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Children and adolescents in higher fitness quantiles exhibited lower cumulative incidences of anxiety disorders, depressive disorders, and ADHD, finds nationwide cohort study encompassing 1.9 million participants in Taiwan. ja.ma/4bi9Fu2
“Depression may be due to many factors. Genetics can put certain people at risk for depression. Stressful situations, physical health conditions, and medications may contribute. … All of these can affect which treatment would be best to use.”
“With the power of rapid data analysis, whether it be from genomes; microbiomes, bacteria and viruses in our guts; or even wearable devices that collect data such as the number of steps, blood oxygen, and more, AI can find patterns and clues to our health in all of this data.”
“With the power of rapid data analysis, whether it be from genomes; microbiomes, bacteria and viruses in our guts; or even wearable devices that collect data such as the number of steps, blood oxygen, and more, AI can find patterns and clues to our health in all of this data.”
'E-cigarettes have failed to achieve their initial goals—both from a scientific and a health care perspective. Realistically, tobacco/e-cigarette companies have fully achieved their goals. Although the number of tobacco smokers declined, the number of e-cigarette users has…
“Dr. Greicius of Stanford said he believed the totality of data coming from the donanemab, lecanemab, and aducanumab clinical trials points to the limitations of anti-amyloid therapy.”
“Dr. Greicius of Stanford said he believed the totality of data coming from the donanemab, lecanemab, and aducanumab clinical trials points to the limitations of anti-amyloid therapy.”
“‘The evidence suggests that lipid metabolism is a driving mechanism for Alzheimer’s disease. There are many drugs that target lipid metabolism in other body systems, such as in the liver, so we might be able to change this system quite dramatically using tools we already have.’”
“‘The evidence suggests that lipid metabolism is a driving mechanism for Alzheimer’s disease. There are many drugs that target lipid metabolism in other body systems, such as in the liver, so we might be able to change this system quite dramatically using tools we already have.’”
“[K]nown risk factors for Alzheimer's, including high cholesterol, hypertension, & obesity, along with lifestyle habits & certain medications … are routinely recorded in EHRs, & the researchers … [evaluated] whether this information could help predict Alzheimer’s effectively.”
“[K]nown risk factors for Alzheimer's, including high cholesterol, hypertension, & obesity, along with lifestyle habits & certain medications … are routinely recorded in EHRs, & the researchers … [evaluated] whether this information could help predict Alzheimer’s effectively.”
“Adults with persistent COVID-19 symptoms are about twice as likely to report psychiatric problems such as depression, anxiety, or cognitive difficulties versus other adults, reports a study in JAMA Network Open.”
“Adults with persistent COVID-19 symptoms are about twice as likely to report psychiatric problems such as depression, anxiety, or cognitive difficulties versus other adults, reports a study in JAMA Network Open.”
“‘This study suggests that TREM2 displays a dual activity in microglia, which should be carefully considered when contemplating TREM2 as a therapeutic target.’”
“‘This study suggests that TREM2 displays a dual activity in microglia, which should be carefully considered when contemplating TREM2 as a therapeutic target.’”
“Findings suggest greater collaboration between geriatricians and eye care providers may be warranted to assess and address fall risk in older adults with [vision impairment].”
“Findings suggest greater collaboration between geriatricians and eye care providers may be warranted to assess and address fall risk in older adults with [vision impairment].”
Brain Blood Flow Syncs with Visual Stimuli Researchers developed a new method to observe and monitor blood vessel dynamics in the mouse brain, revealing that visual stimuli can synchronize blood flow, enhancing brain function. This study used visual patterns of moving stripes…
The latest #neuroscience tracks where #Alzheimers disease begins and how it progresses scientificamerican.com/custom-media/d… via @sciam #dementia #health #science
Great recommendations for preventing falls:
79.3% of psychiatrists recommended immediate antidepressant treatment for a person with depression, but only 39.1% would follow that recommendation themselves. 🧵1/10
An #NIAfunded study found that measures of epigenetic age, such as DNA methylation, can aid prediction of #aging-related health outcomes and death. Learn more about the study here: go.nia.nih.gov/3Uhi7nn
“Clinical decision-making on antidepressant treatment during pregnancy, particularly selective serotonin reuptake inhibitors (SSRIs), is challenging, as both prenatal SSRI exposure and maternal depressive symptoms may be associated with negative outcomes in offspring.”
