Richard Fuisz @richardfuisz
Asking biotechnology (politely) to do useful things. | Future House, Arcadia Science, Templa Nucleics. fuisz.xyz San Francisco, CA Joined August 2015-
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Lol, awesome.
I discussed the data behind the recent anti-cavity Lumina treatment. TLDR: while the approach looks promising and self-experimentation is cool, most of the direct data comes from small studies in rats and well... most humans are not rats. writingruxandrabio.com/p/on-lumina-an… What's more, I…
Classic example of candidate gene BS -- the only study i know of that shows NPSR1 was based on 2 short sleepers in a family that shared the mutation, and some loosely suggestive mousework. Doesn't validate in UKBB afaik.
Classic example of candidate gene BS -- the only study i know of that shows NPSR1 was based on 2 short sleepers in a family that shared the mutation, and some loosely suggestive mousework. Doesn't validate in UKBB afaik.
LRP5 G171V carriers also get very, very big jaws & bone growths on the roof of their mouth that can interfere with speech -- I'm not sure this one is a slam dunk unless you expect to have routine exposure to high speed collisions.
LRP5 G171V carriers also get very, very big jaws & bone growths on the roof of their mouth that can interfere with speech -- I'm not sure this one is a slam dunk unless you expect to have routine exposure to high speed collisions. https://t.co/wXJEm9zUU0
All drugs (recreational, medical, etc) should be legal for anyone over 90 years old
calling it now: b463e0d292b9dae8288ba300e2c6bb4583ddd5d023580e86e2d94cc4518a9012
About to leak some serious alpha here: SF has only 1 DMV location. It can be a few hour wait if you’re unlucky. But nopalito across the street has the best Mexican food I’ve ever had, and no one minds if you grab a number, eat, and come back an hour or 2 later.
new baker lab banger dropped: biorxiv.org/content/10.110…
Yikes
the whole field of genetics was done in the wrong order. should've developed NGS before human genome project, should've built big biobanks before spending all that time on candidate genes....
Michael Nielsen @michael_nielsen
96K Followers 6K Following Searching for the numinous 🇦🇺 🇨🇦, home in 🇺🇸 Research @AsteraInstitute https://t.co/maezekzRUb
Tony Kulesa @kulesatony
8K Followers 2K Following biotech startups @pillar_vc and @petribio Prior: @MIT, @BroadInstitute
Sebastian S. Cocioba�.. @ATinyGreenCell
24K Followers 8K Following Amateur 🌿 Biologist • Aspiring 🌺 Designer Researcher at Binomica Labs • Degreeless Heathen • Petunia Breeder • Open Lab Notebook: https://t.co/umYTLluuuw
Prachee Avasthi @PracheeAC
25K Followers 8K Following Co-founder & CSO @ArcadiaScience. Head of Open Science @AsteraInstitute. Immigrant. she/her
Niko McCarty 🧫 @NikoMcCarty
23K Followers 861 Following Writing and editing stories about scientific progress, especially in biology. Founding Editor @AsimovPress Head of Creative @AsimovBio
Rachel J Dutton @racheljdutton
4K Followers 2K Following Science Resident @AsteraInstitute, cheese microbiologist, former Scientist @ArcadiaScience + Professor @UCSanDiego
Ruth Hook @ruth_hook_
12K Followers 1K Following immunology & stem cell biology- tissue culture in startups and basic research 🇺🇸🇮🇪🇫🇮 citizen- reading, running, climbing, paleontology, folk harp etc
Adair Borges @AdairLBorges
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Arye Lipman @aryelipman
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Kat @KKajderowicz
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Sam Rodriques @SGRodriques
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Mike Solana @micsolana
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Daniel Goodwin @D_R_Goodwin
2K Followers 732 Following I like biology, computers and type-2 fun. Previously @MIT, now @HomeworldBio, personal 📜 at https://t.co/xdDQRay9XA
Cameron Dale MacQuarr.. @cdmacquarrie
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Andy Matuschak @andy_matuschak
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Elliot Roth || SF @ThatMrE
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Darcie Desroches @DarcDesroch
