Gene Regulation @generegulation
Gene regulation news, events and opinions. #chromatin #nucleosome #TFbinding #CTCF #cancer #epigenetics #openscience. Also @[email protected] generegulation.org London, UK Joined January 2013-
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If you like gene regulation and want to join a stimulating international environment - with cutting edge facilities - top healthcare and family benefits. Join us for a post-doc @embl - funded by ERC embl.org/jobs/position/…
PhD position open on lcRNA and phase separation in the lab of our collaborators Isabel Chillón and Robert Feil @IGMM_Montpel in sunny Montpellier. Great project, great lab, great place. Go there! More info here: adum.fr/as/ed/voirprop…. Or get in touch with Isabel directly!
You have perturbed TFs (for example disease vs healthy) and genome-wide H3K27ac data, what TF activity tools would infer the perturbed TFs that are more likely to be validated? According to our results, the top 3 tools: RcisTarget, MEIRLOP and monaLisa biorxiv.org/content/10.110…
Thanks for the highlight Grant! All the credit to @DrJaneXu @columbiacancer @CSCIColumbia — but the best is yet to come!
Thanks for the highlight Grant! All the credit to @DrJaneXu @columbiacancer @CSCIColumbia — but the best is yet to come!
Great collaboration with @DrZoeWaller and Dr Ke Li in Exeter! Hope it will benefit the community 😊 iM-Seeker: a webserver for DNA i-motifs prediction and scoring via automated machine learning academic.oup.com/nar/article/do…
A great opportunity available for bioinformatics scientists to explore epigenetics in our lab. @MCRCnews @FBMH_UoM @MCF_UoM @MCRBreastCentre jobs.manchester.ac.uk/Job/JobDetail?…
Join us for your #PhD or #MDPhD if you are interested in exploring how networks of transcription factors & chromatin modifiers can time development by generating transcriptional oscillations. Apply here 👇
Excited to finally share my work with @charlesdanko on the regulatory syntax governing transcription initiation and training genomic DL models on diverse genomes. doi.org/10.1101/2024.0…. Blurb thread below: 0/8
Glad that our sequence model of promoters in human genome is now published in @ScienceMagazine. Check out the paper for a deep dive into the sequence basis of transcription initiation at the basepair level: science.org/doi/10.1126/sc…
Seeking someone looking for a two-year postbac position to get my group up and running at Yale University! We will be utilizing chromatin tracing and other multiplexed imaging approaches to study the relationship between 3D genome organization and epigenetic memory in embryos!
(1/n) excited to share that our study on how condensate-promoting ENL mutations drive tumorigenesis is out at @CD_AACR! aacrjournals.org/cancerdiscover…
"caQTLs and haQTLs capture regulatory variations not associated with eQTLs and explain ∼49% of the functionally annotated GWAS loci" Been clear for a while that accessibility & histone marks provide more info for explaining & fine mapping GWAS loci than expression. 1/
"caQTLs and haQTLs capture regulatory variations not associated with eQTLs and explain ∼49% of the functionally annotated GWAS loci" Been clear for a while that accessibility & histone marks provide more info for explaining & fine mapping GWAS loci than expression. 1/
Great opportunities with exciting projects in my lab!
Great opportunities with exciting projects in my lab!
