Stephan Hacker (inactive account) @StephanHacker2
Inactive account. Find me at: @stephanhacker2.bsky.social @[email protected] https://t.co/kPr9QkAN2S universiteitleiden.nl/en/staffmember… Leiden, The Netherlands Joined July 2018-
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Interesting paper by the groups of Jean-Marie Lehn and Oleksandr Koniev in @J_A_C_S. They developed 6-fluorosalicylaldehydes into tools that initially form imines with lysines. This activates them for irreversible modification of cysteines via SNAr. pubs.acs.org/doi/10.1021/ja…
Apparently the same for a lot of German universities leaving. #WissXit tagesschau.de/inland/hochsch… (Article in German)
Very interesting development that the Dutch research funding organization @NWONieuws is quitting twitter. It might be time to consider doing the same. I hope to find them back at one of the other platforms in addition to LinkedIn. nwo.nl/en/news/nwo-st…
Very interesting development that the Dutch research funding organization @NWONieuws is quitting twitter. It might be time to consider doing the same. I hope to find them back at one of the other platforms in addition to LinkedIn. nwo.nl/en/news/nwo-st…
If you are looking for exciting scientific content (with a focus on #ChemBio, #Chemistry, #ABPP, #ChemicalProteomics) over on the other platform, check out these starter packs: short list: go.bsky.app/C4URhFa pack 1: go.bsky.app/3SyoVNw pack 2: go.bsky.app/9keb2TP
Very interesting paper by the groups of @CossarPeter and Luc Brunsveld in @ChemicalScience. An exciting chemical crosslinker that reacts with a cysteine and a histidine to identify interactions of 14-3-3 with intrinsically disordered proteins. pubs.rsc.org/en/Content/Art…
Very excited to see what is coming for DIA-NN 2.0.
DIA-NN 2.0 release is almost ready, will come with some big news. One is scanning methods support, at the moment doing some tuning of the algorithm using Synchro-PASEF data by @labs_mann :) Turns out, 'Q1 information' is really helpful for gaining peptidoform confidence. Likely
DIA-NN 2.0 release is almost ready, will come with some big news. One is scanning methods support, at the moment doing some tuning of the algorithm using Synchro-PASEF data by @labs_mann :) Turns out, 'Q1 information' is really helpful for gaining peptidoform confidence. Likely also channel-confidence in plexDIA.
If you are interested in 𝗔𝗰𝘁𝗶𝘃𝗶𝘁𝘆-𝗕𝗮𝘀𝗲𝗱 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗣𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴, definitely consider the #ABPP2025 conference @abpp2025london on March 30th to April 2nd, 2025, at The Francis Crick Institute. Registration deadlines have been updated. linkedin.com/posts/14th-int…
An interesting short read by @drughunter_com on the kinetics of reversible and irreversible covalent inhibitors including some examples from the industry. It includes links for more in-depth reading.
This Covalent Enzyme Cheat Sheet provides real-world examples to clarify the mechanisms and terminology used in assessing the potency of covalent and non-covalent enzyme inhibitors. Link: drughunters.com/4h4gvWP
This Covalent Enzyme Cheat Sheet provides real-world examples to clarify the mechanisms and terminology used in assessing the potency of covalent and non-covalent enzyme inhibitors. Link: drughunters.com/4h4gvWP
Just got started on BlueSky Social. Come follow me there. @mbogyo.bsky.social
Exciting paper by the groups of Ronald Micura and Alexandra Lusser in @nchembio. Covalent binders to structured RNA based on alkyl halides and alkyl mesylates show engagement of the preQ1 and Pepper aptamers in vitro and in cells. nature.com/articles/s4158…
Interesting paper by a team around Gerald Schweiger in @PNASNews. Interesting insights into the benefits, disadvantages and costs of competitive research funding. Especially interesting to see how much we do not know, about such an important system. pnas.org/doi/10.1073/pn…
Great to see the 3 final nominees for the "Teacher of the Year Award" of our Faculty @LeidenScience, Joost Willemse (IBL), Sander van Kasteren (LIC) and Rob van Wijk (LACDR), being recognized at the New Year's Reception. Huge caongratulations to Rob van Wijk on winning the award!
LED3 hub member Mario van der Stelt represented our network with a great Tuesday Talk at the New Year's Reception of our Faculty of Science @LeidenScience. He talked about his research into better understanding the human brain on the example of endocannabinoid signalling.
Great Tuesday Talk by Mario van der Stelt at the New Year's Reception of the Faculty of Science @LeidenScienceEN. He talked about his research in the context of the @LED3hub on (endo)cannabinoids and their functions in the brain. onlinelibrary.wiley.com/doi/full/10.10…
The @LED3hub is very excited to be a key part of the research theme "Drug Disovery and Development" that was together with the other 5 research themes highlighted by our dean Jasper Knoester as an important priority for the faculty @LeidenScience at the New Year Reception.
The year officially opens at our Science Faculty @LeidenScience. Great to hear our dean Jasper Knoester talk about the highlights of the last year, about the plans for the next, about the power of connections and about the six themes, including @LED3hub, as an important priority.
