Doris Kaltenecker @Dorie00
Postdoctoral researcher @HelmholtzMunich Enthusiastic about Metabolism & Cancer research | Transcriptional regulation | Tissue clearing l Light-sheet imaging Joined August 2010-
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Very excited that our cleared-mouse-brain analysis pipeline - DELiVR - is published now in @naturemethods! Paper: doi.org/10.1038/s41592… Code: github.com/erturklab/deli… Docker containers, test dataset, handbook: discotechnologies.org/DELiVR/
Today, we report that chronic intermittent fasting impairs β-cell maturation and function in adolescent mice. Using scRNA-seq of islets we define a β-cell maturation score, which was linked to T1D in humans. 👇 biorxiv.org/content/10.110…
Very excited to share that our DELiVR method is now open access published @naturemethods. We created a simple, brain-wide cell analysis deep learning tool, no coding needed! Fiji Plugin makes it accessible to all. nature.com/articles/s4159… by @Dorie00 @Rami96614090 @moritz_negwer
DELiVR, is a deep-learning pipeline for whole-brain cell mapping, which is trained on reference annotations generated in a virtual reality environment. nature.com/articles/s4159… #NBThighlight
For a quick summary, read the Research Briefing, here: nature.com/articles/s4159… @Dorie00
The DELiVR pipeline enables deep learning-based analysis of neuronal activity or other processes in the brain after tissue clearing and light-sheet imaging. DELiVR’s virtual reality approach facilitates the generation of training data for deep learning. nature.com/articles/s4159…
It is great to see this work online! Congrats again for the amazing work @Dorie00 @Rami96614090 @moritz_negwer @erturklab 👏🎉 a very useful tool to perform brain-wide neuronal activity analysis, showcased here in a cancer model. I love that colorful brain every time I see it😻
It is great to see this work online! Congrats again for the amazing work @Dorie00 @Rami96614090 @moritz_negwer @erturklab 👏🎉 a very useful tool to perform brain-wide neuronal activity analysis, showcased here in a cancer model. I love that colorful brain every time I see it😻
🧠Explore neuronal activity & cancer-induced weight loss and discover 🚀 DELiVR! Our user-friendly pipeline is out @naturemethods to simplify 3D imaging analysis, welcoming all researchers to dive into discovery.@erturklab 👏@Dorie00 @Rami96614090 @moritz_negwer
🧠Explore neuronal activity & cancer-induced weight loss and discover 🚀 DELiVR! Our user-friendly pipeline is out @naturemethods to simplify 3D imaging analysis, welcoming all researchers to dive into discovery.@erturklab 👏@Dorie00 @Rami96614090 @moritz_negwer
If you like what you see in the twittorial below, the best thing is that the magic is free and downloadable: github.com/erturklab/deli… discotechnologies.org/DELiVR
If you like what you see in the twittorial below, the best thing is that the magic is free and downloadable: github.com/erturklab/deli… discotechnologies.org/DELiVR
Excited to deliver you our DELiVR method! Congratulations 🥳🎉 team @erturklab
Excited to deliver you our DELiVR method! Congratulations 🥳🎉 team @erturklab
Very nice work from my colleagues, which is published in Nature Methods. Try this user-friendly Fiji Plugin for brain-wide cell analysis! Congrats @erturklab @Dorie00 @Rami96614090 @moritz_negwer
Very nice work from my colleagues, which is published in Nature Methods. Try this user-friendly Fiji Plugin for brain-wide cell analysis! Congrats @erturklab @Dorie00 @Rami96614090 @moritz_negwer
Our paper is now published at @naturemethods - very happy to work on this multidisciplinary project, check it out especially you are interested in #VirtualReality or #neuroscience 🧠!
Our paper is now published at @naturemethods - very happy to work on this multidisciplinary project, check it out especially you are interested in #VirtualReality or #neuroscience 🧠!
