Dr. Matt DeVane @drdevane
Preventive Cardiologist. Author "Heart Smart". Passion for EARLY heart disease detection and treatment- What's your CAC? Three incredible daughters❤️ San Francisco- Bay Area Joined February 2009-
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hbr.org/2013/06/how-to… Starting to prep for a lecture to our PCPs about the newest in heart disease prevention. I'm trying to think outside the box here. This seems like a good place to start. Any other good resources? @johnmuirhealth @carolynlaceymd @DrEugeneYang
Another Monday morning. Time To Refocus: Heart healthy diet- nuts, olive oil, vege's and fruit. No processed food. Alcohol just two days this week. No red meat this week. 8,763 steps a day. Find some sun. I'll do my best- @American_Heart @johnmuirhealth @carolynlaceymd
Fish oil? It's all about the EPA! Treatment with icosapent ethyl (IPE) reduced risk of major adverse cardiovascular events by 25%. The active ingredient of IPE, EPA, has shown beneficial activity at several points along the continuum, all of which contribute to the overall…
Fish oil? It's all about the EPA! Treatment with icosapent ethyl (IPE) reduced risk of major adverse cardiovascular events by 25%. The active ingredient of IPE, EPA, has shown beneficial activity at several points along the continuum, all of which contribute to the overall…
THANKS NLA! Don't leave it to your doc- TAKE CHARGE YOURSELF. Know your : LDL ApoB (or non-HDL) (total cholesterol and ratios are useless) Lp(a) Blood Pressure Blood Sugar Creatinine From here--> you begin. @nationallipid @johnmuirhealth @carolynlaceymd
THANKS NLA! Don't leave it to your doc- TAKE CHARGE YOURSELF. Know your : LDL ApoB (or non-HDL) (total cholesterol and ratios are useless) Lp(a) Blood Pressure Blood Sugar Creatinine From here--> you begin. @nationallipid @johnmuirhealth @carolynlaceymd
Our bodies are sytematically designed for movement. Our brains do not like a sedentary lifestyle. Activity treats depression better than meds (not for everyone- but many). Check out the bottom of this graph- AND MOVE! @ChristophBurch @Heart_BMJ @johnmuirhealth @carolynlaceymd
Our bodies are sytematically designed for movement. Our brains do not like a sedentary lifestyle. Activity treats depression better than meds (not for everyone- but many). Check out the bottom of this graph- AND MOVE! @ChristophBurch @Heart_BMJ @johnmuirhealth @carolynlaceymd
Have a Happy, Heart-Healthy, Valentine's Day! (Thanks @ESC_Journals for the graphic)
Congrats. Nice work. Wider spread Lp(a) is needed. I'm doing a one-time screen on all my patients. Given that an Lp(a) level of 175 mg/dL confers equivalent risk of ASCVD to that of genetically diagnosed FH- broadened Lp(a) testing may be justifiable. @AlexRazavi @sciencedirect
Congrats. Nice work. Wider spread Lp(a) is needed. I'm doing a one-time screen on all my patients. Given that an Lp(a) level of 175 mg/dL confers equivalent risk of ASCVD to that of genetically diagnosed FH- broadened Lp(a) testing may be justifiable. @AlexRazavi @sciencedirect
Big Picture: Benefits of statins outweigh the risks of a bump in glucose. "The ADA standards of care for diabetes recommend that statin therapy should be initiated in individuals with diabetes and other cardiovascular risk factors." @NeilFlochMD @EricTopol @johnmuirhealth
Big Picture: Benefits of statins outweigh the risks of a bump in glucose. "The ADA standards of care for diabetes recommend that statin therapy should be initiated in individuals with diabetes and other cardiovascular risk factors." @NeilFlochMD @EricTopol @johnmuirhealth
Always respect the ESH: With BP- Age matters. The ESH guidelines target BP <140/80 mm Hg for patients 65-79 years of age. For adults ≥80 years of age, the threshold is even more lenient, targeting SBP between 140 and 150 mm Hg. @rblument1 @escardio @ESC_Journals…
Always respect the ESH: With BP- Age matters. The ESH guidelines target BP <140/80 mm Hg for patients 65-79 years of age. For adults ≥80 years of age, the threshold is even more lenient, targeting SBP between 140 and 150 mm Hg. @rblument1 @escardio @ESC_Journals…
