Luke Roberts @NeuroLR
Clinical Development Leader; Founder Silicon Neural; Physician; Developing the future of cardio-renal medicines and gene therapy. views are my own. siliconneural.com London, England Joined August 2015-
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On way to ASGCT, presenting Friday afternoon. Looking forward to see the crew there.
The demise of patum peperium is sad but it’s been a while since I’ve had it, preferring now some good quality Cantabrian anchovies on toast thickly spread with butter. I recommend Don Bocarte #patumpeperium #donbocarte
🐟 Relish your last pot of Gentleman’s Relish – it’s officially toast telegraph.co.uk/news/2026/04/0…
#AskBio announces completion of enrollment in the Phase 2 GenePHIT trial of AB-1002 for heart failure. The trial randomized 173 participants, marking a key milestone. Initial results are expected in 1H 2027. Full Release → askbio.com/completion-of-…
Very pleased to have our phase 1 data published in Nature Medicine today.
A terrible fire has devastated the NPUK office, a vital support for families facing Niemann-Pick diseases. I just donated to help them rebuild. Please consider sharing and giving if you can. gofundme.com/f/urgent-appea…
So that’s ESC done for another year..great to connect with colleagues from around the world as always
determines the PTS against a success threshold. Outputs include the MCS, Bayesian posterior distribution and log-likelihood curve. I’ll see if I can generalise for different scenarios and add a safety PTS element too. Could be useful.
Had a great time recently exploring probability of technical success (PTS). Created a nice app that calculates HRs across different trial parameters using Monte Carlo simulation incorporating a correlation matrix to account for each paired correlation then
Off to ESC-HF in Belgrade - should be a good meeting.
Viewpoint from @james_hillis, Edward Scheffer Cliff, and @KNVokinger: The FDA's recent authorization of an AI-powered medical device for dementia prognosis marks a step in the regulation and clinical implementation of #AI in healthcare. ja.ma/412jSqQ
@supercarblondie This is true - but you have to keep your foot down and hope you get out from under it before you need to stop or slow down too much.
Great end of the week in Denver working on the gene therapy trial, filed US patent for Silicon Neural then hotfooting it back to London to hit the ground sprinting Monday
Announcing The Stargate Project The Stargate Project is a new company which intends to invest $500 billion over the next four years building new AI infrastructure for OpenAI in the United States. We will begin deploying $100 billion immediately. This infrastructure will secure American leadership in AI, create hundreds of thousands of American jobs, and generate massive economic benefit for the entire world. This project will not only support the re-industrialization of the United States but also provide a strategic capability to protect the national security of America and its allies. The initial equity funders in Stargate are SoftBank, OpenAI, Oracle, and MGX. SoftBank and OpenAI are the lead partners for Stargate, with SoftBank having financial responsibility and OpenAI having operational responsibility. Masayoshi Son will be the chairman. Arm, Microsoft, NVIDIA, Oracle, and OpenAI are the key initial technology partners. The buildout is currently underway, starting in Texas, and we are evaluating potential sites across the country for more campuses as we finalize definitive agreements. As part of Stargate, Oracle, NVIDIA, and OpenAI will closely collaborate to build and operate this computing system. This builds on a deep collaboration between OpenAI and NVIDIA going back to 2016 and a newer partnership between OpenAI and Oracle. This also builds on the existing OpenAI partnership with Microsoft. OpenAI will continue to increase its consumption of Azure as OpenAI continues its work with Microsoft with this additional compute to train leading models and deliver great products and services. All of us look forward to continuing to build and develop AI—and in particular AGI—for the benefit of all of humanity. We believe that this new step is critical on the path, and will enable creative people to figure out how to use AI to elevate humanity.
Our #clinical and #translational research hub is now live! Explore the page to learn more about our editors, including if they'll be in your area soon, and editorially curated content: hubs.li/Q02Y7NCx0
30 years ago #Today, Netscape Navigator 1.0 browser was released. It was the dominant web browser in terms of usage share in the 1990s.
It’s fascinating when something as mundane as an FBC is investigated through a different lens revealing important insights. Haematological setpoints are a stable and patient-specific deep phenotype | Nature nature.com/articles/s4158…
The capability for producing "mirror life" is out there and poses danger. When some scientists who worked on this became aware, they stopped pursuing it, and co-authored this piece, along with over 30 leading scientists—a @ScienceMagazine policy forum that lays out the risks science.org/doi/10.1126/sc…
mike @mike98572986
2K Followers 818 Following Interested in small caps, biotech and Clearpoint $clpt, $par, $als.to, $idt,$xpel,$leat, $slyg,$dcth, $frfhf, $goog $twst
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C. Michael Gibson MD @CMichaelGibson
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npj Digital Medicine @npjDigitalMed
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Nature Rev Immunol @NatRevImmunol
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Science Immunology @SciImmunology
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bioRxiv @biorxivpreprint
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HF Collaboratory @hfcollaboratory
2K Followers 1K Following The Heart Failure Collaboratory is an academic consortium of stakeholders committed to improving the eco-system of heart failure research.
