Helene M. Langevin, M.D. @NCCIH_Director
Official Twitter account of Helene M. Langevin, M.D., @NIH_NCCIH Director at the @NIH. Privacy: https://t.co/L0uvzovUlx nccih.nih.gov Bethesda, Maryland Joined January 2019-
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TOMORROW at 2 p.m. ET: @NIH_ODS and @NIH_NCCIH will hold a webinar for potential applicants for RFA-AT-24-008, Leveraging Data at Scale to Understand Natural Product Impacts on Whole Person Health (R01 Clinical Trial Not Allowed). Register: bit.ly/3vk6bYE
TOMORROW at 2 p.m. ET: @NIH_ODS and @NIH_NCCIH will hold a webinar for potential applicants for RFA-AT-24-008, Leveraging Data at Scale to Understand Natural Product Impacts on Whole Person Health (R01 Clinical Trial Not Allowed). Register: bit.ly/3vk6bYE
At one of our Hot Topics Webinars, three @NIH_NCCIH-funded early career investigators discussed their experiences doing research on health disparities—a high-priority area for our Center. Watch the video: bit.ly/43eK6H5 #MinorityHealthMonth
We will hold a technical assistance webinar on Tuesday, May 7, at 2 p.m. ET to discuss a unique funding opportunity: RFA-OD-24-014, “Botanical Dietary Supplements Translational Research Teams (RM1 Clinical Trial Required).” Register now. bit.ly/3vtQWMF
The three complementary approaches that showed the greatest increases between 2002 and 2022 were meditation, yoga, and massage therapy. The data also showed increased use of all three approaches to help manage pain. Read more: bit.ly/3SEfT0G
The three complementary approaches that showed the greatest increases between 2002 and 2022 were meditation, yoga, and massage therapy. The data also showed increased use of all three approaches to help manage pain. Read more: bit.ly/3SEfT0G
It’s important to tell your health care providers about all drugs and supplements you take so they can help you avoid harmful interactions. Learn more from this @NIH_NCCIH #KnowTheScience tool: bit.ly/3Z6EBs0
It’s important to tell your health care providers about all drugs and supplements you take so they can help you avoid harmful interactions. Learn more from this @NIH_NCCIH #KnowTheScience tool: bit.ly/3Z6EBs0
The @NIH_NCCIH Clinical Digest is our e-newsletter for health professionals. Each issue features evidence-based information on complementary health practices for a specific health condition. Read the latest issue and subscribe here: bit.ly/30PbqMw
The @NIH_NCCIH Clinical Digest is our e-newsletter for health professionals. Each issue features evidence-based information on complementary health practices for a specific health condition. Read the latest issue and subscribe here: bit.ly/30PbqMw
Research is just beginning to explain the roles of pressure-sensing neurons in sensations such as touch and pain. In this @NIH News in Health article, @NIH_NCCIH investigator @Alex_Chesler discusses new discoveries in this field. bit.ly/3vJ82pN
Multilevel interventions may be a uniquely effective way to address some complex health issues. This post on the @NIH_NCCIH research blog discusses ways to do research on multilevel interventions and provides links to useful resources. bit.ly/3VHDdwg
In a recent #DirectorsMessage, I discussed the importance of learning how to support the body’s natural healing abilities and promote the resolution of pain. Read more: bit.ly/3ITQNoH
Find out how the simplified framework for peer review of research project grant applications will affect existing and new @NIH funding opportunities. Register now for an @NIHgrants webinar to be held this Wednesday, April 17, at 1 p.m. ET. bit.ly/43IxKYc
National survey data show that the use of yoga by U.S. adults tripled between 2002 and 2022. See more survey data on complementary health approaches here: bit.ly/3UNuwjU
National survey data show that the use of yoga by U.S. adults tripled between 2002 and 2022. See more survey data on complementary health approaches here: bit.ly/3UNuwjU
We are ready for Day 2 at the 2024 International Congress on Integrative Medicine & Health!! Our #ChampionsofWholeHealth are ready to talk to you about funding opportunities and more. Find our booth and say hello 👋🏼 #IMCongress #IMCongress24
If you’re a clinician, you may also want to subscribe to our monthly Clinical Digest for Health Professionals. It provides evidence-based information on complementary health approaches and resources for your patients. bit.ly/30PbqMw
We hope our #IMCongress session on new strategies & methodologies for #WholePersonResearch sparked thoughts on the impact of taking a whole person health approach over the course of a lifetime. Thank you for joining the conversation!
