Shantanu Pradhan @PradhanLab
Assistant Professor, Department of Biotechnology, IIT Madras Chennai, India Joined May 2019-
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Dept. of Biotechnology at IIT Madras is organizing a hands-on training workshop on Expansion Microscopy from July 20-23. Register soon for this exciting opportunity!
While India has its fair share of issues in science funding and management, the pursuit of basic (theoretical) science is not one of them. In its many publicly funded research and teaching institutions and universities, as faculty, we get full time salary across the year (unlike most US universities where you have to earn your summer salary from external grants). We have to teach, often perform some administrative duties, but we have complete freedom on pursuing our own research problem. In principle, therefore, India is a great place to do basic science if you do not need a lot of money and resources for it. The latter is the heart of the issue. Large-scale public funding for science is becoming more and more restricted to few areas which are thought to be of immediate relevance in terms of applications, or societal relevance. So if your basic science pursuit needs expensive instruments or computational facilities - you are compromised. This is where the real problem is. This is also why India has produced many outstanding theoreticians over time, but very few top class experimentalists and computational modelers in the modern era. While we will always desire that Government funding for science increases, careful consideration should also be given to balance the distribution of funds to maximise impact, given the existing talent pool. A mistake we have often repeated over decades, in my opinion, is following trends established elsewhere in a different country; allocating disproportionately high funding through various agencies to those few specific areas - without first creating the talent necessary to efficiently exploit that funding. On the one hand, this has allowed a lot of mediocrity to creep in and be funded without producing anything significant for the nation. On the other hand, the reduced allocation to general (open) science has compromised genuinely talented individuals - who already exist within the Indian scientific ecosystem, and could have scaled major grounds with additional support and put genuinely Indian innovation on the global map. It is great to see a private foundation support the creation of a new theoretical science institute in Mumbai this week. In India, this continues to be a rarity, with private philanthropic funding and industry involvement in science remaining below par. We hope to see more philanthropic pioneers enter this space and support high end instrumentation and computational centers that are the pillars of modern scientific developments. Concurrently, the central and state governments must work on enhancing and nurturing the scientific talent pool - the single most critical factor in the whole ecosystem is this human resource. There is, no alternative to this anywhere in the world over history. Governments have always been the scientists' closest ally. That bridge must not be broken.
#WATCH | Mumbai, Maharashtra: At an event hosted on 'Quantum Research', German Physicist and Nobel Laureate, Klaus von Klitzing says, "... I am fascinated to see that a basic research laboratory, privately funded, will be created here in India, like a Max Planck Institute. I am
Congratulations to Srashti Birla from Dept. of Biotechnology, IIT Madras for getting selected for the Bangalore Microscopy Course 2026! Wish her the best!
We conducted the Advanced Bioimaging Workshop 2026, May 18-20, in Dept. of Biotechnology, IIT Madras. Thank you to all the participants, speakers, trainers, sponsors and volunteers for making this a successful and educative event. @iitmbt
Dept. of Biotechnology, IIT Madras is organizing Workshop on Rheology and Soft Matter Mechanics in collaboration with Anton Paar. Register soon for this exciting hands-on-training opportunity!
MOSAIC: a versatile multimodal microscopy that seamlessly transitions between light-sheet, 2-photon, label-free and super-resolution modalities. @Eric_Betzig @ABCUCBerkeley @legant_lab nature.com/articles/s4159…
@ganitlabs Yes, because for many people, tone of the message is more important than the content of the message.
This is why "skin in the game" is such an important filter.
