Saltiel lab @LabSaltiel
Joined August 2020-
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really nice work. Glycogen plays an important regulatory role in many cells.
Neuronal glycogen powers anticipatory brain responses to food dlvr.it/TSlMGK
@LabSaltiel @UCSanDiego Behind the scenes with first author Churaibhon Wisessaowapak as she prepares Western Blot samples.
How does caloric restriction reduce energy expenditure while preserving energy storage? doi.org/10.1172/jci.in… Alan R. Saltiel @LabSaltiel & team @UCSanDiego show TBK1 acts as a brake on fat burning during fasting—and the combination of a TBK1 inhibitor and an AMPK activator reverses obesity and improves #MetabolicHealth in mice. The figure: Combined TBK1 inhibition and AMPK activation improve metabolic health in obese mice.
Tomorrow (5/12), join us for the 2026 Saltiel Life Sciences Symposium: Decoding #GLP1s. View the full schedule, including a poster session featuring U-M research: lsi.umich.edu/events/2026-05…
Join us May 12 for the 2026 Saltiel Life Sciences Syposium: Decoding GLP-1s! This full-day event will explore the fundamental cellular mechanisms behind the new generation of hashtag#GLP1 therapeutics, as well as ongoing efforts to improve them. Speakers include @AmberAlhadeff,
Dr. Irfan Lodhi and collaborators identified a pathway that regulates how the body breaks down fat during metabolic stress, including severe illness and cachexia, revealing insight into how stable fat stores are mobilized under stress conditions. bit.ly/3OVi7d7
@LabSpiegelman are you commenting on my high school yearbook picture?
UC San Diego Professor Elected to American Academy of Arts today.ucsd.edu/story/ucsan-di… As several of my friends have commented, standards seem to have slipped.
will be great to get back to Ann Arbor for this meeting.
Join us May 12 for the 2026 Saltiel Life Sciences Syposium: Decoding GLP-1s! This full-day event will explore the fundamental cellular mechanisms behind the new generation of hashtag#GLP1 therapeutics, as well as ongoing efforts to improve them. Speakers include @AmberAlhadeff,
Sad news. Such a sweet guy. Always positive and supportive, a serious scholar and terrific leader. He'll be missed.
A gentleman and scholar, leader in #islet biology, Editor of @Diabetes_ADA Professor Gordon Weir @Harvard @AmDiabetesAssn @JoslinDiabetes legacy.com/us/obituaries/… March 27 2026
With great sadness I report the passing of my scientific mentor Jesse Roth at age 91. Jesse was a brilliant & innovative scientist who led the field of membrane receptor biology from NIH diabetes branch. A small part of that family tree is shown. May his memory be a blessing.
Kvelling again about a former trainee. Xiao-wei Chen in another major breakthrough in Nature. Beautiful paper.
Nature research paper: CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis go.nature.com/4rzQTXg
Very proud of my former trainee Shannon Reilly @ShannonReilly5. An exciting new look at thermogenesis.
Fatty acids promote uncoupled respiration via ATP/ADP carriers in white adipocytes dlvr.it/TR6ggv
Meet the sixteen ASBMB members who were recognized for exceptional service and scientific impact across research, education, mentorship, outreach and leadership! asbmb.org/asbmb-today/pe… #ASBMBMemberNews #Biochemistry #MolecularBiology #ASBMBFellows
Meet the 2026 ASBMB Fellows Sixteen members were recognized for exceptional service and scientific impact across research, education, mentorship, outreach and leadership. Join us in celebrating them at #ASBMB26! ➡️ Learn more about the 2026 fellows: asbmb.org/asbmb-today/pe….
Today’s 📰#JEMjc @JExpMed highlights the work of @LabSaltiel @UCSDMedSchool @Nature reporting the role of neutrophil-derived IL-1β in preserving lipid stores during metabolic stress. nature.com/articles/s4158…
the next chapter in our investigation into how glycogen metabolism is regulated in fat cells; terrific work from Haipeng Fu and our collaborators.
Happy to share our paper is now published in @NatureComms. This work studies transcriptional regulation of glycogen metabolism genes in adipocytes. Grateful to my mentor @LabSaltiel and all collaborators for their guidance and support. nature.com/articles/s4146…
Happy to share our paper is now published in @NatureComms. This work studies transcriptional regulation of glycogen metabolism genes in adipocytes. Grateful to my mentor @LabSaltiel and all collaborators for their guidance and support. nature.com/articles/s4146…
@LabSpiegelman Thanks man, he was a prince. Miss him.
The longer version of my tribute to Pedro Cuatrecasas.
#NASmember Pedro Cuatrecasas devoted himself to improving human health, overseeing the development of 40+ new drugs across his career. Read about his work as a scientific innovator and leader in pharmaceutical discovery in a new memoir: ow.ly/A1vW50XAmEw #MemoirMonday
@LabSpiegelman Guess they were commemorating the discovery and development of MEK inhibitors with a picture from the same era. Wait- are you saying I've aged?
Three UC San Diego Professors Inducted Into the National Academy of Inventors for 2025 today.ucsd.edu/story/three-uc…
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