We need help!!! "long training and certification pathways, hyper-specialization, an aging population that is living longer and with multiple comorbidities, coupled with other factors like the increasing complexity of cardiovascular care, are among the leading pressures…
We need help!!! "long training and certification pathways, hyper-specialization, an aging population that is living longer and with multiple comorbidities, coupled with other factors like the increasing complexity of cardiovascular care, are among the leading pressures…
More reasons to go plant based. Tiny changes matter. "every 3% of calories swapped for plant-based protein from animal-based options was linked to increased odds of avoiding declines in thinking skills , mental and physical health, type 2 diabetes and heart attacks."…
More reasons to go plant based. Tiny changes matter. "every 3% of calories swapped for plant-based protein from animal-based options was linked to increased odds of avoiding declines in thinking skills , mental and physical health, type 2 diabetes and heart attacks."…
Take a statin and walk --> live YEARS longer. "the combination of statin use and healthy lifestyles was significantly associated with a 30 % and 44 % lower risk of all-cause and cardiovascular mortality in participants with high CVD risk compared with participants not taking…
Take a statin and walk --> live YEARS longer. "the combination of statin use and healthy lifestyles was significantly associated with a 30 % and 44 % lower risk of all-cause and cardiovascular mortality in participants with high CVD risk compared with participants not taking…
Obesity is going to be distant memory. A matter of when...... not if. "The plethora of efficacious obesity pharmacotherapies with different mechanisms of action will allow tailored treatment plans based on individual’s preference, comorbidities and treatment response."…
Obesity is going to be distant memory. A matter of when...... not if. "The plethora of efficacious obesity pharmacotherapies with different mechanisms of action will allow tailored treatment plans based on individual’s preference, comorbidities and treatment response."…
Statins prevent cardiovascular events the best because they prevent new atherosclerotic lesions. The lesion that never happens can never cause a clinical event. Know your LDL, ApoB and Lp(a)! @johnmuirhealth @carolynlaceymd #knowyourCAC #CardioTwitter
Great syncope review in Nature. Hoping AI can help in the challenging landscape of my patients "passing out". In a systematic review, Goh et al. expressed that machine J. Clin. Med. 2024, 13, 727 17 of 23 learning algorithms hold 88.8% sensitivity, 81.5% specificity, and an…
Great syncope review in Nature. Hoping AI can help in the challenging landscape of my patients "passing out". In a systematic review, Goh et al. expressed that machine J. Clin. Med. 2024, 13, 727 17 of 23 learning algorithms hold 88.8% sensitivity, 81.5% specificity, and an…
WebMD says losing weight is simple math. If only it was that simple. @WebMD @NeilFlochMD @johnmuirhealth @carolynlaceymd
WebMD says losing weight is simple math. If only it was that simple. @WebMD @NeilFlochMD @johnmuirhealth @carolynlaceymd https://t.co/XPaXNhM0WT
Using THC/cannabis? Think it's harmless? Your cardiovascular system doesn't think so- @ESC_Journals @escardio @johnmuirhealth @carolynlaceymd
KEY POINTS: The clinical evidence in favor of apoB is now definitive! ApoB is a more accurate marker of cardiovascular risk and the adequacy of lipid-lowering therapy than LDL-C or non-high-density lipoprotein cholesterol. @JACCJournals @Drlipid @carolynlaceymd @johnmuirhealth…
KEY POINTS: The clinical evidence in favor of apoB is now definitive! ApoB is a more accurate marker of cardiovascular risk and the adequacy of lipid-lowering therapy than LDL-C or non-high-density lipoprotein cholesterol. @JACCJournals @Drlipid @carolynlaceymd @johnmuirhealth…
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Exercise combined with GLP-1 medications improves weight loss maintenance and body composition. thelancet.com/journals/eclin…
