Joseph Halstead @Josephalstead
Lead Bioinformatician at All Wales Medical Genomics Service. Cardiff, England Joined May 2017-
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Poundbury, 2030 - You wake up - Lab-grown full English for breakfast, served by robot butler - Walk your children (which you can afford, because the housing crisis has been solved) to school - HS22 takes you direct to Spaceport Cornwall, which can sustain heavy-lift launches -…
Poundbury, 2030 - You wake up - Lab-grown full English for breakfast, served by robot butler - Walk your children (which you can afford, because the housing crisis has been solved) to school - HS22 takes you direct to Spaceport Cornwall, which can sustain heavy-lift launches -…
How to use NHS data for scientific research – without creating a privacy nightmare (FREE TO READ!) takes.jamesomalley.co.uk/p/how-to-use-n…
‘British Land research shows there is 10 times as much lab space in the US city of Boston as there is Oxford, Cambridge and London combined.’ telegraph.co.uk/politics/2024/…
All of these rights precede the ECHR. That’s not an argument against it but the standard of debate on this stuff is utterly ludicrous. In the U.K. the right to a fair trial can be traced back to 1215! Does anyone seriously think this wasn’t a right before 1998?! 🤭
All of these rights precede the ECHR. That’s not an argument against it but the standard of debate on this stuff is utterly ludicrous. In the U.K. the right to a fair trial can be traced back to 1215! Does anyone seriously think this wasn’t a right before 1998?! 🤭
Who had "The first class of drugs that works for weight loss is also the first class of drugs that stops neurodegeneration"?
I enjoyed the "many scientists can't communicate" clip. I don't think it's a big deal, but I worry about how normalised these types of judgements about technical people are. I know that it is so normalised in many of the fields it often happens in that they don't recognise it.
One year since GPT-4 release. Hope you all enjoyed some time to relax; it’ll have been the slowest 12 months of AI progress for quite some time to come.
real image of my man listening to me read “increased likelihood” and “variant detected” for like every health condition on my 23andme report
Guys me and my friends have this crazy bet where the first person to figure out a path around the city where you walk over each bridge once and only once gets a FREE BEER Please help me figure this one out guys if we can solve it that would be EPIC
This is going to sound hyperbolic, but it's not. I swear. You must watch this before you die or you have not experienced the full gamut of human artistic achievement. Where this video goes is NOT where it begins. youtu.be/VGhcSupkNs8?si…
update on the scottish no-pain FAAH story: i decided to check myself whether FAAH is associated with pain and found no signal. first, i ran associations in 430k sequenced british people in uk biobank on *all* 30k variants in and near FAAH, for 60 pain + mood phenotypes:
It's literally impossible to get a lifetime driving ban in this country. No matter how clear-cut it is, you can just full on run someone over deliberately and you'll be back on the road before they've even got used to their disability road.cc/content/news/v…
so the purported genetic basis of no-pain scottish lady is: 1) microdeletion downstream of gene FAAH 2) plus a common (25%) activity-reducing variant in FAAH ~1/12k europeans have this combo. this is common enough that if it caused no-pain syndrome we would likely know of it:
so the purported genetic basis of no-pain scottish lady is: 1) microdeletion downstream of gene FAAH 2) plus a common (25%) activity-reducing variant in FAAH ~1/12k europeans have this combo. this is common enough that if it caused no-pain syndrome we would likely know of it:
A new study published in the Archives of Disease in Childhood reports on the success of the WINGS service, the first NHS-funded rapid whole genome sequencing service for critically ill infants and children in UK. adc.bmj.com/content/early/…
Ten months ago, we launched the Vesuvius Challenge to solve the ancient problem of the Herculaneum Papyri, a library of scrolls that were flash-fried by the eruption of Mount Vesuvius in 79 AD. Today we are overjoyed to announce that our crazy project has succeeded. After 2000…
Thanks to my wonderful colleague @AllPlanets I knew where and when to look for a #meteor coming down over #Berlin tonight. Here's the video!
Definitely making progress! The #rmhautomatabuild is beginning its first full protocol today. @NorthThamesGLH @royalmarsdenNHS @automata_tech #genomics
AlphaGeometry is a system made up of 2️⃣ parts: 🔵 A neural language model, which can predict useful geometry constructions to solve problems 🔵 A symbolic deduction engine, which uses logical rules to deduce conclusions Both work together to find proofs for complex geometry…
@tomhfh Lizzie line for scale