Patrick Griffin @patrick_griffN
Postdoc @ Harvard HSCRB and the Broad Institute. Boston, MA Joined July 2012-
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Infinite Epigenetics & True Diagnostics acquire @sinclairfriends lab spin-out, Tally, giving them access to DNAme IP to help bring down costs & accelerate epigenetics-informed health care Congrats to @L_Catterton, @melanie_goldey, @patrick_griffN, @gladyshev_lab & the entire team! 👏
It takes two (transcription factors) to tango Transcription factor collaboration enables precise T cell state engineering tinyurl.com/tcelltfs Excited to share our preprint with @JD_Buenrostro, @cgersbach, and an incredible team of collaborators as part of @IGVFConsortium 🧵
Excited to share my postdoc work with @JD_Buenrostro now out in @Nature! "Epigenetic memory of colitis promotes tumour growth" nature.com/articles/s4158… We wanted to understand how transient inflammation can create a long-lived increase in cancer risk, even after full recovery 🧵
First test of partial epigenetic reprogramming to reverse aging for two eye conditions (glaucoma and NAION) gets FDA go ahead @lifebiosciences Based on 2020 @Nature paper pubmed.ncbi.nlm.nih.gov/33268865/ endpoints.news/exclusive-fda-…
Huge thanks to all co-authors and the inimitable @JD_Buenrostro for supporting this new direction - I got to think about evolution, engineering, chromatin biophysics, and modeling during the course of this project. For more, check out the preprint: biorxiv.org/content/10.110…
Excited to share a short article I wrote describing: Slide-tags - which enables spatial single-nucleus sequencing, allowing us to dive deeper into the complexity of tissue organization. Grateful for the amazing team and support from @insitubiology and @macosko! #ToolsOfTheTrade
Slide-tags enables spatial single-nucleus sequencing go.nature.com/48x06XP #ToolsOfTheTrade by Andrew J. C. Russell @AndyRusss @broadinstitute @insitubiology @HSCRB
The latest LLLM (large language of life) foundation model, with state-of-the art chronological age estimation, prediction of outcomes, and performance across different datasets and conditions
Introducing IN SITU GENOME SEQUENCING, a new technology to resolve DNA sequence🧬 and structure🔬 A team effort with @Andrew_C_Payne, @PaulReginato, @eboyden3, @JD_Buenrostro, and Fei Chen science.sciencemag.org/content/early/… This is how it works: (1/8)
Thrilled to see our ExIGS tool featured! A true testament to the power of collaboration. Huge congrats to the team for their hard work! 🧬@ajaylabade31 @z_chiang @CarolineComenho nature.com/articles/d4158…
Grades of DNA methylation as the basis of epigenetic cell memory... must-read. biorxiv.org/content/10.110…
T cells become exhausted and fail to control tumors in cancer patients. What if we could replicate T cell exhaustion in vitro and uncover the gene regulatory network driving exhaustion, enabling immuno-oncology drug discovery? With AstraZeneca, the Buenrostro lab addresses this gap (biorxiv.org/content/10.110…):
Study Proposes Framework to Standardize Biomarkers of Aging and Accelerate Clinical Use @jpoganik Read more: buff.ly/3OMHMBo
We are recruiting postdoctoral fellows in neurobiology and development to complement our group specializing in genomic technologies, epigenetics and machine learning. projects are very well funded and we are interested in co-mentorship. Please DM if interested in hearing more!
