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Most people think the psychedelic experience is what heals. They're wrong. It's what happens in the days and weeks AFTER that determines everything. In 2023, Gül Dölen's lab at Johns Hopkins made a discovery that should reshape how every practitioner thinks about their work: MDMA, psilocybin, LSD, ketamine, and ibogaine all reopen the social reward learning critical period, those rare developmental windows when we learn how to bond, trust, and adapt. Our brains were once thought to close these windows by age 26. Turns out, psychedelics hand us the key to unlock them again. Here's what makes this research so compelling: Different compounds hit different receptors — 5-HT2A, NMDA, KOR — yet they converge on the same outcome: reopening critical learning windows. It's not the trip that heals. It's the open state. And each substance opens that window for a different duration: → Ketamine ≈ 48 hours → Psilocybin ≈ 2 weeks → LSD ≈ 3 weeks → Ibogaine/5-MeO-DMT ≈ 4 weeks This isn't chaotic hyperplasticity. It's metaplasticity, a refined readiness to rewire. Dölen's team found oxytocin-mediated changes in the nucleus accumbens and softened extracellular matrix, which basically means the brain's scaffolding loosens so new wiring can stabilize. Think of it as a biological permission slip for transformation. But here's what most people miss: this window is time-sensitive. During the open state, new behavioral habits and secure attachment patterns can take root. Miss the window, and old circuitry reasserts itself. Most people don't realize how critical the days and weeks AFTER a session really are. This is exactly why we built our Practitioner Training at the Psychedelic Coaching Institute the way we did. If the medicine opens a window, then the practitioner's job is to help clients make the most of it before it closes. That means designing protocols around windows, not just sessions. It means mapping dose → duration → practice. Tracking behavior, HRV, mood, and relational change weekly. The aim isn't to chase peak experiences. It's to facilitate durable rewiring through intentional repetition in the open state. This is the next era of psychedelic work: utilizing microdosing, nervous system training, and intentional practice to expand the learning window. The medicine opens it. Your discipline keeps it open. That's how insight becomes identity. For practitioners ready to work at this level, our next PCI cohort (kicking off February 19!) is where this science meets real-world application. What are your thoughts on how to design integration around the critical period window?
@vale_regalito Felicidades por tu logro! Y te deseo lo mejor para esta nueva etapa! 🤍🥹✨🌟🙌🏻👏🏻🪽
Two Visions for Psychiatry: The Future of Psychotherapy A psychiatrist argues "Psychotherapy Training Shouldn’t Be Part of Psychiatry" training; emphasizing the importance of mastering biological skills. He sees psychotherapy as a niche, best left to other professionals. I see psychotherapy as the core of human connection—a vital tool for understanding patients’ stories, building trust, and fostering healing. It’s not just about symptoms; it’s about meaning, narrative, and living authentically. Should psychiatrists learn psychotherapy? I think so. IMO, the future of psychiatry depends on integrating science with humanity.
Each new DSM diagnosis (we are at around 370 right now) creates an entirely new market for psych-drug consumption. This is why the drug companies love DSM: it's an ever-reliable driver of profit.
The brain’s action-mode network and default-mode network counterbalance each other as yin and yang. 🧵1/10
@vale_regalito Qué bueno que te ayuden! Me alegro mucho y éxitos con los que vienen! 🙌🏻🥹
@baeles2 🥹🥹🫶🏻💓 uno bravo encima. Abrazo enorme! 🫰🏻
a otter puts her pup on her belly so they can nap together 🥺
@MoniChuch @Carito_lacoya Aww que lindo! Me alegra que te gusten 🥹🫶🏻⭐️✨ abrazo enorme! Gracias por el mensajito
Cheetahs don't roar, they meow and purr like house cats.
