Arc Institute @arcinstitute
A new scientific institution for curiosity-driven biomedical science and technology. arcinstitute.org Palo Alto, CA Joined November 2021-
Tweets161
-
Followers22K
-
Following24
-
Likes90
Read our newest preprint to learn about orphan non-coding RNAs (oncRNAs) and how they form blood-readable digital molecular barcodes that capture the identity of cancer cells. A very long 🧵 biorxiv.org/content/10.110…
Excited to share the latest story from our group in @CellCellPress and so proud of the great science and incredible dedication of first authors @sculptorofdance and @CarolineScsGlia and all co authors (more details to follow) sciencedirect.com/science/articl…
Emerging technologies at the nexus of AI and health have the potential to augment our understanding of how to treat human diseases. We’re honored by the @BiswasFamilyFdn's gift, which will help support important computation-driven research. Thank you! bwnews.pr/49VImW8
More ML advances from @arcinstitute 🔥 @genophoria's lab reports in @CellGenomics a machine learning model that predicts RNA secretion. This will enable cool applications in noninvasive diagnostics and synthetic biology!
Excited to share our new preprint describing a highly scalable #CRISPR screening platform based on neuronal activity. biorxiv.org/content/10.110… Read more below from @scboggess04, who led this project:
Excited to share our new preprint describing a highly scalable #CRISPR screening platform based on neuronal activity. biorxiv.org/content/10.110… Read more below from @scboggess04, who led this project:
Check out our review on the regulatory pathways of translational control that are hijacked by cancer cells. The credit largely goes to @schen_sc and @a_navickas for putting this together over the holidays!
Check out our review on the regulatory pathways of translational control that are hijacked by cancer cells. The credit largely goes to @schen_sc and @a_navickas for putting this together over the holidays!
A new major collaborative project across the @BrianHie and Hsu labs, @arcinstitute and @StanfordEng - we’re excited for the future of foundation models in biology at Arc!
A new major collaborative project across the @BrianHie and Hsu labs, @arcinstitute and @StanfordEng - we’re excited for the future of foundation models in biology at Arc!
It was wonderful to work with Eric and the team on this project! It's incredible what an enthusiastic and diligent interdisciplinary team can accomplish together.
It was wonderful to work with Eric and the team on this project! It's incredible what an enthusiastic and diligent interdisciplinary team can accomplish together.
If you want to generate DNA in a browser, check out our @togethercompute playground/API: api.together.xyz/playground/gen… @huggingface checkpoints: huggingface.co/togethercomput… pip install: pypi.org/project/evo-mo… and more @arcinstitute tools at our Tools Hub: arcinstitute.org/tools
Is DNA all you need? Introducing Evo, a long context 7B foundation model for biology Evo has SOTA *zero-shot* prediction across DNA, RNA, and protein modalities Evo can generate DNA, RNA+proteins & make CRISPR-Cas systems for first time blog …n-model-tool-arc-institute.vercel.app/news/blog/evo
In some new work (the first from the new lab!), we lay out a vision for a biological foundation model that unites DNA, RNA, and protein modalities and operates at molecular, systems, and genome levels of scale. Blog: arcinstitute.org/news/blog/evo Preprint: arcinstitute.org/manuscripts/Evo
Is DNA all you need? In new work, we report Evo, a genomic foundation model that learns across the fundamental languages of biology: DNA, RNA, and proteins. Evo is capable of both prediction tasks and generative design, from molecular to whole genome scale.
.@sitaritapita and I are excited to share RESPLICE, a new RNA-programmable mode of editing that leverages RNA targeting CRISPR proteins and the endogenous spliceosomal machinery to enable versatile RNA edits in human cells! (1/12) biorxiv.org/content/10.110…
1 in 8 women in the US will receive a breast cancer diagnosis in their life. Arc Investigator @genophoria led a @TEDTalks session on applying advanced AI and novel RNA molecules to detect+track breast cancer – changing the future of how cancer is screened bit.ly/3HCZpzx
Just shared at @KeystoneSymp a new @arcinstitute discovery of the bridge RNA recombinase mechanism: a new class of natural RNA-guided systems that retains the key property of programmability from RNAi and CRISPR while enabling large-scale genome design beyond RNA and DNA cuts
☀️It’s a great week at Arc as we welcome our new Core Investigator @genophoria and his lab, and our first Science Fellow @zhou_jingtian! We’re proud to add these talented minds to our ranks, bringing with them a multidisciplinary approach to human disease research. Welcome, all!
