Laure Wynants @laurewynants.bsky.social @laure_wynants
Assistant Professor Epidemiology @ Maastricht University and KU Leuven / Diagnostic and prognostic modeling / https://t.co/qQOBZtocCb Beringen, België Joined May 2018-
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We looked at dynamic random forest prediction models for central line-associated bloodstream infections on EHR from @UZLeuven. We compared binary, multiclass, time-to-event, and competing risk outcome definitions. With @sibipx @laure_wynants arxiv.org/abs/2404.16127
In case you missed it, already forgot about it or if you are desperately looking for reading material for the weekend: TRIPOD+AI came out this week 👇 bmj.com/content/385/bm…
New update of the TRIPOD+AI statement promotes best practice in reporting clinical prediction models, @TRIPODStatement #AI bmj.com/content/385/bm…
TRIPOD now includes reporting standards for machine learning for clinical applications
TRIPOD now includes reporting standards for machine learning for clinical applications
Also methodology work is often done ‘on the side’ and so can be hard to find dedicated time This is why we desperately need much more funding for methodology research, which after all underpins health research 4/n
From a paper I found today: "The c-index of the model is .794, a value that is only decimals away from what is commonly taken as a good predictive capability" Close but no 🍾!
Er zijn nog vrije plekken voor de Cursus Klinische Predictiemodellen in Maastricht in mei. Deze cursus, waaraan ik naar goede gewoonte ook zal bijdragen, wordt al bijna tien jaar goed gesmaakt door zorgprofessionals en promovendi. klinischepredictiemodellen.nl
Read one of our latest papers by @BarrenadaLasai @pauladhiman @GSCollins @laure_wynants @jan_verbakel and @BenVanCalster which examines the use of ADNEX, a risk prediction model for diagnosis of ovarian cancer. #womenshealth #ADNEX
Academia is: 5% research 5% teaching 20% meetings 20% EMAILS! 5% Reformatting manuscripts 5% Requesting password reminders 10% filling in forms 5% looking for forms/guidance 'on sharepoint' 5% using Google to find forms/guidance on your uni website 20% moaning about academia
Academia is: 5% research 5% teaching 20% meetings 20% EMAILS! 5% Reformatting manuscripts 5% Requesting password reminders 10% filling in forms 5% looking for forms/guidance 'on sharepoint' 5% using Google to find forms/guidance on your uni website 20% moaning about academia
Systematic review with meta-analysis of >30 validations of 1 model: IOTA-ADNEX
Systematic review with meta-analysis of >30 validations of 1 model: IOTA-ADNEX
Discover our latest research in @BMJMedicine! We conduct a systematic review and meta-analysis of external validations of the ADNEX model for ovarian cancer diagnosis, highlighting areas for methodological reporting improvement. bmjmedicine.bmj.com/content/3/1/e0…
Reminded today about how important this paper is by @laure_wynants @BenVanCalster @ESteyerberg @MaartenvSmeden et al "Three myths about risk thresholds for prediction models" Highly recommended reading bmcmedicine.biomedcentral.com/articles/10.11…
NEW PAPER: ✨How do public health researchers interpret regression coefficients?✨ doi.org/10.1186/s12889… Not a survey or quiz, this is qualitative work exploring diverse epistemological and interpretative practice in biostatistics. #statstwitter #epitwitter
In a new article in @SciReports I find that male PhD students are almost twice as likely than female PhD students to obtain a cum laude distinction for their dissertation. A cum laude is very rare, and only awarded to 5% of Dutch PhD students. 1/5 OA: nature.com/articles/s4159…
1 December is the deadline to register for our short course on clinical prediction models and machine learning. We cover model building, validation and beyond, software, and critical appraisal. maastrichtuniversity.nl/epidemiology-c…
Got to meet @MyraMcguinness' hive today!
What a fun experience talking about prediction models the whole day. Exceptional to have such an active and engaged audience asking so many questions! Thanks!