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Aryan @takeitasjoke
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a @yuboaustin
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Isaac Wilks @wilks_isaac
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virajcz @virajcz
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Michael Trịnh @MichaelTrinh18
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Aydin @aydinwastaken
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Rhythm Doshi @RhythmDoshi
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Fred Ehrsam @FEhrsam
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Samuel Stolle @vollkorn_toast
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derek @mybldyvlntne
181 Followers 693 Following Loveless (stylized in lowercase) is the second studio album by the Irish-English rock band My Bloody Valentine. It was released on 4 November 1991 in the United
Poppy-rose Allemond @PoppyAllem
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Alyth Rubenfeld @ARubenfe
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gracchusbabeuf @weltsterngeist
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Jay Chia - getdaft.io @JayChia5
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Terapeuta Rafael Cast.. @RafaelFdeCastro
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Caitlin M. MacCarthy @seemaccarthy
115 Followers 303 Following '..what darkness the mind of a great discoverer must grope, and what false tracks they will follow, before they see the light of truth.' ~Nature, Dec. 1920
Jack @Jack51153846
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Críscia Luana Olivei.. @LuanaCrisc85436
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Jeferwon @dddiefso
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Aynara @psicaynara
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Pt T @Ppmt777
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Marcela @Marcelapsi28
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Elliot Hershberg @ElliotHershberg
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Michael Nielsen @michael_nielsen
96K Followers 6K Following Searching for the numinous 🇦🇺 🇨🇦, home in 🇺🇸 Research @AsteraInstitute https://t.co/maezekzRUb
Celine Halioua @celinehalioua
31K Followers 3K Following Founder + CEO @loyalfordogs 🐶 Working on aging drugs! Longevity Fund, @UniofOxford health econ, @UTAustin neuroscience. Write to learn things.
Tony Kulesa @kulesatony
8K Followers 2K Following biotech startups @pillar_vc and @petribio Prior: @MIT, @BroadInstitute
Patrick Hsu @pdhsu
30K Followers 3K Following co-founder @ArcInstitute, @BerkeleyBioE professor | researcher & investor in genome editing, biotech, AI | 🇨🇦 @harvard @broadinstitute @editasmed, Fast Grants
Sebastian S. Cocioba�.. @ATinyGreenCell
24K Followers 8K Following Amateur 🌿 Biologist • Aspiring 🌺 Designer Researcher at Binomica Labs • Degreeless Heathen • Petunia Breeder • Open Lab Notebook: https://t.co/umYTLluuuw
Prachee Avasthi @PracheeAC
25K Followers 8K Following Co-founder & CSO @ArcadiaScience. Head of Open Science @AsteraInstitute. Immigrant. she/her
Noah Smith 🐇🇺�.. @Noahpinion
321K Followers 1K Following Writes about economics, posts about rabbits. For serious opinions/analysis, read my blog: https://t.co/KfUxUlCYPz
Vega Shah @dr_alphalyrae
12K Followers 3K Following life sciences software 🧬 product strategy 👩🏻💻 writer & futurist 🚀 previously scientist at @JGI, @UW & @UCBerkeley 👩🏻🔬 views are all mine ✨
Ben Reinhardt @Ben_Reinhardt
10K Followers 522 Following Dare mighty things! Journeyman wondersmith @spec__tech. Past: AI @MagicLeap, Space Robots @NASA + @Cornell, medieval history @Caltech 🏴☠️🪐🐉
Balaji @balajis
1.0M Followers 4K Following Immutable money, infinite frontier, eternal life. #Bitcoin
Niko McCarty 🧫 @NikoMcCarty
23K Followers 861 Following Writing and editing stories about scientific progress, especially in biology. Founding Editor @AsimovPress Head of Creative @AsimovBio
Prophetic @PropheticAI
17K Followers 12 Following We are a non-invasive (tFUS) neurotech company building a device to induce conscious experiences.
