BowTiedBiotech 🧪🔬🧬 @BowTiedBiotech
Tri-Weekly Biotech Updates: Public & Private Market Updates, Company Building, Financing, Exit Strategies, and Emerging Science Trends | Current: Biotech VC linktr.ee/bowtiedbiotech United States Joined November 2021-
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CD19 T-cell Engagers in RA: potential to drive benefit across several autoimmune diseases characterized by autoreactive B cells. “…..the need for continuous infusion is a clear liability….” Source: William & Blair 🗣️BTBIOTECH: 5 days in hospital not ideal, maybe better than…
TOMORROW IS THE MOST IMPORTANT FOMC MEETING OF YOUR LIFE, SO READ THIS THREAD 🧵
Reading through $CABA materials for C19 CAR-T with upcoming readouts. Amazing these guys really went public off of academic data????
😎 Covalent Biologics - nice to see this one get done. Congrats to all involved.
Another day, another chapter in the HOW TO DESTROY AND INDUSTRY 101 BOOK The most hostile administration to biopharma innovation in my career…and it’s not even close. $XBI
Another day, another chapter in the HOW TO DESTROY AND INDUSTRY 101 BOOK The most hostile administration to biopharma innovation in my career…and it’s not even close. $XBI
By far the most exciting portfolio in pharma $LLY 😍 ✅ Obesity GLP ✅ Obesity beyond GLP ✅ RNAi ASCVD ✅ Heart failure, NASH/MASH, T2D ✅ Neuro / Pain ✅ pan-KRAS ✅ BCell depleters + strong C> + aggressive BD with an attitude to own certain spaces
By far the most exciting portfolio in pharma $LLY 😍 ✅ Obesity GLP ✅ Obesity beyond GLP ✅ RNAi ASCVD ✅ Heart failure, NASH/MASH, T2D ✅ Neuro / Pain ✅ pan-KRAS ✅ BCell depleters + strong C> + aggressive BD with an attitude to own certain spaces https://t.co/t8gNkWcb7P
This should not be shocking to anyone - the Philly FED forecast literally told you how the economic numbers would play out this year. In the end, they will print - it is inevitable. The program won’t be called QE, it will have some other camouflage around it, but the result…
This should not be shocking to anyone - the Philly FED forecast literally told you how the economic numbers would play out this year. In the end, they will print - it is inevitable. The program won’t be called QE, it will have some other camouflage around it, but the result…
🧠 NEUROPSYCH: Major Depressive Disorder (MDD) Landscape MADRS avg improvement over placebo: -2.8 @ohadhammer tu 4 sharing!
Supplemental table #1 to Sundays write up on fibrosis 👇🏼 See quoted post for full write up. @ohadhammer tu 4 sharing! 😉
Supplemental table #1 to Sundays write up on fibrosis 👇🏼 See quoted post for full write up. @ohadhammer tu 4 sharing! 😉 https://t.co/eF3x7GN5t6
Large Pharma Has $1 Trillion of M&A Firepower Based on Latest Financials "A big recent change is that $PFE has dropped off this page following its $SGEN deal." cc: $VKTX Source: Stifel
The first prime editing clinical trial has been cleared by @US_FDA to begin: prime editing of HSCs to treat chronic granulomatous disease (CGD). Congratulations to @PrimeMedicine on achieving this key milestone only 4.5 years after we published the first prime editing paper.
The first prime editing clinical trial has been cleared by @US_FDA to begin: prime editing of HSCs to treat chronic granulomatous disease (CGD). Congratulations to @PrimeMedicine on achieving this key milestone only 4.5 years after we published the first prime editing paper.