Our latest paper is out - a new method called "TIME-Seq" to measure biological age for just a few dollars. Great work Patrick Griffin! @NatureAging Free download rdcu.be/dvDfc
@ThomasJGriffin0 @BlackHarePress Huge congrats brother! 💪
Can we reverse aging? 7 yrs ago, Ocampo et al. showed that partial reprogramming can ameliorate aging hallmarks. But, OSKM induction has safety limitations & no new factors have emerged since. Here, biorxiv.org/content/10.110… we used 🧬 screens to find new rejuvenation factors🧵1/8
Delving into our newly released result, a thread:
Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma: A year-long functional tracking of in vivo partial reprogramming demonstrates safety and efficacy. Work from @margaretekarg @YuanchengLu @davidasinclair @bruce_ksander liebertpub.com/doi/10.1089/ce…
Can we shield the epigenome from age-related changes, much like how SIRT6 defends the genome? Using a CRISPRi screening approach, @XiaoTianPhD seeks to identify genes involved in maintaining epigenome stability. His new lab @sbpdiscovery is recruiting for various roles!
Xiao is one of the most productive and kindest scientists I have ever met! Amazing opportunity
I am hiring multiple Postdoctoral Associates for my new lab at Sanford Burnham Prebys. We use a multidisciplinary approach (multi-omics, machine learning, long-lived species) to push the boundaries of aging research. Please see more details and apply here: sbpdiscovery.hrmdirect.com/employment/job…
Congratulations HSCRB Associate Professor @jd_buenrostro for being been named a 2023 #MacFellow! @macfound macfound.org/fellows/class-…
David Sinclair @davidasinclair
617K Followers 1K Following Professor researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own. @joinlifespan
Morgan Levine @DrMorganLevine
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Nathan S. Cheng think... @realNathanCheng
16K Followers 746 Following Moonshot to end aging. Vitalist & co-founder @ Longevity Biotech Fellowship / https://t.co/XIKhk2FDDd, https://t.co/ZGc47xuFt9, @healthspancap
José Luis Ricón Fer... @ArtirKel
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Martin Borch Jensen @MartinBJensen
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Bérénice A. Benayou... @BBParis1984
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Matt Yousefzadeh @MattYousefzadeh
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Y. Ryan Lu @Y_Ryan_Lu
6K Followers 1K Following Yuancheng Ryan Lu | Understanding the molecular logics of aging and its reversal | K99-LSRF-AFAR fellow in @JswLab @MIT | Prev PhD @Harvard with @DavidaSinclair
Jae-Hyun Yang @JaeHyun_Yang
664 Followers 470 Following Postdoc | Sinclair lab | @HarvardMed | Chromatin | Epigenetics | Aging
Elliot Hershberg @ElliotHershberg
19K Followers 961 Following Partner @AmplifyPartners, writing https://t.co/LSbi0EEiHU
Lamming Lab @LammingLab
6K Followers 3K Following All views solely of Dr. Lamming and do not necessarily reflect views of my employers, funders, or societies. Retweet≠Endorsement. @[email protected]
Ruxandra Teslo 🧬 @RuxandraTeslo
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Daniel Promislow @DPromislow
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Yuri Deigin @ydeigin
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David J Glass MD @davidjglassMD
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Adam Gries @adamgries
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Matt Buckley @MatttBuckley
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UKHVAT NEWS @UkhvatNews
8 Followers 365 Following AI-media. News from the front lines of the fight for immortality.
Kyle Farh MD PhD - Il... @KyleFarh
399 Followers 1K Following Head of Illumina AI Lab. Deep Learning. Human Genetics. Perturb-seq.
rap. k. @raphaki11
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Sean Logan @SeanALL86
91 Followers 467 Following
HeavenNOW @HeavenNow26
22 Followers 479 Following 80s baby, always learning. 🌟 #truthseeker #healthfreedom
Richard Kollen @nuclearball
3K Followers 5K Following Johns Hopkins Univ., NASA, ESA, DFVLR, & SKYNET. Here for MEDICAL. I RT Doc jobs. I block some non-scientific followers as I’m not here for social.