#3D Brain Analysis with #AI A team at #HelmholtzMunich & @LMU_Uniklinikum developed #DELiVR. The #DeepLearning tool allows #brain cell mapping without coding expertise. 🚀Fostering #PrecisionMedicine, e.g. for #Cancer-related weight loss. 👉t1p.de/smjnn
STAT3 activation in the liver drives muscle wasting and impaired ketogenesis in #cancercachexia. My first paper as a postdoc now published in @JCSM_cachexia with @GrossbergLab ➡️onlinelibrary.wiley.com/doi/10.1002/jc… @OHSUNews
Very excited to see our wildDISCO on the cover of Nature Biotechnology! It’s ranked 1st among the tracked articles of a similar age in Nature Biotechnology. @NatureBiotech
Very excited to see our wildDISCO on the cover of Nature Biotechnology! It’s ranked 1st among the tracked articles of a similar age in Nature Biotechnology. @NatureBiotech
Ali Max Erturk @erturklab
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Kılıç KD. et al. @kubilaydoki
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Institute of CVR @InstCardReg_FFM
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Trends in Pharmacolog.. @TrendsinPharma
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616 Followers 2K Following Spatial-Omics Team Lead | Clear-Omics | Tissue clearing | Light-sheet microscopy | Proteomics | Spatial Genomics | @HelmholtzMunich @UCLA alum | @network_alba
Helmholtz Munich | @H.. @HelmholtzMunich
9K Followers 2K Following German Research Center for Environmental Health We discover breakthrough solutions for better health in a changing world! https://t.co/DEY3BbGXvu
Helmholtz Diabetes Ce.. @helmholtz_diabc
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172 Followers 243 Following PhD, Research Group Leader at Helmholtz Diabetes Center IDC & Heidelberg University Hospital, Germany. https://t.co/hcOCTSvb2z
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515 Followers 862 Following Neuroscience fans. Associate professor in SUN YAT-SEN UNIVERSITY. Doctoral students advisor. Previous lab member in Helmholtz Munich center ITERM.
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Nature Metabolism @NatMetabolism
65K Followers 217 Following Nature Metabolism publishes studies that advance our understanding of metabolic and homeostatic processes in physiology and disease.
Leonardo Matta @LeonardoMatta
785 Followers 508 Following Exercise Physiology and Molecular Biology | Postdoctoral researcher at @Helmholtz_diabc | Associated researcher at @LMU_muenchen | @BarteltLab
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Andreas Bergthaler �.. @abergthaler
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Helmholtz Munich PhD .. @Health_talents
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1 Followers 2 Following
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453 Followers 2K Following Physiology professor at @Univcordoba | Neuroendocrinologist researcher in @PubMetTS lab at @IMIBIC | #Physiology #Neuroscience #Reproduction #Bioimaging
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Kılıç KD. et al. @kubilaydoki
133 Followers 815 Following Member of @UniversiteEge 🇹🇷PostdoctoralResearcher of @HelmholtzMunich 🇩🇪 GuestResearcher of @mfnberlin 🇩🇪
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23 Followers 102 Following
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151 Followers 573 Following Researcher Ph.D. student at @TU_Muenchen. A seeker and biologist who loves reading and learning. Interested in Space, AI, and Technology.
Julian Grünewald @grunewaju
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Rita Strack @rita_strack
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🧠🧬🔬🧫Saber.. @SaharkhizSaber
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22 Followers 52 Following Master student of Molecular Medicine at Ulm University, Germany
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Thierry Nordmann @NordmannThierry
113 Followers 182 Following Scientist, Dermatologist, Husband, Father of 3 ☀️
Vineet Augustine @vinnyaug1
958 Followers 1K Following Assistant Professor @UCSD Neurobiology | Prev: Faculty Fellow (PI) @scrippsresearch, PhD @caltech, CNS, BS-MS @iiserkol
Mohamad Amki @mohamad_elamki
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29 Followers 72 Following MSc in Molecular Biology-Biomedicine-UOC PhD in Molecular Endocrinology/Genomics-LMU currently Post-doc in Computational Biology, IDO, HMGU
Alexander Link @alinkmd
1K Followers 811 Following MD, Prof. Molecular Gastroenterology and Microbiota-associated Diseases; Department of Gastroenterology, Hepatology, Otto-von-Guericke University; EAGEN Board