🚨 Russell 2000 Rebalancing - April 30th $XBI
$XFOR granted Rare Pediatric Disease Priority Review Voucher (PRV) concurrent with approval
$XFOR granted Rare Pediatric Disease Priority Review Voucher (PRV) concurrent with approval
😳$22B PYS VK2735 $VKTX
EPOCH 18: BIOTECH MARKET RESEARCH $BHVN 🚨ALERT: Phase I single ascending dose (SAD) data from BHV-1300 IgG degrader program 📅DATE: 5/31 R&D day 📈📉IMPLIED VOLATILITY: +/- 50% (l!nk to substa**ck in b!o)
Your future with Price Controls Inflation Reduction Act = Innovation Reduction Act
Epoch 17: Fibrosis- From Basics to Breakthroughs 👉 Massive area of unmet need 👉 Mega-blockbuster potential 👉 Approved product landscape 👉 Competitive intensity maps 👉 Whats it worth? Deal comps (M&A & license) (l!nk to substa**ck in b!o)
BIOTECH VS. PHARMA A biotech is a pharma company that’s “unencumbered” by revenue. That can mean more focus, greater speed, and more flexibility.. ..but it can also mean fewer resources, less institutional knowledge, and more risk. Our friends in biotech find awe in the…
LIVER FIBROSIS shown in this video is a common pathophysiology leading to cirrhosis 📬Check inbox tomorrow morning for our review of therapeutic development focused on diseases fibrosis including organ systems beyond liver (lung, kidney) 😲We will touch on: Approved Products,…
Andrew Pannu @andrewpannu
10K Followers 274 Following daily dose of biotech & healthcare commentary • founder • building software for the bioeconomy (we’re hiring software engineers!)Gator | Dentist @BowTiedGatorDDS
64K Followers 682 Following I’m the dentist that doesn’t agree with the other 9 | Not Medical Advice | Co-founder of Twitters favorite toothpaste @betterbiom 👇BowTiedOctopod | Culi.. @BowTiedOctopod
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3K Followers 1K Following AI Art •||• Coffee Cup Extraordinaire •||• Shop : https://t.co/YNoWZB7pr9 •||•inspired by @BowtiedBull °• Entertainment Purposes OnlyBertrand Delsuc @BertrandBio
16K Followers 253 Following Views=mine only, RT-like=/=endorse, no advice. 16y in Tech (chip design) & a bit of Bio :)BowTiedLoon | Degen I.. @BowTiedLoon
10K Followers 1K Following Don't take medical advice from cartoons on the internet. Inspired by @BowTiedBullBowTiedBrazil @bowtiedbrazil
6K Followers 772 Following Chad who escaped to Brazil. DM for tax optimization and strategy, offshoring, multinational taxation & corporate structuring https://t.co/OE7pB9vpllBruce Booth @LifeSciVC
50K Followers 731 Following Early stage biotech VC. Recovering scientist. Opinions expressed are solely my own and do not express the views or opinions of Atlas Venture.Yair Einhorn @yaireinhorn
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15K Followers 541 Following I return athletes to sport pain free. || Co-Founder of https://t.co/HS6l8K3R3fWei Zhao @zhaoweiasu
4K Followers 98 Following Interested in 🧬 Gene Editing: BE & PE || Science Enthusiast || Not Financial AdviceBowtied Jester @BowtiedJester
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10K Followers 379 Following Your source for the latest #Science and #Biotech news! If you're interested in #CRISPR #GeneEditing hit follow! Spaces podcast host🎙- all 20 episodes ⬇️BowTiedHalibut @bowtiedhalibut
3K Followers 1K Following Lifetime of Fishing Fresh & Salt | Healthcare Tech | Amazon FBA Biz | Inspired by @bowtiedbull and other toons. Let's go fishing.BowTiedCommoner | Hos.. @BowTiedCommoner
4K Followers 356 Following ~inspired by @BowTiedBull ~ check out my youtube channel!BowTiedTuna @BowTiedTuna
2K Followers 1K FollowingBowTiedQuoll | Surf @BowTiedQuoll
2K Followers 737 Following Sea shanties of a cartoon shitposting toward freedom. Pinned tweet = teaching you how to suck less at surfing.Bowtied Mastodon @BowTiedMastadon
2K Followers 483 Following Sum RE Guy | Equal parts Bluey’s Dad and Mr. Wilson | Homeschooling helps your child explore their super strength for 10.3k hours | Inspired by @bowtiedbullOnline Course HQ @onlinecoursehq