We hope our #IMCongress session on new strategies & methodologies for #WholePersonResearch sparked thoughts on the impact of taking a whole person health approach over the course of a lifetime. Thank you for joining the conversation!
If you're attending #IMCongress24, join us on Thursday, 4/11 at 10 am for the session “New Strategies and Methodologies for Whole Person Research.” @NCCIH_Director will be presenting & NCCIH’s Dr. Emrin Horgusluoglu will be moderating. @imconsortium bit.ly/3xsQIGp
People with irritable bowel syndrome may find certain complementary health approaches—such as gut-directed hypnotherapy and peppermint oil—helpful in managing symptoms. Learn more from this @NIH_NCCIH fact sheet. #IBSAwarenessMonth bit.ly/3P3wM3p
You can’t always avoid stressful situations, so it helps to learn some techniques to reduce your stress levels and help you feel better. Check out our flyer “Press Reset on Stress” for ideas. #StressAwarenessMonth bit.ly/3gtBl8r
I recently had the pleasure of speaking about research on #WholePersonHealth—including the need to focus on maintaining and restoring health as well as treating disease—at the Academy of Integrative Health & Medicine. Watch the video: bit.ly/4ab7szZ
David Shurtleff @NCCIH_David
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11K Followers 1K Following Scientist & Psychologist • Professor • Director, Stanford Pain Relief Innovations Lab • Chief Science Advisor: AppliedVR • Advocate: Patient-centered pain careAlexander Chesler @Alex_Chesler
2K Followers 512 Following Scientist studying touch & pain. Opinions my own.National Library of M.. @NLM_NIH
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2K Followers 4K Following Assistant #Professor/#PI, Anesthesiology. Molecular & cellular physiology of #chronicpain. Tweets are my own. 🚵♂️🏃⛰️Dr. Rajesh Khanna of .. @KhannaLabUF
3K Followers 2K Following Prof. of Pharmacology & Therapeutics, Univ. of Florida COM | Director, Pain and Addiction Therapeutics (PATH) Collaboratory |🇮🇳🇴🇲🇨🇦🇺🇸Evidence Based Acupun.. @EBAcupuncture
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3K Followers 3K Following Official acct of the United States Association for the Study of Pain (USASP). Home to healthcare providers of all disciplines 🧠 Like/RT ≠endorse⚡️Greg Corder⚡�.. @FlyBottleEscape
4K Followers 2K Following Assistant Professor @Penn • Dept Psychiatry + Dept Neuroscience | Pain • Pleasure • PsychedelicsDr. Lauren Atlas @laurenatlas
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25 Followers 242 Following In the dull and boring world, there is also occasional luck. No cross, no crown.Rena “Liz” Courtn.. @drlizcourtney
16 Followers 78 Following Psychologist-Scientist • Outdoor Enthusiast• Program Director-PREVAIL Center of Chronic PainSarah Park @sarahjaepark
5 Followers 72 Following Postdoc Research Fellow @HarvardMed @BrighamWomens | MPH Student @HarvardChanSPH | Naturopathic Doctor | #Nutrition #IntegrativeHealth (she/her)Emiliana Pimentel @Emippimentel1
7 Followers 108 FollowingBerniceSidney @p7xj597DLSrfi
0 Followers 368 FollowingPain Steals Everythin.. @PainSteals
1K Followers 978 Following Disability Advocate, Medical Researcher Founder: CPASS - Chronic Pain Support Services Backup for @CanadaPain Meditation Student of Jeff Bien #PainKills #HOPEJenny_Chunli LU PhD @chunli_lu
14 Followers 255 Following Evidence based Chinese medicine, Systematic review, clinical trials, implementation science, knowledge translation, prediabetes, cancer care, tobacco controltoofaroutthere @2far_0utThere
0 Followers 223 Following Unremarkable NDV Dual Wielder S:11 D:14 C:14 I:15 W:12 C:8na zhang @nazhang_phd
608 Followers 516 Following Assistant Prof @UConnHDFS. @NIHMgov K01 PI. Alumni @ASU @UMNFSoS @Tsinghua_Uni. I study mindfulness, parent-focused intervention & developmental psychopathologyDan Wang @DanWang59674021
79 Followers 301 Following Postdoc @UVA neurosurgery @UVA school of medicine, PhD @uiowa @uiowaPTRS, pain scientist, human research, Neurophysiology, EEG, ECoG, QST, psychosocial measuresBioPharmaDiscoveries @BioPharmaDisc
