Linda Karlsson @karlssonlinda1
Neuroscience PhD Student @biofinder_study 🇸🇪| Alzheimer’s disease research | Modeling & Machine learning | MSc in Engineering Physics @lunduniversity. Lund, Sweden Joined November 2022-
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Yesterday at #ADPD2024 I presented a machine learning project where we predict tau PET from more clinically accessible variables. Excited to share this work! And the manuscript is in preparation so stay tuned 😁@biofinder_study @MultiparkL
If you're joining 🇵🇹#ADPD2024🧠 this week, don't miss the BioFINDER posters and presentations! #Plasma #asynuclein #ALS #MachineLearning #TauPET #PrimaryCare #SVD #proteomics #sexDifferences #ptau #CSF #biomarkers #Alzheimer and many other topics! 🩸🧬♀️♂️🩺💉
❗️Publication❗️ Head-to-head comparison between a highly accurate plasma biomarker and FDA-approved and clinically used CSF biomarkers 🩸#ptau217 is clinically comparable or superior to CSF biomarkers to detect #Alzheimer's pathologies @NatureMedicine nature.com/articles/s4159…
I am presenting a machine learning project at #HAI2024 where we predict tau PET load and spatial information from more clinically accessible features. Come chat at poster 84! @biofinder_study
Our two @biofinder_study group winners of the data blitz presentations during the @MultiparkL retreat! 🥳 @karlssonlinda1 @SEMastenbroek
The young researcher Jacob Vogel at Lund University receives the H.M. Queen Silvia's Prize for a young Alzheimer's researcher in a ceremony at the German Church, Stockholm. @Alzheimerfonden #Alzheimer #Alzheimersdisease
Check out this cool work using mathematical modelling to describe tau accumulation dynamics
Big congratulations to the very kind and amazing researcher Anne!!! Extremely proud to have been one of her students during my time at LTH.
Big congratulations to the very kind and amazing researcher Anne!!! Extremely proud to have been one of her students during my time at LTH.
Interested in improving sensitivity and specificity of CSF biomarkers? Come talk reference proteins with me today at #AAIC, poster 279
Fantastic work and paper on a novel, more specific marker of tau pathology. 👏
Fantastic work and paper on a novel, more specific marker of tau pathology. 👏
Lecanemab is the first biological therapy that has received a traditional approval by FDA. I am very impressed by the commitment and hard work of Lars Lannfelt and his colleagues who developed this immunotherapy over the last two decades! fda.gov/news-events/pr…
Dear Twitter friends. Please help @vermeiren_marie and me with completing this survey on the use of #tau #PET in clinic and trials. The results will be used in my #AAIC plenary and eventually published. Please also SHARE and/or RETWEET! alzheimercentrum.nl/the-future-rol…
Excited to share this new manuscript! Many thanks to all participants and co-authors @OskarHansson9, @NiklasMattson4, @_JakeVogel_, @astromkalle, @SebastianPalmqv, @EStomrud and all not on Twitter.
Excited to share this new manuscript! Many thanks to all participants and co-authors @OskarHansson9, @NiklasMattson4, @_JakeVogel_, @astromkalle, @SebastianPalmqv, @EStomrud and all not on Twitter.
Mobina Fathi, MD-MPH @Mobina__Fathi
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40 Followers 10 FollowingNature Methods @naturemethods
141K Followers 1K Following Nature Methods publishes cutting-edge methods, tools, analyses, resources, reviews, news and commentary, supporting life sciences research. Tweets by editors.Yesterday was such a fun and beautiful day, racing through the Dutch countryside and raising money for Alzheimer’s research together with @_michael_scholl and his beautiful car! Many thanks to the #AlzheimerRally2024 organization team for this great day! 🚗🚗
‼️My PhD work pre-print‼️ @SonenbergLab #mTOR #TREM2 #mitochondria ➡️#Microglia need to be fit 💪 to stop AD pathology. We delved into some previously unexplored pathways microglia employ to keep up (and not get so mad). 1/ a bit overdue🧵 biorxiv.org/content/10.110…
I had a great time in Barcelona at the conference on Down Syndrome and Autosomal Dominant AD sponsored by the @DownSyndromePIA but coming home to these two was the highlight .