Join us in Leiden for this exciting meeting on "Drug Discovery and Global Health" organized by @LED3hub and LUCID. Free registration is required.
We are very excited to announce the @LED3hub & LUCID Symposium "Drug Discovery and Global Health" on February 6th with keynotes @Kelly_Chibale and Paola Picotti @Picotti_Lab as well as an amazing lineup of further speakers. Free registration is required. universiteitleiden.nl/en/events/2025…
Angewandte Chemie @angew_chem
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Nature Chemical Biolo... @nchembio
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Eevweavee @Eevweavee778
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🇵🇸 Ashraf from ... @ashrafsafy80
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Aayush Anand @aayush_anand_
42 Followers 415 Following Ph.D., IIT Patna '26 | https://t.co/pQyD9yh4yu., IIT Delhi '22 | Polymer Chemistry | Organic Synthesis | Macromolecules | 👨🔬
Sudirwan @Panduan_Tut09
268 Followers 5K Following "Panduan dan Tutorial: Temani Langkahmu Menuju Keahlian!" Tema konten ini menghadirkan langkah2 "
Md. Badu @BaduMd1527
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thedreamyguy @alexhthe
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Corynne Adanho @AdanhoCory30912
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Ganesh P.Shinde @GaneshPShinde5
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AROGUNDADE MUIDEEN TU... @DMuideen
494 Followers 7K Following
Claudine Greenwood @_Deenwood
6 Followers 26 Following ~ PhD student in Chemical Biology ~ GSK/University of Strathclyde
Dinesh @dinesh788111
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HumanNo @k89499
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Angewandte Chemie @angew_chem
114K Followers 3K Following Angewandte Chemie, a journal of the German Chemical Society (GDCh, @GDCh_aktuell) - a leading journal in #chemistry published by @WileyGlobal in @Weinheim
Ingo Hartung @HartungIngo
17K Followers 796 Following discovery chemistry nerd @Merckgroup; oncology, immunology, targeted protein degradation, ADCs; soccer, politics, tapas can slip into the feed; my own views
Dan Nomura @DanNomura
19K Followers 9K Following Professor of Chemical Biology and Molecular Therapeutics at UC Berkeley; Departments of Chemistry and Molecular and Cell Biology; Co-Director of @MTI_UCB
Olalla Vázquez @OlallaLab
8K Followers 4K Following Professor of Chemical Biology at @Uni_MR. Optochemical tools for controlling biological processes at molecular level. Epigenetic chemical probes. Be Light!✨✨
Craig Crews @CraigMCrews
9K Followers 935 Following Yale Professor, Founder of @ArvinasInc, Halda Therapeutics, https://t.co/YoR6Yo3d3u, @[email protected]
Guillaume Laconde @Glaconde34
5K Followers 99 Following Medicinal chemist, PROTAC and #TPD technology OXELTIS Scientist, https://t.co/F8c4eERuOA Communication Deputy for the SCT, https://t.co/8j34whJXIQ Tweets = my own.
Jeremy Baskin @basktastic
5K Followers 1K Following Click chemist, cell biologist, #chembio & #lipidtime enthusiast, occasional classical pianist (he/him). Also @[email protected]
Stuart Schreiber @SchreiberStuart
17K Followers 381 Following Truth-seeking scientist; equal parts Cajun, Mississippian, Irish, Hungarian.
Covalent Modifiers @CovalentMod
4K Followers 313 Following A feed for the blog https://t.co/pXYAKACULR. Discusses the covalent modification of proteins. Available on bsky and mass std don
ChemBioChem @ChemBioChem
11K Followers 2K Following Showcasing breakthroughs at the interface of chemistry & biology #ChemBioChem. We have changed our X account. Find our latest updates on @ChemEurope.
bryan dickinson @chembioBryan
6K Followers 1K Following chemical/synthetic biologist, Luddite trying find better ways to make molecules that do important stuff, dad, @uchicago professor of chemistry
Dirk H. Trauner @DirkTrauner
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Gasser Group @GasserGroup
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Nature Chemical Biolo... @nchembio
26K Followers 563 Following A scientific journal devoted to publishing the most compelling research, opinion and analysis at the intersection of chemistry and biology.
MaulideGroup @MaulideLab
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Grossmann Lab @TomNGrossmann
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291 Followers 764 Following #father #postdoc #chemist #catalysis #artificialmetalloenzymes #ArM #chemocatalysis #biocatalysis @stratinghinst @roelfesgroup alumni @RWTH
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Andrey Klymchenko �... @aklymchenko
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183 Followers 668 Following Research track faculty @Umich @UMichPharmacy | Former Postdoc @MGHCancerCenter @ljiresearch | interested in immunology and chemical biology
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Anywhere Chemistry Ev... @AnywhereChem
1K Followers 161 Following Aggregating online ChemEvents (seminar, poster, conferences), to bring chemists together. Please tag (free, online) events #AnywhereChem and we'll share!
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Koninklijke Nederland... @_knaw
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