“Clinical decision-making on antidepressant treatment during pregnancy, particularly selective serotonin reuptake inhibitors (SSRIs), is challenging, as both prenatal SSRI exposure and maternal depressive symptoms may be associated with negative outcomes in offspring.”
“Despite the improved predictive capability of multivariate compared with univariate neuroimaging markers, no informative individual-level MDD biomarker—even under extensive ML optimization in a large sample of diagnosed patients—could be identified.”
“Despite the improved predictive capability of multivariate compared with univariate neuroimaging markers, no informative individual-level MDD biomarker—even under extensive ML optimization in a large sample of diagnosed patients—could be identified.”
Are you a researcher interested in learning about the mechanisms of blood-brain barrier transport, how they’re affected in aging & #Alzheimer’s, & how they can be utilized to enable drug delivery to the Central Nervous System? Check out this NIA workshop: nia.nih.gov/research/dn/wo…
Caregiving Guide: 79 tips for In-Home Safety carex.com/blogs/resource… #Alzheimers #dementia
Save the date! On April 25th, don't miss NIA’s webinar on Alzheimer’s disease risk across diverse populations. Explore how to use the Health & Aging Brain Study – Health Disparities infrastructure in your #dementia research. Register today to learn more: go.nia.nih.gov/3VIX1PY
Katelyn Zinzow @KZinzow17086
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12 Followers 3K FollowingDebra Senk @debra_sen
57 Followers 5K FollowingChristina Williams @AngelaJens39884
260 Followers 3K Following Tasha specializes in adult products (silicone dolls) and provides you with the best quality service, please visit the Telegram channel for details.Liza Kmetz @KmetzKm
56 Followers 5K FollowingJacquiline Izaguirre @IzaguirJacquili
16 Followers 3K FollowingMarion Savko @MarionSavk27430
86 Followers 5K FollowingMichael Young @MJYoung_MD
2K Followers 1K Following Neurologist at @MGHNeurology @HarvardMed. Devoted to improving care systems through neurotechnology, neuroethics and neuroscience.Menna Geitz @MeGeitz
72 Followers 5K FollowingMiranda Hankel @hank_miran
59 Followers 5K FollowingChristin Lalim @lal_christ
77 Followers 5K FollowingTessa Arriola @ArriolaTes40805
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2 Followers 21 FollowingMolly Brendon @BrendoMoll
17 Followers 3K FollowingCamelia Corrick @CorriCame
42 Followers 5K FollowingMelodi Alcaoa @alcaoa50954
77 Followers 5K FollowingSky Wickersheim @SkyWickers47475
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44 Followers 5K FollowingCataleya Vanaman @CataleVanama
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40 Followers 5K FollowingBari Hakkila @hakkila14477
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41 Followers 5K FollowingEden Rudi @EdenRudi17469
58 Followers 5K FollowingKati Kennet @kati_ken
42 Followers 5K FollowingTillie Topping @TilliToppin
28 Followers 5K FollowingStephani Kus @KusStephan76950
80 Followers 5K FollowingRichard @Sheauez154992
441 Followers 5K Following See the world on the road, and get to know yourself on the way!Mildred @hetrickmildred2
104 Followers 3K FollowingGoughd @Goughd274872
9 Followers 1K Following The flowers and leaves are fragrant, and the beautiful scenery lasts morning and nightAdelaide Vega @adelaide94334
104 Followers 3K FollowingSusan Prasad @SusanPrasa67070
104 Followers 3K FollowingAlison Fisher @AlisonFish70537
106 Followers 3K FollowingZimmer Lab @zimmerneurolab
3K Followers 2K Following Multidisciplinary lab, at @ufrgsnoticias, interested in understanding neuron-to-astrocyte communication in neurodegenerative disorders 💜 | PI: @erzimmerCTAD @CTADconference
3K Followers 368 Following The Clinical Trials on Alzheimer's Disease conference (CTAD) is a meeting focused entirely on Alzheimer’s Disease Therapeutic TrialsJason Karlawish @jasonkarlawish
4K Followers 578 Following Physician/writer @Penn, codirector @Penn_Memory Center. Beginning Feb 1, '24 I'm on a writing break and so quiet here. Please visit my website to message me.Michael Young @MJYoung_MD
2K Followers 1K Following Neurologist at @MGHNeurology @HarvardMed. Devoted to improving care systems through neurotechnology, neuroethics and neuroscience.Center for Mental Hea.. @Cemhri
1K Followers 831 Following Our vision is to become a leading centre of excellence in Africa providing essential and up to date News, Research, Data and Services in Mental Health.Sylvia Villeneuve @sylv_villeneuve