50 Followers 23 Following Helping you find the best educational content across the internet | Newsletter https://t.co/QqRxdWnWRHKurt S. Altrichter, C.. @kurtsaltrichter
19K Followers 2K Following Financial Advisor for Wealth Builders and Entrepreneurs | Founder of Ivory Hill | Pension Advisor | RiskSIGNAL™ | https://t.co/djSE20syjzGavin Crook 💙🏴�.. @GavinCrook3
435 Followers 2K Following Retired radiographer, and formerly warden on the Farne Islands. Lover of science and nature. Born at 315 ppm.Ruckus Patel @rockp0615
154 Followers 189 FollowingApxWrld @ApxxWorld
2 Followers 63 FollowingSB @megazoo
24 Followers 330 FollowingToytoat @toytoat7978
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11 Followers 110 FollowingJoannaHewlett @7Bv3NDWSGPR390
0 Followers 146 FollowingJm°♡• (Mim) 🤍 @JishaMone7887
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436 Followers 2K Following Citizen Science enthusiast. Currently in Author-Mode. A former Floridian.Slitare @slitare83666
0 Followers 173 FollowingJust_J 💁♂️�.. @JustJ_32
872 Followers 5K Following 🇨🇦🙄👁👁🌵🏳️🌈 BSc, OD, He/Him, Passion for environmental, evolutionary and climate science! ATHEIST!Konstantinos KAGIAS @kkagias
490 Followers 2K Following Research scientist, Synthetic Neurobiology Group, MIT. Science/Music/Chessgrant edwards @quest4certainty
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1K Followers 1K Following Sometimes science, nanotechnology, oncology, astrobiology, jokes, and laughs - @BlackInNanoTech - Silence Glaive SurpriseCorneliaVan @yLEZZmCDUKN31H
7 Followers 238 FollowingMAxK @profkorkmaz
386 Followers 2K Following Prof in Medicine AI in Science NYC, NY Sic Transit Gloria Mundi Memento Mori(Not Mark Zuckerberg) @papizuck
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1 Followers 167 FollowingYafees Sarwar @yafees
520 Followers 3K Following Head of Marketing @ CYTENA | Founder @ BiosciencingCosmasBio37 @CosmasBio37
13 Followers 26 Following Cardiologist, Love of Lipids, Clinical Trials, Random Musings.Modern Trials @ModernTrials
427 Followers 384 Following Modernizing clinical trials by leveraging EHR interoperability and automated tools to recruit qualified candidates, reducing time-to-market for new therapeuticsJust Published @JustPubbed
305 Followers 1K Following Michigan #scifi author #ISupportIndies - RTs are not endorsements - I follow #COVID #Science and #Politics in these very uncertain timesHallie Bieber (Kasper.. @HallieEBieber
84 Followers 462 Following Oncology Medical Science Liaison, Pediatric Oncology Nurse Practitioner.Federico @Pinolero1986
5K Followers 3K Following Pinolero 🇳🇮. Inmigrante. Latino. I tweet ⚽️, Sars2 , + equity for disenfranchised communities ✊. Science 🧬 + research🔬. Now sub 👨🏫. MS, Biomed. MKE. #vlasak @m1ghtyturtle
10 Followers 982 FollowingPharmaSource @ThePharmaSource
104 Followers 775 Following Pharma and Biotech procurement & outsourcing insights. Upcoming events: #CDMO LiveElliott Jacobs @ElliottJacobs7
22 Followers 953 FollowingSatyabrata Bandyopadh.. @satyatifrh
339 Followers 2K Following Researcher Working on Applications of AI/ML in Bio-molecular Simulation Passionate on Collective Variable Discovery Using Deep Learning TIFR Hyderabad, IndiaRobert @Robert66566669
0 Followers 149 Followingjoojoki @joojoki
4 Followers 17 FollowingJoseph Luciano @Joeyluciano45
62 Followers 144 Following Medical Sales Intern at Jigsaw Medical | Sophomore at ISU Pursuing Professional Sales | Stocks & Crypto | Pharma Industry InvestorElias Kass @DrDadSays
2K Followers 4K Following Pediatric primary care + infant feeding. Former engineer, now vaccine advocate & dad. Tweets are not medical advice. #ImmunizeUnder5s 🏳️🌈 he/himHumans 2.0 @IndianFriends