Paul Knoepfler @pknoepfler
20K Followers 5K Following Prof @UCDAVIS peds cancer & stem cells. Blog https://t.co/oXW4PiaYAl Bsky https://t.co/xx09HxJXgF STAT https://t.co/6RAkEo8zVn Longevity skeptic
Longaevi @LongaeviBio
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✌(◕‿-)Daͥngͣe... @IDidMake
102 Followers 2K Following
369 @KMH841725459031
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Nancy J @nuri263020
13 Followers 1K Following Just a wild girl who feels deep and dreams moonlight threads 🌸
Rachel Savage @Rachel_E_Savage
239 Followers 195 Following PhD candidate in Buenrostro Lab @JD_Buenrostro @HSCRB @harvard || chromatin biology, gene regulation, single cell genomics
MR CODY LAWS @codyallenlaws01
1 Followers 113 Following
Temtsenee @temtsenee
2 Followers 290 Following
Curiosi @TeamCuriosi
23 Followers 2K Following 🏃♀️ Interested in BioE, AI, Nanobot & Quantum Mechanics for extending healthspan Stay foolish. 🧘♀️ ANATMAN - WUWEI
Dr. Dave Podorefsky @davidpodorefsky
396 Followers 3K Following Scientist | R&D | Drug Discovery | Genomics | Computational Biology | Musician & Songwriter | Chemical Engineering | Hopkinton, MA → @UMassChemEng → @UCSBChE
Trinh Phan-Canh @PhanCanhTrinh
390 Followers 2K Following Scienceholic at @MaxPerutzLabs | PhD student @MedUni_Wien | MS & BS Pharmacy UMP | BS Informatics VNU | Former UMP Lecturer | @QuocHoc_Hue Alumni
Bailee Crane @dfjda26269399
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Naurorteesm @Naurorteesm08W
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Ryan Marshall, PhD @RNMarshallPhD
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Tosewez @TosewezU8ewv
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MariaDoris @12baNw74m0CtN3
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Diamonds in the Galax... @laohuyou29665
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Aly @alysoncogene
337 Followers 981 Following harvard CPB ‘25. aging and dying 📉. rare cats, humanoid robots, and virtual worlds 📈. I sleep with AirPods in. prev: Church lab, Sinclair lab
Symplectic Manifold o... @MaxDiffusionRL
817 Followers 3K Following Likes surprisal. Wealth of weak ties. Eclectic af. Likes the unbenchmarked. Puts FEP/Hessians/Fisher info into their Claude prompt
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Tirthew @Tirthew29G3Is4
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Varelse @empiricallyadqt
115 Followers 3K Following hardware, software, wetware. livewired optimist. pyrrhonian skeptic. enthymeme enthusiast. hunting for gordian knots. per aspera ad astra
Stanislovas Jankauska... @JankauskasPhd
905 Followers 3K Following Assistant Professor at CUNY Medicine. Study the role of mitochondria in CVD, diabetes and aging.
Andrew Payne @Andrew_C_Payne
2K Followers 415 Following Currently: CEO @E11BIO building technology for mapping entire mammalian brains. Previously: PhD @MIT with @eboyden3 & @insitubiology.
WPI-Bio2Q, Human Biol... @bio2qkeio
430 Followers 4K Following #Keio University Human #Biology - #Microbiome - #Quantum Research Center (#Bio2Q), World Premier International Research Center Initiative (WPI) #Longevity
Jason Buenrostro @JD_Buenrostro
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Dnetesn @DnetesnAh6Jy
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casset @casset116270
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Caroline Comenho @CarolineComenho
136 Followers 57 Following PhD candidate with @JD_Buenrostro at @HSCRB @HMS_SysBio | epigenomics tech dev
RaeMacMillan @i8vtC7B98bmh7
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Allison @Neethibwz
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Matt Kaeberlein @mkaeberlein
31K Followers 344 Following Husband, father, scientist, athlete (sort of), CEO, recovering academic. Passionate about helping people and companion animals live longer, healthier lives.
