Advanced Bioimaging Center @ UC Berkeley @ABCUCBerkeley
A global collaborative center with groundbreaking imaging tools & technical expertise to tackle large scale imaging data projects UC Berkeley Joined July 2019-
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@Eric_Betzig @ABCUCBerkeley One microscope, every scale. MOSAIC images life from single molecules to whole organisms: dividing cells, remodeling organelles, regenerating zebrafish, Alzheimer's tissue at the nanoscale, live mouse neural dynamics. Credit: Fu, Liu, Milkie, Ruan et al., Nature Methods (2026).
Congrats to all 49 authors on the publication of our paper on the multimodal MOSAIC microscope, to be found here: nature.com/articles/s4159… A summary with movies I posted nearly a year ago can be found below.
1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too
MOSAIC: a versatile multimodal microscopy that seamlessly transitions between light-sheet, 2-photon, label-free and super-resolution modalities. @Eric_Betzig @ABCUCBerkeley @legant_lab nature.com/articles/s4159…
We are recruiting an instrumentation scientist! aprecruit.berkeley.edu/JPF05253
🔬🔦Check out our ‘Imaging spotlight’ on Volumetric Imaging via Photochemical Sectioning (VIPS) from @Ruixuan3, Srigokul Upadhyayula and colleagues. VIPS helps researchers scale super resolution imaging to large whole-mount tissues. focalplane.biologists.com/2025/12/02/ima…
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue. Learn more this week in Science: scim.ag/3LdbQqH
This work was made possible in part by support from @cziscience @czbiohub @SloanFoundation @BerkeleyLab @HHMINEWS @ThePhilomathia @NIH @NERSC
Read more here: science.org/doi/10.1126/sc… #ExM #LLSM #imaging #Neuroscience
Thrilled to share our Science cover! VIPS (volumetric imaging via photochemical sectioning) eliminates working-distance limits for whole-mount, nanoscale imaging. LLSM + photodegradable hydrogel + petabyte-scale compute → axons & myelin across mouse olfactory bulbs (WT vs NPC1).
Adaptive optical vision Fourier transformer (AOViFT): a machine learning framework for inferring image aberrations and restoring diffraction-limited performance. nature.com/articles/s4159…
1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too below. biorxiv.org/content/10.110…
Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. biorxiv.org/content/10.110… @Eric_Betzig @legant_lab
The MOSAIC reconfigurable microscope by @Eric_Betzig et al is finally out! MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics: biorxiv.org/content/10.110…
Unlocking the potential to image petabyte-scale datasets 😵💫! From #CZBiohubSF Investigator Gokul Upadhyayula and co-corresponding authors & @BerkeleyMCB colleagues Xiongtao Ruan and @Eric_Betzig.
Out today from Ruan, Betzig, Upadhyayula and colleagues! PetaKit5D offers versatile processing workflows for petabyte-scale light sheet microscopy data. nature.com/articles/s4159…
This work was led by Xiongtao Ruan and Matthew Mueller @ABCUCBerkeley @Eric_Betzig @berkeleyMCB @LBNLBioSci @LBNLresearch, and supported by @ThePhilomathia @czi @cziscience @HHMINEWS @HHMIJanelia @NERSC @SloanFoundation
PetaKit5D is a scalable and efficient software for processing large datasets from light sheet microscopy and other imaging modalities. It is available for use in MATLAB and Python, as well as a GUI that requires no coding. Try it and share your feedback! github.com/abcucberkeley/…
We are excited to introduce PetaKit5D, a comprehensive suite of software tools designed to tackle challenges in the handling of large datasets and make processing of petabyte-scale datasets feasible: nature.com/articles/s4159…
Almost everyone in microscopy (especially LSFM) talks about data deluge, but the tools haven't kept apace with the problems. Check out PetaKit5D for processing and analyzing your huge datasets!