Very honored to receive this award😊
🎉Time to celebrate 🎉 This year's Future Faculty's Minerva leadership award winner is @lemwisse! Don't forget to register to the event! 👉 futurefaculty.blogg.lu.se/2024/04/04/fut…
Extremely happy of being awarded with the BrightFocus fellowship (@_BrightFocus ) to continue my work on #Alzheimer's disease!🎉🎊 Thanks to all the @biofinder_study team for the continuous support🙏 And specially @OskarHansson9 and @RikOssenkoppele for your mentoring
Ines is a great researcher and her work continuous to fascinate me! I am really looking forward to see her work published.
Great assembly at MultiPark lunch seminar, where young scientists present their research 👨🏼🔬 Today we heard @ines_hristovska describe proteomic changes in CSF in cerebral small vessel disease using @biofinder_study cohort.
Great assembly at MultiPark lunch seminar, where young scientists present their research 👨🏼🔬 Today we heard @ines_hristovska describe proteomic changes in CSF in cerebral small vessel disease using @biofinder_study cohort.
Spotorno et al. show that cortical mean diffusivity, a measure of cortical microstructure derived from diffusion MRI, can track disease progression on the AD continuum and could thus be a promising outcome measure in trials. tinyurl.com/mp4ewhzn; tinyurl.com/y7mramrh
Huge thanks to all that made this study possible🙏 @KantaHorie, @alexa_pichetb, @BrianGordon81, @BenzingerNeuro1, @SebastianPalmqv, @EStomrud, @SuzanneESchind1, @RandallBateman3 and especially @_JakeVogel_, @RikOssenkoppele and @OskarHansson9 And the whole @biofinder_study 🤩
We foresee that such model could be very useful for diagnosis🩺, prognosis 🔜 and patient management 📄 in the clinical setting 🏥, but also for recruiting the optimal participants into clinical trials 💊.
We view the present model as a first step toward providing meaningful disease progression staging using a single CSF measurement. We do not see it as a fixed system, but as the founding stone of using fluid biomarkers for staging AD. We hope we can see a translation into🩸 soon
Extremely happy to see this one out at last!!!🎉🎊 Here, we showed that a single CSF draw 💉is sufficient to accurately stage participants along the #Alzheimer's continuum. This has been a long and tough journey, but totally worth it to finally share it with the whole community☺️
New publication in @NatureAging led by @gesalbla ‼️ Here, we propose and validate a staging system for #Alzheimer's disease based on fluid biomarkers nature.com/articles/s4358… A 🧵 ...
New publication in @NatureAging led by @gesalbla ‼️ Here, we propose and validate a staging system for #Alzheimer's disease based on fluid biomarkers nature.com/articles/s4358… A 🧵 ...
🚨 NEW paper led by @gesalbla in @NatureAging proposes a new CSF-only staging model to characterize #Alzheimer's disease progression. PDF: nature.com/articles/s4358… w/@_JakeVogel_ @alexa_pichetb @BrianGordon81 @SuzanneESchind1 @OskarHansson9 @biofinder_study & @WashUNeurology
New publication in @NatureAging led by @gesalbla ‼️ Here, we propose and validate a staging system for #Alzheimer's disease based on fluid biomarkers nature.com/articles/s4358… A 🧵 ...
‼️ Finally you can read the beautiful CSF staging system using the latest tau biomarkers in AD by @gesalbla 🤩
New publication in @NatureAging led by @gesalbla ‼️ Here, we propose and validate a staging system for #Alzheimer's disease based on fluid biomarkers nature.com/articles/s4358… A 🧵 ...
In our paper @NatureComms, we evaluated whether AD 🩸 biomarkers could aid in selecting memory clinic patients who’d more likely prognostically benefit from undergoing tau-PET, with p-tau217 performing best @OskarHansson9 @pedrorosaneto @biofinder_study nature.com/articles/s4146…
I'm sure it will be a great presentation!💪
@SuzanneESchind1 takes the stage at #CTAD24 with her keynote presentation “Fluid biomarkers in research, clinical trials, and clinical practice” Learn more: ctad-alzheimer.com/keynotes
Plaques are very heterogenous and hard to understand only with antibodies. Can you use label free High resolution X-ray tomography for real plaque classification? Talk to Valeriia Skoryk, Oxana Klementieva to learn more! #adpd2024 poster 169 #alzheimer #amyloid #HRXT