3K Followers 1K Following Associate Professor Department of Psychiatry, McGill University Neuroimaging, MRI, PET, Alzheimer's diseaseChetelat's Lab @ChetelatLab
1K Followers 732 Following Multimodal Neuroimaging and Lifestyle in Ageing and Alzheimer's Disease | @Neuropresage | @InsermNIA Division of Behav.. @NIA_BSR
2K Followers 396 Following Official account of National Institute on Aging's Division of Behavioral and Social Research (BSR). Privacy policy: https://t.co/HWVGVtcXG1Shea J Andrews @SheaJAndrews
692 Followers 625 Following Assistant Professor investigating the genetic epidemiology of Alzheimer's disease at the University of California San FranciscoKarolinska Institutet @karolinskainst
41K Followers 184 Following News from the Swedish medical university Karolinska Institutet (KI).Sebastian Palmqvist @SebastianPalmqv
669 Followers 35 Following Consultant neurologist, Associate professor, Memory Clinic, Skåne University Hospital and Clinical Memory Research Unit, Lund UniversityWashington U. Med @WUSTLmed
26K Followers 2K Following Washington University School of Medicine – advancing human health through research, education and patient care. Teaching hospitals: @STLChildrens, @BarnesJewishADI @AlzDisInt
18K Followers 953 Following Alzheimer's Disease International (ADI) is the global voice on dementia. We raise awareness by supporting Alzheimer associations and individuals worldwide.Wake Forest Alzheimer.. @WakeADC
708 Followers 709 Following Working to advance our understanding of #Alzheimer's disease through studying risk factors and novel interventions.Alzheimer's News Toda.. @adnewstoday
604 Followers 12 Following We exist to bring you science, research and clinical news about Alzheimer's disease. We are a free digital publication dedicated to the patient community.Tribal Diagnostics @Triballab
215 Followers 166 Following Native American-owned and operated premier diagnostic lab aimed at helping improve health outcomes for tribal communities.Health Gorilla @healthgorilla
2K Followers 1K Following Health Gorilla has achieved designation as a Qualified Health Information Network. Book a demo: https://t.co/nYKraqIm1u View our API docs: https://t.co/IVJrKuVyj6Cell @CellCellPress
246K Followers 634 Following Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell Editorial team.Isaac Kohane @zakkohane
11K Followers 607 Following Computer science + Biomedicine = Medicine as a Knowledge Processing Discipline @harvardMED @HarvardDBMI Prof/Dept Chair https://t.co/6qcUd2RfDs MD/PhD @NEJM AI EICDBMI at Harvard Med @HarvardDBMI
7K Followers 682 Following Department of Biomedical Informatics at @Harvard/@harvardmed: #datascience- & #AI/#ML-powered models of clinical care to advance human health. Chair @zakkohane.AI_4_Healthcare @AI_4_Healthcare
663 Followers 944 Following #AIinHealthcare #MedTwitter #DigitalHealth #MedTech #AIinPharma #HealthcareInnovation #AIGovernance #ResponsibleAI #HealthEquity #AI 💻 🩺 💊💉🏥⚕️🩻 🚑 🗺️Journal of Pharmaceut.. @JPharmAnalysis
406 Followers 0 Following With an #impactfactor of 8.8, Journal of #Pharmaceutical Analysis is the right home for your #cuttingedge #research on any aspect of #pharmaceuticalanalysis.U-M Alzheimer's Disea.. @umichalzheimers
1K Followers 720 Following National Institute of Aging funded research center committed to memory and aging research, clinical care, education, and wellness.Women's Brain Foundat.. @womensbrainpro
8K Followers 6K Following Women’s Brain Foundation (WBF) is an international non-profit organization studying sex and gender determinants to brain and mental health.Liana Apostolova, MD,.. @ApostolovaLiana
2K Followers 650 Following Cognitive neurologist and Alzheimer's disease researcher, Indiana University Distinguished Professor, Principal Investigator of LEADS, Editor-In-Chief DADMNational Alzheimer's .. @NACCData
2K Followers 4K Following NACC collects, harmonizes, and shares Alzheimer's disease research data from 37 NIA funded Alzheimer's Disease Research Centers across the US.Wisconsin Alzheimer's.. @WAI_Alzheimers
2K Followers 865 Following Home of WI Registry for Alzheimer’s Prevention: One of the world's LARGEST & LONGEST RUNNING studies of individuals at risk for AD. RTs, links ≠ endorsement.UCI MIND @ucimind
2K Followers 1K Following Home to one of 32 #Alzheimer’s Disease #Research Centers funded by the @NIH National Institute on Aging and one of 10 California Alzheimer’s Disease CentersJAGS @AGSJournal
