Boris Djordjevic @longevityboris
Entrepreneur, Investor & futurist advancing longevity, partial reprogramming & preventive medicine. borisdjordjevic.com London Joined July 2023-
Tweets269
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Following79
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Thank you @trq212 @bcherny .. I was out of usage for Fable 5, then in the last hour I noticed I've got around 20-30% extra usage. Also the usage doesn't seem to go up as fast now (maybe low usage time?) Not a full reset, but very thankful for this extra boost 🙏
@boldceo @JakeBuildThings @bcherny @claudeai Get opus to read the code base, identify or familiarise itself with the problems, fable to prepare the solution and opus to execute it.
@agingroy @Conception One of the fascinating things is the queen of naked mole rats, which this exceptional fertility that does not seem to decline with age, can we translate this to humans?
@BBNTimes_en I've seen her talk about AI and I'm just as impressed of her as a speaker and entrepreneur!
OpenAI built GPT-4b with @RetroBio_ to optimise OCT4 reprogramming. 199 Bio is working on the same problem. @sama, would you open it up more broadly?
@xeniatchoumi Wow wow! You're welcome 😍🥰
Digital creators are pivoting from luxury into AI and tech. @xeniatchoumi at Cannes this week is one of the cleaner examples.. buried in this piece is her move into AI and digital entrepreneurship. Who else is doing both lanes at once?
Xenia Tchoumi made a highly visible return to the 79th Cannes Film Festival this year as an official guest of Campari, continuing her long-standing positioning at the intersection of luxury, business, fashion, and modern digital entrepreneurship. bbntimes.com/society/xenia-…
Retatrutide. 28.3% weight loss. 70 pounds average. TRIUMPH-1 Phase 3, published yesterday. Every headline says “triple agonist.” Almost none explain why the third receptor changes everything. Ozempic and Mounjaro suppress appetite. That’s the GLP-1 and GIP part. Retatrutide adds a glucagon receptor. Glucagon doesn’t kill your hunger. It raises your resting energy expenditure. Your body burns more calories doing nothing. Two fronts: eating less AND burning more. That’s why retatrutide posted 28.3% vs Mounjaro’s 22% vs Ozempic’s 15%. The gap is in the mechanism. Phase 2 showed 24%. Phase 3 beat it. The high-BMI group lost 85 pounds over two years. Nearly half of all participants lost more than 30% of their body weight. I ranked 9 drugs chasing Ozempic’s market a month ago. Retatrutide was #2. The full pipeline, with every mechanism and timeline, is below.
3 years ago, the obesity drug market was basically Ozempic. Today, it's 9 drugs deep in late-stage. Here's what each one actually adds: 1. Foundayo: latest oral GLP-1. @US_FDA approved April 1, 2026. Injections become optional. 2. Retatrutide: 24% weight loss at 48 weeks
The thing I love most is going deep into many fields at once, then watching the connections appear between them. AI has just made that possible at a scale we never could have imagined
Vaccines that protect against Alzheimer or Dementia -- this is only the beginning.
The strongest evidence-based tool for preventing Alzheimer’s and dementia may already be sitting in your shot record. 104 million people. 8 vaccines. All showing protection against brain diseases they were never designed to prevent. Ranked by how much they lower Alzheimer’s and
I've built for myself very valuable helpers, e.g. CLIs or agent skills across several github accounts and orgs. They've been immensely helpful. I've built a CLI for managing X that's far above any other product or paid SaaS; there's been little traction. On the other hand, getting thousands of github stars then promoting your tool creates just so much more traction and adoption, it just doesn't make sense not to do it. If I cared about people using what I built, getting more stars to support my application to work at Anthropic or raise money for a specific project, I would totally buy stars. I don't. Anyhow, on X, you can boost your posts. On github, you can't bost your repos. *wink* hidden opportunity *wink*
@CGrovesNLN If it's in context of power/strength/fatigue, albeit a different mechanism, I've had success with acetylcholin precursors (particularly alpha GPC)
Genuine question: what's a thing you've been trying to find or figure out for weeks/months and just can't get a clear answer on?
@Gazucillo coincidentally I'm working on it
@0xSero @badlogicgames Wasn’t Claude (and codex) scrambling and breaking the logs to protect themselves against distillation, from the earlier source code leak?
@martianwyrdlord For certain people with high risk variants of the ApoE gene, eating meat actually reduces the risks of dementia or co hmm cognitive decline. Higher protein intake is also strongly linked with less frailty. This is not promoting health, but political and social agendas.
@AJamesMcCarthy Given the amazing work you’ve been doing I’m sure @elonmusk might sponsor your ticket for that trip.
@Ashwinreads Every once in a while, it's good to have something to reframe your perspective on money, and what it does to us and how it can help us. Nice light reading.
