NewAmsterdam Pharma @NewAmsPharma
NewAmsterdam Pharma is a late-stage clinical biopharmaceutical company focused on developing transformative therapies for cardiometabolic diseases. newamsterdampharma.com Joined August 2021-
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A recent study in @ATHjournal notes that while we generally assume men have a more atherogenic lipid profile than women, that only holds true from ages 20 to 50. Before and after that, women typically have higher LDL-C and total cholesterol levels. bit.ly/3UlDYsT
Research from @TheFHFoundation found only 2% of U.S. patients at high risk of heart disease received a combination lipid-lowering therapy (LLT), and 80% of clinicians never prescribe combination LLTs. bit.ly/3Whf9Ru
The alarming rise in CVD deaths in recent years reinforces the importance of our work. Our R&D efforts are dedicated to combatting this trend by helping more patients reach and maintain their LDL-C goals. bit.ly/49UPoJz
Join us for a trip Back to the Future in this @Medscape CME that covers #CETP inhibition and how it may help reduce risk for patients with atherosclerotic cardiovascular disease (ASCVD). bit.ly/44hkudz
As a late-stage clinical biopharmaceutical company developing oral, non-statin medicines for people at risk of cardiovascular disease (CVD), our mission is to reverse the upward trend in CVD deaths. Meet the team taking on this formidable task. bit.ly/3WeDjMv
In this video, Christie Ballantyne, MD, discusses new data from the ROSE2 trial examining the potential synergistic effects of obicetrapib with ezetimibe in high-intensity statin users. hcplive.com/view/obicetrap… #Lipids
We’ve met the enrollment target in our pivotal Phase 3 PREVAIL CVOT and, driven by strong interest globally, expect to randomize more than 9,000 patients with a history of ASCVD. bit.ly/3TTqpAs
We're developing a selective CETP inhibitor, obicetrapib, observed in our ROSE2 study to cut LDL-C levels by a median 63.4% when taken with ezetimibe on top of high-intensity statins with or without food. Participants' muscle-related side effects were comparable to placebo.…
In our ROSE2 clinical trial, we observed significant decreases in both total (72.1%) and small (95.4%) LDL particle values among patients taking obicetrapib and ezetimibe on top of high-intensity statin therapy. This week at #ACC24, we’re presenting new data from the trial that…
A median 63.4% reduction in LDL-C was observed in patients receiving a combination of our potent CETP inhibitor, obicetrapib, and ezetimibe on top of high-intensity statins in our Phase 2 ROSE2 study. Our pivotal Phase 3 trial, TANDEM, will evaluate a fixed-dose combination of…
We're on our way to Atlanta for #ACC24, and we packed our data on the synergistic effect of obicetrapib and ezetimibe on circulating LDL particles. We look forward to collaborating with our peers on ways we can reduce the burden of cardiovascular disease. bit.ly/3U6TfPo
We’re excited to announce the appointment of Juliette Audet as our Chief Business Officer. While new to this management role, Juliette played a key role in the formation of NewAmsterdam Pharma and its early strategy as a member of our board of directors. bit.ly/4aFMXf4
According to NHANES data, high LDL-C is most prevalent among Mexican-American men and women, followed by Black men and women. We're developing a novel, oral, non-statin lipid-lowering therapy to help people reduce their LDL-C levels. bit.ly/3vb799p #MinorityHealth…
In multiple clinical trials, our novel, oral, non-statin lipid-lowering therapy, obicetrapib, has reduced LDL-C levels by 43-51% on top of high-intensity statins, with muscle-related pain side effects comparable to placebo, and no dietary restrictions or the need for dose…
While statins help many patients who need to reduce their risk of cardiovascular disease, they can also increase the risk of Type 2 #diabetes. In a comprehensive prespecified analysis, #CETP inhibition reduced diabetes risk genetically and clinically. bit.ly/3IASCqK…
We’ll be presenting a new analysis of data from our Phase 2 ROSE 2 clinical trial at #ACC24. The results demonstrate obicetrapib and ezetimibe’s impact on small dense LDL-C, a robust predictor of residual risk of future cardiovascular events. bit.ly/4ctcFoG
For now, there are no approved medicines to reduce Lp(a), but there are other ways to reduce your cardiovascular risk if you find you’re among the 1 in 5 people with high levels. @Drlipid shares several options to discuss with your doctor. #KnowLpa
We have multiple Phase 3 clinical trials underway to evaluate the efficacy of obicetrapib, our investigational non-statin lipid-lowering therapy. In two Phase 2 studies, we observed that obicetrapib reduced Lp(a) by 47-57% when taken with high-intensity statins. #KnowLpa
We have multiple Phase 3 clinical trials underway to evaluate the efficacy of obicetrapib, our investigational non-statin lipid-lowering therapy. In two Phase 2 studies, we observed that obicetrapib reduced Lp(a) by 47-57% when taken with high-intensity statins. #KnowLpa
Getting to #KnowLpa can help us reverse the alarming upward trend in deaths due to cardiovascular disease. Learn about this common genetic condition and find out if screening for Lp(a) is right for you.