.@GadSaad agrees with Orwell: it takes an intellectual to come up with truly stupid ideas. When academics are disconnected from reality or accountability, bad ideas spread like parasites. While STEM professionals have to answer for their mistakes, humanities professors build
I got so, so much to say about this man. This is going to be long, so buckle up. There is a mental block in Indians that stems from the British rule. Someone who sits in a cabin, surrounded by papers and constantly looking busy has historically been associated with power, intelligence, and importance. During the colonial era, this perception made perfect sense. The people occupying those offices were not merely employees - they were extensions of the administrative machinery that governed the country. The clerk, the officer, the babu, the man behind the desk with stamps, files, and authority, represented access to power itself. Entire lives could be altered based on what happened inside those rooms. Naturally, generations grew up internalizing the idea that proximity to paperwork and administration equated to status. The British left decades ago, but cultural conditioning does not disappear with a flag change. The structure survives long after the rulers are gone. Even today, Indians subconsciously associate office environments with success and dignity in a way they rarely do with industrial or technical labor. A BPO employee wearing a formal shirt, sitting in an air-conditioned office and speaking English into a headset often commands more social respect than a CNC machinist capable of manufacturing components with tolerances tighter than a human hair. One is perceived as “corporate,” the other as “factory labor,” despite the latter possessing an extraordinarily specialized and economically valuable skillset. And that disconnect says something deeply uncomfortable about how we value work. A skilled machinist can take a raw block of metal and convert it into high-precision components that may end up in automobiles, aircraft, industrial robots, medical devices, or defense systems. That requires mathematical understanding, spatial reasoning, knowledge of materials, tooling strategy, machine behaviour, thermal expansion, tolerance stack-ups, feeds, speeds, vibration control, and process discipline. Mistakes are expensive. Precision is unforgiving. The work has tangible consequences in the real world. Yet socially, this individual is often viewed as somehow “below” someone doing process documentation for a foreign client in an outsourcing firm. India developed an economy where appearing professional became more important than producing something real. Entire generations were taught that escaping physical or industrial work was the ultimate marker of upward mobility. Parents wanted their children in offices because offices symbolized safety, cleanliness, English-speaking environments, and social elevation. Factories, workshops, shop floors, and machine environments became associated with struggle rather than expertise. The tragedy is that this mindset emerged precisely in a country that desperately needed strong manufacturing capability to become economically self-sufficient. You can see the consequences everywhere. We celebrate startup founders making apps that optimize food delivery by 3%, but rarely admire the people who understand tooling, fabrication, embedded systems, production engineering, process automation, or manufacturing reliability. We romanticize “corporate culture” while ignoring the fact that nations become powerful through industrial competence, not PowerPoint presentations. A society that cannot respect the people capable of building and maintaining physical systems eventually becomes dependent on those who can. The irony is almost absurd. The CNC machinist, the welder, the industrial technician, the maintenance engineer, the assembly line specialist - these are the people who convert engineering from theory into reality. Without them, designs remain drawings and simulations remain fantasies. They are the interface between ideas and existence itself. Yet because their expertise exists on a shop floor instead of inside a glass office cabin, society often treats them as lesser. And honestly, it makes me sick to witness.
India doesn't have a manufacturing problem. India has a respect problem. We respect the guy who cracked CAT more than the guy who can build an engine from scratch. And that concludes the whole story.
Very pleased that after a rigorous (and lengthy) review process, our paper visualizing how myosin generated forces modulate actin filament structure for mechanosensitive recogntion by α-catenin has appeared in @Nature nature.com/articles/s4158…
A new feature @ScienceMagazine on the clusters of cells that enhance the spread of cancer, and what can be done to break them up @ScienceVisuals science.org/content/articl…
Something small happened on my flight yesterday. IndiGo flight. Sitting next to a guy, well put together, well dressed. The kind of person you’d point to and say “educated, aware.” He finishes his snack. Looks at the trash in his hand. And places it on the floor under the seat in front. Not accidentally. Deliberately. The cabin crew came through for trash collection. Did their job perfectly. Collected from everyone’s hands, every tray table. The stuff on the floor, easy to miss from that angle, stayed. We landed. His cups and food box were still sitting there on the aircraft floor. And I just sat with this feeling I couldn’t quite name. It wasn’t anger. It was something closer to disappointment. Or maybe exhaustion. Because we’ve been having this conversation about civic sense in India for decades now. And nothing moves. Here’s what I’ve come to believe. It’s not an awareness problem. It’s not an education problem. It’s not even an income problem. It’s a “whose problem is it” problem. Most people in India have unconsciously decided that shared spaces, flights, roads, parks, footpaths, are not their responsibility. Someone is paid to clean it. Someone will handle it. Me? I’m just passing through. And that mindset is exactly where the problem begins. Because civic sense isn’t just about what you do. It’s about what you normalize. Every time someone litters and nobody reacts, the bar drops a little lower. Every time someone cleans up after themselves in a space nobody’s watching, the bar rises. We are all, quietly, setting the standard for each other. Choose the standard you want to live in.