RNAs have been historically very challenging to drug. @arcinstitute and @UCSF investigator Hani Goodarzi @genophoria reports an AI framework for targeting microRNAs with small molecules (with implications for breast cancer and RNA drivers of other diseases) Arc loves AI and RNA!
RNAs have been historically very challenging to drug. @arcinstitute and @UCSF investigator Hani Goodarzi @genophoria reports an AI framework for targeting microRNAs with small molecules (with implications for breast cancer and RNA drivers of other diseases) Arc loves AI and RNA! https://t.co/FOPjWlbpgu
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
Arjun Raj @arjunrajlab
25K Followers 2K Following Just another LLM. Tweets do not necessarily reflect the views of people in my lab or even my own views last week. https://t.co/fZAnUCqd12
Anshul Kundaje (anshu.. @anshulkundaje
22K Followers 2K Following Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU). Post: @anshulkundaje, Threads: anshulkundaje
Prachee Avasthi @PracheeAC
25K Followers 8K Following Co-founder & CSO @ArcadiaScience. Head of Open Science @AsteraInstitute. Immigrant. she/her
Niko McCarty 🧫 @NikoMcCarty
23K Followers 859 Following Writing and editing stories about scientific progress, especially in biology. Founding Editor @AsimovPress Head of Creative @AsimovBio
Fyodor Urnov @UrnovFyodor
15K Followers 532 Following Gene editor + Professor of Molecular Therapeutics @berkeleyMCB + Director of @igisci @danahercorp Beacon for CRISPR Cures.
Jason Shepherd @JasonSynaptic
14K Followers 3K Following 🇿🇦🇳🇿🇺🇸Neuroscientist @UUtah. Molecular mechanisms of memory, repurposed transposons, and virus-like intercellular signaling.
Dan Nomura @DanNomura
17K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology
James Olzmann @OlzmannLab
10K Followers 7K Following Associate Professor @UCBerkeley & Investigator @czbiohub. Lipid droplets, ferroptosis, ubiquitin, chembio, molecular therapeutics. Diversity, equity, inclusion.
Sergiu P. Pasca @Sergiu_P_Pasca
11K Followers 2K Following Kenneth T. Norris Prof of Psychiatry @Stanford; Uytengsu Director of @BrOrganogenesis; Physician-Scientist; Seeking to understand human brain assembly & disease
LukeGilbert @LukeGilbertSF
1K Followers 117 Following Core Investigator at Arc Institute and Associate Professor at UCSF
Michelle Monje🎗️ @michelle_monje
18K Followers 1K Following Neuroscientist. Neuro-oncologist. Mom. @Stanford @HHMInews @CancerNeurosci
Hani Goodarzi @genophoria
4K Followers 1K Following Core Investigator @arcinstitute | Associate Professor @Ucsf_Biochem @UCSFurology @UCSFCancer | {Computational, Cancer, RNA} biologist
Monther Abu-Remaileh @abu_remaileh
3K Followers 1K Following Palestinian Assistant Professor at Stanford University. My lab studies lysosomes and metabolism in health and disease.
Brunet Lab @BrunetLab
10K Followers 5K Following Aging lab @Stanford - Epigenomics and metabolism in #aging; Brain aging and rejuvenation; Neural stem cells; C. elegans; African #killifish
Omar Abudayyeh @omarabudayyeh
7K Followers 2K Following McGovern Fellow @mcgovernmit by way of @broadinstitute | @harvardmed |@MIT Molecular tool lab. Co-founder @Sherlock_bio & https://t.co/GnLoSlRvsZ & https://t.co/ElMMNGf8bL
Patrick Malone, MD Ph.. @patricksmalone
6K Followers 955 Following physician-scientist turned biotech investor @KdT_Ventures | helping founders build science and tech-driven companies | writing at https://t.co/w5M8DV8u92
Ethan Perlstein @eperlste
17K Followers 2K Following ceo @PerlaraPBC (@ycombinator W16), ceo @epalrestat, solo vc @AngelList, evo pharmacologist, mTOR worshipper, HODLer since '14, cofounder of Kai & Luca, bio/acc
Jacob Corn @jcornlab
5K Followers 508 Following Genome editing, functional genomics, and cells figuring out how to eat themselves without dying. Professor of Genome Biology at ETH Zürich.
