Molecular Systems Physiology Group @ines_thiele
Ines Thiele - Molecular Systems Physiology Group with expertise in modeling of human metabolism, gut microbial metabolism and of the diet-gut-health axis. thielelab.eu Ireland Joined March 2014-
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It's here! "Precisely: A Precision Medicine Podcast from Systems Biology Ireland" is available now on @Spotify, @ApplePodcasts & @SoundCloud! RTs appreciated! Ep. 1: The Origins, with Walter Kolch & Frank Gannon @gannonqimrb @PrecisionOncIre #SBIpodcast on.soundcloud.com/X5PLi
Some time ago, IBM decided not to continue their support for a MATLAB interface. If you use IBM Cplex for metabolic modelling, please vote or comment on this on the IBM website here: ibm-data-and-ai.ideas.ibm.com/ideas/CPLEX-I-… to bring this interface back! Please RT!
🔬 Ready to delve into metabolic microbiome-host interactions? Embark on a PhD adventure at @kieluni, Germany! Explore Hydra's bacterial dynamics using metabolic modeling in a great team. Apply here: lnkd.in/eTKju6SZ #MicrobiomeResearch #PhDposition Please RT
The first use of constraint-based #microbial community modelling on a person with gastrointestinal inflammation has been reported by @uniofgalway @RyanInstitute @vmh_life scientists @ines_thiele 🦠 Dive into the study here 👉 bit.ly/43FjCNB #SDG3
🥳🦠Happy #WorldMicrobiomeDay from #Virtuome2023! In 4 consecutive years our 74 alumni advanced research along the host-microbiome-diet-drug interactions and involved >1000 community participants! @WMicrobiomeDay @Pharmabiotic @ines_thiele @GalwayCMNHS #WMD2023 #Microbiomes4Life
Research Highlight from Lin Tang: @ines_thiele and colleagues present AGORA2 (assembly of gut organisms through reconstruction and analysis, v2), an expanded resource of genome-scale metabolic reconstructions of 7000+ human gut microbes. nature.com/articles/s4159…
In new research from @RyanInstitute @uniofgalway scientists @ines_thiele, a nutritional algorithm capable of identifying dietary intervention strategies was developed and tested against two genome-scale metabolic models 💻 Check out the study here 👉 bit.ly/3Kvjo64
Individualized (personalized) medicine has traditionally included gene-drug interactions (pharmacogenomics). Now add gut microbiome-drug interactions nature.com/articles/s4158… @NatureBiotech by @heinken_almut @ines_thiele and colleagues
Now we can seriously start thinking of getting the most suited (personalized) fermented food consortium each morning nature.com/articles/s4158…
Thank you very much!
I am excited that this resource is finally published. It is the work of many amazing scientists. Thank you so much! The resource can be bulk downloaded here: vmh.life/files/reconstr…. @heinken_almut @johannes_hertel @ERC_Research
I am excited that this resource is finally published. It is the work of many amazing scientists. Thank you so much! The resource can be bulk downloaded here: vmh.life/files/reconstr…. @heinken_almut @johannes_hertel @ERC_Research
Our newest (pre-print) work on microbiome & whole-body metabolic modeling! We demonstrate how personalized, longitudinal modeling of a patient givse unprecedented insight into microbial & host-microbiome metabolism. With @AriannaBasileCC, @lsmarr & others tinyurl.com/26njp523
Very happy to finally see this published @NatureMicrobiol with @MaayanLevy_Lab, studying the vaginal metabolome during pregnancy and in preterm birth. Work led by the fantastic @WilliamKindsch1, @FedBld and Martin Liu. Short thread of key results: nature.com/articles/s4156…
Doing microbiome research and looking for your next career move? Come and join us at APC Microbiome Ireland @Pharmabiotic for a permanent full time position as Lecturer in Microbiome and Health. Please retweet ucc.ie/en/futures/foo…
Last week we welcomed 102 #COBRA community members from 48 institutions from all across the 🌎 in sunny #Galway for #COBRAcon2022. Thank you all for making this conference a huge success! @ines_thiele @GalwayCMNHS @Pharmabiotic @RyanInstitute @ERC_Research @GalwayBayHotel
Join us for #COBRAcon2022 in beautiful Galway to discuss the latest developments in Constraint-Based Reconstruction & Analysis with the global #COBRA community. Register here: tinyurl.com/COBRAcon2022 @ines_thiele @ChEnected
My paper is one of the top cited @MolSystBiol articles for 2020-2021! doi.org/10.15252/msb.2… #TopCitedArticle
Pls RT: We have numerous openings in our international, interdisciplinary group on the west coast of Ireland. Are you a highly motivated researchers interested in pushing further the state-of-the-art in metabolic modelling of host-microbiome interactions? tinyurl.com/2bbae9aj
This was a fun project over the past 2 years! This work justified my near obsessive reading of (scientific) news on covid ...