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) nature.com/articles/s4158…. Thread ⬇️⬇️⬇️ (1/8)
🚨Transcription and Chromatin UK is back for 2024🚨 We will be in Newcastle from 25th to 27 Sept. Register your interest so you're the first to know when registration opens 🧬 biochemistry.org/events-and-tra…
We are looking for a PhD candidate to work on the "histone code hypothesis" using epigenetic rewriting techniques. Deadline 12th of May. adum.fr/as/ed/voirprop… @rkoszul @pablonavarroLAB @G__Fischer @maxvcg @djost_physbiol @GAlmouzni @alphatauri2011 @leonidmirny
Preprint alert! 🎉I am excited to share the work from our enjoyable collaboration with @wendy_bickmore @josh_brickman labs. Investigating the role of PRC2 in stabilising the developmental transcriptional response during endodermal differentiation. doi.org/10.1101/2024.0…
Do you like #ChIPseq & #CUTnRUN as much as we do? Join the #PALSSummerSchool2024 and learn 🎨The Art of Peak Calling ⛰️ (#biochemistry and #bioinformatics) by @AnnaNordin96 the #CUTnRUN Master from @liu_universitet @WCMM_at_LiU REGISTER > trippus.net/summerschool
Do you like #ChIPseq & #CUTnRUN as much as we do? Join the #PALSSummerSchool2024 and learn 🎨The Art of Peak Calling ⛰️ (#biochemistry and #bioinformatics) by @AnnaNordin96 the #CUTnRUN Master from @liu_universitet @WCMM_at_LiU REGISTER > trippus.net/summerschool
📣 we’re excited to see all the fantastic abstracts coming in, if you haven’t submitted yet then you have until midnight BST tomorrow!👨💻🧑💻👩💻 There are prizes to be won 🤓 Register for the symposium: register.oxfordabstracts.com/event/51330?pr… Submit your abstract: auth.oxfordabstracts.com/?redirect=/sta…
Come join us in Oxford as an Associate Professor in Molecular and Cellular Biochemistry. We are considering a wide range of research areas, but I would note that we have a vibrant chromatin and gene regulation community. Happy to answer questions if you are interested. Please RT!
Karolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.Anshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundajeArjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12Maxim Greenberg @maxvcg
6K Followers 1K Following Group leader @IJMonod. When I say "epigenetics" what I really mean is "DNA methylation".Schübeler Lab @SchubelerLab
4K Followers 430 Following Studying gene regulation in chromatin @FMIscienceLuca Giorgetti @LucaGiorgetti
4K Followers 336 Following Chromosome conformation, Transcriptional regulation, Physical modeling. https://t.co/FOLO4qJoz8Patrick Cramer @mpgpresident
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18K Followers 5K Following I'm not on twitter anymore, find my on Bluesky or MastodonAkis Papantonis @AkisPapantonis
3K Followers 1K Following Professor for Translational Epigenetics, University Medical Centre Goettingen, University of Goettingen, DE …oftentimes aspiring fiction writer.Cedric🧬➰🧬Fesc.. @CedricFeschotte
8K Followers 2K Following Prof @Cornell, #firstgen, immigrant 🇫🇷🇺🇸, he/him. Come for the memes, stay for the transposon and virus stuff.Nucleosome papers �.. @Nucleosome_Bot
5K Followers 9 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]Jian Ma @jmuiuc
7K Followers 1K Following Ray and Stephanie Lane Professor of Computational Biology at CMU School of Computer Science @CMUCompBio @SCSatCMU @CarnegieMellonMark Dawson @MAF_Dawson
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4K Followers 2K Following Assistant Professor, Biochemistry Department, Transcription & Chromatin biology, Outdoor enthusiast, Dog lover (otters too), Occasional politics 🇵🇭🇺🇲🇨🇦Benoit Bruneau @benoitbruneau
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230 Followers 217 Following Group leader at @CRBM_Montpel. I'm interested in how spatial organization of transcription inside the nucleus controls embryo development.[email protected]... @Roubo3elzain
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275 Followers 838 Following Grad student in the Sabari lab at UT Southwestern Medical Center. Interested in gene regulation, condensates, and neurobiology. 🇲🇽Joseph Patria @JNPatria