Agingdoc🩺Dr David ... @agingdoc1
51K Followers 100 Following Longevity medicine best practices | healthspan | precision medicine | bio/acc | consulting @ https://t.co/XWGLGiTnox Connect: https://t.co/wneqWlNToL
David Sinclair @davidasinclair
617K Followers 1K Following Professor researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own. @joinlifespan
Morgan Levine @DrMorganLevine
20K Followers 514 Following VP of Computation at Altos Labs | Former Professor at Yale | Thoughts and opinions are my own
Nathan S. Cheng think... @realNathanCheng
16K Followers 746 Following Moonshot to end aging. Vitalist & co-founder @ Longevity Biotech Fellowship / https://t.co/XIKhk2FDDd, https://t.co/ZGc47xuFt9, @healthspancap
João Pedro de Magalh... @jpsenescence
20K Followers 2K Following Scientist planning to live forever (so far so good!), professor decoding the genome @unibirmingham, geek, entrepreneur, speaker, writer, keen footballer.
José Luis Ricón Fer... @ArtirKel
24K Followers 1K Following Head of Theory at @RetroBio_ , enjoyer of things, blog: https://t.co/8xDYgWBhx9
Martin Borch Jensen @MartinBJensen
7K Followers 642 Following Longevity Industrialized. @GordianBio: pooled in vivo screening for therapeutic abundance. @NornGroup, @impetusgrants: 501c3 addressing bottlenecks to progress.
Brunet Lab @BrunetLab
11K Followers 4K Following Aging lab @Stanford - Epigenomics and metabolism in #aging; Brain aging and rejuvenation; Neural stem cells; C. elegans; African #killifish
Alex Zhavoronkov, PhD... @biogerontology
37K Followers 2K Following My posts are strictly personal, not reflective of positions or policies of Insilico Medicine, which disclaims any responsibility for my individual statements.
Aging Science News @AgingBiology
33K Followers 1 Following Latest news in the biology and genetics of aging, covering longevity science, rejuvenation technologies and life-extension research. Tweets by @jpsenescence
Oded Rechavi @OdedRechavi
146K Followers 1K Following Transgenerational inheritance, q.e.d: @qedscience https://t.co/tKNk6qiSlZ TED: https://t.co/rcOm9TSTf5 Huberman Lab Podcast: https://t.co/xZTNlx9nbi
Bérénice A. Benayou... @BBParis1984
4K Followers 1K Following Associate professor @USC Gero. French scientist. Aging, omics, immunity, sex-dimorphism. Views my own. She/her.
Matt Yousefzadeh @MattYousefzadeh
5K Followers 4K Following Scientist studying aging at Columbia University. @CCTI_NYC
Y. Ryan Lu @Y_Ryan_Lu
6K Followers 1K Following Yuancheng Ryan Lu | Understanding the molecular logics of aging and its reversal | K99-LSRF-AFAR fellow in @JswLab @MIT | Prev PhD @Harvard with @DavidaSinclair
Björn Schumacher @schumacherbj
19K Followers 1K Following I'm a scientist 👨⚕️, author 📕and chair for genome stability in aging and disease at the University of Cologne
lada @ladanuzhna
11K Followers 125 Following working on epigenetic medicines for diseases of aging @ https://t.co/uvAEzU9UDt
David R. Liu @davidrliu
79K Followers 68 Following Professor at Harvard and the Broad Institute. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1
Patrick Hsu @pdhsu
72K Followers 3K Following @ArcInstitute co-founder, @Stanford professor, @ThriveCapital investor | biology and ML research | 🇨🇦 prev @harvard @broadinstitute, Fast Grants
Nature Biotechnology @NatureBiotech
324K Followers 3K Following Publishing the best of biotech science and business. Find us on Bluesky, Facebook & Instagram. Part of @SpringerNature and @NaturePortfolio.
Farooqi Lab @Farooqi_Lab
3K Followers 622 Following Professor Sadaf Farooqi’s lab @Cambridge_Uni. We study the fundamental mechanisms controlling human energy homeostasis to identify treatments for obesity.
biohub @biohub
29K Followers 601 Following Combining frontier AI & frontier biology to help scientists cure or prevent disease
Trade With Congress @tradewithcong
73K Followers 81 Following Connecting the dots, so you don’t have to. $4.4B+ traded by politicians since 2014. Go to Altoneer to trade with them 🤓
Mathelirium @mathelirium
35K Followers 15K Following applied maths & stats, comp physics, & scientific visualizations. Want great visuals for your ML, Math, Physics paper or presentation? DM me for more details.