19 Followers 41 FollowingAjay Manhapra @AjayManhapra
1K Followers 763 Following Specialist in recovering people with pain, NOT A PAIN SPECIALIST. People with pain have a lot more than pain and I’m interested in the other things!Lesous Consulting LLC @LesousCon
26 Followers 77 Following 🔬 Lesous Consulting - your premier destination for revolutionary educational and consulting services in clinical research and career advising.Libby Walunas @libbyluna
34 Followers 410 Following Yoga therapy, autism/neurodiversity, teaching, history, theatre, language, philosophy/consciousness, books, cats, scotch, karaokeAbolfazl Karimi @KarimiAbolfazl
146 Followers 3K FollowingSai Charan Paloju @SmartCherrysTho
27K Followers 17K Following Founder of Smart Cherrys Thoughts, Global Technology Influencer, International Speaker.Dr. David Norton DO @davidnorton99
349 Followers 1K Following Board Certified Neuromusculoskeletal Medicine Physician. (Nothing here is medical advice.)Kris Lok @krislok_hku
208 Followers 304 Following Assistant Professor | School of Nursing LKS Faculty of Medicine | The University of Hong Kong | Maternal & Child Health Researcher |IASP @IASPpain
22K Followers 2K Following The International Association for the Study of Pain is a multidisciplinary member-based professional community dedicated to improving pain relief worldwide.Wenhui (Vivian) Zhang @WenhuiVivian
70 Followers 499 Following Assistant Professor, Nursing, Data ScienceMediGraph @medigraphnet
22 Followers 254 Following MediGraph is a cutting-edge visualization tool designed for medical researchers, doctors, and stakeholders in the medical and healthcare industry.Qua @quawon1997
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498 Followers 528 Following Assistant Professor @hku_son @hkumed | Associate Director, Centre on Behavioral Health @HKUniversity | Gerontology & Behavioral Health Researcher |UCSD Sanford Institut.. @UCSDCompassion
950 Followers 2K Following Securing a kinder, more compassionate health system and world. Proud host of the Compassion in #MedicalEducation (C-MEd) Forum, July 8-9, 2024.Mitika K MD @KanabarMd
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542 Followers 882 Following Ex-stage actor, social worker, therapist in training interested in parallels between the history and practice of theatre and psychotherapy Fkn love books 📚LilMissPlantSlut @LilMsPlantSlut
130 Followers 2K Following Self Taught Botanist / Avid Gardener / Studying Plant Hybridization & Soil Science in my spare time / USDA Zone 5bSound Health Network @SoundHealthNet
862 Followers 473 Following The Sound Health Network is an initiative of the @neaarts, in partnership with the @ucsf, in collaboration with @nih, @kencen, and @reneefleming.Marufa Rupa @MarufaRupa93116
216 Followers 503 Following I am a digital marketing specialist. I will provide all kind of social media service and i will promote your profile organicallyMohamed Bala @Dr_MohamedBala
78 Followers 886 Following Community and preventive medicine physician @PHCCqatar Wellness and Lifestyle medicine are my core businessGerardo Amilivia @GerardoAmilivia
131 Followers 2K FollowingEnergyPoints @EnergyPointsApp
62 Followers 193 Following EnergyPoints is a mobile app designed to help those who suffer from Illness Related Fatigue (IRL) to self-administer acupressure to alleviate their symptoms.Journey_Joan @JoanJourne24550
31 Followers 1K FollowingJudith Graham @judith_graham
11K Followers 1K Following Health reporter interested in aging, health policy, medical news. Proud mom of two amazing people. RTs don't constitute endorsements.Caroline Thompson @CThompson_BME
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889 Followers 494 Following I am the Associate Director for Data Science at the National Institutes of Health. All views, likes, and retweets are my ownCorgigoals @Corgigoals