20 Followers 70 Following Doctoral Candidate | Parcells Lab | UD | I study molecular virology and the virus-host interactions of the MDV oncoprotein during infectionGautham Ganesh @gsgautham98
20 Followers 217 FollowingTimothy Ciesielski @TimCies
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4K Followers 940 Following Associate Professor, NCDE, LSHTM, United Kingdom. Associate Professor, MRC/UVRI and LSHTM Uganda. Genomics | GWAS | Africa | Capacity Building | Global HealthKaustubh Wagh @WaghKaustubh
108 Followers 210 Following Postdoctoral Fellow @NCIResearchCtr, @NIH. Tracker of single molecules.Karthik Viswanathan @Karthik140801
133 Followers 540 Following Incoming PhD student @harvardmed. BS @iiscbangalore, 2x Scholar @ragoninstitute ,@harvardmed. Love immuno & epigenetics.Chaima BESSAADI @CBessaadi
1 Followers 35 FollowingKarolin Luger @LugerLab
9K Followers 1K Following (she/her). Chromatin and cryoEM afficionada. Still a fan of crystallography. @Nucleosomepolice on bsky. Here today, blue tomorrow. Opinions are my own.Anshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundajeArjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12Maxim Greenberg @maxvcg
6K Followers 1K Following Group leader @IJMonod. When I say "epigenetics" what I really mean is "DNA methylation".Schübeler Lab @SchubelerLab
4K Followers 430 Following Studying gene regulation in chromatin @FMIscienceWendy Bickmore @wendy_bickmore
6K Followers 86 Following Director of MRC Human Genetics Unit @mrc_hgu @EdinUniv_IGC - but tweeting in my own capacity. Supporter of fundamental science. Airedale terrier owner.Luca Giorgetti @LucaGiorgetti
4K Followers 336 Following Chromosome conformation, Transcriptional regulation, Physical modeling. https://t.co/FOLO4qJoz8Patrick Cramer @mpgpresident
13K Followers 601 Following President, Max Planck Society @maxplanckpressAnders Sejr Hansen @Anders_S_Hansen
4K Followers 2K Following Associate Professor @MITdeptofBE : https://t.co/uy48t7k949 Interested in understanding the relationship between 3D genome structure and functionBen Sabari @bsabari
2K Followers 991 Following Assistant Professor at UTSW studying nuclear organization by transcriptional condensatesMichael Love @mikelove
18K Followers 5K Following I'm not on twitter anymore, find my on Bluesky or MastodonAkis Papantonis @AkisPapantonis
3K Followers 1K Following Professor for Translational Epigenetics, University Medical Centre Goettingen, University of Goettingen, DE …oftentimes aspiring fiction writer.Cedric🧬➰🧬Fesc.. @CedricFeschotte
8K Followers 2K Following Prof @Cornell, #firstgen, immigrant 🇫🇷🇺🇸, he/him. Come for the memes, stay for the transposon and virus stuff.Nucleosome papers �.. @Nucleosome_Bot
5K Followers 9 Following Publications about nucleosomes. Maintained by @TeifLab. Also see @TF_binding_bot, @CTCF_papers, @cfDNA_papers, @generegulation. @[email protected]Mitch Guttman @mitchguttman
3K Followers 190 Following Molecular biologist interested in non-coding RNAs, nuclear organization, and gene regulation. Professor at CaltechJian Ma @jmuiuc
7K Followers 1K Following Ray and Stephanie Lane Professor of Computational Biology at CMU School of Computer Science @CMUCompBio @SCSatCMU @CarnegieMellonMark Dawson @MAF_Dawson
5K Followers 1K Following Fully support🇺🇦 Haematologist & Scientist @PeterMacCC and @UMCCR Group Leader @TheDawsonLab - views expressed are my ownMiguel Branco @BrancoLab
3K Followers 960 Following Epigenetics and transposons. @brancolab.bsky.socialNature Genetics @NatureGenet
128K Followers 2K Following Nature Genetics is a monthly journal publishing high impact research in genetics and genomics. RT/like=interesting/relevant, not necessarily endorsement.Geoff Faulkner @Faulkner_Lab
3K Followers 313 Following Professor, University of Queensland. Retrotransposons and genomics. Views my own. Scholar publications: https://t.co/xQu0hWudj1 @faulknerlab.bsky.socialSusanne Bornelöv @sus_bo
156 Followers 128 Following Wellcome Career Development Award fellow @Cambridge_Uni interested in data-driven methods to understand gene regulation and genome organisationBenjamin Werner @BenjaminWerner_