Academics are not known for their EQ, but there are some scenarios where they put in all their effort to make it seem otherwise. 1) Responses to referee reports, which by decree, must be sufficiently obsequious, lest someone change their opinion for the worse. You cannot LLM your way out of this, the obsequiousness must come from your own heart. 2) Trying to gauge the emotional state of your dean (akin to an abusive relationship). Did we put in enough tit to receive that tat? Are we responding to all whims with sufficient joyful deference?
Every PI
Ernst Chladni was a German physicist and musician, often called "the father of acoustics." In the late 18th century, he developed a technique that made sound visible: he sprinkled sand on metal plates and bowed them with a violin bow. The sand migrated to the nodal lines revealing geometric patterns now known as Chladni figures. In 1808 when Napoleon saw the demonstration and was so impressed he offered a prize for the best mathematical explanation. Sophie Germain, a self-taught French mathematician was the only entrant who got the approach right - though her solution had some flaws. She became the first woman to win a prize from the Paris Academy of Sciences for her work on elasticity theory. The math describing Chladni figures later showed up in quantum mechanics when Schrödinger used similar mathematics to describe electron orbitals.
India isn’t dirty because people can’t clean, or lack civic sense. India is dirty because people genuinely believe it’s not their job. That belief comes from caste. And that belief is not accidental. It comes straight from caste conditioning drilled into people for generations. Caste in India was never just about hierarchy. It was about assigning work. And cleaning got pushed to the bottom. So now even today, people carry that same mindset without even realizing it. I am not the one who cleans. You go to a park, people will eat, throw garbage, walk away. Not because they’re unaware. Their brain literally doesn’t even register that they should pick it up. Why. Because somewhere deep inside, they think cleaning is a ‘lower’ person’s job. Same everywhere - Hill stations, rivers, tourist spots. Trash it and leave. Not laziness. Conditioning. Compare this with somewhere like Singapore - You eat at a place, people clean their own table. They carry tissues, wipe it, and throw garbage properly. Why? Because they don’t think it’s someone else’s job. Even Sri Lanka feels cleaner than India! And then we pretend it’s a Swachh Bharat problem. You can run a hundred Swachh Bharat campaigns. Put dustbins every ten steps. Nothing changes. Because the problem is not infrastructure. It’s identity.
| PNAS pnas.org/doi/10.1073/pn… The much-awaited publication from the lab is online now. Great teamwork led by @singhpallavi96 and the dendrite team in the lab. A new mechanism for dendrite regeneration, discovered using worm model at @DBT_NBRC @BricDbt @India_Alliance
Here is our updated database of grants for early careers researchers in all fields. It goes way beyond traditional NIH and NSF funding opportunities. We list 428 types of grants. Download it here: research.jhu.edu/rdt/funding-op…
Mohit Kumar Jolly @mkjolly15
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Nidhi @neuroxnidhi
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Arnav Saha @ArnavSaha19
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Bhavana Ravishankar @bhikbn381
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Lawrence Lau @LCMLau
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Shreya Kapoor @SKapoor_18
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Nicholas A. Peppas @NPeppas
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anu raghunathan @artanumus
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Signal Transduction a... @sigtrans_sttt
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Manas Guria,PhD @mguria17
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bioRxiv Biophysics @biorxiv_biophys
6K Followers 0 Following
Savani Anbalagan @SavaniAnbalagan
411 Followers 445 Following Creator of emerging field: Gasocrinology. Made it in Poland. | Follow for posts on academia. 🔬https://t.co/ao8gy8YNFj | 📰✨ https://t.co/sspd2DVfTb
American Society for ... @ASCBiology
35K Followers 1K Following Inclusive, international community of life scientists. Home to @MBoCjournal @CBELifescied.
