Circ: Heart Failure @CircHF
Circulation: Heart Failure is a journal of the American Heart Association. Editor-in-Chief: Nancy Sweitzer, MD, PhD. RT/follows do not imply endorsement. ahajournals.org/journal/cirche… Joined February 2017-
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Epicardium-derived fibroblasts drive the fibro-inflammatory response in Pkp2-deficient arrhythmogenic cardiomyopathy #URochesterResearch @MarioDelmar3 @DanielDWHan @Eric66867284 ahajrnls.org/3QcwoCB
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📣2 weeks left to submit your work to #CircHF for expedited consideration for #ESC2026 simultaneous publication #ESCCongress2026
Presenting at @escardio #ESCCongress 2026? Submit your work by June 22 for expedited consideration for simultaneous publication in #CircHF & maximize the visibility and impact of your research. ahajournals.org/esc #cardiotwitter #ESCCongress2026 #ESC2026
Presenting at @escardio #ESCCongress 2026? Submit your work by June 22 for expedited consideration for simultaneous publication in #CircHF & maximize the visibility and impact of your research. ahajournals.org/esc #cardiotwitter #ESCCongress2026 #ESC2026
Win ratio analyses support primary DIGIT-HF findings and clarify the contribution of clinically relevant outcomes @JBauersachsMD @DrV_Mann @AndreasJ_Rieth ahajrnls.org/4uPMH7x
New starts of ARNI and MRA, but not SGLT2i or beta-blockers associated with early reductions in PAP in HF patients across the EF spectrum enrolled in GUIDE-HF @AniqueDucharme @shelleyhallmd @MRMHeart1102 @mrchrtfaildoc @akshaydesaimd ahajrnls.org/43oirEV
Short-term temperature fluctuations trigger ADHF admissions, with distinct risks across hemodynamic phenotypes @kob @KitanoMd @shinakito @blackjtaka ahajrnls.org/4vfzNiO
Hyperventilation and venous pooling as possible mechanisms underlying dyspnea with preload insufficiency #integratedcareinstitute @ClevelandClinic ahajrnls.org/4docQ7c
Center variability in accepting 1st good heart donor match explains national racial disparities in donor heart acceptance @mcolvin89 @ShannonMDunlay @RyanTedfordMD @SelmaFMohammed @KBreathettMD @IUMedSchool ahajrnls.org/42Lx056
Structural racism drives disparities in advanced HF care. New state-of-the-art review in Circ:HF outlines solutions. #HF #Statistics #Access ahajrnls.org/4nrCUl4
Tolerogenic dendritic cells may help sustain pediatric heart transplant tolerance by suppressing alloreactive T-cells via TGF-β ahajrnls.org/4fqiVBg
Bile Acids, Mitochondria, and Myocardial Stiffness: A Shared Mechanism in Fontan Circulation and Metabolic Dysfunction-Associated Steatotic Liver Disease @sasha_opo @RichKrasuskiMD @AshishHShah3 ahajrnls.org/4uGTRKL
A roadmap for gene therapy in inherited cardiomyopathy: delivery platforms, genome editing, targets, and trials @radhikawal @MGBResearchNews ahajrnls.org/48RvWjy
How trustworthy AI and big data are shaping the future of heart failure care: opportunities and challenges @mamouei @fwasselbergs ahajrnls.org/433u17X
Circ: Heart Failure retweeted
CardioTTRansform baseline characteristics presented at #HeartFailure26! Great work as usual by @MathewMaurer @escardio Largest trial in ATTR CM with widespread use of stabilizers and more SGLT2i than other studies. Comparison with other trials seen in the tagged pictures. We appear to have a cohort more similar to ATTRIBUTE CM in disease severity. HELIOS B still has the healthiest population. Copublished in @CircHF
Circ: Heart Failure retweeted
Rationale and Design of CARDIO-TTRansform, a Phase 3 Trial of Eplontersen in Transthyretin Amyloid Cardiomyopathy CARDIO-TTRansform is fully enrolled, with 1432 randomized participants who were dosed with study drug or placebo. As the largest transthyretin amyloidosis with cardiomyopathy study to date, it will evaluate whether eplontersen improves cardiovascular outcomes in patients receiving locally available standard of care, including TTR stabilizers. @MasriAhmadMD @CircHF @CircAHA @gcfmd @SJGreene_md @AndrewJSauer ahajournals.org/doi/10.1161/CI…
Simultaneous Publication w/ #HeartFailure26 by Gunnthorsdottir et al in @CircHF: 📝Medication adherence in HF is shaped by routines, diuretic burden, psychosocial needs, and care continuity, not motivation alone. ➡️ahajournals.org/doi/10.1161/CI… @AHAScience
Simultaneous Publication w/ #HeartFailure26 by Maurer et al in @CircHF: 📝CARDIO-TTRansform is designed to evaluate whether eplontersen improves cardiovascular outcomes in patients with ATTR-CM ➡️ahajournals.org/doi/10.1161/CI… @AHAScience
Myosin ATPase Inhibition Relieves the Energetic Burden in Skeletal Myofibres of Patients With Heart Failure With Reduced Ejection Fraction @hbotker @LabBowen ahajrnls.org/42sHiXw
Vasoactive treatment in cardiogenic shock varies widely across CICUs, driven by patient-level factors and institutional practice patterns @TIMIStudyGroup @DrRobRoswell @ICUDocAP @TIMIStudyGroup ahajournals.org/doi/10.1161/CI…
Sacubitril/valsartan lowers BP; ANP drives early effects, while bradykinin contributes modestly during chronic HF therapy @adina_turcu @vumchealth ahajrnls.org/4t50eGL
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