1K Followers 564 Following Reader in Somatic Evolution @QMBCI. UKRI Future Leader Fellow. What is hidden is beautiful.Albert Tsai @altsaiphys
230 Followers 217 Following Group leader at @CRBM_Montpel. I'm interested in how spatial organization of transcription inside the nucleus controls embryo development.Grosshans Lab @LabGrosshans
420 Followers 171 Following Studying mechanisms of developmental clocks and timersAntonis Antoniou @antonis02
494 Followers 428 Following Cancer Genetic Epidemiologist, Professor at University of Cambridge @cambridge_uniKenOliveLab @KenOliveLab
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1K Followers 722 Following Associate Professor at @WarwickLifeSci @warwickuni. Co-founder of @Cytecom (https://t.co/D8sSfj8lmV). Biologist at interface to physics. Japanese man in England.UCL Cancer Institute @uclcancer
5K Followers 550 Following @UCL Cancer Institute: talented researchers and clinicians working to translate research discoveries into strategies to prevent, diagnose and treat cancer.Simone Zaccaria @ZaccaSimo
758 Followers 269 Following CRUK Career Development Fellow Group Leader of Computational Cancer Genomics (CCG) at the UCL CI @CRUKLungCentre and Visiting Scientist at the Francis Crickthomas wicker @thomaswicker314
256 Followers 41 Following Researcher on transposable elements and genome evolution. Happily married to the most patient wife in the world and proud father of two daughters. Hobby artist.🧬 The Coster Lab �.. @CosterLab
490 Followers 202 Following Dr. Gideon Coster's Genome Replication lab @ICR_London. Studying what happens when DNA becomes its own enemy...Itamar Harel @ItamarHarel
751 Followers 293 Following Assistant Professor, Genetics @ the Hebrew University, and a dad. Experimental biology of vertebrate aging and related diseases using the killifish modelIrina Mohorianu @imohorianu
192 Followers 198 Following Head of Bioinformatics/ Scientific ComputingDaniel Alpern @satyagrakha
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210 Followers 276 Following Twitter account of the Physics of Life Cluster of the KU LeuvenDmitry Ghilarov @dghilarov
429 Followers 365 Following Group Leader @ John Innes Centre. Structural biology/Cryo-EM🔬❄️ RiPPs biosynthesis, peptide antibiotics, topoisomerases. Views are my own. 🤍💙🤍Christian Mayer (@chr.. @chr_mayer
990 Followers 443 Following Research group leader at the MPI for Biological Intelligence, studying the regulation of neural fate decisions during development. @[email protected]König Lab @koenig_lab
1K Followers 585 Following RNA biology group @IMBMainz Run by lab members 🧬 #Splicing #RNAModifications #RBPs #iCLIP #miCLIP #RQCClaudio Mauro @ClaudioMauro6
1K Followers 811 Following ‘Whatever you can do or dream you can, begin it. Boldness has genius, power and magic in it’. Prof of Metabolism & Inflammation. Italo-Brit. Opinions my own.Emmanuelle Bignon, Ph.. @DrEmmaBignon
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123 Followers 189 Following We work on cellular senescence, which we think is linked to both cancer and agingCentre for Chromosome.. @CCB_Galway
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2K Followers 466 Following Latest news and updates from the exome and genome sequencing service at the Exeter Genomics Laboratory, Royal Devon University Healthcare NHS Foundation TrustCaroline Wright @carolinefwright
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2K Followers 40 Following Director, @MolecularOncLab & @HopkinsThoracic Biorepository Co-leader, Molecular Tumor Board @hopkinskimmel. Bringing multi-omics discoveries into IO trials.Benjamin Evans @DrBenjaminEvans
967 Followers 958 Following Lecturer in Medical Microbiology at The University of East Anglia | Antibiotic resistance, evolution and diversity. Views are my own.Glennis Logsdon @glennis_logsdon
2K Followers 348 Following Assistant Professor at @PennGenetics and @PennEpiInst | T2T, HPRC, & HGSVC member | Loves genomics, epigenomics, & synbio | https://t.co/uAAPsUcWOhSimona Giunta @Simona_Giunta
