Erika Alden DeBenedictis @erika_alden_d
PI @TheCrick and founder of @Align_Bio. Former astronomer 🌎 recovering computer scientist 🤖 current synthetic biologist 🧬🧪 erikadebenedictis.com London, UK Joined October 2008-
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Confusingly, the panel I'm on at Synbiobeta about synthetic biology for space 🚀 *doesn't* have the word 'moonshot' in it... while the one I'm on about normal old regular Earth 🌎 synthetic biology *does*... 😂
Astera is seeking input on foundational innovations (think: organisms and hardware) that could help synthetic biology scale. We just issued a call for ideas and are awarding five $1,000 bounties to the best ones we get. More info here 👇 astera.org/call-for-ideas/
Learn how synthetic biology is shaping the future of #sustainable food systems and #healthcare in #space in this session at #SynBioBeta2024: synbiobeta.com/attend/synbiob… #spaceExploration
Listening to another great talk, this one by @erika_alden_d, and on how much it costs to build big scientific data sets. Artificial Intelligence and Automated Laboratories for Biotechnology: Leveraging Opportunities and Mitigating Risks nationalacademies.org/event/41736_04… via @theNASEM
So cool to see @Align_Bio’s work drawn up like this! 🎨🤩 Congrats to Pete on the talk 👏
So cool to see @Align_Bio’s work drawn up like this! 🎨🤩 Congrats to Pete on the talk 👏
Congrats Ally! Space is a great application area where we need shelf-stable biotech
Congrats Ally! Space is a great application area where we need shelf-stable biotech
People like structure because it’s a way to pretend like you understand how a protein works. Nobody likes looking at wiggling jiggling protein hairballs because proteins are *actually* complicated, and that makes humans sad 😭
People like structure because it’s a way to pretend like you understand how a protein works. Nobody likes looking at wiggling jiggling protein hairballs because proteins are *actually* complicated, and that makes humans sad 😭
At FutureHouse, we always try to find brilliant people before they're famous: Shannon before information theory, or Einstein before relativity. It's the biggest win when we do. If you don't know about her yet, you will soon. @MichaelaThinks signed with FutureHouse last week.
Sure scientists spend decades using AI to publish nonsense statistical results but publish one giant AI rat testicle and suddenly it's a crisis
Group leader @erika_alden_d was featured in a @Nature interview yesterday, where she discussed her experience setting up a new lab and the hope that her research could one day help with missions to Mars 🧫🚀 nature.com/articles/s4158…
Got a pesky peak at -120 ppm? Fluoride cramping your style? We’ve got a hack for you! @k_mat15 @jazzyjewel_ @erika_alden_d @biorxivpreprint @UCLLifeSciences #NMRchat #19F_NMR #NMR #RealTimeChem 🧲🧪🧵👇: (1/7) biorxiv.org/content/10.110…
New from me in FAS! 👇 How self-driving labs can end science stagnation and a research agenda for how USG can drive adoption of this emerging tech platform
New from me in FAS! 👇 How self-driving labs can end science stagnation and a research agenda for how USG can drive adoption of this emerging tech platform
Aggressively agreeing and scheming w @erika_alden_d @D_R_Goodwin @AsteraInstitute… lots of exciting irons in the fire coming soon 🔥
I think the sad actual answer to "What is the biggest open challenge in biology?" is: 1. Getting people to share data. 2. Structuring, organizing, and annotating data with metadata so it's useful. 3. Building higher-level abstractions so people can efficiently work with big data.
synthetic biology
Papers improve after peer review. Yes, probably. But I'd like to see, as a control, whether there'll be a comparable (or bigger) improvement if the editors just told the authors "work on it for additional 2 years and then resubmit".
An interesting trend I found: Among the top 10 national winners at the Intel/Westinghouse Science Fair from 1990 to 2002, 66% of them are now in academia. Among the same group from 2003 to 2014, less than a third are academics.
Niko McCarty 🧫 @NikoMcCarty
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4K Followers 3K Following The moon has a face like the clock in the hall@erika_alden_d Because it's time for a Mars-Shot!