Teresa Zimmers @TeresaZimmers
968 Followers 1K Following Flawed but hopeful human, scientist, mentor, and sometimes activist.
Institute of CVR @InstCardReg_FFM
944 Followers 444 Following The official Twitter of the Institute of Cardiovascular Regeneration.
Kristina Kuhbandner @KKuhbandner
86 Followers 79 Following Translational neuroscientist, passionate scientific writer and editor, @preLights author, loves nature
Jared Rosenblum @JaredRosenblum
454 Followers 2K Following Physician-scientist developing new technologies to unravel mysteries of the brain. Founder @neurosimplicity. Thoughts are my own.
Nelson Dusetti 🇫�.. @NelsonDusetti
2K Followers 4K Following Translational research in pancreatic cancer - @crcm_marseille - INSERM U1068
Elmina Mammadova-Bach @elmina_bach
371 Followers 650 Following Lab head, LMU Munich Cancer Clot and Inflammation 🇪🇺 🇫🇷 🇩🇪
Alvaro Crevenna @AlvaroCrevenna
2K Followers 3K Following Head of Microscopy @embl Rome. Helping the community to image their worlds. Opinions my own.
Marie Ploderer @marie_ploderer
40 Followers 76 Following PhD student in MPN research | Neubauer/Moriggllab @vetmedunivienna - big fan of megakaryocytes and platelets
Laure Bindels @Laure_Bindels
549 Followers 402 Following Interested in the gut microbiota-host crosstalk in cancer and associated cachexia. Assistant Professor at @UCLouvain. Editor at @MicrobiomeJ. Views are my own.
BraTS inpainting @BraTS_inpaint
269 Followers 859 Following ASNR-MICCAI BraTS 2023 challenge Synthesize healthy brain MRI scans from lesioned ones
Daniel Agudelo @DanielAgVal
158 Followers 368 Following Ph.D. researcher at @HelmholtzMunich @Uhlenhautlab. Football ⚽ lover. YNWA. My own thoughts 🇨🇴🇨🇴
Robert Haase @haesleinhuepf
11K Followers 4K Following Image Data Scientist, Lecturer, Training Coordinator @Sca_DS / @UniLeipzig, also @NFDI4BioImage, @NEUBIAS_, @GloBIAS_, GPUs, LLMs, AI, #openscience, views:mine
Amreen Mughal @AmrnMughal
454 Followers 871 Following New PI @nih_NINDS @nih_nhlbi @IRPatNIH. Stadtman Tenure-Track Investigator. Cerebral blood flow, Neuro+Vascular, Ion channels, Vascular Dementia.Exciting news 🥳! We are thrilled to announce that our consortium has been awarded the Cluster of Excellence #clusterofexcellence by the Austrian Science Fund #FWF to advance research in metabolic control of aging and disease (MetAGE) @UniGraz uni-graz.at/de/neuigkeiten…
Hello, Tweeps, Truly appreciate your support/views/likes/RTs all the way since I joined🐦4 yr ago I have lots of friends & intriguing chat/communications with fantastic people😆 However, since late last year, I've been experiencing a really struggling phase of my life (& lab as…
Nature research paper: 3D genomic mapping reveals multifocality of human pancreatic precancers go.nature.com/3QnldUH
Brain-muscle communication prevents muscle aging by maintaining daily physiology | Science. Super-interesting article by Pura Muñoz-Cánoves. science.org/doi/10.1126/sc…
Counting down - safe travels to #BioEng24 speakers, guests, presenters🙋🏼♂️👍🏻 To great science exchange, meeting good & making news friends in #bioengineering #biomedicalAI #biomedicine @ntziachristos @METorresPadilla @fabian_theis linkedin.com/posts/thomas-s…
Professor Rudolf Zechner was awarded the Jung-medal for medicine in recognition of his groundbreaking findings in lipid metabolism, bringing great honor to the Institute of Molecular Biosciences and #unigraz
Krankheiten des Stoffwechsels verstehen: Rudolf Zechner, Biochemiker #UniGraz, mit Jung-Medaille für Medizin in Gold ausgezeichnet uni-graz.at/de/neuigkeiten…
Congrats to @joedwardlewis on the fascinating model and findings in which DREADD-activated endogenous GIP secretion reduces food intake and body weight in DIO mice. sciencedirect.com/science/articl…
I am pleased to report that my septicemia has receded. Blood cultures are thus far negative, and I feel more energetic. For details, you can read the thread (but you don’t need to). The important bit is: the next genetic screens won’t need to be performed up in heaven.