Shriram Venkatesan @vshriram87
59 Followers 312 Following Biologist | Cricketer | Geek | Grammar-freak. Postdoc, @HalfmannLab, @ScienceStowers
GersonDeWinter @GersondeWinter
345 Followers 5K Following Biological Human Intelligence. Non Biological Intelligence (AGI) will replace allmost all jobs, thus ending the monetary economy and culture as we know it+NHI
Jing Wan @JingWan123
103 Followers 414 Following ENHPATHY, Regulatory element,3D Genome, Bioinformatics
Donald Areas (Prod by.. @bayareas23
48 Followers 129 Following
Dana Mahmood @deordered
8 Followers 649 Following Fine-tuning AI models oftentimes & practicing philosopher at other times.
Brian @bbalkus
893 Followers 333 Following
Elías Rashid Morales.. @elimoralsmendox
125 Followers 3K Following Estudiante de finanzas. Especializándome en procesos financieros con IA , data y BI. 📊📈 Entusiasta por el sector tecnológico y financiero.
Kesar Brown @KesarBrown
125 Followers 442 Following Helping AEs/SDRs focus on the human aspect of sales while @DearLeadApp takes care of the rest. Kesar Brown - a verb not a noun ™
Namrata Rastogi @doc_namrata
2K Followers 4K Following Healthcare Digital Transformation leader | Board Member | Investor | Advisor | Stanford GSB
osmosiposit @osmosiposit
11 Followers 347 Following
Osh 🐺🔊 @Osh_mahajan
6K Followers 6K Following Very fun, very nerdy. Love Fashion and technology .⌛️In search of growing markets and lost time .
Alejandro Sanders Vil.. @asandersv
1K Followers 6K Following Emprendedor, investigador & aprendedor (always) in training. Originally from Coyoacán 🇲🇽. {Social Sciences, Planetary Health, Philosophy, Policy, Design}
🔭 🍃 🦋 @regirock365
38 Followers 48 Following
Olivier @oli4jansen
161 Followers 2K Following
Shruthi S @ShruthiS1469997
0 Followers 5 Following
Roopkaran Singh @roopkaran14
0 Followers 195 Following
Aki Gurram @akigurram
21 Followers 176 Following hyphen lover: aspiring md-phd (physician-scientist-entrepreneur-investor-engineer)
『』 @lilbusdr1v3r
50 Followers 744 Following
Asad Murani e/acc @asad_murani
1K Followers 853 Following making the world a better place by sharing one meme at a time
Isabella Backman @IzzyBackman
547 Followers 362 Following Associate Editor and Writer @MagazineYale @YaleMed
Abhishek @plutodunk
288 Followers 3K Following Learning and building at @Collab_Land_. Member @developer_dao #6916
Maria Velez-Brochero @Mariavelezb
364 Followers 1K Following Ph.D student at @Rutgershealth | Former RA at @JohnsHopkins l BSc in Molecular Microbiology | 🦠
Sloop_de_Erevisiebela.. @Eredivisie_tax
165 Followers 891 Following Wij zijn klanten van Ziggo (en andere providers) die tegen het betalen voor eredivisievoetbal in ons abbonement zijn. Wij willen geen Fox Eredivisiebelasting!!!