ClaudeDevs @ClaudeDevs
515K Followers 2 Following Official updates for developers building with @ClaudeAI
Perplexity @perplexity_ai
494K Followers 76 Following Curiosity changes everything. Download our free app on iOS, Mac, Windows, and Android.
Anthony Morris ツ @amorriscode
31K Followers 2K Following claude code @anthropicAI | ex @stripe → https://t.co/AjndW0qdf0
Sam Rodriques @SGRodriques
21K Followers 233 Following Director and CEO at FutureHouse and Edison Scientific. Building an AI scientist. https://t.co/aNx8D1QmfN. https://t.co/rQYoPOwV8Q
Amanda Urke @amanda_urke
107 Followers 102 Following genomics tech dev in the 🧠 @macosko's lab @BIG_Harvard_PhD @HarvardMITmdphd @bioe_stanford @StanfordArtSwim class of '19 MN born & raised
Curt Jaimungal @TOEwithCurt
59K Followers 0 Following Exploring theories of everything, consciousness, Ai, and God. Early access episodes: https://t.co/9HHWJeJbKw For business inquiries: [email protected]
Jeff Huber 🇺🇸 @jhuber
47K Followers 26K Following Co-founder @TriatomicCap ㅣFounding CEO @GRAILbioㅣearlier: @Google Ads, Apps, Maps & ⟦x⟧ㅣf*ckcancerㅣPer aspera ad astra. 💚🤍♥️
Ashlee Vance @ashleevance
201K Followers 4K Following Writing at https://t.co/m6EtO60SiY and host of the Core Memory podcast. 2X NYT best-seller. Filmmaker @HBO (Wild, Wild Space) + @Netflix (Don't Die).
Garrett G. @DeepwriterAI
16K Followers 32 Following Personal account for the guy who created the smartest AI on earth. Opinions are my own, not DeepWriter AI's. Try it now 👇
Yulong Li Lab @yulonglilab
5K Followers 868 Following Yulong Li, Prof. of Peking Univ. : PKU (BS, Beijing) - Duke Univ. (PhD, Durham) - Stanford Univ. (Postdoc, Palo Alto) - PKU (Prof. , Beijing)
Kay M Tye PhD @kaymtye
34K Followers 864 Following Mom. Neuroscientist. She/Her. BLM. https://t.co/sN3wqA9sHH https://t.co/GgqdGIyJwi
Samuel Hume @DrSamuelBHume
49K Followers 1K Following Doctor, scientist | Trying to speed up science and solve disease
Eshan Mehra @emehra30
39 Followers 188 Following researcher @Broadinstitute | physics x regen bio @Harvard | nexus fellow @NornGroup | building next gen epigenomic tools
Andrew Payne @Andrew_C_Payne
2K Followers 415 Following Currently: CEO @E11BIO building technology for mapping entire mammalian brains. Previously: PhD @MIT with @eboyden3 & @insitubiology.