What a fun experience talking about prediction models the whole day. Exceptional to have such an active and engaged audience asking so many questions! Thanks!
#aimos2023, what a treat talks: great people: interesting and kind catering: delicious location: amazing livestream: free
Great presentation by Reese Richardson from @AmaralLab on journal hopping, and the way paper mills persist through de-indexing!! De-indexing is the big red button to acting on paper mills...shows how we need more diverse solutions. #aimos2023
Maarten van Smeden @MaartenvSmeden
42K Followers 835 Following Statistician • associate prof • statistics/epidemiology/AI methodology, Julius Center @umcutrecht • own views
Richard Riley (R²) @Richard_D_Riley
12K Followers 1K Following Prof of Biostats • BMJ Stats Editor • Books: "Prognosis Research in Healthcare" & "IPD Meta-Analysis: A Handbook ..." • https://t.co/8VEMmy3Kfx • Doctor Who ❤️❤️
Gary Collins 🇪🇺 @GSCollins
10K Followers 989 Following Prof of Med Stats @UniofOxford | Director @CSMOxford & UK @EQUATORNetwork | @TRIPODStatement +AI | BMJ Stats Ed | 🚴
Frank Harrell @f2harrell
30K Followers 171 Following Biostatistician/Professor/Founding Chair of Biostatistics, Vanderbilt U. Blog: Statistical Thinking:https://t.co/2BTEONzsfX @f2harrell on https://t.co/bsPN9JQNOS
Stephen John Senn @stephensenn
12K Followers 1K Following CH & UK stats imposter, skier & Munroist: disappointing, humourless, confusing or disingenuous. DOI https://t.co/JN2UJQW1Lg
Peter Tennant @PWGTennant
16K Followers 2K Following Epidemiologist at @LIDA_UK and @TuringInst interested in causal inference. For details of my Intro to Causal Inference Course visit: https://t.co/HfuPIlOxvy
Darren Dahly - on Blu.. @statsepi
28K Followers 5K Following Epidemiologist + Statistician | @HRBIreland @CRF_Cork @UCCPublicHealth @UCC | #ClinicalTrials #EpiTwitter #StatsTwitter Views mine
Jack Wilkinson @jd_wilko
8K Followers 6K Following Stats and methodology. #IVF & #infertility research. Detecting fabricated data. Tweets do not reflect employer opinion. Centre for Biostats, @UoM
Andrew Vickers @VickersBiostats
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Tim Morris @tmorris_mrc
6K Followers 1K Following Principal research fellow @MRCCTU ✦ Work on statistical methods: which ones work well when? ✦ #statstwitter ✦
Demetri @PhDemetri
19K Followers 518 Following Mathematical bohemian par excellence. It’s all just a tool, pick one, punch out, cash your cheque.
Andrew Althouse @ADAlthousePhD
12K Followers 3K Following Statistician @Medtronic, studying novel statistical methods to do more efficient clinical trials; enjoy kettlebells, deadlifts, whiskey, craft beer & food
Kazuki Yoshida @kaz_yos
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Adam Kucharski @adamjkucharski
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Noah Haber @NoahHaber
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Ewout Steyerberg @ESteyerberg
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Karandeep Singh @kdpsinghlab
10K Followers 3K Following Jacobs Chancellor’s Endowed Chair @UCSanDiego. Chief Health AI Officer @UCSDHealth. Creator of Tidier.jl #JuliaLang. #GoBlue. Views own.