Garima Aggarwal @GarimaA60302335
356 Followers 3K Following Doing decentralised AI since before it was cool | web3 software dev and content writer + I build dashboards for my day job 😍
Araf Sompod @ZihadiAl
2 Followers 82 Following Explorar Genetic Engineer Jashore University of Science and Technology
a @yuboaustin
66 Followers 444 Following
Nishant @bijani_nishant
227 Followers 2K Following CTO & CoFounder at @Codistepvtltd (Blockchain and AI development Studio). talks about Blockchain, AI, Metaverse and three.js , https://t.co/2jg9SGif9s
Nikita @nikitavoloboev
4K Followers 7K Following Make @LearnAnything_ Learn in public: https://t.co/GbFvuErkYn macOS course: https://t.co/JdbJWru6zG https://t.co/94R8ER7K2h https://t.co/ROkqhyhpEK
Tim | ONLYUP™ 💹 @MrOnlyUp
4K Followers 818 Following Engineering my life & pursuing truth. Currently building the ONLYUP™ brand💹💹
Requiem Network @requiemnet
7 Followers 11 Following Requiem Network provides a network of tailored solutions for businesses of all sizes and stages of development.
the.valere @the_valere
6K Followers 241 Following Mon contenu gratuit est mieux que les formations que t'achètes. Donc abonne toi !
Kwabena Yeboah @kwaby_10
591 Followers 746 Following
Patrick Cole @ColePatrickR
332 Followers 2K Following
CompoSecure @CompoSecure
2K Followers 3K Following CompoSecure, Inc. (Nasdaq: CMPO) is a leader in metal payment cards, security, and authentication solutions.
Anton Ermolov @TwanErms
99 Followers 314 Following Not all those who wander are lost. Passionate about all things travel, history, fitness, art, hiking, and technology. Investor @ GBV
DYOR @numatelly
36 Followers 174 Following computer engineer. I write Python for data analysis, ML and engineering. (I don’t like scraping). SQL is really a logic game. I love EXCEL
xaM srednoW @notmaxwonders
5 Followers 1K Following life is a strange place to be. ————•————•———•—————* the tortured few, the saved many. ————-•————-* 88, aBlood Oath.
Ayushi @ayushisachan97
312 Followers 2K Following Biostatistician @cdsa_faridabad @THSTIFaridabad @adapt_thsti @garbhinicohort||Alumnus @bhupro @lkouniv||Passionate about Bayesian stats, clinical trials & epi.
Sebastian Romero @tianfut
1K Followers 3K Following AI book author + bioinformatics+ animal rights activism
Heskel Balas 🚁 @heskelbalas
349 Followers 3K Following Dad, Engineer, Accountant, Founder. (latter 3 not necessarily in that order) Can I help? I'm not a VC, but my DMs are open
Stoicism Intake @ironmanvision
36 Followers 426 Following
Laura Kahn @LauraKahn1
2K Followers 2K Following Physician, Policy Researcher, Author, Columnist with @BulletinAtomic, Co-Founder @OneHealthNews, Educator @coursera. Promoting the One Health Concept.
Carlos Santamaría Ma.. @cjsanmar
19 Followers 902 Following 🪼🐡biology, 生物学家 | living stuff from paleothings to medicine🦠🐋
Ignacio Monje 💡 @ignaciomonje36
584 Followers 666 Following Entrepreneur | Founder | Digital Biz Advisor | Researcher in Entrepreneurship & Innovation 📚
$$$ — e/acc @sp1d3r_8eyes
60 Followers 333 Following
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
LukeGilbert @LukeGilbertSF
1K Followers 117 Following Core Investigator at Arc Institute and Associate Professor at UCSF
Hani Goodarzi @genophoria
4K Followers 1K Following Core Investigator @arcinstitute | Associate Professor @Ucsf_Biochem @UCSFurology @UCSFCancer | {Computational, Cancer, RNA} biologist
Marson Lab @MarsonLab
8K Followers 4K Following News from Dr. Alex Marson's lab @UCSF & @GladstoneInst, focusing on advances in immunology, CRISPR & genomics. Tweets represent personal views only.
