Lander Lab @LanderLab

https://t.co/bRCIwbP1FJ lander-lab.com La Jolla, San Diego Joined January 2014

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Lander Lab @LanderLab

a year ago

Last chance to apply to the Cold Spring Harbor #cryoem course this March (application deadline is Jan 15th)! Learn all about sample prep, microscope operation, and image processing at this fun 2-week course @kollmanlab @Jen_Cash_11 @cshlcourses meetings.cshl.edu/courses.aspx?c…

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Lander Lab @LanderLab

2 years ago

Congrats to our grad students who pitched therapeutic targets at this year's @ScrippsGradPrgm Drug Discovery Shark Tank - particularly Shelby @ShelbyFerrier and Morgan @m_m_gee on their winning proposal to target Cholera toxin subunit B, which raised $4 million!

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Hurley Lab @TheHurleyLab

2 years ago

Proud of new work tinyurl.com/yhz4c6ry from the lab by Zhicheng (Chen) Cui @Chen3dem using single-particle cryo-EM on liposomes to show how mTORC1 integrates nutrient and growth factor signaling at lysosomes, collab. w/ @G__Napolitano, A. Esposito, and A. Ballabio.

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Lander Lab @LanderLab

2 years ago

You can now follow us at bsky.app/profile/lander…

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Lander Lab @LanderLab

2 years ago

The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex! biorxiv.org/content/10.110…

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Lander Lab @LanderLab

2 years ago

@AlanRoseman3 @jhschaef Mystery solved. And fascinating! Thanks Alan

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Lander Lab @LanderLab

2 years ago

Let us know if you recognize this complex

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Lander Lab @LanderLab

2 years ago

@mimi1inh @scrippsresearch My bench skills are long gone…

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Lander Lab @LanderLab

2 years ago

Proof our lab skills are cutting-edge—both at the microscope and the (pumpkin carving) bench! 🎃🔬 #CryoEM #PumpkinScience @scrippsresearch

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Alessandra Magistrato @Magistrato_Lab

2 years ago

Ready for the final day of the BPS meeting on 'Emerging Theoretical Approaches to Complement Single-Particle Cryo-EM' in Trieste! 🔬 We had outstanding speakers, great science, and friendly atmosphere. Thanks to @BiophysicalSoc @cecamEvents, @palermo_lab @RommieAmaro @LanderLab!

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Doug Kojetin @DougKojetin

2 years ago

Apply now and come work at @VanderbiltU with me and my outstanding colleagues in the Center for Structural Biology! Would be thrilled to recruit more #NMR friendly colleagues! 😉🙌 @VanderbiltCSB @VandyBiochem @VUBasicSciences

Vanderbilt Center for Structural Biology @VanderbiltCSB

2 years ago

The @vanderbiltfirst application for tenure-track faculty positions in Structural Biology & Imaging or Genetic and Omic Discovery & Health Disparities is open. Priority deadline to apply is Nov 4! More info: vanderbiltfirst.com/open-positions/ #postdocjobs #BlackInBiophysics

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ludo @ludovic_autin

2 years ago

Mesoscale Explorer molstar.org/me/ Paper out !! Excellent work with @asrmoin @dsgoodsell and @sehnaldavid doi.org/10.1002/pro.51…

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Lander Lab @LanderLab

2 years ago

Some thoughts on the current state of single particle cryo-EM map/model validation. (TLDR: preferred orientation remains a big problem, ❤️ Q-scores. There's been progress, but there's still more to do. ) authors.elsevier.com/sd/article/S09…

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Alessandra Magistrato @Magistrato_Lab

2 years ago

The registration deadline of the meeting "Emerging theoretical approaches to complement single-particle cryo-electron microscopy" is today! Join us in Trieste, Italy, with an outstanding list of speakers. biophysics.org/2024trieste#/ Pls RT & Apply !

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Lander Lab @LanderLab

2 years ago

@RubinsteinJohn @GonenShane @jzhaosbp Grid factory set up in La Jolla thanks to @RubinsteinJohn & @jzhaosbp! Efforts spearheaded by @lalexandrescu1, carbon or gold with a bunch of different hole sizes and spacing. Come by any time @GonenShane !

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Lander Lab @LanderLab

2 years ago

We always thought nucleotide state strictly defined AAA+ conformation, but Jeff Mindrebo's work on mito LONP1 suggests more is at play - substrate interactions also drive protein translocation! Revisiting & rethinking the hand-over-hand mechanism: tinyurl.com/49y7a6h6

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Lander Lab @LanderLab

2 years ago

@CrollTristan Finally getting around to using this, very pleased with the implementation. Thanks Tristan! Is it possible to color the residues according to Q-score like in the OG Chimera plugin?

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Jennifer Cash @Jen_Cash_11

2 years ago

Hey all new(ish) structural biology PIs out there - I started a slack workspace geared toward us! If you’d like to join, DM me your email and method(s) of choice, and I’ll add you to the group.