Vijay Sankaran @bloodgenes
Pediatric Hematologist/Oncologist, Geneticist, Stem Cell Biologist - @DFBC_PedCare, @BostonChildrens, @DanaFarber & @broadinstitute bloodgenes.org Boston, MA Joined August 2015-
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Thank you, @NoahKahan, for visiting our patients!!!
Thank you, @NoahKahan, for visiting our patients!!!
Congratulations, @jmartinrufino, on an incredible @BBS_Harvard Ph.D. defense yesterday!!! 🙏 @garber_manuel, @david_scadden, @BradEBernstein, and #BenEbert for being amazing examiners! So excited for all that is to come!
Wonderful to spend time with this amazing group and many others discussing how transcriptional regulation impacts blood disorders! @BertieGottgens, @emerybresnick, @VikramParalkar, @ShaiIzraeli, @DelwelRuud, @leonard_zon, and many more!
Exciting to see what our discoveries have led to so far!! Lights a 🔥 under us, as well as many other physicians and scientists!
Exciting to see what our discoveries have led to so far!! Lights a 🔥 under us, as well as many other physicians and scientists!
Published today, our reasons for optimism that success rates in drug discovery can be improved by picking the right targets using human genetics: nature.com/articles/s4158… I break the key findings down panel by panel in this thread: x.com/cureffi/status…
Published today, our reasons for optimism that success rates in drug discovery can be improved by picking the right targets using human genetics: nature.com/articles/s4158… I break the key findings down panel by panel in this thread: x.com/cureffi/status… https://t.co/k6g7paLMdA
Our new ms “Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain” is now at @Nature . rdcu.be/dEmgT! We report on human forebrain dynamic assembly during development…1/n
The future of heme-onc is very very bright!!! Congratulations!!! 👏👏👏
Grateful to meet this amazing group, including 2023 @LaskerFDN Award Winner and fellow @HarvardMITmdphd alumni David Huang, at the @the_asci meeting who helped contribute to advances that saved my retina! 🙏🙏🙏
Incredibly proud of @RichardVoit who is a recipient of a 2024 @the_asci Emerging-Generation Award!!! Congratulations, Richard!!
As Mackay and Anholt emphasise, epistasis is typically not observed in analyses of common variant effects in humans *for methodological reasons*, not because it doesn't exist
As Mackay and Anholt emphasise, epistasis is typically not observed in analyses of common variant effects in humans *for methodological reasons*, not because it doesn't exist
Excited to share with you our manuscript describing the endogenous protein La as a mediator of prime editing and the development of our PE7 editor, which can improve prime editing. For more, please check out nature.com/articles/s4158…
@SalliePermar and I just published this today in @statnews. #pediatricians are the foundation of our health care system and have an impact over the life course of our nation's health care. We make a difference!! @amspdc @ab_peds @APPDconnect @AAPDelMonte statnews.com/2024/04/02/too…
Wow!!