@andrewwhite01 I have an idea i think we can get 100% on MMLU 4-shot we should discuss
Want a quick primer on the science behind why Xaira just launched with a $1B+ seed round? The wonders of peer view and publishing have very conveniently decided to just publish our review on how generative AI is transforming de novo protein design! sciencedirect.com/science/articl…
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If you’re me, first you switch universities and then careers/sectors. And while I’m both getting my ass kicked and having the time of my life, the only thing I can say for sure is I’ve learned more about myself and the world in recent years than almost any prior period
How do you address the feeling you are wasting your precious time on this planet when you could be doing something else? It’s distressing for some, I surmise?
apparently, you can create a greenhouse material that’s so resonant with thermal infrared that you should be able to warm mars by 35K with about 0.3 kg/s of continuous injection (warming about a decade or a half decade or so). carbon nanorods, they don’t have to be that good,…
If you're investing and bio and want to drive sector-wide productivity gains, these are the areas you should be thinking about. Full thoughts here: sam-rodriques.com/post/key-probl… 5/
Turns out all you ever needed was an impossibly enormous reusable rocket. Logistics rules all. 70 years of paper missions spending 98% of their ink trying to cram 20 lbs of stuff into a 10 lb bag. All their insights irrelevant once we build a 10000 lb bag. This trend applies…
The Moon is where the growing capability gap between SpaceX and NASA is about to become glaring. NASA wants to build an "Artemis base camp" but realistically can't. There's pressure from higher ups to cut and run and do humans to Mars, but they can't do that either.
Listening to another great talk, this one by @erika_alden_d, and on how much it costs to build big scientific data sets. Artificial Intelligence and Automated Laboratories for Biotechnology: Leveraging Opportunities and Mitigating Risks nationalacademies.org/event/41736_04… via @theNASEM
For anyone who has been an academic, this is such a true observation by @a_m_mastroianni
I had a blast writing this piece alongside the 50Years team! Amazing to dig into the science and connect it to the economics to see how big of a difference a synthetic microbiome therapy could make. Let's get this science happening!
What's more valuable - 💩 or SaaS? Augmenting gut microbiomes by eating the right microbes in a pill could treat 20+ diseases in a market worth $500B per year, almost 2x the size of the SaaS market. (1/8)
Can you evolve an acoustic protein? Yes, but first you have to invent a system for high throughput acoustic screening! Congrats to @robertchurt, @ZhiyangJin and colleagues on this advance in biomolecular ultrasound. #gasvesicles biorxiv.org/content/10.110…
“There is nothing magical about the way we currently communicate science. It can change.” drugmonkey.scientopia.org/2024/03/27/bil…
After months of heads-down work with my stellar team deploying our Trilobots across the U.S., I am delighted to announce that I was awarded a spot on the 2024 Forbes 30 Under 30 list alongside my Co-Founder, Maximilian Schommer, for @trilobio!
I was going to announce my latest essay with a thread, but I think Alex just saved me the job. Science can learn from startups: "Developing the Problem-Focused Founder." punkrockbio.com/p/developing-t… TLDR: We can create more small-team, high-agency opportunities for big problems.
Many people asked what was behind this cultural shift towards industry in academia. Decided to dig into the latest @NSF data on sources of R&D funding to find out. The answer is pretty shocking!
You can now get a PhD while working at a startup! Amazing work @RetroBio_ on paving a new path for aspiring scientists!
We are proud to announce the Retro PhD! Retro College is now accredited in both the EU and USA to grant PhDs. Our first 2 students have been accepted, and we have openings for 3 more. retro.bio/careers/
New capability! Predicting microbial growth conditions from amino acid composition biorxiv.org/cgi/content/sh…
Synechocystis PCC6803 round single-celled cyanobacteria that swims towards light with uncanny accuracy. It's mostly transparent, but the round shape and high refractive index of the cell lenses the light into a spot. Then it swims away from the spot. elifesciences.org/articles/12620