🎉Today our paper on single vector CRISPR/Cas9 gene editing 🧠🧬 and marker gene expression is available on @biorxivpreprint! This is my 1st lead author paper in @BryanCopits lab, and was a collaboration with @Meaghan_Creed's lab! Check out the tweetorial! biorxiv.org/content/10.110…
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1/ Gene editing is crucial for understanding the nervous system, and existing tools to manipulate genes have different strengths and drawbacks. Global knockouts eliminate a gene in every cell of an animal, while Cre-lox approaches can offer more cell-type or regional specificity.