437 Followers 375 Following Associate Professor at University of Rome @SapienzaRoma Head of Laboratory of Genome Evolution @GiuntaLab studying Centromeres & Human DNA Repeats Stability🔬Segun Fatumo @SFatumo
4K Followers 940 Following Associate Professor, NCDE, LSHTM, United Kingdom. Associate Professor, MRC/UVRI and LSHTM Uganda. Genomics | GWAS | Africa | Capacity Building | Global HealthThe Genetics Society @GenSocUK
5K Followers 334 Following The Genetics Society was founded by William Bateson & Edith Rebecca Saunders in 1919 & is one of the oldest learned societies devoted to Genetics in the world.Puck Knipscheer @PKnipscheer
167 Followers 95 FollowingBrooks Lab @TheBrooksLab
834 Followers 65 Following The Brooks Lab @UCSC | Department of Biomolecular Engineering | We study #DNA and #RNA sequencing data to fight #cancerAlessandro Russo @Al3ssandroRusso
796 Followers 530 Following Medical Oncologist at A.O. Papardo, Messina (Italy)Stephen Ågbomson @Xagbomson
475 Followers 832 Following Scientist | Heterochromatin 🧬🤫~ Structural biologist @nyugrossman| Armache Lab | 🇬🇭Erika Alden DeBenedic.. @erika_alden_d
3K Followers 2K Following PI @TheCrick and founder of @Align_Bio. Former astronomer 🌎 recovering computer scientist 🤖 current synthetic biologist 🧬🧪Hasan Yardimci @YardimciLab
332 Followers 207 Following Group leader @TheCrick. Visualising DNA replication machinery one molecule at a time.William Cross @wchcross
420 Followers 443 Following Researcher in Cancer Genomics, Big Data, and Biomarker discovery. Lecturer in Bioinformatics and Cellular Pathology, University of WestminsterMichael A. Goldman @MAG46XY
414 Followers 484 Following Professor & Former Chair of Department of Biology at SF State; human genetics, evolution. gene expression, personalized medicineJennifer Frost @neverlethetruth
257 Followers 550 Following Wellcome Trust CDA funded group leader at King’s College London. Interested in placentas/endosperms, transposons and epigenetics.Raffaella Nativio @NativioR
72 Followers 52 FollowingJean Loup Faulon @jeanloupfaulon
408 Followers 299 Following Research Director @Inra_France Professor @OfficialUoMMahdi Moradi Marjaneh.. @DrMahdiMoradi
209 Followers 660 Following Advanced Research Fellow @ImperialInfect @imperialcollege | Bioinformatics scientist with clinical backgroundEric Stutheit-Zhao @zhaoEZ
570 Followers 411 Following RadOnc resident @UofTDRO and genomic data scientist. @CancerResearch postdoc at @pmcancercentre. @PMGlobalCancer/@DKFZ Int'l fellow. #MDPhD alum from @UBC.Enrique Sanz-Garcia @Esanzgarcia
353 Followers 474 Following Medical Oncologist at @pmcancercentre. Assistant Professor at @UoT. Interested in Inmunotherapy, precision medicine and ctDNA in GI and HN tumors.Emma Louise Robinson,.. @Robinson7L
1K Followers 2K Following Sr. Manager in Scientific Communications at Edwards Lifesciences. Comms Director at AMWA. Woman In Science. 👩⚕️❣️👩💻 #clinicalaffairs #scicommCaroline Watson @carolinewatson
1K Followers 782 Following Group Leader @EarlyCancerCam | Research: clonal haematopoiesis, MDS, AML & blood cancer evolution 🩸🔬🧬 | Honorary Consultant Haematologist 🩺 @CUH_NHSTigger Tigger burning.. @TiggerBurning
4K Followers 214 Following Тигры все умеют, но ничего не делают, потому что не хотят (с) Но что-то они все же делают, вопреки себе. Молекулярная и клеточная биология - моя профессия.Ivana Bozic @IBozic_
515 Followers 279 Following Associate prof. of applied math @UW. Using math to understand cancer. Branching process fan.The Plant Cell @ThePlantCell
35K Followers 1K Following Leading international society-published journal with fast turnaround time, true peer review by top plant scientists, first-class post-acceptance science editingParenthood in 19 seconds.
🌟 Be part of our team! Join our lab for a postdoc in computational biology, focused on multi-omics profiling in time and space. Apply now: embl.org/jobs/position/…
📢 Save the date for the next London Mathematical Biology Conference, happening 9-10/9/24 @TheCrick. Registration opens soon with many opportunities for contributed talks and abstracts. Spread the word!