Out today from Ruan, Betzig, Upadhyayula and colleagues! PetaKit5D offers versatile processing workflows for petabyte-scale light sheet microscopy data. nature.com/articles/s4159…
Out today from Ruan, Betzig, Upadhyayula and colleagues! PetaKit5D offers versatile processing workflows for petabyte-scale light sheet microscopy data. nature.com/articles/s4159…
Jean-Yves Tinevez @jytinevez
4K Followers 919 Following Image analysis, microscopy and software tools for Life Sciences. Facility engineer @ Institut Pasteur
Jen Lee @Lee_JenYi
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Robert Haase @haesleinhuepf
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DrLachie @DrLachie
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Andy Moore @aaandmoore
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Nikon Microscope Solu... @NikonInst
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3i @3i_inc
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biohub @biohub
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Martin Weigert (mawei... @martweig
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Loïc A. Royer 💻�... @loicaroyer
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Sam Connell @samuelconnell
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King Cada ᜃᜒᜅ�... @kingcada
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Mark Kittisopikul @markkitti
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Alex Carisey @alexcarisey
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Estibaliz Gómez de M... @gomez_mariscal
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Kyle Ferguson @KyleFergus21589
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Aashish Dhakal @dhakal99
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Cal Gnome @CalGnome
2K Followers 4K Following Left the garden for a bit to bring my magic to Cal football and have some fun with all things UC Berkeley.
Zhuoyu Zhang (Joey张... @zhuoyuzhang_bmo
63 Followers 592 Following I’m a student focus on biomedical optics and photonics research. Northeastern Univ. (BME. BS)→Chinese Academy of Science, SIAT→HUST(BME. PhD student)
michelle@stratocore @mich_stratocore
570 Followers 3K Following @Stratocore is the leading provider of Core Facility and Lab Management #SaaS software. #labmanagement #sharedresources #corefacilities #wecanhelp
Amine Driouchi @xyzDrch
155 Followers 489 Following Investigator at CxT Discovery. Previously at @EikonTX, @UChicago. @KingsCollegeLon and @UofT alum. 🔬👨🏻🔬🎾 🇲🇦🇫🇷🇬🇧🇨🇦🇺🇸
Yuechuan Lin @YuechuanLin
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Whoa @whoaboard
424 Followers 7K Following The whoa board makes things glow, it also makes glow-y things touch sensitive
Riccardo Tognato @RiccardoTognato
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DR. ANJU MEHRA @anjumehra633
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Fletcher Lab @FletcherLab_UCB
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John Kochalka @johnkochalka
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Jim Breyer @jimihendrixlive
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Onouterw @Onouterw655165
191 Followers 7K Following Be fearless in the pursuit of what sets your soul on fire.
Thermal @ThermalPR
754 Followers 5K Following The visionaries driving society’s greatest scientific and medical advances choose Thermal to communicate how they Impact Human Health™
Andrew Piskadlo @AndrewPiskadlo
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Martin Habif @MartinHabif
380 Followers 5K Following Scientifically speaking, Jack of all trades, master of none. Biased toward quantitative life sciences (he/him/his).
Ching-Lung Hsu @hiallen72
2K Followers 1K Following PI @ Academia Sinica. Neuron computation/integration, navigation, memory, dendrites, plasticity, ephys, modeling, hippocampus. NPAS @IBMS_AcadSinica @AcadSinica
Maximilian Hoffmann @hffmnn_m
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Yehuda M. Danino @DaninoYehuda
453 Followers 1K Following Post-doctoral fellow at Asya Rolls lab, TAU. Former Post-doc and PhD at WIS. Passionate about Cancer Neuroscience, RNA and molecular biology
buxiaodong @buxiaodong1987
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Jun-Liszt Li @poppingjun
1K Followers 2K Following 👨🔬Postdoc at @DMSabatini lab, @IOCBPrague, @IOCBBoston, PhD at @PKU1898, Tool dev🔑; Cell growth control (vascular, neuron), Signal transduction🧬⌬; 🎶/art.