Creemos que ayudando al resto vamos a ayudarnos a nosotros mismos cuando en realidad la mejor forma de ayudar al resto es empezar por ayudarnos a nosotros mismos
@narizdechanch0 Si es el mismo detergente de siempre… Con uña de gato Dice..Y donde están las plantaciones de aloe Vera? La concha de su madre. Si yo ando por todos lados
ONI @OniSilverMorph
90K Followers 3K Following Licenciado en turismo 🌎✈ Pokémon Fan 🤩 Si no puedo convencer al Cielo, moveré a los Infiernos. TCGPocket: 6267615042094305
Arianiter @fedege_
32K Followers 512 Following
Lucas Vigiani @lucasvigiani
84K Followers 447 Following Social Media Head @clarincom | Tengo un perrito salchicha | Periodista
Lani @lani_kito
81K Followers 593 Following No soy gato persa, soy Gato Mersa - Vicepresidente de SindiGato
Diel🆗 @Diel0k
134K Followers 2K Following Hombre Cis genero. Mis pronombres: He/His/Him/El/Ellos. Si soy el medico de Lozano. Miro tele de aire
El Teque @Dariodzs
69K Followers 1K Following Se les complicaba decir mi nombre y me bautizaron Tequeño // Youtube Premium Activist // Fui una Swiftie Mojada 9/11 // ig: @dariodzs
ceroambiente 💚+�... @SuperNariz
49K Followers 1K Following Tengo la nariz torcida. Argentino ❤️. Con un amigo creamos #arta. El user es ironía.
In my congenial era �... @FedeOrgam
48K Followers 1K Following From Argentina to ConQueer the Galaxy DJ and performer 🎚🎛🎚 #peaktime #Trance #Acid #Techno
Maxi @emedemaxi
33K Followers 2K Following un negro puto, poeta y peronista | escribo en https://t.co/N4IVguF4sE
Fernando Ramos @FernandoRms_
18 Followers 202 Following Sé agradable, el mundo es una ciudad pequeña☝🏻
personaje @quepersonaje87
19 Followers 303 Following
Rubén Cázarez @Rubencazarez14
52 Followers 880 Following
ces.leo @LeoCesar976
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Gas alucinógeno @GAlucinogeno
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Luis @Luis7r5p
1 Followers 120 Following
SSDDP @stopandstares
104 Followers 1K Following
feche17 @feche17
12 Followers 556 Following
mickp @PiNkhyL
59 Followers 1K Following
Vicky @vickyarhalli567
192 Followers 4K Following Baked pemmican pemmican-pemm, meats meat-meat-mashing—Native nips nibble.
Ângelo Theodoro @angelo_theodoro
242 Followers 2K Following Radialista desde o principio do mundo.Arq e designer de int. Aprovado em Psicologia pela Anhanguera .Futebol minha paixão. Amo ciameses. Amo computação. ✌🎶
Bypa Pallavi @BypaPallavi
165 Followers 4K Following Tuned serpent serpents, curves curved and contrabass. Baroque beasts.
Manuel Conde Macias @CondeMacias
71 Followers 2K Following Brewed kombucha in glass jars on the counter, fizz building like tiny celebrations in fermented tea.
muscle men @musclemenhot
84 Followers 2K Following
Itadori @Itadori_15
1 Followers 385 Following
Ranjithkumar @Ranjith14598734
162 Followers 4K Following Foraged lamb's quarters lambed, quarters quartering quick. Seeds seeded, greens good.
Nisper @Kiruna33
3 Followers 66 Following
Iván Manuel Blázque... @IvnAetos
23 Followers 675 Following
Bad Boy.... @incestorboy1
2K Followers 5K Following ONLY OVER 18 YEARS OLD, DELICATE CONTENT.....🔞🛑🔙 RELATIONSHIPS BETWEEN INTERGENERATIONAL MALE, MOSTLY FILIAL-GAYSEX EXPLICIT CONTENT..... NO MESSAGES.
JL @JotaBD20
16K Followers 1K Following Catalan | Anti-imperialist leftist | Beatnik | Software developer 👾 Into movies, games & hairy men. CAT-ES-EN
Johana Yamileth @JohanaYami34322
0 Followers 12 Following
mora @tuschicashots
2 Followers 75 Following
Gerardo Suarez @GerardoSua14534
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anny @lopez_mart77320
1 Followers 18 Following
suncar @suncar024
11 Followers 477 Following
Lulu @gimenez_me94098
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Sandra Mary @SandraMarr48561
91 Followers 1K Following
Susan @BlackshepSusan
5K Followers 5K Following I will not be quiet. No more 🤐 Campaigner to raise awareness that psychiatric drugs are not as safe and effective as advertised. There are better ways.
