Colleen Griffith @Griffith17431
BS, MS Chemical Engineering | interested in anything STEM & Medical, esp. ID, Cardiology | work experience in Pharmaceuticals and BioTech | she/her Baltimore, MD Joined October 2020-
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Regardless, there are data that clearly demonstrate that lowering ApoB can not only reduce the rate of progression, but reverse plaque as demonstrated in this beautiful study from last year. I’d love to have his thoughts (or Simon’s or Bill’s) as well ja.ma/3J3Q56e
This is actually false. Dave is wrong and is either being intentionally decietful or just doesn't know enough. Cancer isn't caused by low LDL-C. People who are dying of cancer happen to have low LDL-C. Reverse causality.
Today on the Daily: a special and, we think, important episode. What would a second Trump presidency really would look like? And what kind of threat would it represent to American democracy? A deep-dive into what we know from three of the best reporters in the country:…
A pro-inflammatory dietary pattern [higher intakes of low-energy beverages (diet sodas)] was associated with an increased risk of hip fracture among postmenopausal women in the Nurses’ Health Study. J Dahl et al. Arch Osteoporosis 24 Apr 2024 tinyurl.com/35584d9s
If you have an elevated LDL-C or APOB AND a Calcium Score of 0 Cholesterol lowering medications are unlikely to reduce your risk of a heart attack over the next 5 years. But you need to think about the next 50... not the next 5. That.... is a different risk equation.
propublica.org/article/cigna-… ProPublica has done it again. These terrifying glimpses inside health insurance corporations are so important. People need to understand what we're up against. These corporations don't care about you. @Cigna
What age to start (& stop) mammograms, how often to get them, & whether additional screening, e.g., breast MRI, is warranted are still decisions we should tailor to the patient, but I think all in 🇺🇸 now agree females at avg risk for #breastcancer should start mammo at 40. #bcsm
ABSOLUTE (#LDL-C) REDUCTION AS A BETTER APPROACH THAN STARTING STATINS BASED ON INITIAL BASELINE LDL FOR PRIMARY PREVENTION 👍 jacc.org/doi/full/10.10… #ASCVD #lipids #LLT #statins #CardioTwitter #medtwitter
New ASHRAE 62.1-2022 #ventilation addendum adds density correction (PDF: ashrae.org/file%20library…) Most locations will increase. Calgary #YYC at 1045 m will need 15% more outdoor air than before. BUT the new AB building code (May 1 2024) references the 2016 version!
How thrilling to see this online after 8 years in the works!!! We showed that #Lyme bacteria mimic our own“don’t eat me” signal with their P66 protein to hide in plain sight!!! This tricks our SIRPa protein to trigger the breaks on immune clearance! biorxiv.org/content/10.110…
🔥High time to wake up! SarsCoV2 is trying to stay in some patients, sorry to say….I warned you! SarsCoV2 causes T-cell damage, can persists and now more science that its also able to further infect your bone marrow……. and you still think its only the Flu😠 ➡️Megakaryocyte…
Will 50% of people die if #H5N1 jumps? Very unlikely. Yes, this is @WHO's stat BUT three important points... 1. H5N1 deaths are among a small pool of known cases. Past antibody studies of H5 suggest we are missing many infections. science.org/doi/10.1126/sc…
Emerging studies suggest that neurodegenerative disorders (Parkinson's and Alzheimer's diseases), which are characterized by profound learning and memory impairments, seem to be mediated, at least in part, by a dysfunctional gut-brain vagal axis. 1/
🚨 Clinical Dermatologists are waking up to the reality that perhaps our understanding of sunlight has been warped and that it is actually beneficial. (Thanks to @MaxGulhaneMD) for posting this! A MUST READ 👇 Sunlight: Time for a Rethink? jidonline.org/article/S0022-…
Very good analysis on the current H5N1 situation from @dr_kkjetelina in Scientific American @sciam
This research on colon cancer biomarkers "serves as a pivotal wake-up call for current microbiome research, offering solutions to propel the field forward." nature.com/articles/s4159… nature.com/articles/s4159… @NatureMedicine @ancientOmics @jeroenraes @zhu_ruixin
Do you really want to understand the Lipid Hypothesis? The following magnificent, incredibly enjoyable 5-part totally inclusive series written by David Steinberg in the Journal Of Lipid Research (open access) has long been forgotten. It was so important on my lipiddology…
Reviews on saturated fat are often of shockingly low quality but this recent one is pretty good. Covers FAQs, replacement nutrients, mechanisms, areas of uncertainty and individual variability. cambridge.org/core/journals/…
It's been just over 1 month since @USDA reported finding #H5N1 #birdflu in dairy cows. There are still many questions about what's going on & the risk it poses to people. But some things are starting to come into focus. By @MeganMolteni & me. statnews.com/2024/04/30/h5n…
Very concerning again. I don’t think stockpile of oseltamivir/tamiflu is going to get us far in an H5N1 influenza outbreak in people. It’s highly susceptible to virus resistance w/ a single mutation & it’s modestly effective if given within first 1-2 days of infection. Without…
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Regardless, there are data that clearly demonstrate that lowering ApoB can not only reduce the rate of progression, but reverse plaque as demonstrated in this beautiful study from last year. I’d love to have his thoughts (or Simon’s or Bill’s) as well ja.ma/3J3Q56e
This is actually false. Dave is wrong and is either being intentionally decietful or just doesn't know enough. Cancer isn't caused by low LDL-C. People who are dying of cancer happen to have low LDL-C. Reverse causality.