Jack O'Meara @Jack_O_Meara
2K Followers 2K Following Cofounder & CEO @OchreBio, developing medicines for liver diseases. ☘️
The Thought Emporium .. @EmporiumThought
12K Followers 116 Following As close to a real mad scientist as you'll find | Youtuber | Researcher
The Los Angeles Proje.. @WeBuildLife
113 Followers 5 Following We are building better life & better worlds through our automated scalable embryo editing platform with the goal of artificial biological intelligence by 2030
People Selling Mirror.. @SellingAMirror
186K Followers 900 Following Sometimes when people sell mirrors online, they can't figure out how to get out of the way.
Barak Ravid @BarakRavid
316K Followers 788 Following Political reporter for Axios covering foreign policy & the 2024 election. CNN analyst. Washington correspondent for Walla. Author of Trump's Peace. link in Bio
Will McCreadie @McCreadieWill
795 Followers 149 Following Global Resilience @generalcatalyst - climate, defense and industrials | Prev @Lux_Capital
Brie Wolfson @zebriez
9K Followers 1K Following weird & warm, used to @stripe @stripepress @figma and wax about company culture (https://t.co/r0dbKeCSRE)
Martin Shkreli (e/acc.. @MartinShkreli
168K Followers 3K Following https://t.co/lzin5ByH0t [email protected] https://t.co/oMIiyJcIzk https://t.co/DuU6MMqcgQ
Woolf @WoolfUniversity
5K Followers 27 Following Our mission at Woolf is to increase access to world-class higher education and ensure that it is globally recognized and transferable.
Ron Leuty @rleuty_biotech
11K Followers 2K Following #Biotech reporter @SFBusinessTimes; hardcore @Tigers fan; once rolled a 288. Tip me: [email protected], Signal or 415-722-2678. Also find me on Post.
Marko Jukic @mmjukic
8K Followers 74 Following Finding the golden path to interstellar civilization. Senior Analyst @bismarckanlys.
Amy Lu @amyxlu
2K Followers 1K Following CS PhD student @berkeley_ai, AI for drug discovery @PrescientDesign. Prev: @GoogleAI @insitro @UofT 🇨🇦
Alex S. Araki @alexsaraki
115 Followers 269 Following Animals + Gene Therapy | in vivo pooled screening @Gordianbio | 🇯🇵 | always writing...
Michael Joseph Rosent.. @micimize
159 Followers 118 Following ML Research Engineer @imbue_ai. The guy with the dog. @software_daily maintainer. Views my own but by all means help yourself.
Julie Xu @juliexu_
743 Followers 1K Following Lead product designer @Cartainc, lead vision and strategy workshops @rethinktalks, laserist/events at Titanic’s end, Prev. evolutionary biologist
FutureHouse @FutureHouseSF
2K Followers 3 Following Philanthropically-funded moonshot building semi-autonomous AI to accelerate the pace of scientific discovery in biology.
Noémie Federico @FedericoNoemie
765 Followers 352 Following Helping Founders build in the US @beondeck | O1 extraordinary alien 🛸🇺🇸🦅| culturally confused, linguistically challenged
Physical Intelligence @physical_int
4K Followers 8 Following Physical Intelligence (Pi), bringing AI into the physical world.
Dr. Shelby @shelbynewsad
2K Followers 2K Following Imbibing life and science in equal parts. Investor @compoundVC | Writing https://t.co/5sTPXkv3ML | Cambridge PhD @plantsci | @OhioState Biochem
Avni Barman @avnibarman_
4K Followers 849 Following building @gensheinc | prev product/eng @Confluence @LinkedIn | @USCIovineYoung
Alex Klokus @AKlokus
3K Followers 3K Following Founder and Managing Partner, SALT Fund. Past: Founder @Futurism & Founder @Gravityblankets. I'm old, but I'm young.
ringwiss @ringwiss
17K Followers 175 Following 🏳️🌈 🇪🇺 🇵🇱 🇬🇧 He/him. Armchair parliamentarian. I type at 140 wpm. RTs are endorsements.
Eric Betzig @Eric_Betzig
1K Followers 17 Following An engineering physicist sometimes masquerading as a biologist or, on one occasion, a chemist. Aspiring astronaut. Nuclear is the way.