Total annual expenditure for adults with HF in the US in 2018 was $179.5 billion Time to start prioritizing and investing in prevention and treatment? jacc.org/doi/abs/10.101… @boback @HeartDocSadiya @NMHheartdoc @rblument1 @JACCJournals @DLBHATTMD
Coronary CT angiography in patients with stable chest pain? This trial showed ⬇️ CV events without ⬆️ cath lab referral. Rationale —by detecting subclinical CAD (impossible with stress testing), we can instill preventative tx before CV events occur. SCOT-HEART Trial, NEJM 2018 ♥️
This is a fantastic story on the development of inclisiran (LEQVIO). You will learn a lot. Kudos to the authors. @nationallipid @society_eas
👉Harnessing RNA Interference for Cholesterol Lowering: The Bench‐to‐Bedside Story of Inclisiran ☝️In 2021, <20 years after the discovery of PCSK9, inclisiran became the first RNA interference therapeutic approved in the United States for LDL‐C lowering in patients with…
I guess a 30% pay cut over the last 20 years is still not enough 🤬 beckersasc.com/asc-news/physi…
“Wegovy is now the first weight loss medication to also be approved to help prevent life-threatening cardiovascular events in adults with cardiovascular disease and either obesity or overweight,” John Sharretts, MD @EndocrineToday @GoHealio Read more 👇 healio.com/news/cardiolog…
I just published Why are we getting Fat? It’s the Insulin, Stupid. link.medium.com/Z9sbhqbINHb medium.com/@drjasonfung/w…
AI helps cardiologists deliver personalized healthcare—but there is still plenty of work to do cardiovascularbusiness.com/topics/artific…
FDA Grants MACE Reduction Indication for Semaglutide tctmd.com/news/fda-grant…
Here, accruing 9,000–10,500 steps/day was associated with the lowest mortality and incident cardiovascular disease risks observed in individuals with a mean age of 61.1 years.
2024 ACC Expert Consensus Decision Pathway for Treatment of Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee | Journal of the American College of Cardiology jacc.org/doi/10.1016/j.…
Today, the FDA approved #semaglutide to reduce risk of CV disease in #obesity & #overweight This is the FIRST approval for such an indication The decision is based on SELECT trial with semaglutide lowering CV events by 20% Cardiovascular outcome trials are costly but worth it
🥳@FDA Approves First Treatment to Reduce Risk of 🩷Problems Specifically in Adults with #obesity or Overweight fda.gov/news-events/pr… #cardiotwitter #obesity #medicine
Empowering personalized pharmacogenomics with generative AI solutions | Journal of the American Medical InformationCan generative AI help PGX Counseling?@BCMDeptMedicine @BCM_CVRI @BCM_HGSC @pnatarajanmd academic.oup.com/jamia/advance-…
Cardiovascular disease is NOT a man's disease ❌ #CVD 💔 is responsible for 35% of deaths in women each year – more than all cancers combined. Yet, CVD in women continues to be understudied, under-diagnosed and under-treated. Let's stop ignoring women. #IWD2024 #WomensDay
For individuals w/ combined FH and high Lp(a), cholesterol-lowering treatment seems to be protective against progression into microvascular dysfunction 🔗atherosclerosis-journal.com/article/S0021-… @society_eas #EASSoMe @karolinskainst
📰 BIG NEWS! We now carry both strengths of generic Farxiga (Dapagliflozin Propanediol) on costplusdrugs.com! 📢 ❗️ costplusdrugs.com/medications/da… Sign up here: costplusdrugs.com/create-account
🔴 Estimating potential cardiovascular health benefits of improved population level control of LDL cholesterol through a twice-yearly siRNA-based approach: atherosclerosis-journal.com/article/S0021-… #meded #cardiology #CardioEd #cardiotwitter #medtwitter #cardiox #medicine #medical
Lipidology like you’ve never seen or heard! Join @UofLMedicine’s @DineshKalra - this talk will change your practice @UofLCardiology, @UofLHealth @uoflmedschool •Cardinal Minute: youtu.be/sbzGLH-lxiA •YouTube: youtu.be/l5wIdS7YADs •VuMedi: vumedi.com/video/manageme…
Reinstating LDL-C Measurement as a Quality Metric: This Is the Way - ScienceDirect sciencedirect.com/science/articl…