Marc Tibber @MarcTibber3
8K Followers 5K Following Lecturer @UCL_DClinPsy & Senior Clinical Psychologist. Research social factors in YP's MH. Scientific hippy. Views my own. RT=/=endorsement. #shitscomplicated
Dr Nagina Khan @DrKhan_do
6K Followers 7K Following Ph.D Senior Clinical Research Fellow in PC, Director NIHR INSIGHT Program, SFHEA,@UniKent. Associate Editor @BMJMentalHealth, Senior Fellow @BMJLeader
ONI @OniSilverMorph
90K Followers 3K Following Licenciado en turismo 🌎✈ Pokémon Fan 🤩 Si no puedo convencer al Cielo, moveré a los Infiernos. TCGPocket: 6267615042094305
Arianiter @fedege_
32K Followers 512 Following
Lucas Vigiani @lucasvigiani
84K Followers 447 Following Social Media Head @clarincom | Tengo un perrito salchicha | Periodista
Lani @lani_kito
81K Followers 593 Following No soy gato persa, soy Gato Mersa - Vicepresidente de SindiGato
Diel🆗 @Diel0k
134K Followers 2K Following Hombre Cis genero. Mis pronombres: He/His/Him/El/Ellos. Si soy el medico de Lozano. Miro tele de aire
El Teque @Dariodzs
69K Followers 1K Following Se les complicaba decir mi nombre y me bautizaron Tequeño // Youtube Premium Activist // Fui una Swiftie Mojada 9/11 // ig: @dariodzs
ceroambiente 💚+�... @SuperNariz
49K Followers 1K Following Tengo la nariz torcida. Argentino ❤️. Con un amigo creamos #arta. El user es ironía.
In my congenial era �... @FedeOrgam
48K Followers 1K Following From Argentina to ConQueer the Galaxy DJ and performer 🎚🎛🎚 #peaktime #Trance #Acid #Techno
Maxi @emedemaxi
33K Followers 2K Following un negro puto, poeta y peronista | escribo en https://t.co/N4IVguF4sE
Alejandro Sergi @alejandrosev10u
18K Followers 1 Following
Chaz Firestone @chazfirestone
20K Followers 944 Following Cognitive scientist @JohnsHopkins. 🇨🇦 also: https://t.co/96gKNz0VWF
Kording Lab 🦖 @KordingLab
74K Followers 3K Following Konrad kording, @Penn Prof, deep learning, brains, #causality, rigor, https://t.co/tTJW05RRfa, https://t.co/qf7ZHxjaK1, Transdisciplinary optimist, Dad, Loves outdoors, 🦖
Thomas Yeo @bttyeo
12K Followers 1K Following brain imaging, machine learning, neuroscience, brain disorders
WashU Medicine Neurol... @WashUNeurology
3K Followers 335 Following We strive to provide outstanding clinical care, train leading neurologists and scientists of the future and to serve as an international leader in Neurology.
Michael Fox @foxmdphd
7K Followers 445 Following Neurology Prof and Neuroscientist focused on brain imaging and brain stimulation @harvardmed @brighamWomens @brain_circuits
Lucina Uddin @LucinaUddin
14K Followers 6K Following Edgy cognitive neuroscientist @ucla (she/her) 🇧🇩🧠🏀 Also at @lucinauddin.bsky.social
Luiz Pessoa @PessoaBrain
50K Followers 1K Following Neuroscientist interested in cognitive-emotional brain Author of The Entangled Brain (MIT Press); The Cogitive-Emotional Brain Neuroscience & Philosophy Salon
WashU @WashU
47K Followers 839 Following Where people matter, and serious work is done. Share your experiences with #WashU and look for @ WashU on Instagram and on TikTok.
Erik Musiek @ErikMusiek
3K Followers 437 Following Neurologist/scientist at Washington University in St Louis. Circadian clocks, glia, neuroinflammation, neurodegeneration. Alzheimer’s doc, soccer/track dad.
WashU Med Taylor Fami... @WashUNeurosurg
6K Followers 643 Following Training tomorrow's leaders in neurosurgery, discovering promising advances in neuroscience research and providing world-class patient care.
Joshua Siegel @realJoshSiegel
8K Followers 232 Following Neuroscientist, Psychiatrist, Father, Human, Philomath. Good science is careful. Great science is playful.