Anthony Matthews @_tony_matthews
1K Followers 1K Following Assistant Professor in Epidemiology and Causal Inference @CAUSALab @karolinskainst | long-term SAFC sufferer | 🇬🇧 in 🇸🇪
Daniel Sjoberg @statistishdan
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lisa bodnar @lisabodnar
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Yonemoto N @nyonenyone
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Hung Pham @hhp_9x
96 Followers 386 Following MSc biostat. A #stan stan, #rstats, randomize when you can
Ashar Asif @ashetabulum
187 Followers 773 Following | Radiology Clinical Research Fellow | NHS Clinical Entrepreneur | A fan of:🫀🫁 🧠🦴and arteries, numbers, gadgets and gizmos | Aspiring human plumber |
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Emma Davies Smith, Ph.. @GirlMeetsStats
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ISCB45 @iscb45
122 Followers 103 Following 45th Annual Conference of the International Society for Clinical Biostatistics, 21-24 July 2024, Thessaloniki, Greece
Danielle Oste @Danielle_J_Oste
9 Followers 36 Following Research Assistant and Undergraduate student at The University of Sydney
Mathematics in Medica.. @MMLS_journal
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Leanna @Thadet317578
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BMJ Oncology @BMJOncology
2K Followers 1K Following A new #OA journal from @bmj_company publishing across the broad spectrum of cancer research, investigation, treatment & practice. EIC: Prof Ananya Choudhury
Maite Sanchez-Santos @maytessantos
108 Followers 351 Following Senior medical statistician and epidemiologist at @CSMOxford. Ageing and health.
Jose Benitez-Aurioles @AuriolesJose
34 Followers 115 Following PhD student at the University of Manchester, as part of the HDR UK-Turing Wellcome PhD Programme in Health Data Science
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751 Followers 643 Following UCSF Geriatrics research faculty. Former UCSF Geriatrics clinical and T32 fellow, Duke IM resident, and SLU med student. Tweeting articles about geriatrics.
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193 Followers 201 Following Health researcher, PhD Candidate @TrialsCentre | NextGen systematic reviews, research methods, early childhood obesity prevention #TOPCHILD @CochranePMA
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JM001 @5aaaaaabii
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Selassie Ogyaadu, MD,.. @jsogyaadu
120 Followers 842 Following
Patrick Abraham @PatrickAbraha15
502 Followers 905 Following Health Economist | Global Health | PhD Candidate 🌏🏳️🌈 he/him @HEU_unimelb
Emma Todd, Gut Microb.. @Emma_microbiome
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MUHAMMED TAHIR MUHAMM.. @MTMSUDAIS
197 Followers 950 Following Statistics and Spatial Epidemiology || Spatio-temporal Disease Data || Geospatial Data Analysis and Health Surveillance || Disease Mapping || Biostatistics ||
Rui Wang @RuiWangMD
411 Followers 464 Following Reproductive Epidemiologist @MonashUni | Deputy Editor #HumReprod | Editor @CochraneCGF | Passionate about #RCTs | #metaanalyses | Evidence-based women's health
EPOJ @EPOJ12
464 Followers 4K Following
Pranujan Pathmendra @PranujanP
151 Followers 363 Following Research Enthusiast ~ PhD Candidate #ResearchIntegrity PRIMeR group @syd_health
Maarten van Smeden @MaartenvSmeden
42K Followers 835 Following Statistician • associate prof • statistics/epidemiology/AI methodology, Julius Center @umcutrecht • own views
Richard Riley (R²) @Richard_D_Riley
12K Followers 1K Following Prof of Biostats • BMJ Stats Editor • Books: "Prognosis Research in Healthcare" & "IPD Meta-Analysis: A Handbook ..." • https://t.co/8VEMmy3Kfx • Doctor Who ❤️❤️
Gary Collins 🇪🇺 @GSCollins
10K Followers 989 Following Prof of Med Stats @UniofOxford | Director @CSMOxford & UK @EQUATORNetwork | @TRIPODStatement +AI | BMJ Stats Ed | 🚴
Frank Harrell @f2harrell
30K Followers 171 Following Biostatistician/Professor/Founding Chair of Biostatistics, Vanderbilt U. Blog: Statistical Thinking:https://t.co/2BTEONzsfX @f2harrell on https://t.co/bsPN9JQNOS
Stephen John Senn @stephensenn
12K Followers 1K Following CH & UK stats imposter, skier & Munroist: disappointing, humourless, confusing or disingenuous. DOI https://t.co/JN2UJQW1Lg
Miguel Hernán @_MiguelHernan
44K Followers 194 Following Using health data to learn what works. Making #causalinference less casual. Director @CAUSALab | Professor @HarvardChanSPH | Methods Editor @AnnalsofIM
Peter Tennant @PWGTennant
16K Followers 2K Following Epidemiologist at @LIDA_UK and @TuringInst interested in causal inference. For details of my Intro to Causal Inference Course visit: https://t.co/HfuPIlOxvy
Darren Dahly - on Blu.. @statsepi
28K Followers 5K Following Epidemiologist + Statistician | @HRBIreland @CRF_Cork @UCCPublicHealth @UCC | #ClinicalTrials #EpiTwitter #StatsTwitter Views mine
Eiko Fried @EikoFried
36K Followers 2K Following Associate Prof @UniLeiden. Mental health & data science. Building early warning system for depression (https://t.co/rw3oC2Kol0).