Sarcopenic obesity is a growing clinical problem because of ageing populations and the increasing prevalence of obesity. A Review in @NatureRevEndo highlights the new consensus definition and diagnostic criteria for sarcopenic obesity. 🔒 go.nature.com/3QkT943
Normal or improved cardiovascular risk factors in IGF-I-deficient adults with growth hormone receptor deficiency #CVD #aging @MedCellPress cell.com/med/abstract/S…
I successfully defended my PhD!👩🎓🥳 I'm very grateful to my supervisor Dominik Paquet, my colleagues @PaquetLab and @ISD_Research and my thesis advisory committee @Haass_Lab @dieter_edbauer for their support. The past years were challenging and rewarding - a unique experience!
Today I have Successfully defended my PhD thesis, Officially Dr. now. I am thankful to My Supervisor, Prof Shiv K Sarin @drshivsarin, Co-Supervisiors @savykaur3 and other colleagues and Collaborators (Dr Csaba, Sweden) and Prof Ali for guidance and accurate protocols @erturklab
The peripheral circadian clock is regulated by the central clock in the suprachiasmatic nucleus (SCN) through responses to hormones, the neurological system, physical activity, and eating habits frontiersin.org/journals/endoc…
Yeni bilimsel çalışmamız Türk basımında @fesraoz
🧠BEYNİN İŞTAH BÖLGESİ KEŞFEDİLDİ @tv100 @erturklab
Extremely happy for my former colleague @sajjad_khani, @HandeTopel @DagmarWachten & @Kornfeld_JanW to see this work published @NatMetabolism now! A novel rheostat to brown fat function🔥 nature.com/articles/s4225…
#Circadian rhythm regulates function of #immune cells and participates in development of #tumors 👇 nature.com/articles/s4142…
@Dorie00 @thesugarscience @Rami96614090 @jocpae @erturklab Note that you will probably need to create your own custom (VR-annotated) training dataset for your image stacks. You will also need to turn off the ventricle masking in the advanced settings as follows:
@Dorie00 @thesugarscience @Rami96614090 @jocpae @erturklab To add to this: DELiVR can already spot cells in other organs in principle. If you have a light-sheet image stack and just want a cell count in csv format, you can disable the last three steps in the FIJI plugin:
Pretty awesome method democratising mouse brain mapping. (Max Perutz used to remind people that good methods are only becoming great if they become easy to use; this study is a great example of going this crucial extra mile) also, pure joy to dive deep into the data.
Absolutely thrilled to see our paper on a VR-trained deep learning pipeline for mapping mouse brain cells published in @naturemethods 🤩 Retrainable via Fiji for custom data, we used it to study brain activities in cancer.
Great new paper and resource!
Discover the story behind DELiVR, our VR-empowered deep learning pipeline! Our research briefing not only summarizes the paper, but also unveils the creative journey. Access it freely here: rdcu.be/dFw3g @Rami96614090 @moritz_negwer @jocpae @BerrielDiaz @erturklab
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