10K Followers 5K Following Higher intelligence from super natural resources & artificial intelligence through science, technology, healthcare, finance, management & divinity to enlighten!Roye Skornik @RoyeSkornik
333 Followers 6K Following Research into #Mechatronics #SpatialComputing #SimulationSoftware #Data #Aerospace #Biotech #Agtech #Nanotech #EnvironmentalEngineering #Physics #Design #AI.David @leicam9fan
188 Followers 2K Following socially distant since forever. lifetime photographer, full time stock trader, libtard. Jack of all trades, master of some.Brad Loncar @bradloncar
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23K Followers 761 Following Fan of #TechBio with #AI, #ML and #Automation, #CRISPR, #CellTech with #SynBio and #iPSC. I focus on #Genetics, #Immunology, #Hematology and #Oncology.BowTiedOx | Chad Body.. @BowTiedOx
70K Followers 997 Following Inspired by @BowTiedBull - The Strongest Cartoon In Crypto - Chad Scientists. - I will get you Bigger, Healthier, and Stronger. #BTC Not Medical Advice 💯Club💯Andrew Pannu @andrewpannu
10K Followers 274 Following daily dose of biotech & healthcare commentary • founder • building software for the bioeconomy (we’re hiring software engineers!)BowTiedSalesGuy @BowTiedSalesGuy
46K Followers 117 Following Inspired by @BowTiedBull. The most persuasive cartoon in Sales. Join my Free Newsletter: https://t.co/Zw440ETZWL DM for coaching/biz oppsBowTiedNightOwl @BowTiedNightOwl
28K Followers 769 Following Crypto. Finance. Memes @ https://t.co/jLsVR21zpU. | Team @bowtiedbullGator | Dentist @BowTiedGatorDDS
64K Followers 682 Following I’m the dentist that doesn’t agree with the other 9 | Not Medical Advice | Co-founder of Twitters favorite toothpaste @betterbiom 👇BowTiedOpossum | Ecom.. @BowTiedOpossum
21K Followers 129 Following Ecom & other digital stuff. Helping you get your first online business built https://t.co/p4Di4HhZYF Stay up to date👇David R. Liu @davidrliu
64K Followers 59 Following Professor at Harvard, Broad Institute, & HHMI. Our lab integrates chemistry & evolution to illuminate biology & enable new therapeutics. IG/Threads: @davidrliu1BowTiedOctopod | Culi.. @BowTiedOctopod
24K Followers 602 Following Inspired by @BowTiedBull | Cartoon Chef | Flavor Wizard | Latest Recipe: Making Great Pho at Home https://t.co/XZFh1c30MpFawn | Skincare Stacy @BowTiedFawn
19K Followers 434 Following Blending cosmetic chemistry & holistic health | Co-founder of @BetterBiomCoffee @BowTiedCoffee
3K Followers 1K Following AI Art •||• Coffee Cup Extraordinaire •||• Shop : https://t.co/YNoWZB7pr9 •||•inspired by @BowtiedBull °• Entertainment Purposes OnlyBertrand Delsuc @BertrandBio
16K Followers 253 Following Views=mine only, RT-like=/=endorse, no advice. 16y in Tech (chip design) & a bit of Bio :)BowtiedWhitebat + Rea.. @bowtiedwhitebat
4K Followers 350 Following Helping creators monetize with writing + marketing. Click here to make $1K/month to write tweets: https://t.co/5nUerHTIs5BowTiedLoon | Degen I.. @BowTiedLoon
10K Followers 1K Following Don't take medical advice from cartoons on the internet. Inspired by @BowTiedBullFarmer | Homesteadooo.. @bowtiedfarmer
10K Followers 990 Following Support small farmers. Fight back against corporate takeover. Learn how to eat like a king even when SHTF. Shop Farmer’s Market https://t.co/Y8iQM9lOz0 🍯BowTiedIguana @BowTiedIguana
22K Followers 279 Following Co-creator of the best *paid* DeFi research, launched June 2021 - 35,000 subscribers | Team @BowTiedBull | 👇 Our Tech/Finance/Trading projectsBowTiedApollo ☀️ .. @BowTiedApollo
6K Followers 349 Following World art and history posting. Graphic designer (https://t.co/J0WaeKOWzU) Digital/AI artist (https://t.co/XtqMxCc1SK) and writer.Kurt S. Altrichter, C.. @kurtsaltrichter
19K Followers 2K Following Financial Advisor for Wealth Builders and Entrepreneurs | Founder of Ivory Hill | Pension Advisor | RiskSIGNAL™ | https://t.co/djSE20syjzTara Samples, PhD, LC.. @tarasamples
