Abhishek Chatterjee @AChemSynBio
Scientist, Entrepreneur, Dad, Teacher, Mentor. Tweets are personal opinions. https://t.co/aabd7QsTfk sites.google.com/a/bc.edu/thech… Boston Joined November 2013-
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@Han_Xiao2016 @KevinKaichuang @xiongyih Congrats, Han!
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Abhishek Chatterjee retweeted
Co-Translational Incorporation of (R)- and (S)-β2-Hydroxyacids In Vivo: Directed Evolution of Efficient Aminoacyl-tRNA Synthetases | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…
An accompanying paper from @AlannaSchepartz and Jamie Cate groups shows how the E. coli ribosome supports the incorporation of the non-α-amino acid monomers pubs.acs.org/doi/10.1021/ja…
Chintan's @cpsoni_74 work demonstrating the efficient incorporation of non-α-amino acid backbones into proteins expressed in both E. coli and mammalian cells, just came out! A great collaborative effort from @cgem_cci! pubs.acs.org/doi/10.1021/ja…
Starting 2026 with Quan Pham's paper expanding the chemical toolbox for engineering AAV - New bioorthogonal labeling, including IEDDA, for efficient macromolecule attachment - Incorporation of two different chemistries for dual capsid labeling & much more: onlinelibrary.wiley.com/doi/full/10.10…
Excited to share our work with Eranthie Weerapana and Tim van Opijnen, co-led by @conor_loynd, @SinghaSoumya, and @SCanarelli! We introduce a new generation of BONCAT tools for versatile characterization of newly synthesized proteins in pathogenic bacteria rdcu.be/eI4M5
Abhishek Chatterjee retweeted
A facile chemical strategy to synthesize precise AAV-protein conjugates for targeted gene delivery dlvr.it/TMfgwR
Cool work from @Han_Xiao2016 on site-specific incorporation of an environment-sensitive fluorescent noncanonical amino acid to visualize protein microenvironment changes in living cells
Genetically incorporating environment-sensitive noncanonical amino acids containing rotor-based fluorophores to target proteins enables real-time visualization of microenvironment changes in protein substructures nature.com/articles/s4158…
@Linlab_ZJU Congrats, Shixian!
Our work @cgem_cci on co-translational incorporation of a noncanonical monomer into a protein, followed by its triggered post-translational chemical rearrangement, yielding novel backbone modifications. nature.com/articles/s4158…
Abhishek Chatterjee retweeted
Happy to see this new T7 replicon based orthogonal replication system in E. coli. Congrats to the Diercks and Schultz lab teams at Scripps Research! science.org/doi/10.1126/sc…
@fried_lab @JohnsHopkins Congratulations!
Abhishek Chatterjee retweeted
I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with @WalterIsaacson & @amanpour on @amanpourCoPBS, airing on @PBS tonight at 11 pm ET, and on @cnni earlier today. Pls share! youtube.com/watch?v=8YhJM6…
Abhishek Chatterjee retweeted
Today in @ScienceMagazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with @SternbergLab. 1/13 drive.google.com/file/d/1I-UbCR…
Abhishek Chatterjee retweeted
Writing in @J_A_C_S, we report a sugar-derived single-addition monomer that can be added together with other monomers in #ROMP and install functional groups at the chain end of metathesis polymers. #glycotime #polymer #NSFfunded pubs.acs.org/doi/10.1021/ja…
@ozalabCP @StanfordChild Wishing her a speedy recovery!
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