SpaceAix @cathcoste
6K Followers 1K Following My pre-teen students want to be the #JulesVerne of genomics 🚀 writing our own #ScienceFiction Early #MOOC adopter: MITxBio 7.00x, 7.28.1x-2x, 7.QBWx certified
Andreas Ehn @ehn
13K Followers 2K Following Co-founder of Wrapp, ex-Spotify CTO, ex-Stardoll. Technologist, advisor, angel. Values freedom. If you're wondering if a tweet was sarcastic, the answer is yes.
~~datahazard~~ @fentasyl
97K Followers 301 Following ~~ Stats ~~ Civil Rights ~~ Victim Advocate ~~ ~~ ~~ eth: 0xfFFfFfFfFF4bf6A4F2217d6250754B5e937819cb
Elon Musk @elonmusk
181.6M Followers 584 Following
Arezoo Arvandd @arezou_arvand
156 Followers 1K Following MSc.Biochemistry, MUN. @kakumanilab currently exploring what small non coding RNAs do in gene regulation and what kind of proteins are helping them!
Anatoly Karlin 🧬�.. @powerfultakes
36K Followers 712 Following 💛#immortality 🧠#iq 🧬#DeSci 💸#UBI 🐘#uplift 🤖#xrisks Accelerating IQ 🧬⏩ @thesophiadao 🏴🐍🌐🏳️🌈 / https://t.co/DTxJo11vzk / https://t.co/TDNXvRMPx6
John Carmack @ID_AA_Carmack
1.1M Followers 241 Following AGI at Keen Technologies, former CTO Oculus VR, Founder Id Software and Armadillo Aerospace
Richard Ngo @RichardMCNgo
35K Followers 1K Following What would we need to understand in order to design an amazing future? Figuring that out @openai
alex rubinsteyn @iskander
5K Followers 4K Following Genomics + immunology + ML = personalized cancer immunotherapy. @CompMedUNC @UNC_Lineberger @OpenVax https://t.co/8DWibdgbLI
Derya Unutmaz, MD @DeryaTR_
290K Followers 4K Following Professor, medical scientist, immunologist @jacksonlab research in aging & cancer immunotherapy. Interests: #longevity #robotics #AI #Scifi #tech #space🇺🇸🇹🇷
Eric Frank @IHaveSweaters
848 Followers 3K Following research scientist, formerly founding team @ uber ai labs & @ml_collective & geometric intelligence, ex toy designer @KiteandRocket 🌈✡️
Amit Deshwar @AmitDeshwar
460 Followers 1K Following
Tom Ellis @ProfTomEllis
23K Followers 602 Following Synthetic Biology & Synthetic Genomics @ Imperial College London and the Sanger Institute. Bilingual in English and DNA. Also at https://t.co/f2Na2PES8R
Crémieux @cremieuxrecueil
88K Followers 902 Following I write about genetics, 'metrics, and demographics. Read my long-form writing at https://t.co/8hgA4nNS2A.
andrew chen @andrewchen
285K Followers 12K Following 🇺🇸 General Partner @ a16z. Investing at the intersection of TECH x GAMES.
megabase @the_megabase
517 Followers 254 Following genomics/bioinformatics lackey, aDNA enthusiast. weakly penetrant. 3rd-generation denisovan-american. proud carrier of 16 hom LoFs
Andrew Côté @Andercot
64K Followers 1K Following engineering physicist, founder Hyperstition Inc, scout @a16z, runs @TheAISalonSF, deep-tech, physics, energy and sci-fi 🇨🇦
ShayanRabbi @TheShayanRabbi
257 Followers 939 Following 🤡🎪 or 🏥💊 Genetics & Philosophy |Start Up in Stealth| Researching at @SickKids & @UHN | Ajmera Transplant Center | @UofT | Thoughts be my own
Matt Durrant #hiring @mgdurrant
852 Followers 457 Following Mobile genetic element whisperer. Computational Biologist @arcinstitute. Genetics PhD @StanfordMed I post about programmable recombinases and genome design.