Today on the Daily: a special and, we think, important episode. What would a second Trump presidency really would look like? And what kind of threat would it represent to American democracy? A deep-dive into what we know from three of the best reporters in the country:…
A pro-inflammatory dietary pattern [higher intakes of low-energy beverages (diet sodas)] was associated with an increased risk of hip fracture among postmenopausal women in the Nurses’ Health Study. J Dahl et al. Arch Osteoporosis 24 Apr 2024 tinyurl.com/35584d9s
If you have an elevated LDL-C or APOB AND a Calcium Score of 0 Cholesterol lowering medications are unlikely to reduce your risk of a heart attack over the next 5 years. But you need to think about the next 50... not the next 5. That.... is a different risk equation.
propublica.org/article/cigna-… ProPublica has done it again. These terrifying glimpses inside health insurance corporations are so important. People need to understand what we're up against. These corporations don't care about you. @Cigna
What age to start (& stop) mammograms, how often to get them, & whether additional screening, e.g., breast MRI, is warranted are still decisions we should tailor to the patient, but I think all in 🇺🇸 now agree females at avg risk for #breastcancer should start mammo at 40. #bcsm
🧵 Just published: USPSTF recommends all women undergo routine #breastcancer screening every other year beginning at age 40, an update from the 2016 recommendation to start at age 50. ja.ma/3WmvqEO
ABSOLUTE (#LDL-C) REDUCTION AS A BETTER APPROACH THAN STARTING STATINS BASED ON INITIAL BASELINE LDL FOR PRIMARY PREVENTION 👍 jacc.org/doi/full/10.10… #ASCVD #lipids #LLT #statins #CardioTwitter #medtwitter
New ASHRAE 62.1-2022 #ventilation addendum adds density correction (PDF: ashrae.org/file%20library…) Most locations will increase. Calgary #YYC at 1045 m will need 15% more outdoor air than before. BUT the new AB building code (May 1 2024) references the 2016 version!
How thrilling to see this online after 8 years in the works!!! We showed that #Lyme bacteria mimic our own“don’t eat me” signal with their P66 protein to hide in plain sight!!! This tricks our SIRPa protein to trigger the breaks on immune clearance! biorxiv.org/content/10.110…
🔥High time to wake up! SarsCoV2 is trying to stay in some patients, sorry to say….I warned you! SarsCoV2 causes T-cell damage, can persists and now more science that its also able to further infect your bone marrow……. and you still think its only the Flu😠 ➡️Megakaryocyte…
Will 50% of people die if #H5N1 jumps? Very unlikely. Yes, this is @WHO's stat BUT three important points... 1. H5N1 deaths are among a small pool of known cases. Past antibody studies of H5 suggest we are missing many infections. science.org/doi/10.1126/sc…
Emerging studies suggest that neurodegenerative disorders (Parkinson's and Alzheimer's diseases), which are characterized by profound learning and memory impairments, seem to be mediated, at least in part, by a dysfunctional gut-brain vagal axis. 1/
🚨 Clinical Dermatologists are waking up to the reality that perhaps our understanding of sunlight has been warped and that it is actually beneficial. (Thanks to @MaxGulhaneMD) for posting this! A MUST READ 👇 Sunlight: Time for a Rethink? jidonline.org/article/S0022-…
Very good analysis on the current H5N1 situation from @dr_kkjetelina in Scientific American @sciam
Have questions about H5N1? We all do. Attempted to explain what we know and don’t know and some challenges in this Q&A for @sciam with the brilliant Megan Bartels. Read here: scientificamerican.com/article/u-s-ne…
This research on colon cancer biomarkers "serves as a pivotal wake-up call for current microbiome research, offering solutions to propel the field forward." nature.com/articles/s4159… nature.com/articles/s4159… @NatureMedicine @ancientOmics @jeroenraes @zhu_ruixin
Do you really want to understand the Lipid Hypothesis? The following magnificent, incredibly enjoyable 5-part totally inclusive series written by David Steinberg in the Journal Of Lipid Research (open access) has long been forgotten. It was so important on my lipiddology…
Reviews on saturated fat are often of shockingly low quality but this recent one is pretty good. Covers FAQs, replacement nutrients, mechanisms, areas of uncertainty and individual variability. cambridge.org/core/journals/…
It's been just over 1 month since @USDA reported finding #H5N1 #birdflu in dairy cows. There are still many questions about what's going on & the risk it poses to people. But some things are starting to come into focus. By @MeganMolteni & me. statnews.com/2024/04/30/h5n…