FriendsOfSinclairLab @sinclairfriends
The amazing group of people who support our research aimed at reversing aging in order to treat diseases and dramatically extend healthy lifespan friendsofsinclairlab.com Boston, MA Joined September 2025-
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Great to be back! m.youtube.com/watch?v=rXLCug…
Scientists stopped muscle aging in mice. Blocking Hmgb1 in middle-aged mice with antibodies had remarkable results: senescent markers dropped, muscle regeneration improved, physical performance increased, and inflammation decreased.
Congrats @lifebiosciences team. Big thanks to our investors. Well done Jerry McLaughlin, Michael Ringel, Amit Shashank, Sharon Rozenzweig-L, Ivan Kaplan, @Serenapoon & team. Go ER-100🤞 Not sure we qualify as “startup” after 8 yrs & being in the clinic 😉 endpoints.news/david-sinclair…
Age reversal is natural
Best article in years
A major new paper reframes aging as a systems failure of epigenetic information. Not wear and tear but a software problem. This is what the Information Theory of Aging predicts and, if correct, means aging is reversible. Let's dive in... 🧵
Can’t wait for you to see the new episodes of Lifespan. Sign up & receive early access & bonus material. Launch April 2026 Lifespan.com ✌️
Can’t wait for the first robot to present their findings at lab meeting
We built this demo in collaboration with a clinical pathology lab. It shows a single system doing real lab tasks: tool use, precision manipulation, and high level planning. This was done in one take with no teleop and uses our skills based AI to enable generality while staying
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Today’s guest on the Free Radicals podcast is @M_S_Ringel, COO @lifebiosciences and former Managing Director at @BCG. Michael is a leader in longevity and pharma who spent 25+ years advising top pharma companies on their R&D strategy. He is now COO at Life Biosciences where he
Oh wow — so cool to see two of my favorite examples that I’ve been using in my talks for close to a decade (rockfish lifespans spectrum from 10 to 200 years and the black garden ant queen’s 30-year lifespan vs. the worker’s 1-year [rather than a month — I think Michael misspoke]) getting wider airtime as evidence that aging is a programmed adaptation. The more people making this case, the better! Here’s a video with relevant excerpts:
Today’s guest on the Free Radicals podcast is @M_S_Ringel, COO @lifebiosciences and former Managing Director at @BCG. Michael is a leader in longevity and pharma who spent 25+ years advising top pharma companies on their R&D strategy. He is now COO at Life Biosciences where he
@adityasinghnx @davidasinclair Great advice. With too much writing on a slide, the brain isn’t focused on what you’re saying either
Every week, I tell one of my students to increase the font size on their slides, especially numbers. Here’s how you know you’re good: Take 5 steps back from your laptop or monitor. If you can still read every letter & number clearly, you’re probably good 👍
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For 25 years, my team has been told we were wrong, by scientists, big pharma, the media, ethicists, and trolls. It hasn’t been easy Looking back, it was 100% worth it Here’s why you should believe in yourself… 🧵
Be discerning about companies whose mailing address is the someone's home and the office is in a mall
BREAKTHROUGH 100% Life Extension Achieved in Mouse Study @ImmortaBio youtu.be/oetFLK5z7uc
According to ITOA, NAD declines with age, causing epigenetic changes & disease susceptibility In 2010, we showed NAD-dependent enzyme, SIRT3, protects the heart 🐁 New study says NAD precursor NMN protects the heart via SIRT3 in mice fed a Western diet Why's that important? 🧵
The paper: sciencedirect.com/science/articl…
In 2006, we reported the longevity & metabolic benefits of resveratrol in mice Now, after 40 human trials with 2,551 patients, resveratrol is reported to significantly lower insulin resistance, lipids, BP & inflammation Discovery. Translation. Progress. nature.com/articles/natur…
Exercise prevents brain ageing and memory loss by strengthening the blood–brain barrier go.nature.com/4baobXk
It FINALLY happened!!!! The Rapamycin & Exercise clinical trial manuscript has been accepted 5 years in the making Special thanks to @mkaeberlein, @LifespanNews, @vitadao, everyone who donated, and viewers of my channel.
Longevity’s strongest correlate is having a dependable partner. We are creatures whose optimal biology requires tight social bonds, presumably because our ancestors’ survival once depended on them. For optimal health, rebel against today’s antisocial society 💪
Very few factors significantly slow epigenetic aging. Strong social connection is one of them. The data keep pointing the same way: healthy relationships are a key to a long and healthy life.
