Naomi Jacobs @naomicodes
Software Engineer at @benchling building tools for scientists. All opinions my own naomiajacobs.me San Francisco, CA Joined October 2016-
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@djbaskin This is basically chili oil matzo brei with crispier matzo! Amazing suggestion
My group made a game in a weekend for #ludumdare - check it out! It's a crafting/exploration game and I think it's super cute (I did all the art). One reviewer said "i was planning on only testing the game but I got sucked in for 30 min", go try it! ldjam.com/events/ludum-d…
I know exactly enough vim to get through rebasing safely and not one hotkey more
California building 5 feet of high speed rail
i’m a strong believer in the power of “granny hobbies” to improve your mental health (and detox from digital everything) reading, knitting, gardening, crafting, cooking, baking, board games, sewing, birdwatching, playing cards, drinking tea …
This is actually a pretty good summary of the excellent Orwell essay “Politics and the English Language” orwellfoundation.com/the-orwell-fou…
english has a cool built-in heuristic for detecting bullshit are most of the nouns and verbs being used latin/greek or germanic in origin? if germanic, the things being discussed are probably real physical actions and things: tree, walk, cow, shit, fall, wood, buy, leg, go
Hell yes! Mayor London Breed partnered with 7-Eleven on a new initiative to bring Japanese onigiri to convenience stores in San Francisco. I’m beyond thrilled! Got in line early yesterday and snagged one 🍙 Thank you #7eleven
From lab to approval in 11 years 🧬 And the thing is, medical applications of CRISPR are just getting started... Just yesterday, the @doudna_lab released two juicy preprints on improved delivery methodologies for CRISPR editing machinery: 1. Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP [1] 2. Engineering self-deliverable ribonucleoproteins for genome editing in the brain [2] In the first paper, they took a thermostable variant of the Cas9 enzyme from a thermophilic bacteria (Geobacillus stearothermophilus), and used directed evolution to engineer >100x greater editing efficiency. This thermostable Cas9 could be more efficiently encapsulated in LNPs, meaning that the actual protein could be delivered in a scalable vector instead of mRNA encoding the protein. This has potential benefits for avoiding immune activation and having potentially higher editing efficiency—the translation efficiency of the mRNA can be a bottleneck. They demonstrated in vivo lung and liver targeting (@justsaysinmice). The second preprint was also very cool. What if CRISPR could just deliver itself (almost like an antibody or other biologic) instead of being packaged in the first place? To achieve this, they screened for self-delivering Cas9 proteins that were fused to cell-penetrating peptides (CPPs) that could help escort them into cells. They showed some POC data for in vivo delivery into the brain via injection into mice. It's absolutely insane to see the pace of progress for CRISPR therapeutics. From basic research result to a new approved modality in 11 years. Just a day before the approval, a pair of brand new delivery strategies released from a single lab. Genomic medicine is only just getting started... What a time to be a biologist! [1] doi.org/10.1101/2023.1… [2] doi.org/10.1101/2023.1…
english has a cool built-in heuristic for detecting bullshit are most of the nouns and verbs being used latin/greek or germanic in origin? if germanic, the things being discussed are probably real physical actions and things: tree, walk, cow, shit, fall, wood, buy, leg, go
ESTIMATION GUIDE - get a dev to estimate - increase the number and time unit by one 10 minutes -> 11 hours 3 hours -> 4 days 1 week -> 2 months
@numberphile your newest video inspired me to finally update and publish better colors for my colorblind-friendly SET cards. 😊 Thanks for the great gift about one of my favorite games on my birthday! github.com/naomiajacobs/C…
Sprints
📢 Hallo women engineers! Want to learn what it's like to work in biotech? Come hang out at @benchling's HQ on March 29th to hear me and my awesome coworkers talk on a panel. No bio experience needed! events.benchling.com/engineering-fo…
Never underestimate the power of copy The copywriter behind Slack’s update jargon deserves a monumental raise
A reality that most devs working at large companies take time to appreciate: Personal connections tend to make things easier: the larger the company, the more so. The larger the company, the more noise every team has to cut through. These connections help cut through the noise.
@benchling Oops, sorry folks! I got too excited about the event and shared too early. Turns out we have a sign up limit and I wasn't supposed to share with the whole internet 😅- I'll repost if we can open it up more broadly.