616 Followers 2K Following FQHC Primary Care Psychologist, Momx4 (bio, foster2adopt) Exploring mental health, faith, parenting & the intersection of education, poverty, health, & justice.Martin Blanco @MartinMrMom
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2K Followers 1K Following Former campaign flack now in startups and private equityLeane Wells @WellsLeane
370 Followers 895 Following Science matters, #Injustice intolerant, “when you know better—do better!”, ethically grounded, love is love, news junky, graphic designer. mstdn: [email protected]Allie Greene, Ph.D. @allie_greene_
336 Followers 778 Following Medical Science Writer at EDTSI. #SciComm at https://t.co/JLz5NBlpdP. PhD @UCNeuroSci. @virginia_tech alum. Mental health advocate. Lover of cats & chocolate. She/herDancing cactus @Cactus_Dancer
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477 Followers 3K Following Sued the governor and now Running for Florida's Governor fighting corruption to save my children. #ImpeachHollyDerenthalJELOGO @JELOGO_CI
483 Followers 2K Following Entreprise de consulting et d'innovation technologique recherche et propose des solutions pour améliorer le fonctionnement de votre entreprise.Metron2112 @metron2112
187 Followers 558 Following Attention all planets of the Solar Federation. Stand by the Innovators. Freedom of expression and speech is paramount in a civilized society.Joni Pickett🧢 @JoniMPickett
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254 Followers 2K Following Radiation Oncologist, CLCC of Oran. CLCC of Sétif. UNICANCER François Baclesse Center.Peggy 🐦 @iPeggy
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2K Followers 5K Following Compassion not Hate. Science not Religion. “Two things are infinite: the universe and human stupidity; and I'm not sure about the universe.” A. EinsteinVal @val_shah
1K Followers 1K Following Owner of The Native Ad Agency - a native focused media buying Agency.AC @actrades01
245 Followers 353 Following Funded trader. My goal is $1.000.000 in Prop Firms Payouts. Follow my Journey. Current Verified Payouts: $14.606SerFiloLore @newSerFiloLore
487 Followers 4K FollowingJen (Diehl) Gallagher @WhtstheDiehlio
1K Followers 5K Following Communications & marketing | Views are my ownLIBERTAD Y ORDEN @Patriota1808
391 Followers 2K FollowingGavin Crook 💙🏴�.. @GavinCrook3
435 Followers 2K Following Retired radiographer, and formerly warden on the Farne Islands. Lover of science and nature. Born at 315 ppm.Sophia Theodossiou @sktheodossiou
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278 Followers 405 Following T-Shirts For Sale. Jesus Saves. SMTTT https://t.co/Z2lHw4hRQksmart medication eHea.. @SmartMedicati0n
110 Followers 388 Following Wir stehen seit 2010 für innovative Softwarelösungen und intelligente Vernetzung im Gesundheitswesen #eHealth #hämophilieOncology Awards @Oncology_Awards
947 Followers 5K Following Honoring excellence in oncology research. Follow us for updates on winners, events, and insights into the world of oncology.Jennifer @JenniferCusto13
542 Followers 1K Following Love science, nature, photography, archaeology, and spirituality. As a person thinketh, so in their heart are they🦋 🐞 🦂 🌏 🌞 🌛 🐯Fergus Cafferty 🌻 @FergusCafferty
450 Followers 306 Following Interventional and Diagnostic Radiologist tweeting about medicine, science, sport, random 'interesting' stuff.Mario Spaghetti @PastaPizzaMario
121 Followers 804 Followingzfjz @vvooppooxx
307 Followers 3K FollowingDan Wheelahan @Danwheels
709 Followers 2K Following Media Manager @Science_Academy. Previously @UNSW & @TheRACP. Nature lover, volunteer, gardener, foodie, father & husband. Views my own.Elena Conis @elenaconis
2K Followers 1K Following Historian of public health, medicine, envi & science journalism @UCBerkeley. Author, Vaccine Nation; Pink and Blue; How to Sell a Poison.Bkg2sci 📎 @mh_science3