Jack Wilkinson @jd_wilko
8K Followers 6K Following Stats and methodology. #IVF & #infertility research. Detecting fabricated data. Tweets do not reflect employer opinion. Centre for Biostats, @UoM
Andrew Vickers @VickersBiostats
5K Followers 72 Following Biostatistician at Memorial Sloan Kettering Cancer Center. Special interest in prostate cancer, risk prediction, patient-reported outcomes, decision-making.
Tim Morris @tmorris_mrc
6K Followers 1K Following Principal research fellow @MRCCTU ✦ Work on statistical methods: which ones work well when? ✦ #statstwitter ✦
Daniël Lakens @lakens
31K Followers 2K Following Experimental Psychologist @TUeindhoven. Co-host of @nulliusverbapod. Improving Stats Textbook https://t.co/PxngSRZ02S Omnia probate
Demetri @PhDemetri
19K Followers 518 Following Mathematical bohemian par excellence. It’s all just a tool, pick one, punch out, cash your cheque.
Andrew Althouse @ADAlthousePhD
12K Followers 3K Following Statistician @Medtronic, studying novel statistical methods to do more efficient clinical trials; enjoy kettlebells, deadlifts, whiskey, craft beer & food
Kazuki Yoshida @kaz_yos
6K Followers 5K Following Father in Training | Rheumatology & Drug Safety/Efficacy & Clinical Research | https://t.co/WnBbZH5UcY
Noah Haber @NoahHaber
10K Followers 1K Following econ, epi, stats, meta, causal inference mutant scientist, epistemic humility fairy godmother, chaos muppet. doing metasciencey stuff, e-mail [email protected]
Solomon Kurz @SolomonKurz
9K Followers 696 Following Clinical psychology researcher | adjunct professor | applied statistics geek | so called #RStats influencer
Judea Pearl @yudapearl
76K Followers 187 Following Student of causal inference, human reasoning, and history of ideas, all viewed through the sharp lens of artificial intelligence.