Guinness World Record... @GWR
947K Followers 3K Following The global authority on record breaking achievements since 1955 🌍 Be Part Of It
NVIDIA @nvidia
2.6M Followers 48 Following The official handle for NVIDIA. Blog: https://t.co/JAn5eKOTBT Support: https://t.co/6ln5FVnA2o All our social media: https://t.co/Uc56dL57Dh
Nature Communications @NatureComms
250K Followers 480 Following Nature Communications is an open access journal publishing high-quality research in all areas of the biological, physical, chemical and Earth sciences.
John Nosta @JohnNosta
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Cell Reports @CellReports
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Cell Press @CellPressNews
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CVCT - CardioVascular... @CVCTForum
4K Followers 5K Following A Forum for #CardioVascular Clinical Trialists. Best update on the latest clinical trials of the year! 23rd CVCT Forum | December 7-9, 2026
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J.R.R. Tolkien @JRRTolkien
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Circ: Heart Failure @CircHF
8K Followers 476 Following Circulation: Heart Failure is a journal of the American Heart Association. Editor-in-Chief: Nancy Sweitzer, MD, PhD. RT/follows do not imply endorsement.
HFSA @HFSA
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British Society for H... @BSHeartFailure
11K Followers 2K Following ACCOUNT NOT IN USE Making heart failure a national priority whilst improving the delivery of equitable, high quality heart failure care.
Heart Failure Forum @HeartFailureFrm
49K Followers 3K Following #HeartFailure Forum: bringing together patient, medical, and policy communities to help improve the management of #WorseningHeartFailure. Supported by Bayer AG.
eLife - the journal @eLife
175K Followers 698 Following The funder-researcher collaboration and open-access journal for research in the life and biomedical sciences | @eLifeCommunity
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23K Followers 3K Following Placeholder for the scientist and author. Active on Substack not on X. https://t.co/CKyLzw5bHK
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UK Prime Minister @10DowningStreet
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arXiv.org @arxiv
48K Followers 184 Following News from https://t.co/enurGFxpcS, a free distribution service and an open archive for scholarly articles. For help with arXiv, see https://t.co/LcWuhM0BOl
Intuitive Machines @Int_Machines
107K Followers 414 Following The Space Infrastructure Company Next Lunar Mission: IM-3 & Lunar Data Relay Satellite
Chris Mayer @chriswmayer
58K Followers 279 Following Portfolio manager and co-founder, Woodlock House Family Capital. Author of: 100-Baggers, et al. Disclosure: https://t.co/aqMvGMUdGT
Cell & Gene Therapy @CGT_Insights
4K Followers 170 Following OA journal from BioInsights; Senior Editor: Prof. Chris Mason, AvroBio & UCL. Register to read all content free of charge.
TradingView @tradingview
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Koyfin @KoyfinCharts
74K Followers 390 Following Koyfin is a financial data and analytics platform for researching global stocks, ETFs, Mutual Funds, macro trends, and portfolios. Sign up for free.
Keith Hornberger @KRHornberger
12K Followers 260 Following TPD-med chem-hiking-cocktails / while I have a connection to Arvinas, all opinions expressed are mine and do not represent the views or positions of the company
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ASGCT @ASGCTherapy
10K Followers 2K Following Advancing knowledge, awareness, and education leading to the discovery and clinical application of genetic and cellular therapies to alleviate human disease.
Demis Hassabis @demishassabis
1.1M Followers 172 Following Nobel Laureate. Co-Founder & CEO @GoogleDeepMind - working on AGI. Solving disease @IsomorphicLabs. Trying to understand the fundamental nature of reality.
AskBio Inc. (AskBio) @ask_bio
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Genomics Education @genomicsedu
22K Followers 2K Following NHS England's Genomics Education Programme. Providing knowledge, skills and experience in #genomics #NHSgms #genomes100K #NHS #GenomicsConversation
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29K Followers 2K Following We’re working to enable faster and deeper genomic research, to bring genomic healthcare to all who need it.
PHG Foundation @PHGFoundation
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Oundle School Archive @OundleArchive
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35K Followers 3K Following DJ/Presenter/Producer: X-Posure Radio X Fri & Sat 11pm-2am / X-Posure Daily Global Player Mon-Thu / Tape Notes https://t.co/ZRXRYX06UnYou might like