Oh, right, useful details: this will be at @benchling 's HQ in SF on March 29th
Thanks @FastCompany for naming us on the Most Innovative Companies of 2023! We’re honored to be #3 in North America, alongside biotech winners @RecursionPharma & @metagenomi, who are pioneering breakthrough innovations for a better world. fastcompany.com/90848912/most-… #FCMostInnovative
New blog post! I looked at 20 years of data on pharmaceutical blockbusters and what it tells us about the past, present, and potential future of the industry atelfo.github.io/2023/02/26/pha…
i've been skeptical on the AI stuff but this is a pretty strong showing 🪱💕
My friends and I made a video game in a weekend! It's fun and quick (< 3 minutes) and it works in your browser; go play it! It's DUNE themed! ldjam.com/events/ludum-d…
Gergely Orosz @GergelyOrosz
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Taylor Poindexter @engineering_bae
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Benchling @benchling
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Dr. Samantha Hancox-L... @perdricof
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"Online Rent-a-Sage" ... @BretDevereaux
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Numberphile @numberphile
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Why you should have a... @ShouldHaveCat
4.6M Followers 244 Following The perfect account to show to your parents when you want a cat 😺❤ @FoundationOfWen
Work Chronicles @_workchronicles
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Genes in Space @genesinspace
2K Followers 4 Following Your DNA Experiment in Space! Follow us on BlueSky: https://t.co/rpNpxrcHOu
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Overwatch Research, a... @overwatchapp
419 Followers 1K Following Overwatch is now a part of Benchling. Follow @benchling for updates.
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12K Followers 1K Following Engineering manager working in tech. Tweets about tech, politics, business, and the occasional shitpost.
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847 Followers 2K Following Genetic and digital programs, Spirit, psychedelic medicine, a more just and regenerative civilization. 🐇
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155 Followers 789 Following working on a stealth mode startup, lab scientist @stanford, proteins and databases
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582 Followers 545 Following Fermentation/Automation/Data Engineer. Occasional radio maker. Froyo enthusiast. Let's get froyo together!
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465K Followers 2K Following I build things and make videos about it. Business inquiries: [email protected]
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4K Followers 1 Following Chatty alt of @danluu. Mainly on https://t.co/V3Q53o3vC3 and https://t.co/00xlxH8ipr.
Women Posting W's @womenpostingws
856K Followers 84 Following celebrating wins, wholesome, funny, and girly things :) waking up every day is a win, be proud of yourself 🫶
Bill Gurley @bgurley
758K Followers 2K Following Founder/President @p3institute Author: Runnin' Down a Dream, pre-order link below! Founder: Runnin' Down a Dream Foundation VC @benchmark Trustee @sfiscience
Memes to Show Your Ca... @ShowYourCat
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Jared T Nelson @JaredTNelson
28K Followers 3K Following Data/Compliance lawyer in Mainland China. CEO of Pathway Compliance, an ALSP based in Shanghai. Views my own and not legal advice.
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51 Followers 202 Following
War in Translation @WarTranslation
8K Followers 0 Following Voices from the war in Ukraine, in (unofficial) translation // DM or [email protected] // account managed by @noahsneider // more info+volunteering 👇
Edward Nirenberg 🇺... @ENirenberg
33K Followers 6K Following Views my own, but you can borrow them if you feel so inclined. Anti-disease. Big Nerd Energy. “A homework person.” Fun at parties. Antibody hoarder. he/him
michelle 👻 @hazelcough
3K Followers 243 Following soft-bread engineer @stripe 🍞; public transit enthusiast 🚃
Cristian Strat @cgst
5K Followers 2K Following @OpenAI MTS • Previously https://t.co/ggLxtMqdgz, @Coinbase, @MemoAIHQ (acq by @Coinbase), @Twitter, @Summify (acq by @Twitter), @Infoarena • 🇺🇸🇷🇴🇨🇦🇨🇭
Nicholas Schiefer @nschiefer
494 Followers 241 Following Trying to turn confusion into something better. PhD student @MIT_CSAIL. 🇨🇦 in 🇺🇸. Previously: @Apple, @Caltech, @vaxthestates
✨ Jean Yang ✨ @jeanqasaur
23K Followers 4K Following Dev tools all day all night. Founded @akitasoftware, acquired by @getpostman. Former programming languages professor @CSDatCMU.
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ACS Synthetic Bio @ACSSynBio
11K Followers 315 Following This account is no longer active or monitored. For updates about ACS Synthetic Biology, follow @ACSBioMed and @ACSPublications.You might like