Ewa Zarnowska 🦄 �... @ewadorotaz
2K Followers 4K Following Ph.D. | Ex-Neuro & Ephys | Lasers & Microscopes | Coherent Corp. | Opinions mine 🦋 https://t.co/pDpY4ySSCB
Shilpa Pothapragada @shilpap_
642 Followers 1K Following Something New @PopVaxIndia | 2023 @SchmidtFellows @wyssinstitute | PhD from @TIFRH_buzz | Women’s Health | Organ-on-chip | Mechanobiology |
Juan Manuel Perez Ber... @Juanmabertoldi1
364 Followers 908 Following Structural biologist Postdoctoral fellow in the Mahamid lab @ EMBL Heidelberg 🦠 Ph.D. in the Nogales lab @ UC Berkeley 🔬❄️
Chandel Angad @ChandelAngad
394 Followers 482 Following Studying how complex patterns form life @NorthwesternU |Developmental Systems Biology| Morphogenesis | RTK/ERK | Previously @iitdelhi | iGEM
Cesar VALADES-CRUZ @CessVala
171 Followers 484 Following BioImage Analyst in Wuhan • Associate Researcher at Institute of Hydrobiology, Chinese Academy of Sciences
David @Farmerbilly27
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MJ Allen @MJnanostretch
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fried brak @friedbr
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Vijay Iyer PhD @vijayiyer312
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Kevin Chen @kychen42
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Lu @Valarynicer
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Bahnisikha Barman, Ph... @bahnisikha_b
531 Followers 2K Following Research Instructor @AWeaverLab | Former postdoc | Cell-EV-RNA biology | Curious about cells, stories, and the art of living | Books • Cooking • Home decor
Tom Trainer @TomTrainerSci
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Zhenggang Zhu @ZhenggangZhu
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Chemistry at UIC @ChemistryatUIC
479 Followers 545 Following Advancing sustainability, health, and education through innovative chemistry research at Chicago's only public research institution.
Jennifer Waters @JenCWaters
6K Followers 375 Following Microscopist builder. Director of @cite_at_hms, organizes/teaches @QIatCSHL course & the virtual microscopy education platform https://t.co/CdJnBdJS0M
HHMI | Janelia @HHMIJanelia
28K Followers 478 Following A pioneering research center where scientists from many disciplines collaborate on science's most challenging problems. https://t.co/Jeu3KqBBI9
Bewersdorf Lab @bewersdorflab
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Andy Moore @aaandmoore
7K Followers 3K Following Cell biologist interested in organelles and how they move. Husband, dad, intermediate filament apologist, and postdoc in the @JLS_Lab at @HHMIJanelia.
biohub @biohub
29K Followers 601 Following Combining frontier AI & frontier biology to help scientists cure or prevent disease
Martin Weigert (mawei... @martweig
2K Followers 582 Following machine learning, image analysis, microscopy; Prof Comp Sci @tudresden_de & @Sca_DS.AI; Former EPFL, CSBD, MPI-CBG
Loïc A. Royer 💻�... @loicaroyer
6K Followers 2K Following Director @biohub SF #zfish #devbio #zebrahub #AI #Lightsheet #Imaging co-creator of @napari_imaging
Alex Rives @alexrives
12K Followers 875 Following AI for scientific discovery. Head of Science, Biohub. Founder and scientific director of the ESM project.
Yajie Liang @agetliang
329 Followers 417 Following Assistant Professor, University of Maryland School of Medicine
Amine Driouchi @xyzDrch
155 Followers 489 Following Investigator at CxT Discovery. Previously at @EikonTX, @UChicago. @KingsCollegeLon and @UofT alum. 🔬👨🏻🔬🎾 🇲🇦🇫🇷🇬🇧🇨🇦🇺🇸
Arena.ai @arena
164K Followers 214 Following Where AI meets the real world. Formerly LMArena. We measure and advance the frontier of AI through community-driven evaluation. We’re hiring → https://t.co/XBZCrseaWF
Kevin Terretaz @kWolbachia
715 Followers 431 Following Cells, microscopy, Wolbachia and ImageJ 🔬 https://t.co/2oRBxPr3ey
Ruixuan Gao @Ruixuan3
719 Followers 935 Following Assistant Professor of Chemistry and Biological Sciences @thisisUIC @ChemistryatUIC @UIC_BioS Studying Neurobiology, Chemistry, Microscopy, and Nanoelectronics
UC Berkeley MCB @berkeleyMCB
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Chemistry at UIC @ChemistryatUIC
479 Followers 545 Following Advancing sustainability, health, and education through innovative chemistry research at Chicago's only public research institution.