0 Followers 17 FollowingNana @NanaSaucedo1229
365 Followers 5K Following d kind. Interest: mental health, chronic pain treatment, , photography, reading learning. what's going on in the world.Bruno Solari @BrunoSolariM
567 Followers 1K Following Consultor de Mindfulness y autor de dos libros (hasta ahora)Tai @Lorecsky
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395 Followers 5K FollowingDavid Shurtleff @NCCIH_David
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11K Followers 1K Following Scientist & Psychologist • Professor • Director, Stanford Pain Relief Innovations Lab • Chief Science Advisor: AppliedVR • Advocate: Patient-centered pain careNational Library of M.. @NLM_NIH
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22K Followers 2K Following The International Association for the Study of Pain is a multidisciplinary member-based professional community dedicated to improving pain relief worldwide.Eric Green @NHGRI_Director
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1.1M Followers 187 Following 19th & 21st U.S. Surgeon General. Dad, husband, doctor, author. Dedicated to building a healthier, kinder, more connected world. https://t.co/GxSi2TxtADNIH NCCIH @NIH_NCCIH
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4K Followers 391 Following Home of the Purple Knights! ⚔️💜 #UBridgeport offers career-oriented undergraduate, graduate and professional degrees. Apply today! https://t.co/mjBkopgSL8Veterans Affairs @DeptVetAffairs
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12.3M Followers 2K Following We are the #UnitedNations’ health agency - #HealthForAll. ▶️ Always check our latest tweets on #COVID19 for updated advice/information.peter kilmarx @PeterKilmarx
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44K Followers 3K Following 29 February 2024 is Rare Disease Day. Raising awareness for patients, families and carers around the world that are affected by rare diseases. #RareDiseaseDayBeatrice Dupuy @Beatrice_Dupuy
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202K Followers 116 Following Official Twitter account for the Centers for Medicare & Medicaid Services (CMS). Official government account. Authentication: https://t.co/phdhdq21GgCrohn's & Colitis Fou.. @CrohnsColitisFn
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40K Followers 4K Following Our mission is to empower clinicians and researchers to improve digestive health. Also follow @AGA_Gastro @AGA_CGH @AGA_CMGH @AGA_TIGE @AGA_GHAdvances @AGA_GIHNNIH Radiology and Ima.. @NIHRadiology
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37K Followers 665 Following Presentador y director @cazadorcerebros @La2_TVE. Bioquímico. Domingos en @Avivir. Conferencias. Autor de S=EX2, El Ladrón de Cerebros y A Vivir la Ciencia.HPRC @HPRConline
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14K Followers 4K Following STEM Festival designed to inspire the next generation #Scifest #STEM #XSTEMAlex Danco @Alex_Danco
31K Followers 927 Following Making @Shopify wallet-aware. Other stuff at https://t.co/fZQ118K4XvLenny Bernstein @LennyMBernstein
9K Followers 3K Following Former health and medicine reporter for The Washington Post. Still freelancing on the same topics.Stephani Sutherland @SutherlandPhD
3K Followers 2K Following Neuroscientist, freelance journalist covering chronic pain, COVID @SciAm @newscientist; #scicomm for @a2cps_pain; teaching @pomonacollege; she/hersVitaly Napadow @VitalyNapadow
1K Followers 341 Following Director, Center for Pain Research, Spaulding Rehab Hospital & Center for Integrative Pain NeuroImaging (CIPNI), MGH; Professor, Harvard Med School. 🇺🇦NIH CFC @NIH_CFC
355 Followers 89 Following You Can Be the Face of Change for the causes you care about. Make a pledge through the NIH CFC. Privacy policy: https://t.co/xPZzwmPvys.…@NIH_NCCIH @ICIMH @imconsortium And what a day it's been so far!
@NCCIH_Director We're so looking forward to your talk and this session -- promises to be a fascinating discussion!
