Maarten van Smeden@MaartenvSmeden
Statistician • associate prof • statistics/epidemiology/AI methodology, Julius Center @umcutrecht • own views mvansmeden.net Utrecht Joined December 2010-
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@SarwarIMozumder @GSCollins @MaartenvSmeden For evaluation of AI models that aim to estimate individual risk (for either diagnosis or prognosis), we just released a 3-part series on this topic in BMJ tinyurl.com/yrpfhkun tinyurl.com/4jv7bnxe tinyurl.com/n4v3ky73 Hope useful place to start
For anyone still believing that "machine learning methods" and "statistical methods" are well-defined and separable groups of different analytical approaches, feel free to read our paper on this jamanetwork.com/journals/jamap…
The ugly side of academia 👇
The ugly side of academia 👇
Ever need to do many repeated analyses? e.g. power calculations, sensitivity analyses, then speed becomes a crucial! In this blog post I compare newcomers #Julia google's #JAX versus #R for logistic regression TLDR: Julia wins, ~10x faster than R vanamsterdam.github.io/posts/240308-j…
@MaartenvSmeden @UMCUtrecht Happy to confirm my transfer to Julius Center @UMCUtrecht! Looking forward to new collaborations and strengthening connections with many, including @MaartenvSmeden and @CarlMoons. Sorry to be leaving @bds_lumc, after seven great years in Leiden full of new experiences.
The big news is out! We are happy to welcome @ESteyerberg this summer as the new division leader of the Julius Center @UMCUtrecht. Looking forward to the renewed collaboration
Endorsed 👇
Methodology research is an intense process mentally & emotionally - this rarely gets mentioned so thought I would share that it’s something I struggle with personally It’s all consuming as your brain keeps trying to solve problems & generate solutions Exciting & exhausting 1/n
TFW writing a response to peer reviewers x.com/i/status/17716…
TFW writing a response to peer reviewers x.com/i/status/17716…
A Very Short List of Common Pitfalls in Research Design, Data Analysis, and Reporting By @MaartenvSmeden ncbi.nlm.nih.gov/pmc/articles/P…
Nothing is certain except death, taxes and dichotomisation of continuous variables
Not sure why but reading this makes me outraged
Or if you have technical skills: start a start-up proofreader.ai
Or if you have technical skills: start a start-up proofreader.ai
Risk factor studies are the biggest force behind the random medical news cycle
Ok this is bad. However, why does ChatGPT add unnecessary “however” and “therefore” at the start of many sentences?
Ok this is bad. However, why does ChatGPT add unnecessary “however” and “therefore” at the start of many sentences?
There is this children's game where you *have* to tell the truth but you don't have to prove it. To win, you have to provide a convincing story of something that is spectacular and unexpected. You lose if you don't Except it is not a children's game, it's academic publishing
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@SarwarIMozumder @GSCollins @MaartenvSmeden For evaluation of AI models that aim to estimate individual risk (for either diagnosis or prognosis), we just released a 3-part series on this topic in BMJ tinyurl.com/yrpfhkun tinyurl.com/4jv7bnxe tinyurl.com/n4v3ky73 Hope useful place to start
@CarinaCarlaKern been done >> times in humans. Recently organ enriched circulating protein biomarkers have shown some information regarding organ specific drivers of mortality/morbidity. Usually Renal biomarkers are good for all causes Machine learning = statistical modelling @MaartenvSmeden
Love it when the best oasis song of all time comes on pandora
Love it when the best oasis song of all time comes on pandora https://t.co/NloJeQbIqt
@ESteyerberg @MaartenvSmeden @UMCUtrecht @CarlMoons @bds_lumc Wow Ewout. Huge news. Can’t imaging the stuff that you, Carl, and Maarten can do together. Congratulations!
@ESteyerberg @MaartenvSmeden @UMCUtrecht @CarlMoons @bds_lumc great that you're coming!
@MaartenvSmeden @ESteyerberg @UMCUtrecht Excited to see all the advances in prediction modelling that will ensue. I envy the clinicians there.
I should be a bit more like him
I should be a bit more like him
A Very Short List of Common Pitfalls in Research Design, Data Analysis, and Reporting By @MaartenvSmeden ncbi.nlm.nih.gov/pmc/articles/P…
Nothing is certain except death, taxes and dichotomisation of continuous variables
Important message below but infuriating #AI field has to 'discover' this rather than being guided by long-standing stats literature eg, onlinelibrary.wiley.com/doi/10.1002/si… by @GSCollins says: 'Categorising continuous predictors is ... inefficient & should not be used in model development'
Important message below but infuriating #AI field has to 'discover' this rather than being guided by long-standing stats literature eg, onlinelibrary.wiley.com/doi/10.1002/si… by @GSCollins says: 'Categorising continuous predictors is ... inefficient & should not be used in model development'
Interesting paper by @David_A_Jenkins & colleagues 'Comparing Predictive Performance of Time Invariant and Time Variant Clinical Prediction Models in Cardiac Surgery' ebooks.iospress.nl/doi/10.3233/SH…
@MaartenvSmeden Cryptic advice. I don't think they've ever been on a priority list for me and I don't think they will be..
@MaartenvSmeden @sharpmelk Same. I’m not at the point where as like 4th author I’d demand to be removed if Author #1 wants to submit there (tho I would advise against in that situation). But when I’m first or senior, I won’t submit there at this moment in time.
@MaartenvSmeden @sharpmelk Additionally I'm not yet at the point where I absolutely won't cite any of them, but I do it rarely and with *extreme* care. I've been wishing recently there was a way to search the lit filtering out certain publishers. Does this exist?
@MaartenvSmeden In a few months Peer Review(tm) will be a hellscape of chatbots reviewing chatbots, featuring greatest hits, such as: "Certainly I can summarize the findings..." "Sorry, as an LLM I am unable to..." "As an AI language model, I can provide some general guidance on assessing..."
@MaartenvSmeden I’m enjoying it, but also noticing that many of the papers are *about* Chat-GPT, and are simply quoting this output — not trying to fake a paper.
it's been a decade since everyone was talking about "big data" and personalized medicine at every conference and I love how that resulted in healthcare becoming approximately 0% more informed by individual genetics & life history outside of tumor markers
Als Touzani komt kijken, maar je bent zelf geblesseerd 🤕 #psvroda #armschaapje