Defining LOT in #RWD is a critical challenge for biopharma researchers & sponsors, however, precision is paramount.
In a new blog, Arun Sujenthiran & Nikola Dolezalova detail the validated methodology we use to operationalize LOT from RWD.
resources.flatiron.com/real-world-evi…
In addition to launching six new hematology panoramic datasets, Flatiron will be presenting 12 pieces of research at this year’s #ASH25.
Join us at booth #1111 more about our presence at this year’s ASH: events.flatiron.com/ash2025
Sources:
1. Frontiers in Oncology (2025) – Real-world evaluation of adjuvant capecitabine in early TNBC
frontiersin.org/journals/oncol…
2. ecancer (2025) – Baseline NLR >2 predicts long-term outcomes in early TNBC
doi.org/10.3332/ecance…
TNBC insights from this week’s real-world data:
pCR → best outcomes
No pCR → capecitabine didn’t add much in practice
NLR >2 → strong risk signal even before treatment
Simple take:
RWD exposes the gap between expected benefit and actual benefit.
#Oncology#RWE#HEOR
RWD confirms the story: talquetamab performs in practice, not just in trials.
Real-world performance matching clinical outcomes strengthens confidence — especially in heavily pre-treated RRMM.
🔗 nature.com/articles/s4140…
A single odd event looks harmless.
Across a full cohort, it rewrites your entire understanding of the disease.
RWD doesn’t exaggerate problems — it exposes the ones you never knew existed.
#RealWorldData#OncologyAnalytics#RWE
Data is constant.
Definitions aren’t.
Most disagreements in analytics aren’t about the numbers — they’re about the meaning we assign to them.
#OncologyAnalytics#RWE#DataScience
Video credits (YouTube):
· 60 Minutes: What's next for AI at DeepMind, Google's artificial intelligence lab | 60 Minutes
· 60 Minutes: Google DeepMind CEO demonstrates world-building AI model Genie 2
Images: · apidays.typeform.com/to/i1MPEW
Watching The Sabarmati Report, it felt heavily influenced by politics. The real truth behind such events is hard to know. What’s troubling is how every political party uses these events, true or not, to shape public opinion.
#TheSabaramatiReport
Talk about leveling up - Back in old India, you needed a license to own a radio. I see future kids with spaceships casually parked on their rooftops. 📻➡️🚀
Will digital connections replace physical ones?
A big NO – the feel of physical presence is hard to replicate with technology. Digital connection won't replace face-to-face, but they help fill the gap when our social demands exceed the no. of physical connections we can manage
Everyone takes a different amount of years to stop giving af about what everyone else thinks.
And if you’re gonna get there eventually, you might as well start today and enjoy the benefits for longer.
Could we see Siri take on a visual form in upcoming Apple Vision Pro updates? Imagine a 3D Siri right in your virtual space—how would it reshape our tech interactions? #AppleVisionPro#Siri#AR
Progress is often invisible.
You struggle, you struggle.
Then, one day, things connect, everything suddenly seems obvious, and you move to the next level.
You repeat the process, you gain self-confidence, your relationships with others improve, your life gets better.
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