Getting to #KnowLpa can help us reverse the alarming upward trend in deaths due to cardiovascular disease. Learn about this common genetic condition and find out if screening for Lp(a) is right for you.
High Lp(a) is a common genetic condition that causes early heart disease and stroke. As we join @TheFHFoundation in marking Lp(a) Awareness Day, get to #KnowLpa and understand what high levels can mean for your cardiovascular health. bit.ly/4a7gzlE
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29K Followers 3K Following Associate Professor #cardiologist #SoMe editor @CircOutcomes @JournalASEcho #BOD @ase360 @PittHealthSci @ColumbiaMed @NUFeinbergMed #echofirst #NewJersey girl👏👏👏 Congratulations to @mdavidsonmd, @JohnKastelein, and the entire @NewAmsPharma team. Very exciting! #LDL
We’ve met the enrollment target in our pivotal Phase 3 PREVAIL CVOT and, driven by strong interest globally, expect to randomize more than 9,000 patients with a history of ASCVD. bit.ly/3TTqpAs
In @NewAmsPharma's ROSE2 trial, we observed a median 63.4% reduction in LDL-C among participants taking a combination of our #CETP inhibitor, obicetrapib, and ezetimibe. Our Phase 3 TANDEM study will examine the two in a fixed-dose combination.
We are the Family Heart Foundation - a patient-centered #Research & #Advocacy organization dedicated to preventing early death and #HeartDisease by increasing the diagnosis, understanding and treatment of familial hypercholesterolemia and high lipoprotein(a). #KnowFH #KnowLpa
A4: Even though an estimated 1 in 5 have high Lp(a), fewer than 1% have ever had their Lp(a) tested. We have to do better! #KnowLpa
It's #LpaAwarenessDay! Let's raise our voices by sharing on social media or simply having a conversation. Together, we can save more families, more hearts. #KnowLpa Download from our toolkit & share today FamilyHeart.org/fh-awareness-d…
🚨Today is Lp(a) Awareness Day! Let's use our voices to shed light on the significance of Lp(a) testing. Early detection can be pivotal in preventing cardiovascular diseases. Join us in ensuring everyone knows why it's crucial to #KnowLpa @TheFHFoundation ow.ly/3CSf50R0ssI
I will be joining the prestigious faculty doing this one-hour Lp(a) Tweet-A-Thon - Will be introducing several new of my graphics - in rapid fire fashion @nationalipid @society_eas #KnowLpa @fhpatienteurope
Behind the scenes of our satellite media tour for Lp(a) Awareness! Thank you so much to @UTSWNews @dramitkhera and Family Heart Ambassador @purplevotaw for giving TV and radio interviews across the US to help everyone #KnowLpa! @KAWilemon
Do you know your Lp(a) level? In honor of Lp(a) Awareness Day on March 24, we are offering Lp(a) and LDL tests while supplies last! Get yours now: familyheart.org/ldl-and-lpa-sc…
sdLDL particles are more likely to get trapped in the arterial wall, leading to atherosclerosis. In @NewAmsPharma's ROSE2 clinical trial, patients receiving a combination of obicetrapib & ezetimibe achieved a >95% median reduction in small LDL-P levels. bit.ly/4coT5tt
All in Therapeutic Lipidology are holding their collective breaths. Obicetrapib is such a potentially exciting drug.
Our noteworthy progress and development in 2023 set us up to achieve significant milestones this year. By the end of Q1, we expect to have four active pivotal Phase 3 clinical trials, with two on track to report topline data in Q3 and Q4. Read more about our full-year 2023…
Translate 1 in 250 people who will have FH with >8 billion humans on the planet and recognize the true magnitude of the problem. @TheFHFoundation @nationallipid @society_eas @fhpatienteurope
Familial Hypercholesterolemia (FH) is a dominant genetic disorder, which means if you inherit the gene you will have the condition--even if you maintain a healthy diet and lifestyle. @American_Heart has information on the condition and current treatment options:
This was a #CME program I did for @PACEcme . #lipids #cvPrev. New therapies in the pipeline!
Dr. @ErinMichos shares The New Promise of CETPi, featuring an explanation of the mechanism, previous history, and the next generation of #CETP inhibitors--which starts with obicetrapib. Get up to speed in this 10-minute education segment from @PACEcme. bit.ly/4bpvgBs
A nice as well as succinct (short) review of the evolving CETP inhibition story, well done as usual, by @ErinMichos. Time for all to catch up and stay abreast of the topic. @nationallipid @society_eas
Dr. @ErinMichos shares The New Promise of CETPi, featuring an explanation of the mechanism, previous history, and the next generation of #CETP inhibitors--which starts with obicetrapib. Get up to speed in this 10-minute education segment from @PACEcme. bit.ly/4bpvgBs
@NewAmsPharma Promising. Excited for the upcoming clinical outcome studies
@NewAmsPharma Amazing and rapid as well as efficient journey by the team
@NewAmsPharma This is amazing news, really exited for obicetrapib’s phase 3