jay brophy @brophyj
Slightly contrarian cardiologist & epidemiologist living and working in Montreal Canada brophyj.com Joined January 2009-
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@DrToddLee @drjohnm @theheartorg Why would anyone be surprised? 27years ago a RCT of nearly 7000 patients found data compatible with a possible 9% mortality reduction CI .91-1.07 & hospital decreased 28% CI 0.66 to 0.79
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@FAircanada46710 So it goes bad to worse. The lineup for the AC lounge, included rather worthlessly with the purchase our business class tickets, is more than 1 hour. Needless to say will find other eateries.
So AC e boarding downloads still not working. They don't seem to really care. Looks like I'll need a printer to board later today. Thanks for the lack of help. @AirCanada
@AirCanada Perhaps AC would like to me to try later AFTER my flight has departed!
@ASayedMD This was amazing work by you from conception, through analysis to submission. Congratulations!
@DrToddLee @FralickMike @GIMtoronto Hopefully will be submitted within the next 2 weeks
@kaulcsmc Desk reject in all cases, doesn’t meet our priorities, see yeah later. And oh by the way, good luck and look forward to other submissions from you in the future
First time publishing on Medium medium.com/@jbrophy115/is…
Just my 2 cents, but 👎👎👎to the new @twitter name and logo
New @NEJM study nejm.org/doi/full/10.10… median 5.1 years MACE = 4.81/1000PY in #pitavastatin and 7.32/1000PY in placebo. Text claims 5 year NNT = 106. What am I missing? Looks like 5 year NNT = 1/(7.32/1000-4.81/1000) = 398 to me. Statistically significant but clinically?
Sad day - my old friend towed way to its demise. But broken power steering, gas leak requiring open windows, battery needing constant jumping, slow tire leak, and the family of mice living in the trunk, just added up to too much. Last drive yesterday, 20 years was a good run!
@drjohnm @f2harrell @kaulcsmc @beenwrekt @VPrasadMDMPH “Reporting the LR may improve the interpretation of clinical trials” I don’t think so. Large LR mostly showing overly enthusiastic Ha being proposed. To assess how much support exists for the null (+/- range of equivalence) need the full probability distribution @arthur_alb1
No phone with me, so this is the best I can do to show the beauty of an early morning country run.
Have a short article deals with teaching, research, biases, critical reading, and foundational past research. No natural home and no interested publisher. So 1st use of medium.com medium.com/@james.brophy/… Also available on my webpage brophyj.com/post/2023-03-2…
@DrToddLee @kaulcsmc Ignore the results for a moment. A priori, do you think in NA context, equipoise existed to do this trial? We know this drug makes you bleed and in the context of recent stroke…. I certainly would never have participated.
@DrToddLee @robyn_s_lee So sorry Todd. My profound condolences on your loss.
@f2harrell @VPrasadMDMPH ChatGPT no better - how to interpret - RR 1.01, 95% CI 0.72-1.42? “RR= 1.01 means no significant Δ in the outcome between intervention & control group. The 95% CI range indicates that we are 95% confident that the true effect of the intervention lies somewhere within that range."
John Mandrola, MD @drjohnm
70K Followers 2K Following Heart rhythm doc, writer for @Medscape, host of This Week in Cardiology podcast, editor of Sensible Medicine. The more you see, the harder medicine gets.
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Frank Harrell @f2harrell
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Venk Murthy MD PhD @venkmurthy
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Todd C. Lee @DrToddLee
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Patrick Myers @pomyers
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RUI M S ALMEIDA @RMSSAA
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0 Followers 9 Following Im a kid with a very very normal life, an ordinary person doesn't write a bio "As long as there is life there is hope"
金寶娜-朵朵小�... @alexustaliyaxo
65 Followers 114 Following 30 歲以上朋朋看過來 小課堂不定時開課 內容超豐富 加客服 line 就能知道 未滿年齡謝絕加入 全是成熟玩法 保證老闆開心滿意 快加 line 了解詳情 #基隆 #雲林
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34 Followers 841 Following Phillipians 4 vs 13 I can do all things through Christ who strengthens me 💪 🧑⚕️👩❤️👨💉💊🩺
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179 Followers 2K Following lovely to meet new friends No Dm follow for follow back No crypto or Money
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ARATA ⚡️ @seiitiarata
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Renée Drolet, Ph.D.�... @DroletRenee
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useR! 2020 @useR2020stl
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