Ewout Steyerberg @ESteyerberg
4K Followers 53 Following Methodologist focused on prediction research from biostatistics, clinical epidemiology, and medical decision making perspectives @bds_lumc
Hung Pham @hhp_9x
96 Followers 386 Following MSc biostat. A #stan stan, #rstats, randomize when you can
The Ocean Cleanup @TheOceanCleanup
352K Followers 124 Following The Largest Cleanup in History. Follow the latest updates on our mission to rid the world's oceans of plastic. #TheOceanCleanup
ISCB45 @iscb45
122 Followers 103 Following 45th Annual Conference of the International Society for Clinical Biostatistics, 21-24 July 2024, Thessaloniki, Greece
Margarita Moreno-Beta.. @_MargaritaMB
746 Followers 392 Following Associate Professor in Biostatistics, Co-Director of @CEBU_Melbourne, Investigator Grant Fellow @nhmrc. @unimelb, @MCRI_for_kids & @vicbiostat
Matthew Page @mjpages
2K Followers 347 Following Senior Research Fellow @MonashUni developing and evaluating methods for evidence synthesis. Co-lead of @PRISMAStatement 🌈
Kylie Hunter @KylieEHunter
193 Followers 201 Following Health researcher, PhD Candidate @TrialsCentre | NextGen systematic reviews, research methods, early childhood obesity prevention #TOPCHILD @CochranePMA
Dimitris Bolis @dimitrisbolis
3K Followers 5K Following Postdoctoral researcher studying social interaction and the self, with a focus on neurosocial minorities. Bluesky: @dimitrisbolis .bsky.social
Selassie Ogyaadu, MD,.. @jsogyaadu
120 Followers 842 Following
Patrick Abraham @PatrickAbraha15
502 Followers 905 Following Health Economist | Global Health | PhD Candidate 🌏🏳️🌈 he/him @HEU_unimelb
Emma Todd, Gut Microb.. @Emma_microbiome
183 Followers 282 Following Gut Microbiology PhD student at Food and Mood Centre, Deakin Uni, with a passion for science communication.
Rui Wang @RuiWangMD
411 Followers 464 Following Reproductive Epidemiologist @MonashUni | Deputy Editor #HumReprod | Editor @CochraneCGF | Passionate about #RCTs | #metaanalyses | Evidence-based women's health
EPOJ @EPOJ12
464 Followers 4K Following
Olmo van den Akker @DenOlmo
1K Followers 2K Following Tilburg University: PhD assessing preregistration in psychology QUEST Berlin: Assessing guidelines for transparency and ethics in secondary health data studies.
Tomer Yona @Tomer_PT
602 Followers 2K Following PhD candidate at the @TechnionLive - Israel Institute of Technology. Physiotherapist. Opinions are my own.
Hans Huitink @AirwayMxAcademy
13K Followers 9K Following Anesthesiologist🇳🇱Founder Airway Management Academy non-profit airway teaching #AAF24| Mobile Intensive Care Unit😷🚑🩺 | AirAmbulance🛩 @AirwayTriageApp
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pipiens @pvucks
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@sibipx @BenVanCalster @UZLeuven @laure_wynants I wonder if with this model this could be re-evaluated, but personally my time horizon would be 48-72h. 7 days is a longer time horizon, not sure if it would be the most sensible choice for implementation. Nevertheless I believe exposure duration should be an important predictor.
@BesenBruno @BenVanCalster @UZLeuven @laure_wynants just to set the expectations right, this is a methodological comparison study, not a proposed model for application in clinical practice. more will come on CLABSI. stay tuned! and thanks for the feedback on horizon
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Join us, a new interdisciplinary team critically engaging with #AI, #trust and #implementation in #healthcare settings, led by Rianne Fijten and with strands into #ethics, #STS, and a lot more! I'm also in there somewhere! We have two job openings: 1 academictransfer.com/en/340123/phd-…
Imagine how much time academics would save if every funder & institution worldwide agreed to the same format for a CV? We could even put those saved hours toward, oh i don't know, actual research or teaching perhaps?
This, and also for journal styles, promotion documents, reference letters (or better: just stop with that), etcetera
Imagine how much time academics would save if every funder & institution worldwide agreed to the same format for a CV? We could even put those saved hours toward, oh i don't know, actual research or teaching perhaps?
Very nice to see. Message to AI / ML folks: "Evaluating ... a model [means] estimating model discrimination (eg, c statistic), model calibration (eg, calibration plot, calibration slope), and clinical utility (eg, decision curve analysis)."