Abhinav Rana @abhinavv_ranaa
0 Followers 22 Following Building @Kayvahealth · your week, explained with scientific research papers · https://t.co/QsUgOKKWB3
The Cat Health Compan... @thecathealthco
46 Followers 57 Following Going beyond nine lives 🐈 🧬 TCHC is developing therapeutics to delay and reverse age-related decline in cats. More details 👇
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CRISPRKing @CRISPRKING
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cjf077 @CJF077
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₿lackthorne AI @BlackthorneAI
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utkarsh @vulbsti
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Nicole Bournias-Vardi... @nbournia
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spdnleo @spdnleo
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Ari Paul @AriDavidPaul
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Robert Lufkin MD @robertlufkinmd
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xenia tchoumi @xeniatchoumi
41K Followers 597 Following Xenia Tchoumi official Swiss-Italian digital entrepreneur & public speaker based in London. #xenia #xeniatchoumitcheva #xeniatchoumi
vitalik.eth @VitalikButerin
6.9M Followers 547 Following I choose balance. First-level balance. mi pinxe lo crino tcati https://t.co/gCQrmCby7P
Bryan Johnson @bryan_johnson
1.6M Followers 662 Following Conquering death will be humanity’s greatest achievement.
Mckay Wrigley @mckaywrigley
228K Followers 374 Following I build & teach AI stuff. Founder @TakeoffAI + @AgentShare.
Ethan Mollick @emollick
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Soham Sankaran @sohamsankaran
3K Followers 6K Following I run @PopVaxIndia (https://t.co/dOKb3wZ7pr) – we develop mRNA vaccines and therapeutics using computational protein design. I write at https://t.co/reAXhjkSrU
Tongyi Lab @Ali_TongyiLab
25K Followers 26 Following We advance the development of ASI and foster open source collaboration towards a smarter future. Discord: https://t.co/BtsFsAUsvT
david @davidtsong
4K Followers 893 Following intern @ maximal | prev at AI startups, VC, and stanford cs DMs open if you want help w/ benchmarks/evals/custom models
Chris Mirabile @SlowMyAge
5K Followers 859 Following Founder/CEO of the only consumer longevity biotech @novoslabs https://t.co/SVNz05kwO7. https://t.co/bROmHZ8F6s tracks how I reduced my bio age 37% across algos
Eric Dai @EricDai_BioE
3K Followers 2K Following bio x tech || per vita ad astra || conversations with biotech pioneers @freeradicalsbio
Dr Kira @drkiratrades
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claire vo 🖤 @clairevo
57K Followers 3K Following building @chatprd • 🎧 host https://t.co/9WUoI4N5GU 👩👦👦 mama 💻 3x CPTO 🧠 pm + eng + ai + startups 😍 @elawless 📱chiefproductofficer on tiktok
Robert Scoble @Scobleizer
591K Followers 52K Following San Francisco/Silicon Valley AI | Robots, holodecks, BCIs, analysis of new things | Ex-Microsoft, Rackspace, Fast Company | Wrote eight books about the future.
Mario Zechner @badlogicgames
55K Followers 1K Following Armin's handler at https://t.co/B05ybKGkzx. Old man yelling at Claudes. https://t.co/Q1wG57v1yc https://t.co/mnOoWUr0TO https://t.co/8i5vIRE0Wn
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11 Followers 68 Following 1 tech startup exit. 2 sci-fi AI novels (Artificial Wisdom, Infinite Wisdom) as Thomas R. Weaver. Now actively building again around agentic AI.
Peter Steinberger �... @steipete
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Ilya · イリア @ilyamiskov
53K Followers 1K Following Visual Designer. Previously @sketch, @frame_io. 📷 Amateur film / digital photographer 🇯🇵 日本語を勉強しています。
Matthieu ❙❙ Eleve... @matt_elevenlabs
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Thariq @trq212
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478K Followers 826 Following Exploring the universe from a backyard in Arizona. Get on my email list 👇
NootBro @nootropicguy
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Morgan Levine @DrMorganLevine
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Zoe (is building utop... @techno0ptimist
3K Followers 426 Following Eternally enthusiastic & self-upgrading 🦄📖 || Longevity, biotech, futurism, H+, agentmaxxing 👾 l| @AevitasHouse + @PrimordiaGrants
@levelsio @levelsio
912K Followers 3K Following 💸https://t.co/sQ0aiU82PA $803K/m 📸https://t.co/lAyoqmT9Hv $88K/m 🎮https://t.co/jFirUbDOjx $44K/m 🏡https://t.co/1oqUgfDEsx $31K/m 👙https://t.co/RyXpqGvdBB + @X $17K/m 🌍https://t.co/UXK5AFra0o $15K/m 🏩https://t.co/4p4dzTEtCE 💾https://t.co/T74ZwJ2cQa
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Agingdoc🩺Dr David ... @agingdoc1
51K Followers 100 Following Longevity medicine best practices | healthspan | precision medicine | bio/acc | consulting @ https://t.co/XWGLGiTnox Connect: https://t.co/wneqWlNToLYou might like
