OpenWorm @OpenWorm
OpenWorm is an open science project dedicated to creating the first digital organism, a C. elegans nematode. Get involved at http://t.co/N48aVJoGna openworm.org Joined December 2010-
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In 1986, John White published "The Mind of a Worm," the first complete wiring diagram of any animal's brain. 7,000+ synapses, mapped by hand. This year, he was awarded the @WileyGlobal Prize in Biomedical Sciences. He's donating his share to @OpenWorm.
This is the largest single donation in OpenWorm's history. We won't waste it. Full announcement + 2026 plans: openworm.tumblr.com/post/815435509…
We're organizing 2026 around: 29 Design Documents specifying how to model C. elegans, under scientific review A contributor progression model (Observer to Maintainer) AI-assisted contribution pathways The science is human-led. The scaling is AI-augmented.
Bravo @eboyden3 and @koerding ! thetransmitter.org/computational-…
Interested in doing post-doctoral work with OpenWorm? Check out this opportunity in the UK! ucl.ac.uk/work-at-ucl/se…
Now streaming: OpenWorm interview on the @DataSkeptic podcast open.spotify.com/episode/4ResE1…
Their preprint is online here: arxiv.org/abs/2208.04790 and you can explore the data set via an online browser here: funconn.princeton.edu and a basic simulator based on these data here: funsim.princeton.edu (3/4)
A major obstacle to modeling the nervous system of the worm has been the unknown weights of the connections. Which are excitatory or inhibitory and how strong? Well, the lab of @AndrewLeifer has put out a Neural Signal propagation atlas to address this critical gap (1/4)
OpenWorm retweeted
Fun to interactively play on the @OpenWorm site with our best mapped nervous system yet, and to think about building a virtual organism: opensourcebrain.org/projects/neuro…
Excited about the publication of our state-of-the-art 3D neuron atlas of #Celegans, the world's cutest worm. It's crazy how much smarts it gets from just 302 neurons! bmcbioinformatics.biomedcentral.com/articles/10.11…
Promising resource from the Flavell lab with freely moving whole-brain calcium imaging datasets: wormwideweb.org
OpenWorm retweeted
Omg @YeminiLab. The White Knight of neuron identification. As designated by Keynote Speaker Oliver Hobert. And well deserved moniker too. Go NeuroPAL! #Worm23
OpenWorm retweeted
How friendly is worm community? We converged on finding w Cohen and Emmons lab. Papers came out together (below). Started Glasgow #Worm23 w stimulating discussions over haggis pizza w Netta Cohen to discuss collaborations 1) nature.com/articles/s4158… 2) nature.com/articles/s4158…
OpenWorm retweeted
All winning entries of the #wormart at #Worm23 @GeneticsGSA. Wait until the end for a QR code for all entries. @foodskop started Art show in 1997. Do tag the winners/participants & RT. @chud8 @VarshaS53228024 @wormsense
OpenWorm retweeted
#Serotonin is a common but complex target of psychiatric drugs. A new study by the @MIT lab of Steven Flavell provides a deep but also brain-wide look at its role in producing behavior in C. elegans. picower.mit.edu/news/molecular… @ScienceMIT @MITbrainandcog #neuroscience
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