11K Followers 1K Following Premier journal for geriatrics clinical science, innovative models of care, and health policy that impacts geriatrics professionals and those they serve.Dr Hazel Hall-Roberts @HazelLRoberts
442 Followers 227 Following Alzheimer's disease scientist researching stem cell models of microglia at the UK Dementia Research Institute in CardiffSophie Sanford @_sophiesanford
978 Followers 1K Following Scientist @alchemabtx,🇯🇵 🇬🇧 Prev: @alzheimerssoc PhD student at @w_mcewan lab, @ukdri Cambridge @WolfsonCam, 🧫and intern @BicycleTx. Views my own.Imperial Department o.. @ImperialBrains
3K Followers 738 Following Department of Brain Sciences @imperialcollege | Part of @ImperialMed | Delivering a unique portfolio of translational research in neuroscience and mental healthDr Jo Jackson (jojack.. @jojacksonhere
1K Followers 1K Following Group leader: synapse loss in AD | multi-'omics atlas project https://t.co/w27wMtBT8O | @UKDRI @imperialbrains | love brains, synapses and microscopes | views=mineDonna Wilcock @Wilcock_v2
750 Followers 301 Following Dementia researcher at Indiana University studying biomarkers and vascular contributions to dementia including Alzheimer’s. EiC of Alzheimer’s & DementiaIndiana Alzheimer's D.. @iadrc_iu
917 Followers 876 Following The Indiana Alzheimer's Disease Research Center, established in 1991, bringing together investigators and institutional resources at IU School of Medicine.Johns Hopkins Memory .. @JH_Memory_Aging
3K Followers 3K Following A JH Alzheimer’s Disease Research & Treatment Centers collaboration sharing #Aging #Research and promoting #Brain #Health, #Memory loss & #Caregiver #Resources.Suzanne E Schindler @SuzanneESchind1
765 Followers 270 Following Assoc Prof Neurology @WashUNeurology @WUADRC | Clinical neurologist and neuroscientist dedicated to improving the diagnosis and treatment of dementia.Carry Venture Capital @carryventurecap
67 Followers 398 Following A seed-stage venture fund investing in exceptional, undervalued and overlooked founders that are building transformative companies across North Carolina.pharmalot @pharmalot
61K Followers 1K Following The latest news and views about the pharmaceutical industry, with @EdSilverman of @Statnews, ex-WSJ.. tips: [email protected]I Am Biotech @IAmBiotech
106K Followers 6K Following I Am Biotech is where biotech professionals and enthusiasts can come together and discuss the promise of biotech innovation. #BiotechScience News @ScienceNews
5.1M Followers 555 Following Covering the latest news in all fields of science. Publisher @society4science. See also @SN_Explores.Tweener Fund @TweenerFund
147 Followers 49 FollowingScot Wingo @scotwingo
10K Followers 3K Following @GetSpiffy CEO, GP at https://t.co/3p2l2vkHin and Podcast on ecomm/retail with @retailgeek https://t.co/r8xqBDfeNULasagna-Reeves Lab @LasagnaLab
544 Followers 244 Following The lab of Cristian Lasagna-Reeves, Associate Professor at @IUMedSchool Investigating cellular and molecular mechanisms of AD and other tauopathiesWisconsin ADRC @WisconsinADRC
2K Followers 1K Following Improving lives of people affected by #Alzheimers & #dementia | Early detection | Risk & protective factors | #DementiaMatters podcast | Funded by @NIHAgingThe first randomized trial of medical #AI to show it saves lives ECG-AI alert in 16,000 hospitalized patients 31% reduction of mortality (absolute 7 per 100 patients) in pre-specified high-risk group nature.com/articles/s4159… @NatureMedicine
Could digital pills improve medication adherence in persons living with dementia? A qualitative study. #geriatrics agsjournals.onlinelibrary.wiley.com/doi/10.1111/jg…
Microplastic exposure reduced gene expression related to brain development and caused depression/anxiety-like behaviour in mice. sciencedirect.com/science/articl…
In an incredible presentation, Dr. @Pamlukasewicz from @PittTweet 🇺🇸 showed her latest findings on the clinical utility of plasma p-tau217. #AAICNeuro #AAICNeuroPOA
Cool new paper in Cell that ties together two fundamentals of cancer biology: cancer cells have high levels of lactate (due to the Warburg effect), and almost always find a way to inactivate the cell's best tumour suppressor, p53 Zong et al. found that lactate, from the…
The biomarkers field has predominantly focused on protein aggregates and neurodegeneration, but now it is time to embrace the heterogeneous and dynamic response of astrocytes ⭐ as a very promising biomarker target.