NEW PAPER out today in @bmj_latest TRIPOD+AI: reporting recommendations for studies developing or validating prediction models for use in healthcare that use #machinelearning methods bmj.com/content/385/bm… #ArtificialIntelligence #AIstandards #OpenAccess Please share 🙏
I have been an advocate of better transparency in AI reporting for research (ahajournals.org/doi/full/10.11…) and the broader public (medicine.umich.edu/dept/lhs/news/…). Really appreciated the opportunity to contribute to the new TRIPOD+AI guidelines to address the “how”: bmj.com/content/385/bm…
NEW PAPER out today in @bmj_latest TRIPOD+AI: reporting recommendations for studies developing or validating prediction models for use in healthcare that use #machinelearning methods bmj.com/content/385/bm… #ArtificialIntelligence #AIstandards #OpenAccess Please share 🙏
Thanks to all the wonderful collaborators (2/2) @DrHughHarvey @Georg__Heinze @michaelhoffman @eloder @lena_maierhein @Bilal_A_Mateen @MMccradden @DrLaurenOR @JohanOrdish @sherrirose @kdpsinghlab @laure_wynants @patlogullo @JennyCamaradou @naomiclarelee @hans_reitsma
We are currently writing a longer Explanation and Elaboration paper to provide more detailed guidance with examples of good reporting for each item (to appear later this year) in the meantime use the 2015 TRIPOD E&E (tinyurl.com/3a3dv3mj)
Hope helpful 🙏 Fundamentally - If you are struggling mentally with your methods project, then please do speak to others and share the load … as solutions then arise and others can help ease your burden both personally and for the methods problem at hand
Another important coping strategy is to ensure there is a good balance between work & life, so that it’s easier to switch off eg at weekends (still hard!) Also accept the submitted paper or software does not need to be perfect - it’s ok for new research to follow on later 5/n
Also methodology work is often done ‘on the side’ and so can be hard to find dedicated time This is why we desperately need much more funding for methodology research, which after all underpins health research 4/n
The big news is out! We are happy to welcome @ESteyerberg this summer as the new division leader of the Julius Center @UMCUtrecht. Looking forward to the renewed collaboration
Delighted to have picked up Boen & Zahn 1982 but note the previous reader circled this section on "anger" 😟 #statstwitter
LLMs in medicine - what are the risks? One risk I believe we are sleep-walking into is what I call the 'exponential hallucination problem'. Let's assume we have an LLM that can ambiently scribe clinical notes from a consultation, and provide a summary with recommendations.
Congratulations to @GSCollins on his appointment as a NIHR Senior Investigator👋🎉 Wonderful to see three statisticians recognised this year (@DrLauraGray and @Richard_D_Riley)👋🎉 @NIHRcommunity
Today we're pleased to announce the appointment of 43 new NIHR Senior Investigators. 21 have been appointed for a second term. They are among the most prominent and prestigious researchers funded by the NIHR. Read more about the appointments: nihr.ac.uk/news/43-resear…
There is this children's game where you *have* to tell the truth but you don't have to prove it. To win, you have to provide a convincing story of something that is spectacular and unexpected. You lose if you don't Except it is not a children's game, it's academic publishing
Many thanks to @NIHRcommunity @NIHRresearch @NIHR for supporting methodologists on their career pathway - humbled to receive this, & at same time as @DrLauraGray & @GSCollins too Will continue to champion the importance of methodology & high research standards in coming years
Today, @NIHRresearch announced the research leaders receiving the prestigious NIHR Senior Investigator Award🏅 We couldn't be more pleased to congratulate our very own Professors @drmelcalvert & @Richard_D_Riley on this important recognition! Read more: birminghambrc.nihr.ac.uk/brc-researcher…
Congratulations @KSBhui @GSCollins @Richard_D_Riley @gjmelendez
Today we're pleased to announce the appointment of 43 new NIHR Senior Investigators. 21 have been appointed for a second term. They are among the most prominent and prestigious researchers funded by the NIHR. Read more about the appointments: nihr.ac.uk/news/43-resear…
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