This was a fun project over the past 2 years! This work justified my near obsessive reading of (scientific) news on covid ...
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The Virtual Metabolic.. @vmh_life
455 Followers 575 Following is a system biomedicine resource combining knowledge about human and microbial #metabolism with #disease and #nutritional information. @ines_thiele
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499 Followers 538 Following Faculty @PurdueHSCI |Computational biologist| Mother of two👶🐶| Neurodegeneration,cancer,pregnancy,toxicology research| #WomenInSTEM|@isbsci @iiscbangalore
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127 Followers 107 Following Improving aquaculture sustainability by modulating the feed-microbiome-host axis in fish. A @BlueBioCOFUND / @RCN_Norway project hosted by @UniNMBU
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706 Followers 633 Following Biochemist, Chair in Systems Medicine @imperialcollege 🇬🇧 @CNRS Research Director 🇫🇷 Adjunct Professor @McGillU 🇨🇦 human #metabolome #microbiome my views
Whole-Cell Modeling @wholecellmodels
303 Followers 223 Following Computational modeling for understanding and engineering cells
Microbial Communities.. @Galway_Microbes
84 Followers 17 Following SFI-funded @gcollinsgalway Lab, @nuigalway. #Microbiology🧫 #biofilms, microbial ecology🦠 #OneHealth🏥 #bioeconomy, sustainable #sanitation🚽, #SDGs #SDG6 #AMR
CMI @ UC San Diego @CMIdigest
2K Followers 299 Following Accelerating microbiome research via UC San Diego / industry collaborations using clinical medicine, bioengineering, biological, physical sciences and more.
Our new review in @NatRevGastroHep entitled “Fermented foods and gastrointestinal health: underlying mechanisms” is now published. Well done to @nomnommicrobe @SamuelBreselge @EiriniDimidi & @MarcolabUCDavis rdcu.be/dtjKz
New EU project "Investigation of endocrine-disrupting chemicals as contributors to progression of #MASLD"(EDC-MASLD), coordinated by @TeklaTuulia and I will start in January 2024. Looking forward! tinyurl.com/593z8dw8 #exposome #metabolomics #lipidomics #EndocrineDisruptors
And that's another @galwayscience festival done! Last visit of the year at @stjosephsbish. 800+ pupils learnt about venom, stings, bites, toxins, camouflage and constrictor snakes. Thank you all for welcoming me! I wonder... how many will join us to study zoology @SNSUniofGalway?
Delighted to make this list again - congrats to the other @UCC @Pharmabiotic researchers on the list including some new entries. All of this is really due to the fantastic creative researchers that work in our teams here in Cork.