75 Followers 34 Following Lover of science, nature, books, cats, music, gardening, Saint Cupcake, and 90.3% of the universe.𝑅𝑒𝓉𝒾𝓇�.. @Brhoe_Khena
411 Followers 567 Following Thoughts of a thriving man. Occasional Devil's advocate with a spice of Irreverent tweets here and there .Yeahboi @ZeroDark9000
83 Followers 278 FollowingRolex Ojuok @rolex_ojuok
690 Followers 4K FollowingDan Crowe @HoleDeal
906 Followers 904 Following Trying to figure out what I want to be when I get older.Emily Merchant @ashleystreet
1K Followers 2K Following Historian of science, technology, and medicine. Author of Building the Population Bomb (Oxford University Press, 2021).Jessica Leigh Hester @jessicahester
5K Followers 5K Following Science journalist + fledgling historian. PhD student @ihmjhu studying dissection and display. Wrote SEWER, writing about traces, trash, fossils @randomhouse!@BowTiedBiotech For those that don't know. Chicago PMI is a manufacturer index. Greater than 50 = great signal, growing Less than 50... Is viewed as negative and local economy is contracting
TOMORROW IS THE MOST IMPORTANT FOMC MEETING OF YOUR LIFE, SO READ THIS THREAD 🧵
@BowTiedBiotech $LLY pipeline Interesting balance ph1/ph2/ph3 almost 1/1/1 It should a pyramid like 3/2/1 They may strat buying early stage bios to fix the pipeline shape
Here is the cool covalent cross linking mAb platform. First patent is here. FSY seems to be the covalent linker target receptor. Super cool idea. patents.google.com/patent/WO20232…
Incubated by Avalon Ventures, 3 y.o. San Diego biotech Enlaza is heading toward the clinic with $161M in funding & a platform with which it could create the 1st covalent biologic drugs. @BioBonanos speaks with CEO Sergio Duron in @BioCentury
@BowTiedBiotech I see the plan is to let companies invest in R&D to develop things and then strip the patents whenever one of those things works.
First disease modifying and first RNAi editing drug now enrolling AATD participants and market is like MEH. $WVE
$WVE Wave Life Sciences Announces Approval of First Clinical Trial Application for RestorAATion-2 Trial o... - WVE • BioPharmCatalyst biopharmcatalyst.com/company/WVE/ne…
@BowTiedBiotech Listened to Sanofi call and they are open for acquisitions in 2-5B Eur range whether its early or late phase.
Hopefully we finally get good data for IO beyond Pd1s. IO in cold tumors is a huge unmet need.
@BowTiedBiotech Glaring omission in $MRK
@BowTiedBiotech I think $PFE $BMY $ABBV won’t go for larger size deals anytime soon as they did large sum of transactions. However, all the other big pharma still has a ton of cash.
The first prime editing clinical trial has been cleared by @US_FDA to begin: prime editing of HSCs to treat chronic granulomatous disease (CGD). Congratulations to @PrimeMedicine on achieving this key milestone only 4.5 years after we published the first prime editing paper.
We are pleased to announce that #FDA has cleared our IND application for PM359 for the treatment of chronic granulomatous disease (CGD), enabling Prime to initiate its Phase 1/2 clinical trial in the US. Details: investors.primemedicine.com/news-releases/… $PRME
$XFOR granted Rare Pediatric Disease Priority Review Voucher (PRV) concurrent with approval
$XFOR Announces FDA Approval of XOLREMDI (mavorixafor) Capsules, First Drug Indicated in Patients with WHIM Syndrome
The blatantly obvious answer - Japan price controls annihilate any successful drugs. If Democrats continue to think with no logic, same will be true in the US soon. trinitylifesciences.com/blog/japans-la…
BIOTECH VS. PHARMA A biotech is a pharma company that’s “unencumbered” by revenue. That can mean more focus, greater speed, and more flexibility.. ..but it can also mean fewer resources, less institutional knowledge, and more risk. Our friends in biotech find awe in the…
@BowTiedBiotech Fixin’ to drink some Wild Turkey now.