Introducing the Domainome... Site saturation mutagenesis of 500 human protein domains reveals the contribution of protein destabilization to genetic disease by @ToniBeltran13 @CRGenomica @sangerinstitute @BGI_Genomics biorxiv.org/content/10.110…
Really interesting paper in Nature Immunology today (Broquet et al.) They found that people who recover from sepsis have a reduced cancer risk in the years that follow (vs. matched people with non-septic infections): This was recapitulated in a controlled setting in mice - mice…
Pleased to share with you that our joint effort with @CarstenSchulte4 on “Mechanotransduction in Stem Cells” was accepted for publication! I would like to thank @d_rosaba @AkisPapantonis @solana_jordi @palankarr @ChemEpi and Dario Bonanomi for their feedback!
We are living in the TikTok Intifada: ignorant impassioned Americans watch videos of Islamist disinformation on social media and repeat it, thinking they’re doing something good. In reality, they are repeating lies and assisting anti-democratic Islamist terrorism. This woman is a…
Our first foray into the fascinating field of DNA repair! Congrats to postdoc Chris Zerio @chriszerio, who tested hundreds of oligos to identify one that trapped the helicase of human Polymerase θ in the process of annealing two strands of DNA. tinyurl.com/jaddar9u
The Anti-Israel movement divides Jews into two: If you’re committed to the destruction of the Jewish State, you’re lionized as an “anti-genocide Jew” (i.e. a good Jew). But if you’re committed to the preservation of the Jewish State, you’re slandered as a “pro-genocide Jew…
Last week to register for our @irelandchrom in person symposium in Galway this May! Should be a super meeting for anyone interested in epigenomics, transcriptomics and chromatin. Registration deadline this Friday.
Save the date! Our 3rd annual symposium is coming up on May 22nd in @uniofgalway. If you are interested in chromatin, epigenetics, transcription, histones, single-cell genomics and much more please join us. Free registration through this link: allirelandchromatinconsortium.org/symposium2024
📢Science Communication Course Alert!!! 📢 Register now for a free,online, and super-exciting course, organized by @laszlorban57 and Szabolc Nagy. Learn everything you need to know about #ScienceCommunication and beyond!!! Register here:aquaculture.uni-mate.hu/en/advanced-co… #YoRC @eu_fish
Hamas-ISIS released a video of the hostages Keith Sigal and Omri Meiran, who have been held hostage since October 7th. Our people are standing united with the Meiran and Sigal families and with all of the families of the hostages. Hamas-ISIS opened this war. They committed a…
All I see is a transcription factor searching for its target binding site
Magnetic chaotic pendulum 📹Physicsfun
📢📢Dear friends, I'm thrilled to introduce LiftOn, our new homology-based annotation lift-over tool🚀 Join my talk at @RECOMBseq Saturday April 27th at 2:50PM! @JakobHeinz9 @celinehohzm @alan_mayonnaise @alaina_shumate @elapertea @StevenSalzberg1 🔗github.com/Kuanhao-Chao/L… (1/5)
@BeatrizGerFalc representing @EllisLab_ @CPDR_Labs at #embochromatinbio24 Great job!!!! @PCF_Science @NCIResearchCtr @nciccr_gmb
@RongFan8 providing the perfect final talk at #embochromatinbio24 discussing the use of #singlecell and #spatial analysis in aging and cancer #Epigenetics in Singapore @YaleCancer @nciccr_gmb @CPDR_Labs @YaleBme
Thank you @EMBO for giving me a chance to talk about our work at the Chromatin in Cancer Biology Meeting. #EMBOchromatinBio24 I had a fantastic time and met amazing people. Highly recommend. meetings.embo.org/event/24-chrom…
Happy to share our @NatureComms paper showing that prolonged TFIIH binding to nonexcised DNA damage causes severe neuronal and developmental failure. This can be prevented by depletion of XPA or TTDA, which stabilize TFIIH-DNA binding. nature.com/articles/s4146…
Reversible depletion of Polycomb proteins can induce cancer in the absence of driver mutations @Nature nature.com/articles/s4158…