14 UCC researchers make list of world's most influential researchers They are recognised for their significant contributions to helping make our world healthier, more sustainable and more secure. ucc.ie/en/news/2023/u… #HighlyCited2023 @Clarivate
Last Thursday, I was officially awarded a PhD in Biosciences, Genetics, Genomics, and Bioinformatics curriculum. Having defended my thesis online (on March 2022), the proclamation was a special moment that I shared with my family and my friends. @DiBio_UniPD
Congratulations to @gduffy00 @uniofgalway for being shortlisted for the prestigious 'Outstanding Research Supervisor of the Year' award in the @timeshighered #THEAwards. Garry’s dedication, hard work & passion truly deserves this recognition. Best of luck👏#Supervisor #Education
The first use of constraint-based #microbial community modelling on a person with gastrointestinal inflammation has been reported by @uniofgalway @RyanInstitute @vmh_life scientists @ines_thiele 🦠 Dive into the study here 👉 bit.ly/43FjCNB #SDG3
@RyanInstitute @uniofgalway @ines_thiele scientists carried out a metabolome-wide association analysis on over 13,000 participants, identifying 8 diet-related metabolites significantly associated with #depression 🔬 Learn more 👉 go.nature.com/45t39h3 #SDG3
🥳🦠Happy #WorldMicrobiomeDay from #Virtuome2023! In 4 consecutive years our 74 alumni advanced research along the host-microbiome-diet-drug interactions and involved >1000 community participants! @WMicrobiomeDay @Pharmabiotic @ines_thiele @GalwayCMNHS #WMD2023 #Microbiomes4Life
Nice to see you flying the @uniofgalway flag @CCThinnes , creating opportunities for future #engagedresearch partnerships for societal impact across Digital Health. That's Switzerland, Luxembourg and Strasbourg in one month!! @JimLivesey1 @hynessight @PPI_Galway @Galway_Research
A privilege to meet @Xavier_Bettel @LeoVaradkar @Yuriko_Backes @FEnschMAEE and 🇱🇺🇮🇪leaders. Promising avenues for positive societal impact, especially in Digital Health! @vmh_life @Pharmabiotic @GalwayCMNHS @AvicennaAlly @VPH_Institute @campus_engage @ERC_Research @FnrLux
Rejection of your paper or grant has NO relevance to the opinion of #research community. It is nothing but the opinion of one person. Several examples: 1. The first paper on graphene was rejected from Nature because “it did not constitute a sufficient scientific advance”.…
Professor Thiele is already living in #FutureTrials! Incredible work!!!
Research Highlight from Lin Tang: @ines_thiele and colleagues present AGORA2 (assembly of gut organisms through reconstruction and analysis, v2), an expanded resource of genome-scale metabolic reconstructions of 7000+ human gut microbes. nature.com/articles/s4159…
Why should levodopa treated #Parkinson all be on B12, B6 and folic acid? Review Ahlskog @MayoClinic levodopa elevates #homocysteine because COMT metabolism. Accumulating deficiencies #vitamins substrate for homocysteine elevation. One Flintstone enough! prd-journal.com/article/S1353-…
In new research from @RyanInstitute @uniofgalway scientists @ines_thiele, a nutritional algorithm capable of identifying dietary intervention strategies was developed and tested against two genome-scale metabolic models 💻 Check out the study here 👉 bit.ly/3Kvjo64
I'd also like to thank the researchers who made their data accessible for our analyses (@oventurelli2 @LabSonnenburg Hamaker Lab) and the great folks at @vmh_life and @ines_thiele for providing well-curated genome-scale metabolic models of gut commensal bacteria.
Individualized (personalized) medicine has traditionally included gene-drug interactions (pharmacogenomics). Now add gut microbiome-drug interactions nature.com/articles/s4158… @NatureBiotech by @heinken_almut @ines_thiele and colleagues
Now we can seriously start thinking of getting the most suited (personalized) fermented food consortium each morning nature.com/articles/s4158…
@NatureBiotech @MetExplore @GalwayCMNHS @RyanInstitute @uni_lu @CZUvPraze @UMCUtrecht @LACDR @UChicago @argonne @ines_thiele @heinken_almut Awesome job. Will help in future to treat multiple diseases and will improve the developments of personalised medicine.
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