Martin Kampmann @MartinUCSF
6K Followers 652 Following Associate Professor @UCSF. Molecular/cellular mechanisms of brain disease. Functional Genomics. Diversity & Inclusion. 🏳️🌈 he/him
Silvana Konermann @SKonermann
8K Followers 562 Following Cofounder @arcinstitute and Assistant Professor @Stanford. HHMI Hanna Gray Fellow. CRISPR, RNA and Alzheimer’s via @salkinstitute, Fast Grants and @MIT.
hazyresearch @HazyResearch
7K Followers 1K Following A research group in @StanfordAILab working on the foundations of machine learning & systems. https://t.co/JHK58TDorG Ostensibly supervised by Chris Ré
Jingyi Wei @JingyiWei4
379 Followers 292 Following Phd student at Stanford Bioengineering, Silvana Konermann lab @SKonermann, interested in genome editing and synthetic biology
Carolyn Bertozzi @CarolynBertozzi
77K Followers 3K Following Prof. @StanfordUChem; Baker Family Director, @Stanford_ChEMH; @HHMINews Investigator; EIC of @ACSCentSci; She/Her 🏳️🌈
Jingtian Zhou @zhou_jingtian
216 Followers 85 Following
Andrew C. Yang @andcyang
705 Followers 366 Following Assistant Professor @ UCSF & Gladstone. We study how the brain and body communicate in aging and neurodegeneration.
Robert Saxton @rsaxton_
961 Followers 650 Following Assistant Professor of Molecular and Cell Biology and Chemistry at UC Berkeley @berkeleyMCB @UCB_Chemistry
Alex Pollen @brainevodevo
869 Followers 791 Following
Michael Fischbach @mfgrp
6K Followers 707 Following Liu (Liao) Family Professor of Bioengineering, ChEM-H @Stanford.
Alanna Schepartz @AlannaSchepartz
4K Followers 2K Following Professor Chem/MCB, UC Berkeley. Director, Center for Genetically Encoded Materials (@cgem_cci). Editor-in-Chief @BiochemistryACS. Investigator, @czbiohub!
Anna Molofsky @AnnaMolofskyLab
4K Followers 277 Following brain development and neuropsychiatric disease. glia, neuroimmunity, and synapses @[email protected]
Isha Jain @ishahjain
2K Followers 445 Following Assistant Professor @Gladstone @UCSF studying the mysteries of oxygen, vitamins and aging
Jimmie Ye @yimmieg
3K Followers 171 Following Professor @ UCSF, Genomicist, Geneticist, Adopted Immunologist, #GirlDad, Immigrant
William J. Greenleaf @WJGreenleaf
10K Followers 124 Following Professor, Stanford University, Department of Genetics. Exploring the physical genome
Zhenan Bao @zhenanbao
3K Followers 0 Following
Faranak Fattahi @FaranakFattahi
1K Followers 548 Following
Brian Hie @BrianHie
5K Followers 402 Following Assistant professor @StanfordEng ChemE and @StanfordData, Innovation Investigator @arcinstitute | Machine learning for biology
Dr. April Pawluk @AprilPawluk
5K Followers 2K Following scientific publications @arcinstitute / scientific editing @LSE_editors. former Cell editor, Harvard microbiome center manager, & CRISPR scientist. she/her 🇨🇦
Read our newest preprint to learn about orphan non-coding RNAs (oncRNAs) and how they form blood-readable digital molecular barcodes that capture the identity of cancer cells. A very long 🧵 biorxiv.org/content/10.110…
Excited to share the latest story from our group in @CellCellPress and so proud of the great science and incredible dedication of first authors @sculptorofdance and @CarolineScsGlia and all co authors (more details to follow) sciencedirect.com/science/articl…
More ML advances from @arcinstitute 🔥 @genophoria's lab reports in @CellGenomics a machine learning model that predicts RNA secretion. This will enable cool applications in noninvasive diagnostics and synthetic biology!
Excited to share our new preprint describing a highly scalable #CRISPR screening platform based on neuronal activity. biorxiv.org/content/10.110… Read more below from @scboggess04, who led this project:
Have you ever wanted to profile how a molecular pathway affects neuronal activity, but didn't know where to start? I'm excited to share "A Massively Parallel CRISPR-Based Screening Platform for Modifiers of Neuronal Activity" 1/ biorxiv.org/content/10.110…
Check out our review on the regulatory pathways of translational control that are hijacked by cancer cells. The credit largely goes to @schen_sc and @a_navickas for putting this together over the holidays!
Thrilled to share our latest review on translational adaptation in breast cancer metastasis and the promising therapeutic opportunities it unveils! Immense thanks to @genophoria and @a_navickas !
