Jon Brestoff @BrestoffLab

Associate Professor MD/PhD @WashuMedicine studying #immunometabolism and #mitochondria transfer in metabolic diseases like #obesity #diabetes and #LeighSyndrome brestofflab.com St Louis, MO Joined July 2019

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Jon Brestoff @BrestoffLab

3 weeks ago

@CaicedoLab Wow! Congrats Andres!

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Mike Lustgarten, PhD @mike_lustgarten

a month ago

Butyrate extends health and lifespan in mice with mitochondrial deficiency nature.com/articles/s4146…

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Delgoffe Lab @DelgoffeLab

a month ago

Dearest gentle reader, we are delighted to announce a new story from our lab published in @Nature describing how a meal's systemic metabolic changes are interpreted by your immune system to enhance adaptive immunity. A thread 1/ nature.com/articles/s4158…

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Jon Brestoff @BrestoffLab

2 months ago

@v_moreno_juan @Samanthakrysa @Nature Great work! Congrats on your exciting and important paper!

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Jon Brestoff @BrestoffLab

2 months ago

Exciting new paper on #MitoCatch to target mitochondria transplants to cells of interest, rescuing neurons in #LHON Check out our News & Views in @Nature for a synopsis and big questions for the field: nature.com/articles/d4158… @washu_pathology @washumedicine @Samanthakrysa

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Jon Brestoff @BrestoffLab

2 months ago

@NatRevImmunol @rockygiwa

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Zane Koch @zanehkoch

2 months ago

ok actually insane paper published yesterday a research group in Korea built a gene switch you can control wirelessly using electromagnetic fields they exposed mice to 60 hz EMF (same frequency as your wall outlet) using a pair of large coils that generate a uniform magnetic field around the animal, for cyclic 3-day on / 4-day off pulses they showed this could: - activate OSK to do epigenetic reprogramming in progeroid and aged mice, extending lifespan and reversing aging markers across multiple tissues - conditionally switch on mutant amyloid genes only in aged mouse brains, letting them separate aging effects from amyloid effects to study AD biology in a way previous models couldn't no drugs, no impacts, just a magnetic field from outside the body

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Jon Brestoff @BrestoffLab

2 months ago

@v_moreno_juan @NicolasAvilaJA @Nature @IOB_ch Congrats! Exciting paper!

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Kika @v_moreno_juan

2 months ago

I am very happy to share that our paper is now published in @Nature 😊 Cell-type-targeted mitochondrial transplantation rescues cell degeneration. nature.com/articles/s4158… @IOB_ch (1/6)

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Nirosha J. Murugan @niroshajmurugan

2 months ago

Coming up in this research space, reviewers and peers made it very clear that any non-visual effects of light on biology were not to be discussed in the public forum. What an exciting development to see the effects of energetic patterns rooted within the electromagnetic spectrum featured in @Nature . Looking forward to the flood of exciting research programs and therapeutics to emerge in the next few years. The bittersweet reality is that the effects existed before this high-profile exposure. But better late than never!

Roger Seheult, MD @RogerSeheult

2 months ago

The is one of the most prestigious scientific journals in the world now acknowledging the benefits of long wavelength light (red or infrared light) therapy and the fact that we are indoors more now than ever before. For those that have had to endure scorn from fellow clinicians

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Jon Brestoff @BrestoffLab

5 months ago

@niroshajmurugan @TOEwithCurt I love this

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Martin Picard @MitoPsychoBio

5 months ago

I’m excited to be launching a new publication on Substack today: The Science and Experience of Energy! The last few years have invited me, like many of us, to clarify my place in the world. I’m a scientist who’s devoted his career to bridging mitochondrial science and psychobiology. But I want to do more than just publishing papers for other academics—it’s important, but not sufficient. I am moved to bridge science and experience not just in the lab, but in life as well. That’s why I’m writing the ENERGY book. And why starting this Substack makes sense now. It feels like a coming out of sort, from my academic shell: sharing some things that non-scientists may not know about, and sharing experiences that scientists typically don’t talk about. That bridging of science and experience, I feel, will propel us forward towards a deeper truth about who we are and how we can fulfill our potential. I’m excited to share this journey with you. In this publication, you’ll find three types of pieces: 1. The ENERGY SCIENCE pieces will share the latest advances in mitochondrial science. 2. The BEHIND THE PAPER category will describe how a specific study came to be, or the backstory of a discovery. 3. The LIVED EXPERIENCES will allow you to connect with other human beings willing to share their energetic experience of growth and transformation. Everything in this publication will always be free. I’ll put energy in each post. And as the publication grows, we’ll invite others to contribute their energy as well, including my wonderful wife @msahsorin. Please join us by subscribing. And if you feel so compelled, sharing with your community. martinpicard.substack.com