Paul Tesar @TesarLab
GirlDad | Professor @CWRUSOM developing glial therapies for neuro diseases | DPhil @UniofOxford @NIHOxCam | Co-founder @convelotx | Director @riseupneo | Foodie tesarlab.com Cleveland, Ohio Joined August 2011-
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So cool to see our recent paper on environmental chemicals affecting brain health on the cover of Nature Neuroscience! Congrats again to @ErinFCohn and the team. Special thanks to Ella Maru Studio @Ella_Maru for the artwork
Our May issue is now live! nature.com/neuro/volumes/…
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Paul Tesar retweeted
Our May issue is now live! nature.com/neuro/volumes/…
Excited to share this excellent article by Teddy Amenabar @TeddyAmen in The Washingotn Post @washingtonpost. It provides a clear & balanced look at our recent discovery of a class of household chemicals that are harmful to the brain's myelinating cells. wapo.st/4dcYUL6
Proud to see work from our lab making its way to patients. I am hopeful that the investigational drug, ION356, being tested by Ionis will be found to be both safe & effective in people with Pelizaeus Merzbacher disease🙏 Link to our 2020 @Nature paper: nature.com/articles/s4158…
Our May issue is now live! nature.com/neuro/volumes/…
Paul Tesar retweeted
Chemicals Found In Popular Household Products Potentially Linked To Autism, Multiple Sclerosis, Study Suggests go.forbes.com/c/yXec
Thank you @EricTopol for highlighting our paper. An open access link to the full article is here: rdcu.be/dCpPr
New and worrisome: common household chemicals can directly harm oligodendrocytes, brain health nature.com/articles/s4159… @NatureNeuro @TesarLab @CWRUSOM Quarternary ammonium compounds (disinfectants) and organophosphate flame retardants implicated from organoids and expt'l models
Paul Tesar retweeted
MS and autism among brain health risks from common household chemicals newsweek.com/ms-autism-hous…
Open access link to the full paper: rdcu.be/dCpPr
I am also grateful to our supporters, including the @NIH_NINDS, @mssociety, @HHMINEWS, @nyscf, sTF5 Care, and the Long, Walter, Peterson, Goodman, and Geller families.
Common household chemicals pose a risk to the brain’s myelinating cells Thrilled to share groundbreaking findings from our latest study led by @ErinFCohn at @CWRUSOM's Institute for Glial Sciences, in collaboration with the U.S. @EPA. nature.com/articles/s4159…
Paul Tesar retweeted
Great work by @bllclayton, @TesarLab, & the team. Such an insightful dive into modulation of astrocyte reactivity. @ScienceLemon92 and I were honored to write the @NatureNeuro N&V on this piece - see rdcu.be/dzXrM. (1/2)
Excited to share that my first postdoc publication is officially out! Combining an astrocyte cellular platform and chemical screening we identified drugs that can suppress the formation of pathological astrocytes and promote neuroprotection. thedaily.case.edu/fixing-rogue-b…
Paul Tesar retweeted
A phenotypic screening platform for identifying chemical modulators of #astrocyte reactivity reveals histone deacetylase 3 (HDAC3) inhibitors as suppressors of pathological astrocyte reactivity @TesarLab @bllclayton nature.com/articles/s4159…
Read the full scientific paper here 👇 rdcu.be/dy7in
Together, we are redefining the future of neurological disease treatment by targeting glial cells!
🌟Drugging astrocytes to stop neurodegeneration I am thrilled to resurface on X to share a significant breakthrough from our team in the Institute for Glial Sciences @CWRUSOM, shining new light on the path to combating neurodegenerative diseases. thedaily.case.edu/fixing-rogue-b…
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Jonathan Kipnis 🟦 @jonykipnis
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Shane Liddelow 🍊 @LiddelowSA
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