Happy to join with 90 other colleagues in the biomolecular design community to support the responsible advancement of AI x biology
AI for biology has the potential to help solve some of the most important problems facing our society. Scientific openness will be critical for our field to progress. As scientists engaged in this work, with more than 90 signatories across the world, we are advancing a framework…
Evo: a foundation model for genomics! Using a well suited architecture, Evo learns from billions of bp of genomic sequence and performs well on several zero-shot prediction tasks on RNA, DNA and protein. Beautiful paper from @BrianHie & @pdhsu at @arcinstitute
I'm especially grateful to @arcinstitute for having the vision to support this kind of research!
A new major collaborative project across the @BrianHie and Hsu labs, @arcinstitute and @StanfordEng - we’re excited for the future of foundation models in biology at Arc!
A new major collaborative project across the @BrianHie and Hsu labs, @arcinstitute and @StanfordEng - we’re excited for the future of foundation models in biology at Arc!
Is DNA all you need? In new work, we report Evo, a genomic foundation model that learns across the fundamental languages of biology: DNA, RNA, and proteins. Evo is capable of both prediction tasks and generative design, from molecular to whole genome scale.
It was wonderful to work with Eric and the team on this project! It's incredible what an enthusiastic and diligent interdisciplinary team can accomplish together.
Is DNA all you need? Introducing Evo, a long context 7B foundation model for biology Evo has SOTA *zero-shot* prediction across DNA, RNA, and protein modalities Evo can generate DNA, RNA+proteins & make CRISPR-Cas systems for first time blog …n-model-tool-arc-institute.vercel.app/news/blog/evo
New from @arcinstitute:
Is DNA all you need? In new work, we report Evo, a genomic foundation model that learns across the fundamental languages of biology: DNA, RNA, and proteins. Evo is capable of both prediction tasks and generative design, from molecular to whole genome scale.
If you want to generate DNA in a browser, check out our @togethercompute playground/API: api.together.xyz/playground/gen… @huggingface checkpoints: huggingface.co/togethercomput… pip install: pypi.org/project/evo-mo… and more @arcinstitute tools at our Tools Hub: arcinstitute.org/tools
Introducing Evo: a long-context biological model based on StripedHyena that generalizes across DNA, RNA, and proteins. It is capable of prediction tasks and generative design, from molecular to whole genome scale (over 650k tokens in length). together.ai/blog/evo
web UI api.together.xyz/playground/gen… HF huggingface.co/togethercomput… Pip install (pypi.org/project/evo-mo…
This work was made possible with the entire Evo team, the most incredible researchers across @HazyResearch @arcinstitute @StanfordAILab @StanfordHAI @MichaelPoli6 @mgdurrant @ai_with_brains @realbriankang @StefanoErmon @pdhsu @BrianHie
We’ve made it super easy to try Evo with a web UI hosted on Together AI, with chat-like interface for generating so you can tune generation. huggingface.co/togethercomput…
Evo uses StripedHyena, a recent deep signal processing model with hyena + attn layers - 131k context, single nucleotide, byte level tokens - generates DNA @ 650k tokens long, 2500x longer than before paper arcinstitute.org/manuscripts/Evo code github.com/evo-design/evo
Evo is trained on 2.7M whole prokaryotic genomes & plasmids - 300B tokens from raw, unannotated genomic seqs - using next nucleotide/token prediction - to accelerate science, we curated & open source OpenGenome, the largest DNA pretraining dataset (in coming days)
Is DNA all you need? Introducing Evo, a long context 7B foundation model for biology Evo has SOTA *zero-shot* prediction across DNA, RNA, and protein modalities Evo can generate DNA, RNA+proteins & make CRISPR-Cas systems for first time blog …n-model-tool-arc-institute.vercel.app/news/blog/evo
In some new work (the first from the new lab!), we lay out a vision for a biological foundation model that unites DNA, RNA, and protein modalities and operates at molecular, systems, and genome levels of scale. Blog: arcinstitute.org/news/blog/evo Preprint: arcinstitute.org/manuscripts/Evo
Trends for United States
You might like