Caroline Comenho @CarolineComenho
136 Followers 57 Following PhD candidate with @JD_Buenrostro at @HSCRB @HMS_SysBio | epigenomics tech dev
ADHD Jesse @adhdjesse
120K Followers 3K Following 👋 Building Wavepal (https://t.co/6kByfgwLi4) 📙 Author of Extra Focus: The Quick Start Guide to Adult ADHD (https://t.co/wBtoaKUvpz)
MovieGainz @MovieGainz
404 Followers 367 Following Love all things MOVIES 🎬 Box Office • Physical Media • Reviews • Awards Season • Hosts of Let's B-Reel Podcast 🍿 📩: [email protected]
Jami Kuo @jami_kuo
53 Followers 183 Following
Mighty Chroma: A Home... @mightychroma
2K Followers 635 Following We ❤️ Physical Media We ❤️ Movies Your go-to for the greatest reviews & latest news on #PhysicalMedia Ask us about your favorite discs! 💿🍿
Bo Wang @BoWang87
30K Followers 3K Following Prof @UofT | Building first Virtual Cell @Xaira_Thera | Chief AI Scientist @UHN | AI & Bio & Healthcare | Inventor of scGPT, MedSAM, BioReason | Opinions my own
Jamie Justice @j_n_justice
1K Followers 360 Following Science. Aging. Life. Executive Director, XPRIZE Healthspan + adjunct faculty at Wake Forest University School of Medicine. Scientist, Mom, Outdoor Enthusiast.
🖤 Buy Physical Med... @VHSDVDBLURAY4K
81K Followers 2K Following Physical Media | Movie News | Memes | Video Games | Daredevil & Kingpin liked my Tweet | Deinfluencer
andrew gao @itsandrewgao
44K Followers 3K Following @cognition @stanford; prev @sequoia @LangChain @pika_labs; Z Fellow 🇺🇸; views my own
Tristan Tay @TristanTay1
79 Followers 38 Following
Ruochi Zhang @RuochiZhang
623 Followers 488 Following Machine Learning Scientists, Biology of Adversity Project @broadinstitute Eric and Wendy Schmidt Center postdoctoral fellow (22-25) / PhD'22 @CMUCompBio
Russ Cook @hardestgeezer
322K Followers 208 Following The first person ever to run the full length of Africa🌍 @huel
Institute on Aging @PennAging
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Anthropic @AnthropicAI
1.4M Followers 2 Following We're an AI safety and research company that builds reliable, interpretable, and steerable AI systems. Talk to our AI assistant @claudeai on https://t.co/FhDI3KQh0n.
Pat Flynn @PatFlynn
172K Followers 15K Following My new book, Lean Learning: How to Achieve More by Learning Less, comes out on June 3rd! Father, husband, entrepreneur, Pokémon YouTuber @DeepPocketMnstr 🤙🏼
Visa is doing marketi... @visakanv
171K Followers 234 Following Focus on what you want to see more of. 💪🏾❤️🔥 buy my ebooks ▲ FRIENDLY AMBITIOUS NERD ▲ (https://t.co/ilqQnEHTOz) and ꩜ INTROSPECT ꩜ (https://t.co/K7oSiNofSa)
Ramit Sethi @ramit
301K Followers 871 Following Author, host of @netflix "How to Get Rich" & the Money For Couples podcast
Freenome @freenome
4K Followers 273 Following Freenome is a high-growth biotech company developing next-generation blood tests to detect cancer in its earliest, most treatable stages.
Marie Bardi-Salinas @mariebardi
13K Followers 1K Following movieperson, you may have heard me on a podcast
Alejandro Ocampo @aocampox
684 Followers 174 Following Scientist on a mission to make dogs live longer and healthier lives. Assistant Professor at @unil Co-Founder and CEO at @epiterna_
Alex Plesa @amplesa
312 Followers 275 Following Scientist at @harvardmed and @WyssInstitute in @geochurch's lab | Working on solving aging
Jeff Bezos @JeffBezos
8.4M Followers 594 Following Six thousand years ago, someone invented the plow, and we all got wealthier. A gentle reminder that all civilizational wealth is driven by invention.
Robin Carhart-Harris @RCarhartHarris
67K Followers 3K Following Ralph Metzner Distinguished Professor of Neurology & Psychiatry, UCSF. Psychedelic neuroscientist and psychologist. https://t.co/CmvjG0IanQ
Dr. Scott Carlin @scottcarlinpt
51K Followers 456 Following Physical Therapist. Girl Dad. Runner. Sharing everything I know about running and rehab. Weekly newsletter: https://t.co/yIy1MaAmpa
Fermat's Library @fermatslibrary
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