The lack of disease specificity of🩸GFAP should not be regarded as a limitation but as a strength, also serving as a screening biomarker. The @alzassociation workgroup is proposing GFAP as a biomarker of "inflammation"; thus, the work by @psanjua and colleagues is very timely! +
However, GFAP could definitely play a role as a prognostic biomarker in AD, as demonstrated in a recent large-scale proteomics study in @NatAging nature.com/articles/s4358… 🧶👇
In sum, 🩸GFAP reflects astrocyte reactivity to brain pathology and is one of the most promising biomarkers for AD and related dementia. 🧶👇
Specifically, 10 of the top 15 most non-specific symptoms in the DSM-5 appeared in the diagnostic criteria for MDD. 7/10
Perhaps MDD symptoms are psychological responses to stress, similar to how fever – a symptom that also cuts across numerous diagnostic categories – reflects an inflammatory response to cell damage or stress. 8/10
The pervasiveness of MDD symptoms throughout the DSM-5 likely hampers diagnostic accuracy through misattribution of symptoms in other diagnoses to MDD, and inflation of the rates of comorbidity due to symptom overlap with other diagnoses. 9/10
"Thanks to Congress’ investment in the Human Genome Project decades ago, many of the approximately 10,000 rare diseases, which impact at least 30 million Americans, can now be treated with new gene-editing and gene therapy technologies." -- @DrCaliff_FDA
Musical Memories Cafes provide a space for joy and connections amidst the challenges of Alzheimer's and dementia. @bbonakda spoke to @TheBuffaloNews about the therapeutic potential of music and community. Read more: buffalonews.com/news/local/the…
@MadhavThambiset @EWidera @smead2 @ajlees @ProfRobHoward @MemoryDoc @dr_shibley @LonSchneiderMD @seb_walsh @_michael_scholl @VincentPlanche @StefanoSensi14 @AlbertoEspay @nvillain_alz @KasperKepp @PhilAlz @Gill_Livingston @DrTFromKC @jfballenger @jasonkarlawish @JamesRuFletcher @AdamMBrickman @ManlyEpic @SFAckley @FortuneMagazine @TIME @ErinMPrater @TIMEMagazineRS @FT @hannahkuchler @CTADconference @NIH @alzassociation @howard_gleckman @AmerGeriatrics @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @US_FDA @NICEComms @RaymondKoopmans @MaastrichtU @Kariem_Ezzat @DrBenUnderwood1 @NHSEngland @ObserverUK @FeiiXiong @sducharme66 Interventions to decrease social isolation for people with dementia: A systematic review via @wang_zuyu et al
Spinal Cord Learns and Remembers Movements Autonomously A new study reveals the spinal cord's own learning and memory capabilities, independent of the brain. This research could transform rehabilitation methods for spinal injury patients. neurosciencenews.com/spinal-cord-le… 2/3
“I know Alzheimer’s can destroy careers, relationships, and every day it robs me of more and more of my memories. But I stand here today to tell you, my diagnosis does not define who I am. I am living my best life with MCI, and using every opportunity to share my story as my way…
We know navigating dementia care is stressful, and everyone deserves support. This partnership will help more people in more communities access the personal navigation support they need in the healthcare setting.
We are excited to share that a new Alzheimer’s Association partnership, the Dementia Care Navigation Service, powered by Rippl and the Alzheimer’s Association, has been selected as a provider for the Guiding an Improved Dementia Experience (GUIDE) Model. bit.ly/3VIw9jd
Early diagnosis of dementia is vital and quick blood tests have the potential to catch this condition sooner in thousands of patients. That's why we are investing in world-leading trials to ensure any new treatment can be rolled out safely and rapidly. thetimes.co.uk/article/thousa…
New Research: Precise and low-power closed-loop neuromodulation through algorithm-integrated circuit co-design: Implantable neuromodulation devices have significantly advanced treatments for neurological disorders such as Parkinson’s… frontiersin.org/articles/10.33… #Neuroscience