@NCCIH_Director I hope this thread heightens awareness of the role that Connective Tissue plays in inflammatory conditions, to promote deeper understanding of #EDS (and other CT disorders) multidimensional struggles, and to encourage investigations into this neglected area of research. /END
@NCCIH_Director With this being said, there are still many unknowns: What is the optimal mechanical force/duration for mitigating inflammation/scarring?; Do these rat studies extrapolate directly to humans?; To what extent does CT laxity in #EDS impair these anti-inflammatory response? 23/
@NCCIH_Director This impaired biomechanics affects inflammation as early as 48 hr and as late as 14 days - w/ likelihood for persistence beyond that since macrophages - an inflammatory cell responsible for chronic inflammation - were still increased at Day14 (at least for carrageenan model).
@NCCIH_Director To many w/ #EDS, it's as if they are in the "No Stretch" group a/w greater functional impairment (e.g., pain, gait issues), inflammation, and ? scarring. Furthermore, this is predominantly a direct consequence of CT mechanical forces, not "mental state" or muscle activity.
@NCCIH_Director So why spend so much time going through the details of these studies? How does this relate back to #EDS and #LongCOVID #MECFS? Since #EDS is primarily an issue of CT laxity, the mechanical tension needed to activate these ANTI-inflammatory effects may not be available. 20/
@NCCIH_Director Stretching significantly reduced the migration of neutrophils from the top of tissue to the solution below. And this was likely mediated by expression of Resolvin D1 from the tissue cells 19/
@NCCIH_Director Anesthesia simulated a drastic form of relaxation, while passive stretching eliminated active muscular component. Since both active and passive stretching reduced inflammatory size (no statistical difference b/w two), mechanical stretching was the likely active component.
@NCCIH_Director Furthermore, to eliminate factors of (1) mental relaxation and (2) muscle contraction, a slice of a rat's back was excised and placed on a buffer of chemoattractant (for neutrophils). She wanted to see whether stretching tissue would affect neutrophil migration into bath below.
@NCCIH_Director But what is active component of Stretching: Is it the state of relaxation (during "Yoga"), the mechanical stretching, or the active muscular contraction? @NCCIH_Director looked into this by randomizing rats to (1) anesthesia, (2) anesth + passive stretch, (3) active stretch.
@NCCIH_Director This data was showing that Stretching was not only just anti-inflammatory, but that (1) its effects can be seen as early as 2 days after injury and (2) it was mediated by BOTH increased anti-inflammatory and decreased pro-inflammatory factors. 15/
@NCCIH_Director INFLAMMATORY MEDIATORS: Further evaluation of the chemical factors (responsible for differences in inflammation) revealed that Stretching was a/w increased Resolvin D1 (anti-inflammatory) and decreased Leukotrine B4 (pro-inflammatory)! 14/
@NCCIH_Director INFLAMMATORY CELLS: There was also reduced inflammatory cells (in the lesion site) in Stretch group as determined by total cell count and neutrophil count. 13/
@NCCIH_Director INFLAMMATORY SIZE: Already at 48 hrs (in contrast to prior study = 14 days), Stretching was associated with reduced inflammatory size. 12/
@NCCIH_Director Much like previous study, carrageenan was injected in rat's back to simulate subacute inflammation. Rats also randomized to Stretch (2x/day, 10 mins at a time) vs. No Stretch groups. But this time, rats were euthanized at 48 hrs to assess acute response to stretching.
@NCCIH_Director The question was: how does this happen? What is the underlying mechanism and what is the active component? To assess this, Langevin did a f/u study looking at specific chemical signals: with a particular focus on pro-resolving (anti-inflammatory) mediators like Resolvins. 10/
@NCCIH_Director Somehow, stretching 10 mins at a time, for 2x/day, for 12 days (starting 2d after carrageenan injxn) leads to these remarkable reductions in pain/inflammation. And these stretches were not exorbitant - basically a posture that extended trunk by 20-30%. Much like doing yoga.
@NCCIH_Director INFLAMMATION: By histology and immunostaining (CD68), the amount of macrophages - the chronic inflammatory cells - were also significantly reduced in the Stretch group, but not nearly as low as those rats who only received Saline (non-inflammatory). 8/
@NCCIH_Director CONNECTIVE TISSUE THICKNESS: Using ultrasound images, she showed that Stretching significantly reduced the scarring induced by carrageenan-inflammation. 7/