Sidi Chen @sidichen
Gene editing. Technology. Cancer. Immunology. Cell and gene therapy. Antibody. mRNA vaccine. @ Yale Genetics & Systems Biology. ## CRISPR in vivo ## sidichenlab.org New Haven, CT Joined December 2010-
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Excited to share our new Nature paper on in vivo CAR-NK CRISPRa screen + discovery of a hyperbooster for solid tumor nature.com/articles/s4158… Tx to Luojia, Paul, Drs Peng, Gunel, Moliterno, J Chen. #NK cell therapy @YaleGenetics @YaleWestCampus @YaleMed @YaleCancer @YNeurosurgery
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Proud to share our new work at Nature biomedical engineering on mRNA vaccine platform innovation! nature.com/articles/s4155… @Carolina Lucas @zane_zhenhao Fang @Yale @YaleGenetics @YaleWestCampus
Proud to present our work at #KCRS25 on CAR-T screens, cell therapy and kidney cancer from @YaleMed @YaleGenetics @YaleWestCampus @YaleCancer Honored to be in session with Drs. Chuck Drake at JnJ, Nadal Rios at Hutch & Patrick Ott at Farber, hosted by David Braun &Hans Hammers.
Sidi Chen retweeted
#KCRS25 Session 6 highlighted how researchers are pushing the boundaries of what immunotherapy can do for kidney cancer patients. Engaging Native Immunity with ENPP3 with Chuck Drake TCR-Engineered Cell Therapy with @RosaNadalrios Next Generation T-Cell Engineering with @sidichen Future of Cancer Vaccines with Patrick Ott #AcceleratingCures
Sidi Chen retweeted
🎉 CRI is proud to announce the 2025 CLIP and Technology Impact Award projects, a new class of high‑potential studies and tools designed to push cancer immunotherapy further and faster! Explore: bit.ly/4lzfuZi #Immunotherapy #CancerResearch #CancerResearcher
Organizing an AI symposium on 6/20 with SAPA-CT at Yale. Please check it out and all are welcome to register/attend! @YaleWestCampus
Excited to present our new work on multiplex immune gene therapies for cancer @asgct 2025 @NOLA @YaleMed @YaleCancer @YaleGenetics @YaleWestCampus
Sidi Chen retweeted
.@sidichen co-chairs a symposium highlighting the transformative field of adoptive cell therapies for #cancer treatment #AACR25 with Dr. Daniel Powell @PennMedicine @AACR @SmilowCancer @YaleWestCampus @YaleGenetics
Our lab generated 4 new lines of Cas12a transgenic mice and demonstrated utility in immune engineering, tumor modeling, and genetic disease treatment. Around to share w the field & community! @YaleMed @YaleWest @YaleGenetics @YaleData Also @LabWinslow nature.com/articles/s4155…
Our new “MUCIG” therapy @FF Zhang @ScienceChow @GW @YaleCancer @YaleGenetics @YaleWestCampus Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy | Nature Biotechnology nature.com/articles/s4158…
Our team’s new work “MUCIG” cancer therapy - Multi-target approach counters tumor growth in several cancers | Yale News @Feifei Zhang @ScienceChow @Guangchuan Wang @Yale @YaleCancer @YaleGenetics @YaleWestCampus news.yale.edu/2025/01/16/mul…
@jmuiuc @CarnegieMellon @SCSatCMU Great congrats! Exciting area and time!
Honored to serve on the panel of #AI for drug discovery in biomedicine at #AIME 2024 Utah. Very stimulating discussions on future of medicine, challenges etc, with experts and audience. @YaleData @YaleDatascience @YaleGenetics @YaleCancer @Yale_Ventures
Our first in vivo primary NK screen that discovered new NK cellular checkpoints. Kudos for team for their 5 years of work. nature.com/articles/s4158… @YaleGenetics @YaleMed @YaleWestCampus @YaleCancer @YaleData
Sidi Chen retweeted
“Building a community and paying attention to that community is the essence of getting things done.” Today #JameelClinic Advisory Board Chair and Nobel laureate Phil Sharp celebrated the 50th anniversary of his lab, “The Sharpies” — half a century of sharp minds!
Our new high fidelity enhanced AsCas12a/Cpf1 transgenic mice after five years of work. Generated by Matt Dong and colleagues here in lab at @YaleGenetics @YaleCancer @YaleMed @YaleWestCampus Anyone who want to try them out feel free to please contact us. biorxiv.org/content/10.110…
Got the cover for this one as well at Nature Biomedical Engineering :)
Our new piece of tools for gene delivery and cell therapy.nature.com/articles/s4155… westcampus.yale.edu/news/yale-scie… @YaleGenetics @YaleMed @YaleWestCampus @YaleData @YaleCancer
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