Om Prakash, MD @ompsychiatrist
8K Followers 825 Following Prof. Om Prakash, MD | Psychiatrist | Geriatric | ECT Specialist | 25+ years advancing evidence-based care with compassion | Mental Health Advocate | Views own
Bryan Shapiro MD, MPH @BShapiroMD
212 Followers 24 Following Psychiatrist at UC Irvine Medical Center
Isomorphic Labs @IsomorphicLabs
59K Followers 82 Following Solve all disease. Developing and applying frontier AI to unlock deeper scientific insights, faster breakthroughs, and life-changing medicines.
Jesse Morse, M.D. @DrJesseMorse
190K Followers 2K Following Health Optimization utilizing Peptides & Stem Cells. Board-certified: Sports & Family medicine. @stackapp. Sports Injuries for @InjuryExpertz.
Andrew Gallimore @alieninsect
46K Followers 789 Following Tokyo. 作家. Neurobiologist, pharmacologist, writer on psychedelics, especially DMT. "Death by Astonishment", OUT NOW: https://t.co/F25GjiDSxu
Julie Holland, MD @BellevueDoc
16K Followers 2K Following harm reduction psychiatrist, author, mom musician, MDMA & cannabis researcher, medical advisor to MAPS, Palo Santo ++ GOOD CHEMISTRY: The Science of Connection.
Dr Peter Sjöstedt-Hu... @PeterSjostedtH
24K Followers 3K Following Philosopher of Mind and Metaphysics (Whitehead—Nietzsche—Spinoza—Psilocybin)|Lecturer (Uni of Exeter)|Co-director of BC|TEDx Talk: https://t.co/TEE6id7NeY ᛏ
Alex Grey @alexgreycosm
117K Followers 1K Following I am a psychedelic visionary artist, co-founder with my wife Allyson, of the Chapel of Sacred Mirrors, CoSM.
Stephen Ferris @StephenDFerris
42K Followers 46K Following Visionary Artist/// Self-Taught/Intuitive
Dr. Rick Barnett, Psy... @drrickbarnett
18K Followers 3K Following Licensed Psychologist #Addiction #MentalHealth - Fun, friendly, co-founder Psychedelic Society of Vermont, + CARTER, Inc. https://t.co/pWT4llpKBo
👾 𝐀𝐥𝐢𝐞... @APsychedelics
14K Followers 703 Following Bored? Come chat with fellow psychonauts in my Super Psychedelic Hæven community on Telegram! Link below ⬇️
Psychedelics Today @PsydelicsToday
43K Followers 946 Following Psychedelics Today is the planetary leader in psychedelic education, media, and advocacy.
Captain Pleasure, And... @algekalipso
43K Followers 6K Following Views of a Transhuman neo-Buddhist from the future on sociology, artificial intelligence, mathematics, philosophy, neonoir film, and the post-singularity era.
Vivid Void @vividvoid
69K Followers 1K Following I believe in everything. Nothing is sacred. I believe in nothing. Everything is sacred.
Taylor Sterling @FatherMcKennaa
52K Followers 1K Following psychedelic history, culture, and harm reduction
Dalton (Analyze & Opt... @Outdoctrination
142K Followers 449 Following Biomolecular Engineer. If YOU want personalized help from me with your health goals, book a free call here: https://t.co/Lr8dZJtOkn
Paul F. Austin @PaulAustin3w
17K Followers 542 Following Built the most trusted platform in psychedelics (@thirdwaveishere). Trained 500+ practitioners. I post the research most people aren't reading.
La Moscatito @lamoscatito
3K Followers 4K Following Extracto de charlas de mariconas : chismes, política , puterio, bultos, cuernos, puterio y cosas que no les interesan a nadie .
elvulpixx @AnandoGustavo
284 Followers 9 Following
Bryan Johnson @bryan_johnson
1.8M Followers 663 Following Conquering death will be humanity’s greatest achievement.
Murad Kane @muradboii
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R S @RamiSep87
189 Followers 1K Following Emprendedor y estudiante de Medicina. Boca, Celtics, Patriots y Roger Federer.
JL @JotaBD20
16K Followers 1K Following Catalan | Anti-imperialist leftist | Beatnik | Software developer 👾 Into movies, games & hairy men. CAT-ES-EN
plátano canario 🇮... @Littobm
33K Followers 566 Following balonmano 🤾🏼♂️ | me da igual el 50% de lo que me dicen, al otro 50% no le presto atención. uzumaki🐐 sextuittero 👻📸🔞













