David Fajgenbaum, MD @DavidFajgenbaum
11K Followers 3K Following @Penn physician-scientist-patient who 'cured thyself' | Advancing @CureCastleman + @EveryCure | National Bestseller #ChasingMyCure https://t.co/26OS13etrF
@gregisenberg The VCs who take August off (and more) are gonna have a hard time now that folks are keeping score — in public:
28. Windows of Costa Nova, Portugal
@seemaychou Good to know! I was thinking of @AndrewGYork's super cool GitHub paper format, which I really love a lot of features of but just wish they could get served to me through the same search engines I use to explore the literature
@MWCvitkovic @AdamMarblestone Macaques are more like $15k - $20k per animal now, but I think of it more as ~$1M per year for minimum viable macaque program. Incremental costs come down but a lot of overhead. Smaller NHPs (marmosets/tamarins) have far, far lower overhead
Life never left the ocean, we just evolved a way to carry little sacks of ocean around us in a skinbag
@Willyintheworld Big Chimpanzee doesn’t want you to know we cracked chimp-to-human xenotransplantation 60+ years ago before the advent of modern immunosuppressives and then inexplicably dropped it for reasons
It is really odd that Apple has accidentally designed computers that are really good for LLM inference Like imagine if the fastest car in the world had actually been intended as an ice cream truck
@yacineMTB you might prefer to use ip over thunderbolt, ethernet is too slow
Now imagine being a 3 year old elder spider in central Colombia who has lived in a dark cave for all its life, catching and eating bugs, looking forward to the rainy season when the crickets would come back to mate. And imagine if in a week a tree that once provided shade to the…
Imagine being a 70 year old retiree in Japan who dutifully worked at Toyota for 45 years and who was looking forward to a peaceful if plain life living off the yen denominated fruits of your labor. And imagine if in a week your entire life’s savings devalued 5% because of…
Really cool to see Gordian’s platform launch today. I always thought in vivo perturb-seq seemed nearly impossibly hard to use in a drug development setting, but they’re doing it! Finding targets! Excited to see where it goes!
Shouldn’t aging be part of drug discovery for diseases of aging? gordian.bio/blog/introduci… Gordian exists to move therapeutic testing from plastic wells and young mice into a living environment with all the complexity present in patients with age-related disease. We’re now…
Shouldn’t aging be part of drug discovery for diseases of aging? gordian.bio/blog/introduci… Gordian exists to move therapeutic testing from plastic wells and young mice into a living environment with all the complexity present in patients with age-related disease. We’re now…
Americans have had their brains rotted by courtroom dramas into believing that it’s difficult in the average case to figure out who committed a crime and that you have to be really clever and trick criminals into giving themselves up, when the reality is that criminals are so…
It is amusing that, for example, of the 2 approved treatments for age-related lung fibrosis (nintedanib and pirfenidone) - clinicians have no idea for how either of them work. And, in contrast, all the treatments for which we had “rationale” (eg Pamrevlumab) failed IPF trials…
Every IV bag, every tube, every surface, every lotion, every calorie of food that premature babies touch in the first period of their lives is full of hormone disrupting chemicals that provably distort their neurological and reproductive development — this is our world
@rajathx Use computer models and organs-on-a-chip to invent chemistries that 1) fulfill industrial requirements and 2) are much less bioactive Then sell into the supply chain
This is something that I’m currently working through right now but would love help on: making sure I’m compliant with regulations for very small quantities of organic synthesis in an industrial/R&D-zoned space before I buy anything. @sethbannon @fiftyyears @richardfuisz and…
@DevonIanDon @mike_feigin Benchling, as a web service, is pretty slow in its functions (literally, as in it takes time to load things etc) so I prefer to make things faster and highlight+build manually, the rules of primer design are simple enough that I haven’t had issues doing this
@mike_feigin dump reference sequence into benchling —> highlight area that looks 20ish bp and 50ish% GC to capture my region of interest —> copy paste into IDT —> order
The more I use Llama 3 the more I think that Zuck may have just killed OpenAI and all other large proprietary AI vendors. The gap between latest GPT4 and Llama 70b is virtually non existent. Even if OpenAI releases GPT5 now, 400b Llama 3 is still training and will most likely be…
Find what makes you dream.
One of the first projects we took on at @ProfluentBio was designing novel gene editing proteins with language models. This grew into an initiative called OpenCRISPR, and today I’m excited to share that work (including the sequences we designed)! biorxiv.org/content/10.110…
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