Ted Bowersox @USCTED
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Brett Hersh @brett_hersh
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Str @Str217554525484
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Holocaust Art Recover... @ArtRecoveryInit
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Paul Lester @LesterPaul7954
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Natalia @Natalia1475717
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Lance Larson @dlancelarson
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Mike Stewart @thatmikefellow
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M E @eBrain
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SHIHO @QuaranteShiho
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DH @danhuahao
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Rob @Bobisms11
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Logan Niqirix @LNiqirix730
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Greg Lukianoff @glukianoff
81K Followers 1K Following CEO @thefireorg. #freespeech lawyer. Buy my new book, War On Words! Newsletter: https://t.co/kOQpTdvWWy
nabogordo @minionyole
8 Followers 94 Following Explorador del cosmos interior en busca de los suspiros del unicornio cósmico. 🌌🦄✨
Andrea @AndreaA2209
18 Followers 28 Following
Limited @tryagainlimited
530 Followers 3K Following crushing it | father | husband | gamer | health-nut | theorist | philosopher | writer
Space Colonize @Spacecolonize
2K Followers 3K Following Outer Space Colonization is dedicated to the goal of colonizing outer space
Walt Rivenbark @waltrivenbark
682 Followers 6K Following Son, Husband, Father, Sales, Marketing and Technologist to the core, Apple Fan, Kite surfing when there is wind.
Vignesh Nadar @VigneshNadar2
105 Followers 4K Following Software Engineer. Love reading Books, Anime. Hobby Artist/Designer. Curious about AI & Psychology. Internet Lurker ;)
rap. k. @raphaki11
273 Followers 6K Following
Donghyun Lee @donghyunlee00
470 Followers 2K Following CS & Bio @SeoulNatlUni | Research intern @gladyshev_lab
Discomrobulated @RumpusRob
150 Followers 2K Following Experiential & product designer. Music is my marinade. Fiction reader / story lover. Southern not stupid
PermaHedge 🇨🇦�... @PermaHedge
297 Followers 3K Following #SPX Not Financial Advice. #LL3ByTheOrder #shylobots 🗝️ 👁️ 🍑
Nutrition Science @NutrioSci
73K Followers 5K Following Everything about Nutrition Science. #Nutrition #Science #Technology #Research #News #Education #Health #Life #Foods
Sean Logan @SeanALL86
91 Followers 457 Following
Nathan Paturzo @NathanPaturzo
29 Followers 118 Following
Armois @mnajlmsr
246 Followers 694 Following Ideas have wings...... Averroes للأفكار جنحان ..... ابن رشد
The Net Alchemist @AlchemistNet
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Morten Duesund @DrMortenDuesund
71 Followers 263 Following Strategic Advisor & Fixer | Cross-Border Problem Solver | Investor | Professor | Europe • UK • Eurasia
Jay "letterj" Payne @letterjbp
1K Followers 586 Following Lifetime Learner. Love all things Space; especially SpaceX.
Brock @BrockMcKean
3K Followers 6K Following e/acc | accelerating coordination asymptotically toward alignment
Dork @Eyeballs100
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Andre Watson 🧬 @nanogenomic
9K Followers 8K Following CEO @Ligandal 🧬: Tissue-specific targeting with AI + peptides (LigandForge). On a mission to enable precision personalized predictive medicine. Forbes 30U30.
Centro de Mediación ... @CentroToga
2 Followers 2K Following Cansado de litigios lentos y caros? TOGA: Todos Ganan Mediación: laboral, comercial, empresarial y tributaria. Soluciones rápidas, y mutuamente beneficiosas.
A @tripleJJJ2023
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Longaevi @LongaeviBio
7 Followers 148 Following mTOR, AMPK, sirtuins, NAD+ are all modulated by gut microbial metabolites.
OM @om__aj
213 Followers 5K Following
NucleicAI @NucleicAI
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Vinod Khosla @vkhosla
700K Followers 642 Following entrepreneurship zealot, grounded technology possibilist, believer in the power of ideas, passionate about sustainability & impact
The Nobel Prize @NobelPrize
1.3M Followers 492 Following The official feed of the Nobel Prize @NobelPrize #NobelPrize
Demis Hassabis @demishassabis
1.1M Followers 172 Following Nobel Laureate. Co-Founder & CEO @GoogleDeepMind - working on AGI. Solving disease @IsomorphicLabs. Trying to understand the fundamental nature of reality.
David Sinclair @davidasinclair
608K Followers 1K Following Professor researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own. @joinlifespan
nature @Nature
2.6M Followers 3K Following Research, News, and Commentary from Nature, the international science journal For daily science news, get Nature Briefing: https://t.co/wGmQlQ8a4D
NASA JPL @NASAJPL
3.7M Followers 127 Following The Jet Propulsion Laboratory advances science and discovery through NASA robotic missions exploring Earth, the solar system, and the universe.
Science Magazine @ScienceMagazine
4.7M Followers 458 Following Cutting-edge research, news, commentary, and visuals from the Science family of journals. Follow @NewsfromScience for stories from our News team.You might like