J Cell Science @J_Cell_Sci
20K Followers 329 Following Journal of Cell Science publishes research and review-style articles that cover the complete range of topics in cell biology.
Saran Kumar @Saran__Kumar
123 Followers 736 Following A Human, a son,a father. Interested in spatial heterogeneity, vascular biology & tumor metabolism. Assistant Professor @ KSBS, IITD
Niranjan ツ @niranjanposts
265 Followers 1K Following film. music. tech. foodie. and aspiring editor. Always on the hunt for new experiences and creative outlets!
Sandhya Koushika @WormlockHolmes
6K Followers 810 Following Cellular neurobiologist @TIFRScience Mumbai, who loves genetics, live imaging and worms. Science is fun. "Let's go exploring". Sometimes writes poetry.
Tamal Das @tamal_das
1K Followers 318 Following Associate Professor at TIFR Hyderabad; Exploring the collective dynamics of cells in biology; Beyond Science: Family, Friends, and Football (🐐=Messi)
Sanjeev Sanyal @sanjeevsanyal
349K Followers 489 Following Writer,economist & sailor of ancient ships.This twitter handle belongs primarily to the writer, and only occasionally to the economist. RTs are not endorsements
Martin Picard @MitoPsychoBio
28K Followers 950 Following Mitochondrial Psychobiology. Bridging the science of energy and the human experience. Upcoming book: ENERGY (2027).
Jennifer Waters @JenCWaters
6K Followers 375 Following Microscopist builder. Director of @cite_at_hms, organizes/teaches @QIatCSHL course & the virtual microscopy education platform https://t.co/CdJnBdJS0M
Aravind @aravind
301K Followers 383 Following I talk about issues long before they happen. Now and then in touch with Turiya. I post conspiracies and nothing I say is real. Don't believe anything I post.
Kundan Sengupta @KundanSengupta
89 Followers 145 Following
Ishwariya Venkatesh @Ishwariya13
5K Followers 1K Following Senior scientist @ccmb_csir | Neurobiologist leading a team that’s unpacking the molecular basis of why some axons regenerate better than others |
IGNITE LIFE SCIENCE F... @ignitelsf
2K Followers 469 Following We are transforming how research is funded and executed, so that we can amplify the positive impact of science. To know more visit https://t.co/dbrJJ3ZoMH
Sounak Sahu @SounakSahu
1K Followers 1K Following Assistant Professor @nyulangone. Curious about organoids and breast cancer. PhD @UniofOxford. Postdoc @NIH #WeAreHiring #NewPI. All views are my own.
Prachi Garella @garellaprachi
8K Followers 639 Following Theoretical Physics PhD Candidate. Cohost @knowmadspodcast | My views are a function of time, but not a linear one. They’re more Bayesian.
Anushka Chowdhury @Anushka67480727
3 Followers 37 Following
Saravanan Palani @syncellbiolab
1K Followers 768 Following Asst Professor, EMBO Global Investigator, IA fellow @iiscbangalore Cell biology, Cytoskeleton, Synthetic biology, Evolution. Alumnus of @UniWarwick|DKFZ|MKU|VIT
Ullas Kolthur @UllasKolthur
4K Followers 612 Following Biologist, Director-CDFD. TIFR/TIFRH. Fellow IASc, INSA, NASI; EBM: JBC, FASEB, MCB. Science & Life enthusiast; Personal views; RTno endorse