The haematology community recently lost an exceptional researcher, mentor, role model and friend. I was honoured to prepare this tribute with @scienceadvocacy for @ISEHSociety Exp Hematol. 🙏 to those who contributed, ♥️ to the Eaves family exphem.org/article/S0301-…
I am excited to share our preprint: “A torpor-like state in mice (TLS) slows blood epigenetic aging and prolongs healthspan”. Congratulations to @LornaLJayne and big thanks to our collaborators @prof_horvath, @bloodgenes, @VadimGladyshev and others. biorxiv.org/content/10.110…
Can anti-aging antibodies revive the immune system? In @NatureNV we previewed the latest breakthrough from Irv Weissman's team in @Nature that used immunotherapy to deplete aging stem cells. @KasuYasar nature.com/articles/d4158…
Why do Latino children have the highest risk for childhood leukemia in the US? We identify one cause for this in a paper out in @CellGenomics today, led by @adamdesmith, @LWahlster, @SoYoungJeon_Eli, @fulong_yu, @CharlestonCWKC, & colleagues: cell.com/cell-genomics/…
📢 Happy to announce our new review on stem cell #aging! We integrate traditional concepts/hallmarks of aging with emerging data on somatic evolution and stem cell competition. @NatureAging nature.com/articles/s4358…
Why can RNA only be linear or circular? It can be branched! We made multi-tailed mRNA, and we had fun! Here is our story led by brilliant graduate student @HongyuChenChem: rdcu.be/dB7ck and his cartoon illustration👇@ChemistryMIT @broadinstitute
Why can RNA only be linear or circular? It can be branched! We made multi-tailed mRNA, and we had fun! Here is our story led by brilliant graduate student @HongyuChenChem: rdcu.be/dB7ck and his cartoon illustration👇@ChemistryMIT @broadinstitute https://t.co/HYJH0FvAjU
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NEWS: We are excited to welcome our newest Principal Investigator, Kamena Kostova, PhD (@kkostova1). She will join the Institute fall 2024. The Kostova Lab seeks to uncover how complex conditions such as #cancer & #neurodegeneration first begin. More: bit.ly/4bcHc8A
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It was a pleasure to be part of this #teamwork on how HSC respond to skin inflammation and its consequences in the immune system
Preprint📢 #Inflammation causes the body to remembers to fight better next time. Here we found that skin inflammation doesn't boost immune memory like we thought—it can also dampen it! Find out how this surprising result could change our grasp of #Immunity biorxiv.org/cgi/content/sh…
🚨🔊Interested in structural variants? Genome sequencing? Pediatric cancers? Germline variants+cancer risk? Rare variants+rare diseases? If so (or even if not!), I'm delighted to share the first paper from my postdoc @VanAllenLab @DanaFarber: biorxiv.org/content/10.110… 1/12
@bloodgenes @MolecularCell @bradleybio @Doulatov_lab @SBenbarche @jpineda223 @GalvisBaquero Thank you Vijay @bloodgenes and congrats on the constant amazing papers from your lab
Excited to announce our paper out today in @MolecularCell discovering a novel splicing factor GPATCH8 and its requirement for pathologic splicing activity of mutant SF3B1. With @bradleybio & @Doulatov_lab. Led by @SBenbarche, @jpineda223, & @GalvisBaquero: cell.com/molecular-cell…
A huge congratulations to @isabellecarlota and the team for our newest paper accepted for publication in Science Advances. More to come...
@bloodgenes @jmartinrufino @BBS_Harvard @garber_manuel @david_scadden @BradEBernstein congrats Jorge!
Celebrating our 5-year wedding anniversary!
@bloodgenes @BertieGottgens @emerybresnick @ShaiIzraeli @DelwelRuud @leonard_zon @StJudeResearch @DanaFarber Wonderful to see you, Vijay, and hear about your latest work - really exciting!
The PI-student connection/tethering/iPhone charging is strong btwn these two 🤪 @TheElfLab @nsarellano9
My heart bursts. SOOOOO proud of you @nsarellano9 ❤️❤️❤️ #ESHMPN2024
My very close friend @schierlab Alex waited three years after being elected to the NAS in 2020, saying he would get inducted to the national Academy of science when I do. Here I am with him and Moses Chao. Three amigos who started back in the Skirball Institute @nyulangone ♥️
Congratulations Alexander Schier of @biozentrum, newly inducted #NASmember! #NAS161 #biology
Lovely dinner with great company to cap a 12 hour day of stimulating talks and posters at #ESHMPN2024! #mpnsm @TheElfLab @RaajitRampal @MPNlab @bose_prithviraj #JohnMascarenhas @ESHaematology
Online today in @NatureGenet is a multi-ancestry #GWAS of renal cell carcinoma #RCC that identifies 50 novel loci, subtype specific loci for clear cell and papillary subtypes, and an African ancestry-specific association at VHL. nature.com/articles/s4158… @NCIEpiTraining #NCI_ITEB
@bloodgenes @BertieGottgens @emerybresnick @VikramParalkar @ShaiIzraeli @DelwelRuud @leonard_zon @StJudeResearch @DanaFarber I spy my first Hematology inpatient attending when I was a CHOP fellow in 2005.....