Stella Hurtley @SMHSci
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Chan Zuckerberg Biohu... @czbiohub
17K Followers 529 Following Please follow our official account to learn more about our work in frontier AI for biology
owl @owl_posting
15K Followers 919 Following cancer guy @noetik_ai || ex virus guy @dyno_tx || i write on bio ml at https://t.co/QPTHsR3fzm || podcast on https://t.co/JBM0K65IrO
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387 Followers 329 Following Science Officer Imaging Program @cziscience, neuroscientist, tech developer, science accelerator.
Eric Betzig @Eric_Betzig
3K Followers 24 Following An engineering physicist sometimes masquerading as a biologist or, on one occasion, a chemist. Aspiring astronaut. Nuclear is the way.
The New York Times @nytimes
53.5M Followers 846 Following News tips? Share them here: https://t.co/ghL9OoYKMM
Beata Science Art @beatascienceart
5K Followers 4K Following https://t.co/9XepCWAuvk I combine my ❤ for science & art to create #SciArt | IF/THEN Ambassador #WomenInSTEM | Molecular biologist | Creator of #Microscopya
David Hoffman @davephoffman
485 Followers 60 Following Sr. Staff Optical Engineer at @10xGenomics: 🔬+ 🧬. Views are my own (whose else’s would they be?)
Bin Yang @Bin_YANG_Optics
1K Followers 532 Following Optical engineer. Now @KLAcorp. Previously @czbiohub, @UCSF and @univbordeaux_EN. Experiences with light-sheet, super-resolution, wafer inspection, etc.Quantitative Imaging @QIatCSHL
3K Followers 76 Following Quantitative Imaging: From Acquisition to Analysis course at Cold Spring Harbor Laboratory / Tweets by @JenCWaters and @TalleyJLambert. Photo by Connie Brukin.
Foldscope @TeamFoldscope
6K Followers 1K Following We are the makers of Foldscope, the original paper microscope! Working to globally expand access to microscopy & the wonder of science.
Open MIC @ Berkeley @OpenMICBerkeley
1K Followers 732 Following A workgroup focused on light microscopy & quantitative imaging at @BerkeleyMIC. Tweets by @featherives.
Cyna Shirazinejad @CShirazinejad
223 Followers 1K Following
John Heddleston @JawnnyH
124 Followers 121 Following Unapologetic nerd and professional scientist. Particularly love lasers and microscopes.
Super Res Man @superresman
3K Followers 3K Following Covering all matters involving super resolution microscopy. Fascinated with all things single molecule.
Super Res Microscopy @SRMicro_papers
3K Followers 9 Following Twitterbot for anything related to super resolution microscopy
Optical Nanoscopy @OptNanoscopy
3K Followers 706 Following * Thoughts on #imaging, #microscopy and optical #nanoscopy / #superresolution microscopy! * Tweets by @Ulrike_Boehm - Enjoy!
Flamingo Project @microflamingo
591 Followers 192 Following Academic initiative building modular & shareable light sheet microscopes to unlock exciting new imaging experiments. Header by @JackiWhisenant & @madyroseart.
S Lewis @SamLewisPhD
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UC Berkeley @UCBerkeley
244K Followers 670 Following Official account of the University of California, Berkeley. Home of the @CalAthletics Golden Bears. 🐻 #BerkeleyNews #GoBears
OpenSPIM @openspim
2K Followers 365 Following News for the #lightsheet microscopy community. Including but not limited to the OpenSPIM project. Operated by Michael Weber, Morgridge Institute for Research.
Andrew York @AndrewGYork
6K Followers 3K Following I'm a physicist; I develop new microscopy techniques.
Talley Lambert @TalleyJLambert
3K Followers 484 Following Microscopist and Python enthusiast at Harvard Medical School. https://t.co/tsLZgvX0rR
















