F. Olivier Hébert @hebert_fo

Ph.D. Biology - Scientific writer @ CR-CHUM #IntegrativeBiology #evolution #genomics #CannabisScience #Bioinformatics #ClinicalTrials #EndocannabinoidSystem cliniquelacroixverte.com/fr/ Montréal, QC, Canada Joined May 2014

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F. Olivier Hébert @hebert_fo

4 years ago

@phdilly Completely novel phytocannabinoids by genetic modification/engineering of BBE-like enzymes? Would be crazy cool.

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Centre SÈVE @centre_seve

5 years ago

Des candidatures sont sollicitées chez notre membre #CentreSÉVE @idjoly @umoncton Maîtrise/Doctorat –résistance aux maladies chez le cannabis

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F. Olivier Hébert @hebert_fo

5 years ago

@landrychristian You will become a skilled bike mechanics in no time, guaranteed 🤪

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F. Olivier Hébert @hebert_fo

5 years ago

Super fun project that we worked on for a while, but finally, it's (almost) done! Cannabis has 2 MLO genes putatively involved in PM resistance and the MLO family shows interesting patterns of orthology and paralogy. Fascinating host-pathogen system that keeps on impressing me🤘

David Joly @idjoly

5 years ago

It took us a while to write it, but it is finally online on @biorxiv_plants : Genome-wide analysis of MLOs in cannabis biorxiv.org/content/10.110… /with @hebert_fo @GenomeCanada @GenomeAtlantic @nb_innovation @ACOACanada @discoverOGI @JonatanSmallMt

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F. Olivier Hébert @hebert_fo

6 years ago

@idjoly @JonatanSmallMt Great plants 👌 I love to work with them 🌱

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F. Olivier Hébert @hebert_fo

6 years ago

@naubinhorth No future

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6 years ago

@idjoly I wonder if this trait is co-selected with other traits of importance in cannabis. Some sort of "hitchhiking" trait... Can't wait to pop these little treasures!!

David Joly @idjoly

6 years ago

Variation in seed size between some of the cannabis seeds we got today... another interesting trait to investigate (at least to introgress in hemp lines)

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F. Olivier Hébert @hebert_fo

6 years ago

@Kevin_McKernan @beezerism It depends what type of statin is used though. Certain meds (e.g. rosuvastatin) are not targeted by CYP enzymes and these are relatively safe in terms of drug-drug interaction when combined with CBD.

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F. Olivier Hébert @hebert_fo

6 years ago

@idjoly 🙏🙏

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F. Olivier Hébert @hebert_fo

6 years ago

@Kevin_McKernan Yes indeed. Lots of ideas to reflect on fore sure. I was thinking of testing as many patients as possible in our cannabis clinic in Montreal to compare with population-wide data, but technically/financially challenging... No confirmed case to date among our patients🤞

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F. Olivier Hébert @hebert_fo

6 years ago

bioRxiv preprint--> disq.us/t/3phbdn6 Well thought @MediGenomics @Kevin_McKernan cannabis = essential for so many patients and these people are often at risk of contracting all sorts of pathogens/infections/illnesses. Good work guys.

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Lambert Initiative @Lambert_Usyd

6 years ago

#Endocannabinoids, anandamide & 2-AG, were protective against multiple fly #seizure model despite flies not having cannabinoid receptors - suggested to be working through #TRP channels sciencedirect.com/science/articl…

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F. Olivier Hébert @hebert_fo

6 years ago

Very excited to be part of this great collaborative work with tremendous scientists @verdanki @naubinhorth @luciegrecias @IainBarber. Awesome zombie study system and, as always, amazed to witness the tremendous capacities of parasites! Gruesome, curious and dominant creatures!

David Joly @idjoly

6 years ago

Variation in seed size between some of the cannabis seeds we got today... another interesting trait to investigate (at least to introgress in hemp lines)

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F. Olivier Hébert @hebert_fo

6 years ago

@landrychristian Kids could be politicians then !

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Kevin McKernan @Kevin_McKernan

6 years ago

The CBCAS deletion that is described in this PrePrint- biorxiv.org/content/10.110… 323 more samples sequenced with StrainSEEKV2. The Deletion is seen in the lower coverage across the 8 CBCAS genes and many of the samples have chemotypes to demonstrate lack of CBCAS expression.