCdo2
Here is Part 2 of Alzforum’s excellent write-up of the Tau2020 Global Conference.
Scientists have solved the three-dimensional structure of α-synuclein fibrils isolated from diseased human brain. They look different than tau fibrils. @MRC_LMB #Alzforum ow.ly/V19o50yDfmd
Summary & discussion covering our recent work into cognitive maintenance in centenarians ja.ma/2VNefwO. @AlzheimerAms @AmsNeuroscience @VU_FGB @VUamsterdam @HenneHolstege #NinaBeker
Dutch study: If you are still sharp at 100, you’ll stay sharp and healthy some years longer. Such people offer a way to identify protective factors against #alzheimersdisease. #vrijeuniversiteitamsterdam ow.ly/UVqF50yDcwR
It's fantastic to see @alzforum write about our @biorxivpreprint on #alphasynuclein filaments from #MSA brains. The preprint model will only work if their precedence is properly recognized. alzforum.org/news/conferenc…
This is really cool
Scientists have solved the three-dimensional structure of α-synuclein fibrils isolated from diseased human brain. They look different than tau fibrils. @MRC_LMB #Alzforum ow.ly/V19o50yDfmd
Can PET Match Up Areas of Protein Deposit With #Alzheimers Symptoms? Read more at @alzforum: ow.ly/X2cZ50yCGSp #tangles #protein
Cool research identifying the "rhinal cortex" as the location of earliest tau deposits that are easily detectable using PET. Rhinal cortex surrounds the rhinal sulcus - the anterior part of the collateral sulcus that separates the entorhinal cortex from the fusiform gyrus.
Using PET, researchers detect first traces of tau accumulation in the rhinal sulcus, and propose a tau staging scheme. #Tau2020 #Alzforum ow.ly/lcNB50yEeRS
Great summary of tau PET tracer discussions that took place at The Tau2020 Global Conference.
Autopsy data confirms selectivity of different PET ligands for specific forms of tau. New tracers may specifically bind 4R tau and α-synuclein. #Tau2020 #Alzforum ow.ly/ZUFv50yF6Wf
This is very cool research! 👍🏼 #TAU2020 @KosikLab @MGHmapp @ApoEdscvr
Scientists identify a cell-surface receptor, LRP1, that binds tau, facilitating its spread through the brain. #Tau2020 #Alzforum ow.ly/ZVHG50yFWDi
Cool. Rauch found that LRP1 KD totally abolished tau uptake. Without LRP1, the H4 cells were unable to absorb monomers, oligomers, and fibrils of tau. Likewise, when LRP1 was KD in neurons derived from human induced pluripotent stem cells, they also no longer endocytosed Tau”
Scientists identify a cell-surface receptor, LRP1, that binds tau, facilitating its spread through the brain. #Tau2020 #Alzforum ow.ly/ZVHG50yFWDi
Behold the First Human α-Synuclein CryoEM Fibril Structure alzforum.org/news/conferenc… @alzforum
I always enjoyed the #Alzheimers mutations diagrams of @alzforum. Glad to see the update!
Alzforum unveils upgraded mutation diagram of key #Alzheimer’s protein APP. ow.ly/P3KR50yc52Q